Abstracts tagged "informatics"

Abstract Number: 2070 • ACR Convergence 2023
Augmenting Medical Education: An Evaluation of GPT-4 and ChatGPT in Answering Rheumatology Questions from the Spanish Medical Licensing Examination
Alfredo Madrid García¹, zulema Rosales², Dalifer Freites², Inés Pérez Sancristóbal³, Benjamin Fernandez³ and Luis Rodríguez Rodríguez³, ¹Fundación Investigación Biomédica Hospital Clínico San Carlos, Madrid, Spain, ²Hospital Clínico San Carlos, Madrid, Spain, ³Hospital Clinico San Carlos, Madrid, Spain
Background/Purpose: The emergence of Large Language Models (LLM) with remarkable performance such as GPT-4 and ChatGPT, has led to an unprecedented uptake in the population.…
Abstract Number: 2323 • ACR Convergence 2023
An Electronic Health Record-Based Algorithm for Predicting Systemic Lupus Erythematosus Flares: Integrating Clinical Factors and Social Determinants of Health
Yu Huang¹, Lixia Yao², zhengkang Fan³, Jingchuan Guo¹ and Jiang Bian¹, ¹University of Florida, Gainesville, FL, ²Polygon Health Analytics LLC, Chalfont, PA, ³University of Florida, Gainsville, FL
Background/Purpose: Systemic lupus erythematosus (SLE) has a relapsing-remitting course, with patients experiencing disease activity flares over time. Flares and prolonged disease activity are associated with…
Abstract Number: 2586 • ACR Convergence 2023
A Novel Blood-Based Assay Differentiates Seropositive and Seronegative Rheumatoid Arthritis from Healthy Individuals and Those with Other Inflammatory Diseases or Osteoarthritis
Peter C. Taylor¹, Jenya Antonova², Jennifer Geis³, Katharine Dilger³, David Chernoff⁴, Diana Abdueva³, Nancy Shadick⁵ and Michael Weinblatt⁶, ¹Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ²Compass Strategy and Research, Inc., San Francisco, CA, ³Aqtual Inc., Hayward, CA, ⁴Chernoff Consulting, Sausalito, CA, ⁵Brigham and Women's Hospital, Boston, MA, ⁶Harvard Medical School, Waban, MA
Background/Purpose: Non-invasive differentiation of seropositive and seronegative rheumatoid arthritis (RA) from other conditions has been limited in the current practice. We aimed to evaluate the…
Abstract Number: 0163 • ACR Convergence 2023
Uncovering Discrepancies: Analysis of Glucocorticoid Exposure Among Patients with Rheumatoid Arthritis in Electronic Health Record Data versus Medicare Claims
Jing Li¹, Julia Kay¹, Sharon Abada¹, Andriko Palmowski², Rachael Stovall¹, Jinoos Yazdany³ and Gabriela Schmajuk⁴, ¹University of California San Francisco, San Francisco, CA, ²Charité - Universitätsmedizin Berlin, Berlin, Germany, ³University of California, General Department of Medicine, Division of Rheumatology, San Francisco, CA, ⁴UCSF / SFVA, San Francisco, CA
Background/Purpose: Understanding glucocorticoid (GC) exposure is critical for observational analyses in rheumatology. However, obtaining an accurate measure of GC exposure, including dosage and duration, has…
Abstract Number: 0175 • ACR Convergence 2023
Predicting Cost-Related Medication Non-Adherence in US Adults with Chronic Arthritis: A Machine Learning Approach
Ashkan Ara¹, Matthew Chenoweth¹ and Christopher Scannell², ¹University of California Los Angeles, Los Angeles, CA, ²UCLA / West Los Angeles VA Medical Center, Los Angeles, CA
Background/Purpose: Cost-related medication non-adherence (CRN) occurs when patients are unable to follow their prescribed medication regimen due to financial constraints, such as high costs or…
Abstract Number: 0341 • ACR Convergence 2023
Patient Perspectives on the Usability of a Rheumatoid Arthritis Patient-reported Outcomes Electronic Health Record-based Dashboard: A Mixed-Methods Study
Cherish Wilson¹, Catherine Nasrallah², Alicia Hamblin², Lindsay Jacobsohn², Cammie Young³, Cammie Young³, Mary Nakamura⁴, Andrew Gross², Judith Ashouri², Brett Dietz², Mehrdad Matloubian², Jinoos Yazdany⁵ and Gabriela Schmajuk¹, ¹UCSF / SFVA, San Francisco, CA, ²University of California San Francisco, San Francisco, CA, ³University of California San Francisco, Oakland, CA, ⁴UCSF/SFVAHCS, San Francisco, CA, ⁵University of California, General Department of Medicine, Division of Rheumatology, San Francisco, CA
Background/Purpose: Shared decision making, health literacy, and effective communication around patient-reported outcomes (PROs) are vital components to a treat-to-target approach in rheumatoid arthritis (RA) patients.…
