Abstracts tagged "informatics"

Abstract Number: 0816 • ACR Convergence 2024
Distinct Transcript and Protein Dysregulation Patterns in Dermatomyositis and Systemic Lupus Erythematosus
James Ward¹, Mythri Ambatipudi², Zerai Manna³, Michael Smith⁴, Melissa de los Reyes⁵, Adam Schiffenbauer⁶, Saifur Rahman⁷, Kamelia Zerrouki⁵, Fredrick Miller¹, Mariana Kaplan⁸, Jian-Liang Li¹, Kerry Casey⁹, Lisa Rider¹⁰ and Sarfaraz Hasni⁶, ¹National Institute of Environmental Health Sciences, NIH, Durham, NC, ²Harvard Medical School, Boston, MA, ³NIH, Bethesda, MD, ⁴Horizon Therapeutics, Alexandria, VA, ⁵AstraZeneca, Gaithersburg, MD, ⁶NATIONAL INSTITUTES OF HEALTH, Bethesda, MD, ⁷AstraZeneca, Gaithersburg, ⁸NIAMS/NIH, Bethesda, MD, ⁹Regeneron Pharmaceuticals, Terrytown, NY, ¹⁰NIEHS, NIH, Garrett Park, MD
Background/Purpose: Systemic lupus erythematosus (SLE) and dermatomyositis (DM) are hypothesized to be triggered by shared genetic and environmental factors leading to aberrant activation of innate…
Abstract Number: 0901 • ACR Convergence 2024
Intergenic Alu Elements Are Uniquely Expressed in Dermatomyositis and Correlate with Interferon Stimulated Genes
Rayan Najjar¹, Andrew Mammen² and Tomas Mustelin¹, ¹University of Washington, Seattle, WA, ²NIH, Bethesda, MD
Background/Purpose: As genes constitute < 2% of our genomes, there is a need to explore potential roles of other genomic elements in autoimmune disease. We…
Abstract Number: 1063 • ACR Convergence 2024
AI –Driven Precision in Rheumatologic Emergencies: Unveiling the Capability of Top Healthcare Chatbots
Abi Fadairo-Azinge¹, Jinoos Yazdany² and Matt Sakumoto³, ¹University of California San Francisco UCSF, SAN-FRANCISCO, CA, ²University of California San Francisco, San Francisco, CA, ³Sutter Health Virtual-First Primary Care Physician & CMIO Sutter West Bay Region Sutter Health,Assistant Clinical Professor,Department of Medicine, UCSF, SAN-FRANCISCO, CA
Background/Purpose: Rheumatologic emergencies are severe, with mortality rates up to 50% even with timely intervention. Associated morbidity includes permanent organ failure and significant disability. This…
Abstract Number: 1076 • ACR Convergence 2024
Assessing the Reliability of ChatGPT on Recombinant Zoster Vaccination for Patients with Rheumatic and Musculoskeletal Diseases
Akhil Sood, Pegah Jahangiri, Amanda Moyer and Janice Lin, Stanford University, Palo Alto, CA
Background/Purpose: As artificial intelligence (AI) platforms continue to evolve, large language models (LLMs) such as ChatGPT by OpenAI are increasingly being utilized by patients and…
Abstract Number: 1932 • ACR Convergence 2024
Effects of Clinical Decision Support on Transition Readiness Assessment in Pediatric Rheumatology
Chrisana Pokorny¹ and Bethany Marston², ¹University of Rochester, Webster, NY, ²University of Rochester, Rochester, NY
Background/Purpose: Pediatric to adult transition is often challenging among young adults with rheumatic diseases. Structured transition programs can improve adherence to care, quality of life,…
Abstract Number: 1944 • ACR Convergence 2024
Enhancing Rheumatology Consultations with AI-Powered Triage: The ReumAI Pilot Study
Antonio Gomez-Centeno¹, Mariña Sabaris-Vilas², Javier Segura-Sanchez³ and Fermin Garcia-Sancho³, ¹Hospital Quiron Barcelona, Barcelona, Spain, ²Hospital Quirón Barcelona, Barcelona, Spain, ³TamoeInnovation S.L., Madrid, Spain
Background/Purpose: In private healthcare settings, patients often have direct access to specialists without prior referral. However, in rheumatology, this can lead to inefficiencies due to…
Abstract Number: 2151 • ACR Convergence 2024
Rheumatology on Reddit: A Descriptive Analysis
Alfredo Madrid García¹, Beatriz Merino Barbancho², Inés Pérez - Sancristóbal³, Dalifer Freites Nuñez⁴, Luis Rodriguez Rodriguez⁵, lydia Abasolo Alcazar⁶, Leticia Leon⁷ and Benjamin fernandez-Gutierrez⁷, ¹Fundación para la Investigación Biomédica del Hospital Clínico San Carlos (IDISCC), Madrid, Madrid, Spain, ²Life supporting technologies. Escuela Técnica Superior de Ingenieros de Telecomunicación. Universidad Politécnica de Madrid., Madrid, Spain, ³Department of Rheumatology, Hospital Clinico San Carlos,, Madrid, Madrid, Spain, ⁴Hospital Clínico San Carlos. Madrid. Spain., Madrid, Spain, ⁵Hospital Clinico San Carlos, Madrid, Madrid, Spain, ⁶IdISSC. HCSC, Madrid, Spain, ⁷Hospital Clinico San Carlos, Madrid, Spain
Background/Purpose: Over the past decade, social media data have gained special interest across various sectors, specially in medicine where these data are being utilized for…
