Abstracts tagged "inflammatory arthritis"

Abstract Number: 3250 • 2015 ACR/ARHP Annual Meeting
Systemic Inflammation and Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, Laura Frey-Law², Devyani Misra¹, Michael C. Nevitt³, Lars Arendt-Nielsen⁴, Emily K. Quinn⁵ and Cora E. Lewis⁶, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²UIowa, Iowa City, IA, ³Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁴Aalborg University, Aalborg, Denmark, ⁵Data Coordinating Center, Boston University School of Public Health, Boston, MA, ⁶Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Pain sensitization is associated with pain severity in knee osteoarthritis (OA), but its cause in humans is not well-understood. We recently demonstrated that local…
Abstract Number: 152 • 2015 ACR/ARHP Annual Meeting
Anti-CCP Positive Patients without Clinical Synovitis Progress If Ultrasound Positive
Jackie L. Nam¹, Elizabeth M.A. Hensor¹, Laura Hunt¹, Philip G. Conaghan², Richard J. Wakefield¹ and Paul Emery³, ¹NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ³NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom
Background/Purpose: To determine whether ultrasound can identify which anti-cyclic citrullinated peptide (anti-CCP) antibody positive patients with musculoskeletal (MSK) symptoms and without clinical synovitis progress to…
Abstract Number: 3265 • 2015 ACR/ARHP Annual Meeting
Sustaining Employment with Arthritis: Can Existing Workplace Policies and Accommodations Make a Difference?
Monique A.M. Gignac^1,2, Elizabeth M. Badley³, Dorcas Beaton⁴, Vicki Kristman⁵, Cameron Mustard⁶, Peter Smith⁶ and Selahadin Ibrahim⁶, ¹Instititue for Work and Health, Toronto, ON, Canada, ²Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ³Toronto Western Research Institute, Toronto, ON, Canada, ⁴St. Michael's Hospital, Toronto, ON, Canada, ⁵Lakehead University, Toronto, ON, Canada, ⁶Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: Despite improved treatment, many individuals with inflammatory arthritis (IA) and osteoarthritis (OA) report difficulties working, reduced productivity and elevated absenteeism. Lacking is research on…
Abstract Number: 189 • 2015 ACR/ARHP Annual Meeting
Indocyanine Green (ICG) -Enhanced Fluorescence Optical Imaging (FOI) in Patients with Active Rheumatoid Arthritis; A Comparative Study with Ultrasound and Association with Biomarkers
Shin-ya Kawashiri^1,2, Ayako Nishino³, Masataka Umeda³, Shoichi Fukui¹, Yoshikazu Nakashima³, Naoki Iwamoto¹, Kunihiro Ichinose¹, Hideki Nakamura¹, Tomoki Origuchi⁴, Kiyoshi Aoyagi² and Atsushi Kawakami³, ¹Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Department of Immunology and Rheumatology, Nagasaki University, Nagasaki, Japan, ⁴Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Methods: Twenty-five active RA patients (mean disease durations 7.5 years and DAS28-ESR 5.90) who fulfilled 2010 RA classification criteria were consecutively enrolled in this study.…
Abstract Number: 3266 • 2015 ACR/ARHP Annual Meeting
Keeping Baby Boomers in the Labour Force Longer: What Does It Mean for Workers with Arthritis?
