Abstracts tagged "inflammatory arthritis"

Abstract Number: 1245 • 2017 ACR/ARHP Annual Meeting
Transition in Work Status and Quality of Life in People with Inflammatory Arthritis
Wiebke Bartels¹, Eric C. Sayre², Pam Rogers³ and Diane Lacaille⁴, ¹Science, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada, ³Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, ⁴University of British Columbia, Arthritis Research Canada, Richmond, BC, Canada
Background/Purpose: People with inflammatory arthritis (IA) frequently have to stop working due to their arthritis. It is assumed that economic and psychosocial consequences of premature…
Abstract Number: 107 • 2017 Pediatric Rheumatology Symposium
Children with Relapsing Polychondritis are likely to be seen in the emergency room prior to establishing the diagnosis
Marcela Ferrada¹, Ninet Sinaii², Keith A. Sikora³, Peter C. Grayson⁴, Thomas Christie⁵, Robert Colbert⁴ and James D. Katz⁶, ¹NIAMS, National Institues of Health, Bethesda, MD, ²Clinical Center, National Institutes of Health, Bethesda, MD, ³Pediatric Translational Research Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁵Relapsing Polychondritis Awareness and Support Foundation, Anoka, MN, ⁶NIAMS, National Institutes of Health, Bethesda, MD
Background/Purpose: Relapsing polychondritis (RP) is a rare immune-mediated disease characterized by recurrent episodes of chondritis. The pathogenesis of RP is poorly understood, and clinical manifestations…
Abstract Number: 463 • 2016 ACR/ARHP Annual Meeting
Deficiency of Transmembrane Protein VISTA (V-domain Immunoglobulin Suppressor of T-cell Activation) Ameliorates Murine Collagen-II Antibody-Induced Arthritis
Roy Fava^1,2, Sabrina Ceeraz³, Susan Eszterhas⁴, Petra Sergent³, Christopher Burns⁵ and Mathew Vincenti^6,7, ¹Research, Department of Veterans Affairs, White River Junction, VT, ²Department of Medicinee, Geisel School of Medicine at Dartmouth, Lebanon, NH, ³Microbiology/Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, ⁴Research, Department of Veterans Affairs, white River Junction, VT, ⁵Section of Rheumatology, Geisel School of Medicine at Dartmouth, Lebanon, NH, ⁶Department of Veterans Affairs, White River Junction, VT, ⁷Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH
Background/Purpose: The transmembrane protein VISTA, is a member of the B7/CD28 family of immune modulator proteins and can function as a negative immune checkpoint regulator…
Abstract Number: 486 • 2016 ACR/ARHP Annual Meeting
IRF5 Promotes Arthritis but Restricts Virus Replication and Spread during Chikungunya Virus Infection
Jonathan Miner¹, Amber Smith², Raeann Shimak² and Michael Diamond³, ¹Internal Medicine / Rheumatology, Washington University in Saint Louis School of Medicine, Saint Louis, MO, ²Washington University in Saint Louis School of Medicine, Saint Louis, MO, ³Medicine / Infectious Diseases, Washington University in Saint Louis School of Medicine, Saint Louis, MO
Background/Purpose: Chikungunya virus (CHIKV) is an arthritogenic alphavirus that invades the joints and causes chronic arthritis in up to 60% of infected individuals. Over the…
Abstract Number: 726 • 2016 ACR/ARHP Annual Meeting
Comparison of Infliximab Immunogenicity in Inflammatory Arthritis Versus Inflammatory Bowel Disease Patients in Routine Clinical Practice
Marianne Guirgis¹, Melanie Favre dit Jeanfavre², Charles Benaim³, Matthieu Perreau⁴, Pierre Michetti⁵, Michel Maillard¹ and Pascal Zufferey⁶, ¹gastroenterology, Lausanne, Switzerland, ²DAL, RHU, Lausanne, Switzerland, ³DAL, MPR, Lausanne, Switzerland, ⁴Medecine /CHUV, Immunology, Lausanne, Switzerland, ⁵La Source-Beaulieu, Lausanne, Switzerland, ⁶Rhu /Dal .Chuv, Rheumatology, Lausanne, Switzerland
Background/Purpose: Infliximab is a biological agent frequently used for inflammatory arthritis (IA) such as spondyloarthritis, rheumatoid arthritis, psoriatic arthritis as well as for the inflammatory…
Abstract Number: 917 • 2016 ACR/ARHP Annual Meeting
B Cells Inhibit Osteoblast Differentiation in Inflammatory Arthritis
Wen Sun^1,2, Nida Meednu³, Alex Rosenberg¹, Javier Rangel-Moreno⁴, Victor Wang³, Teresa Owen¹, Hengwei Zhang⁵, Brendan Boyce¹, Jennifer H. Anolik¹ and Lianping Xing¹, ¹University of Rochester Medical Center, Rochester, NY, ²Nanjing Medical University, Nanjing, China, ³Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁴Allergy, Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is frequently associated with bone loss due to imbalanced bone resorption and formation. B cell depletion therapy (BCDT) attenuates bone erosion…
Abstract Number: 992 • 2016 ACR/ARHP Annual Meeting