Abstract Number: 0001 • ACR Convergence 2024
Type I Interferon and Anifrolumab Effects on Bone Marrow and Blood Plasma Cells in Systemic Lupus Erythematosus
Diana Alzamareh¹, Nida Pellett², Daria Krenitsky², Wesley Durrett¹, Javier Rangel-Moreno¹, Jennifer Anolik² and Jennifer Barnas¹, ¹University of Rochester, Rochester, NY, ²University of Rochester Medical Center, Rochester, NY
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of pathogenic anti-nuclear antibodies (ANA) by plasma cells (PC). Importantly, long-lived plasma…
Abstract Number: 2183 • ACR Convergence 2024
Accuracy of AI Tools for Diagnosis of Connective Tissue Disease
Indira Sriram¹, Gabriel Tarshish² and Megan Curran², ¹University of Colorado, Aurora, CO, ²Children's Hospital Colorado, Aurora, CO
Background/Purpose: In this work, we study the ability of generative artificial intelligence (AI) based tools to diagnose pediatric rheumatological diseases. Specifically, we seek to answer…
Abstract Number: 0125 • ACR Convergence 2024
Electronic Health Record Rule-Based Computable Phenotype of Antiphospholipid Syndrome
Emily Balczewski¹, Amala Ambati², Wenying Liang¹, Jacqueline Madison¹, Yu Zuo¹, Karandeep Singh³ and Jason Knight¹, ¹University of Michigan, Ann Arbor, MI, ²University of Michigan, Toledo, OH, ³University of California -- San Diego, San Diego, CA
Background/Purpose: Electronic health record (EHR) data provide a widely available, inexpensive, and information-rich tool that is underutilized in the research of rare diseases like antiphospholipid…
Abstract Number: 2192 • ACR Convergence 2024
Utilizing Electronic Health Record Pre-Consultation Data to Create a Predictive Algorithm for Diagnosis of Chronic Pediatric Rheumatic Conditions
Kendra Lauer¹, Kyla Driest², Laura Pratt³ and Alysha Taxter², ¹Nationwide Children's Hospital, Dublin, OH, ²Nationwide Children's Hospital, Columbus, OH, ³Nationwide Children's Hospital/The Ohio State University College of Medicine, Columbus, OH
Background/Purpose: With the current workforce shortage, wait times for initial consultation with pediatric rheumatology are lengthy and many referrals do not result in a rheumatic…
Abstract Number: 0126 • ACR Convergence 2024
Underdiagnosis Prediction Fingerprint for Antiphospholipid Syndrome Derived from Electronic Health Record Data
Emily Balczewski¹, Amala Ambati², Wenying Liang¹, Jacqueline Madison¹, Yu Zuo¹, Karandeep Singh³ and Jason Knight¹, ¹University of Michigan, Ann Arbor, MI, ²University of Michigan, Toledo, OH, ³University of California -- San Diego, San Diego, CA
Background/Purpose: Antiphospholipid syndrome (APS) is a rare autoimmune disease that is likely to demonstrate improved outcomes with earlier diagnosis and treatment. However, given APS’s complex,…
Abstract Number: 2405 • ACR Convergence 2024
Chat-GPT Performance in Diagnosis of Rheumatological Diseases: A Comparison with Specialist’s Opinion
Lucas Goncalves¹ and Carlos Antonio Moura², ¹Bahiana School of Medicine and Public Health, Salvador, Bahia, Brazil, ²Bahiana School of Medicine and Public Health, Santo Antonio's Hospital, Sister Dulce's Social Works, Universidade Salvador (UNIFACS), Salvador, Bahia, Brazil
Background/Purpose: Despite Generative Pretrained Transformer Chat (Chat-GPT) is an artificial intelligence tool with the potential to assist doctors in diagnosing and treating patients, little is…
Abstract Number: 0372 • ACR Convergence 2024
Readability Analysis of the American College of Rheumatology Patient Education Material
Quynh Giao Nguyen, Arianna Moss and Priyanka Iyer, University of California Irvine, Orange, CA
Background/Purpose: Patient education materials are an important resource to improve health education. According to the American Medical Association (AMA), education materials should not be written above a 6th grade…
Abstract Number: 2536 • ACR Convergence 2024
Trans-Disease Microbial Biomarkers of Protection and Pathogenesis in Autoimmune Conditions: Results from the AMP AIM Consortium
Kevin Bu¹, Rebecca Blank², Adam Cantor¹, Alba Boix-Amoros³, Jose Scher⁴ and Jose Clemente¹, and Accelerating Medicines Partnership and Immune-Mediated Diseases Network (AMP AIM), ¹Icahn School of Medicine at Mount Sinai, New York, NY, ²NYU, New York, NY, ³Icahn School of Medicine, New York, NY, ⁴New York University School of Medicine, New York, NY
Background/Purpose: Autoimmune and immune-mediated diseases (AIMDs) affect over 20 million Americans. Although AIMDs have distinct symptomatology, there is significant overlap in their treatment, suggesting overlap…

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