Monique A.M. Gignac¹, Elizabeth M. Badley², Dorcas Beaton³, Vicki Kristman⁴, Cameron Mustard⁵, Peter Smith⁵ and Selahadin Ibrahim⁵, ¹Instititue for Work and Health, Toronto, ON, Canada, ²Toronto Western Research Institute, Toronto, ON, Canada, ³St. Michael's Hospital, Toronto, ON, Canada, ⁴Lakehead University, Toronto, ON, Canada, ⁵Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: There is concern that an aging workforce results in lost skills and high burden on pension programs. This has resulted in the dissolution of…
Abstract Number: 201 • 2015 ACR/ARHP Annual Meeting
Innate Lymphoid Cells Are Present at Normal Human Enthesis Providing a Potential Mechanism for Spondyloarthropathy Pathogenesis
Richard Cuthbert¹, Evangelos M. Fragkakis¹, Peter Millner², Robert Dunsmuir², Yasser El-Sherbiny¹ and Dennis McGonagle¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Department of Spinal Surgery, National Health Service, Leeds, United Kingdom
Background/Purpose: The pathogenesis of murine spondyloarthropathy (SpA) has been intimately linked to the presence of IL-23 responsive, innate like lymphocytes at peripheral and spinal enthesis.…
Abstract Number: 2559 • 2014 ACR/ARHP Annual Meeting
Vitamin D insufficiency and Deficiency in Two European Cohorts of Patients with Inflammatory Rheumatic Disorders
Alessandra Vacca¹, Giovanni Porru¹, Grazia Dessole¹, Alessandro Mathieu¹, Catherine Cormier², Yvonne Fulla², Andre Kahan² and Yannick Allanore³, ¹Unit and Chair of Rheumatology, University Hospital of Cagliari, Cagliari, Italy, ²Rheumatology A Department, Cochin Hospital, APHP, Paris Descartes University, Paris, France, ³Paris Descartes University, Rheumatology A Department and INSERM U1016, Cochin Hospital, Paris, France
Background/Purpose Vitamin D plays an important role in the modulation of immune system and epidemiologic data indicate low vitamin D levels in autoimmune diseases such…
Abstract Number: 2442 • 2014 ACR/ARHP Annual Meeting
Aligning Ethics with Digital Health Technologies and Shared Decision-Making: Interview Accounts of Patients and Clinicians
Anne F. Townsend^1,2,3,4, Paul Adam⁵, Jenny Leese⁶, Linda C. Li^6,7, Michael McDonald², Sheila Kerr⁸, Gordon Whitehead⁸ and Catherine Backman^6,9, ¹Qualitative Research, Arthritis Research Centre of Canada, Richmond, BC, Canada, ²Maurice Young Centre for Applied Ethics, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada, ³Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, BC, Canada, ⁴University of British Columbia, Vancouver, BC, Canada, ⁵Mary Pack Arthritis Centre, Vancouver, BC, Canada, ⁶Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁷Physical Therapy, University of British Columbia, Vancouver, BC, Canada, ⁸Arthritis Patient Advisory Board, Richmond, BC, Canada, ⁹Department of Occupational Science & Occupational Therapy, University of British Columbia, Vancouver, BC, Canada
Background/Purpose Medical ethics evolves as health care develops. Digital health technologies are transforming health care delivery and patient and clinician relationships. Ethical approaches are shifting…
Abstract Number: 2307 • 2014 ACR/ARHP Annual Meeting
Cardiovascular Disease Prevention in Rheumatologic Disease: Assessing Screening in a Primary Care Setting
Micaela Bayard¹ and Magdalena Cadet², ¹Rheumatology, New York Hospital of Queens/ Weill Cornell Medical Center, New York, NY, ²Rheumatology and Immunology, Duke University School of Medicine, Durham, NC
Background/Purpose: To determine the proportion of patients diagnosed with rheumatologic disease receiving preventive health care according to US Preventive Services Task Force recommendations with emphasis…
Abstract Number: 2140 • 2014 ACR/ARHP Annual Meeting
Agreement Among FDG-PET/CT, Ultrasound and Physical Examination in Patients with Inflammatory Arthritis