Abstract Number: 0353 • ACR Convergence 2023
Validation of Claims-based Algorithms for Newly Diagnosed Juvenile Idiopathic Arthritis Using Machine Learning Methods
Patricia Hoffman¹, Lauren Parlett², Daniel Beachler², Daniel Reiff³, Sarah McGuire¹, Sonia Pothraj¹, Lakshmi Moorthy¹, Cynthia Salvant⁴, Dawn Koffman⁵, Sanika Rege⁵, Cecilia Huang⁵, Matthew Iozzio⁵, Kevin Schott², Kevin Haynes⁶, Amy Davidow⁷, Stephen Crystal⁸, Tobias Gerhard⁵, Brian Strom⁹, Carlos Rose¹⁰ and Daniel Horton⁴, ¹Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ²Carelon, Wilmington, DE, ³University of Alabama at Birmingham, Birmingham, AL, ⁴Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ⁵Rutgers Center for Pharmacoepidemiology and Treatment Science, New Brunswick, NJ, ⁶Janssen Pharmaceuticals, Raritan, NJ, ⁷New York University, New York, NY, ⁸Rutgers University, New Brunswick, NJ, ⁹Rutgers, State University of New Jersey, New Brunswick, NJ, ¹⁰Thomas Jefferson University, Philadelphia, PA
Background/Purpose: Administrative claims databases represent important settings for studying large populations with juvenile idiopathic arthritis (JIA), but prior efforts to validate diagnostic algorithms for JIA…
Abstract Number: 0807 • ACR Convergence 2023
Inferring Disease Activity Scores and Low Disease Activity at Registry Visits Based on Structured and Narrative Data from Electronic Health Records
David Cheng¹, Dana Weisenfeld², Kumar Dahal², Qing Liu², Vidul Ayakulangara Panickan³, Mary Jeffway², Thany Seyok², Gregory McDermott², Michael Weinblatt⁴, Nancy Shadick⁵, Tianxi Cai⁶ and Katherine Liao², ¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Harvard Medical School, Boston, MA, ⁴Harvard Medical School, Waban, MA, ⁵Brigham and Women's Hospital, Boston, MA, ⁶Harvard T.H. Chan School of Public Health, Boston, MA
Background/Purpose: Real-world data including electronic health records (EHRs) are a promising resource for learning to optimize treatment strategies for rheumatoid arthritis (RA). A major challenge…
Abstract Number: 006 • 2023 Pediatric Rheumatology Symposium
Implementation of Automated Depression Screening in Patients with Lupus in a Tertiary Pediatric Rheumatology Clinic
Lauren Harper¹, Alana Goldstein-Leever¹, James Gallup¹, Vidya Sivaraman², Stacy Ardoin¹, Kyla Driest¹, Evan Mulvhihill³ and Alysha Taxter⁴, ¹Nationwide Children's Hospital, Columbus, OH, ²Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, ³Nemours Children's Hospital, ⁴Nationwide Children's Hospital, Columbus, OH

Background/Purpose: Patients with chronic rheumatic conditions, particularly lupus, have higher rates of depression, which significantly impacts their lives and can lead to poor medication compliance…
Abstract Number: 018 • 2023 Pediatric Rheumatology Symposium
Using the Electronic Health Record to Identify Subjects with Rheumatic Disease
Alysha Taxter¹, Matthew Basiaga², Rajdeep Pooni³, Caitlan Pinotti⁴, Lisa Buckley⁵ and CARRA Registry Investigators⁶, ¹Nationwide Children's Hospital, Columbus, OH, ²Mayo Clinic, Rochester, MN, ³Stanford University, Palo Alto, CA, ⁴Duke, Durham, NC, ⁵Vanderbilt University Medical Center, Nashville, TN, ⁶CARRA, Washington, DC
Background/Purpose: Research teams spend hours manually searching the electronic health records (EHRs) to identify potential candidates eligible for recruitment to the Childhood Arthritis and Rheumatology…
Abstract Number: 107 • 2023 Pediatric Rheumatology Symposium
Validation of Serious Adverse Event Reporting in a Multicenter Registry
Matthew Basiaga¹, Rajdeep Pooni², Caitlan Pinotti³, Lisa Buckley⁴, Alysha Taxter⁵ and CARRA Registry Investigators⁶, ¹Mayo Clinic, Rochester, MN, ²Stanford University, Palo Alto, CA, ³Duke, Durham, NC, ⁴Vanderbilt University Medical Center, Nashville, TN, ⁵Nationwide Children's Hospital, Columbus, OH, ⁶CARRA, Washington, DC
Background/Purpose: Children with rheumatic disease frequently require management with immune suppressing medications. The benefits of these interventions often outweigh the risks, however serious adverse events…
Abstract Number: 115 • 2023 Pediatric Rheumatology Symposium
Development of an Electronic Clinical Phenotype to Identify Potential Study Subjects with Juvenile Arthritis