Alexis Ogdie¹, Shiv Sehra², Viviane Khoury³, Yihui Jiang⁴, Shawn Rose⁵, Nehal N. Mehta⁶, Sally W. Pullman-Mooar⁷, Abass Alavi⁸, Joel Gelfand⁹ and Joshua Baker¹⁰, ¹Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, ²Rheumatology, University of Pennsylvania, Philadelphia, PA, ³Department of Radiology, University of Pennsylvania, Philadelphia, PA, ⁴Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, ⁶Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA, ⁷Rheumatology, University of Pennsylvania and Philadelphia Veterans Hospital, Philadelphia, PA, ⁸Department of Radiology/Division of Nuclear Medicine, University of Pennsylvania, Philadelphia, PA, ⁹Dermatology and Epidemiology, University of Pennsylvania., Philadelphia, PA, ¹⁰Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA
Background/Purpose: The lack of tools to accurately measure and quantify joint inflammation is a challenging problem in the study of inflammatory arthritis. No gold standard…
Abstract Number: 1074 • 2014 ACR/ARHP Annual Meeting
A Meta-Analysis of the Risk of Venous Thromboembolism in Inflammatory Rheumatic Diseases
Jason J Lee¹ and Janet E. Pope², ¹Medicine/Rheumatology, University of Western Ontario, London, ON, Canada, ²St Joseph Health Care, London, ON, Canada
Background/Purpose: We performed a meta-analysis investigating the risk of developing deep vein thrombosis (DVT) and/or pulmonary embolisms (PE) in patients with inflammatory arthritis, vasculitis, and…
Abstract Number: 1006 • 2014 ACR/ARHP Annual Meeting
Interleukin-4 As Promising, Anti-Inflammatory Transgene for Gene Therapeutic Application in Joint Diseases
Annemarie Lang¹, Johannes Neuhaus², Moritz Pfeiffenberger³, Erik Schroeder⁴, Frank Buttgereit⁵, Michael F. G. Schmidt³ and Timo Gaber⁶, ¹Berlin-Brandenburg School of Regenerative Therapies (BSRT), Berlin, Germany, ²Department of Veterinary Medicine, Research Center of Medical Technology and Biotechnology, Bad Langensalza, Germany, ³Department of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany, ⁴Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ⁵Charité University Hospital, Berlin, Germany, ⁶Berlin-Brandenburg Center of Regenerative Therapies (BCRT), Berlin, Germany
Background/Purpose Interleukin- 4 (IL-4), a Th2-cell released immunomodulatory factor, has potent chondroprotective and anti-inflammatory properties able to inhibit the synthesis of IL-1β and TNFα, and…
Abstract Number: 937 • 2014 ACR/ARHP Annual Meeting
A Unique Role for IL-18 Receptor-α in Monocyte Migration in RA and K/BxN Serum Transfer Arthritis
W. Alexander Stinson¹, Phillip L. Campbell¹, Jeffrey Ruth², Gautam Edhayan², Ray A. Ohara², Nicholas Lepore³, Alisa E. Koch⁴, David A. Fox² and M. Asif Amin², ¹Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, ²Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, ³University of Michigan, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, ⁴Department of Veteran's Affairs and University of Michigan, Ann Arbor, MI
Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by monocyte (MN) recruitment. Proinflammatory cytokines and their corresponding receptors play an important role in…
Abstract Number: 400 • 2014 ACR/ARHP Annual Meeting
Clinical Utility of 14-3-3η in the Evaluation of Inflammatory Arthritis
Lance Feller¹, Paul Tuttle IV² and Terry L. Moore³, ¹Rheumatology, Saint Louis University, St. Louis, MO, ²Rheumatology, Saint Louis University, Saint Louis, MO, ³Internal Medicine/Rheumatology, Saint Louis University, Saint Louis, MO
Background/Purpose 14-3-3 proteins are chaperonins found in all eukaryotic cells. There are multiple isoforms which are thought to be involved in intracellular signaling and transcription…
Abstract Number: 415 • 2014 ACR/ARHP Annual Meeting
a Dual-Center, Double Blind Randomized Study for a New Scientific Approach in Assessment of Tender Joints in Inflammatory Arthritis Using the Smart Joint Assessor Glove Device (Smart JAG Device)
Mohammad Khan¹, Larry Willis², Swapan Nath³, Cheryl Guest², Lindsey Gillispie⁴ and Mary Jane Rorick⁴, ¹Arthritis & Rheumatology Center of Oklahoma, Oklahoma City, OK, ²Research, Arthritis & Rheumatology Center of Oklahoma, PLLC, Oklahoma City, OK, ³Department of Pediatrics and Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁴Rheumatology, McBride Orthopedic Hospital, Oklahoma City, OK
Background/Purpose Tender Joint Count (TJC) is a vital quality measure to assess the progression of Inflammatory Arthritis both from a therapeutic and a diagnostic standpoint.…

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