Alysha Taxter¹, Marc Natter², Min-Lee Chang², Laura Schanberg³, Valarie Morrow⁴, Eveline Wu⁵, Tedryl Bumpass⁴, Alex Fist⁴, Meg Waite⁶, Vincent Del Gaizo⁷, Melanie Kohlheim⁷ and CARRA Registry Investigators⁷, ¹Nationwide Children's Hospital, Columbus, OH, ²Boston Children's Hospital, Boston, MA, ³Duke University Medical Center, Durham, NC, ⁴Duke University, Durham, NC, ⁵UNC Chapel Hill, Chapel Hill, NC, ⁶Boston Children's Hospital, Boston, MA, ⁷CARRA, Washington, DC
Background/Purpose: The LIMIT-JIA trial is the first study of the use of biologic therapy to prevent disease extension in children with newly diagnosed, uncomplicated, oligo-articular…
Abstract Number: 1513 • ACR Convergence 2022
Identification of MRI Lesions Indicative of Spondyloarthritis Diagnosis from the Axial Spondyloarthritis International Society (ASAS) MRImagine Multi-Reader Scoring Dataset Using the Chi-Squared Automatic Interaction Detection Algorithm (CHAID)
Stephanie Wichuk¹, Walter P Maksymowych², Robert G Lambert¹, Abhilash Hareendranathan³ and Jacob Jaremko¹, ¹University of Alberta, Edmonton, AB, Canada, ²Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Several types of active and structural lesions have been identified on sacroiliac joint MRI of spondyloarthritis (SpA) patients. Various combinations of these lesions may…
Abstract Number: 1514 • ACR Convergence 2022
Self-referral Strategy for Early Diagnosis of Axial Spondyloarthritis- Preliminary Analysis from Finding Axial Spondyloarthritis Study
Abhijeet Danve, Yale University, New Haven, CT
Background/Purpose: Lack of timely rheumatology referral for suspected axial spondyloarthritis (axSpA) is a major contributor to delayed diagnosis in patients with chronic back pain (CBP).…
Abstract Number: 1739 • ACR Convergence 2022
Single-Cell Characterization of the TCR Repertoire Across Tissue and Blood in Rheumatoid Arthritis
Garrett Dunlap¹, Aaron Wagner², Nida Meednu³, Anna Jonsson⁴, Fan Zhang⁵, Kevin Wei⁶, Paul Utz⁷, William Robinson⁷, Holden Maecker⁷, Judith James⁸, Joel Guthridge⁸, S. Louis Bridges, Jr.⁹, Laura Donlin⁹, Susan Goodman⁹, Edward DiCarlo⁹, Vivian Bykerk⁹, Christopher Ritchlin¹⁰, Darren Tabechian¹¹, James Lederer⁴, Ellen Gravallese¹², Mandy McGeachy¹³, Gary S. Firestein¹⁴, Peter Gregersen¹⁵, Diane Horowitz¹⁶, David Boyle¹⁷, Laura Geraldino-Pardilla¹⁸, Harris Perlman¹⁹, Arthur Mandelin²⁰, Joan Bathon¹⁸, Laura Hughes²¹, V. Michael Holers²², Kevin D Deane²³, Larry Moreland²², Andrew Filer²⁴, Costantino Pitzalis²⁵, Lindsy Forbess²⁶, Ami Ben-artzi²⁷, Karen Salomon-Escoto²⁸, Soumya Raychaudhuri⁴, Michael Brenner¹², Accelerating Medicines Partership (AMP) RA/SLE Network²⁹, Andrew McDavid², Jennifer Anolik³ and Deepak Rao⁴, ¹Harvard University, Boston, MA, ²University of Rochester, Rochester, NY, ³University of Rochester Medical center, Rochester, NY, ⁴Brigham and Women's Hospital, Boston, MA, ⁵University of Colorado, Aurora, CO, ⁶Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁷Stanford University School of Medicine, Palo Alto, CA, ⁸Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁹Hospital for Special Surgery, New York, NY, ¹⁰Allergy, Immunology and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY, ¹¹URMC, Rochester, NY, ¹²Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ¹³University of Pittsburgh, Pittsburgh, PA, ¹⁴University of California, San Diego, San Diego, CA, ¹⁵The Feinstein Inst for Med Research, Larchmont, NY, ¹⁶Northwell Health, Jericho, NY, ¹⁷UCSD, La Jolla, CA, ¹⁸Columbia University, New York, NY, ¹⁹Northwestern University, Chicago, IL, ²⁰Northwestern University Feinberg School of Medicine, Chicago, IL, ²¹University of Alabama at Birmingham, Birmingham, AL, ²²University of Colorado, Denver, CO, ²³University of Colorado Denver Anschutz Medical Campus, Denver, CO, ²⁴University of Birmingham, Birmingham, United Kingdom, ²⁵Queen Mary University of London, London, United Kingdom, ²⁶Cedars-Sinai Medical Center, Los Angeles, CA, ²⁷Ami Ben-Artzi, MD Inc., Beverly Hills, CA, ²⁸University of Massachusetts Medical School, Worcester, MA, ²⁹National Institutes of Health, Washington, DC
Background/Purpose: In rheumatoid arthritis (RA), T cells represent a large proportion of the immune population present in inflamed joint synovium, and subsets of both CD4+…

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