The Impact of Inflammatory Arthritis (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, reactive arthritis) on Maternal and Neonatal Outcomes: A Population-Level Analysis
Stephanie Keeling¹, Anamaria Savu² and Padmaja Kaul³, ¹Department of Medicine, Division of Rheumatology, Edmonton, AB, Canada, ²Canadian Vigour Center, Edmonton, AB, Canada, ³Cardiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The impact of inflammatory arthritis (IA) including rheumatoid (RA), psoriatic (PsA), and spondyloarthritis (SpA) on maternal, obstetrical and neonatal outcomes is not well described…
Abstract Number: 1033 • 2016 ACR/ARHP Annual Meeting
Targeting Notch-Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis
Wen Sun^1,2, Hengwei Zhang³, Hua Wang^1,2, Yahui Grace Chiu⁴, Christopher T. Ritchlin⁵, Amy Kiernan¹, Brendan Boyce¹ and Lianping Xing¹, ¹University of Rochester Medical Center, Rochester, NY, ²Nanjing Medical University, Nanjing, China, ³Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, ⁴Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Increased expression of Notch signaling molecules has been reported in synovial samples of patients with rheumatoid arthritis (RA). However, the identity of the cell…
Abstract Number: 1341 • 2016 ACR/ARHP Annual Meeting
Rheumatic and Musculoskeletal Immune-Related Adverse Events Due to Immune Checkpoint Inhibitors: A Systematic Literature Review
Laura Cappelli¹, Anna Kristina Gutierrez², Ami A. Shah³ and Clifton Bingham III⁴, ¹Medicine/Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Johns Hopkins University, Baltimore, MD
Rheumatic and Musculoskeletal Immune-Related Adverse Events due to Immune Checkpoint Inhibitors: A Systematic Literature Review Background/Purpose: Immune checkpoint inhibitors (ICI) are effective treatments for advanced…
Abstract Number: 1517 • 2016 ACR/ARHP Annual Meeting
Does Inflammatory Arthritis Really Improve during Pregnancy? a Systematic Review and Meta-Analysis
Hannah Jethwa¹, Suzanne Lam², Colette Smith³ and Ian Giles⁴, ¹General Medicine, Wexham Park Hospital, London, United Kingdom, ²Croyden University Hospital, London, United Kingdom, ³Statistics, Royal Free Hospital Foundation Trust, London, United Kingdom, ⁴Centre for Rheumatology, University College London, Centre for Rheumatology, University College London, London, United Kingdom
Background/Purpose: Disease activity is considered to improve in approximately 75% of patients with rheumatoid arthritis (RA) during pregnancy. This figure, however, is derived from…
Abstract Number: 2337 • 2016 ACR/ARHP Annual Meeting
Sleep Quality, Disturbances and Physical Activity: A Nationwide Survey Among Health Professionals on Their Engagement with Irish People Who Have Rheumatic Disease
Sean McKenna¹, Alan Donnelly², Sandy Fraser³ and Norelee Kennedy¹, ¹Department of Clinical Therapies, University of Limerick, Ireland, Limerick, Ireland, ²Department of Physical Education and Sports Sciences, University of Limerick, Ireland, Limerick, Ireland, ³Department of Rheumatology, University Hospitals Limerick, Ireland, Limerick, Ireland
Background/Purpose: Sleep disturbance is common in people who have inflammatory arthritis and can contribute to disability, symptomatology, and use of increased healthcare. Disturbed sleep is…
Abstract Number: 3251 • 2016 ACR/ARHP Annual Meeting
Sleep and Physical Activity: A Nationwide Survey Among People with Rheumatic Disease in Ireland
Sean McKenna¹, Alan Donnelly², Sandy Fraser³ and Norelee Kennedy¹, ¹Department of Clinical Therapies, University of Limerick, Ireland, Limerick, Ireland, ²Department of Physical Education and Sports Sciences, University of Limerick, Ireland, Limerick, Ireland, ³Department of Rheumatology, University Hospitals Limerick, Ireland, Limerick, Ireland
Background/Purpose: Sleep is an important aspect in maintaining the body’s circadian rhythm and plays an important role in maintaining health. Disrupted or lower levels…
Abstract Number: 19 • 2016 ACR/ARHP Annual Meeting
Tumour Necrosis Factor Inhibition Is Associated with Weight Gain in Patients with Inflammatory Arthritis
Peter Wong¹, Alison Bowling², Cheryl Tulk³, Di Freeman³ and Hanish Bagga³, ¹Mid-North Coast Arthritis Clinic and University of New South Wales Rural Clinical School, Coffs Harbour, Australia, ²School of Health and Human Sciences, Southern Cross University, Coffs Harbour, Australia, ³Mid-North Coast Arthritis Clinic, Coffs Harbour, Australia
Background/Purpose: Targeted blockade of tumour necrosis factor (TNF) has been a major therapeutic advance in the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA) and…
Abstract Number: 25 • 2016 ACR/ARHP Annual Meeting
Have Outcomes of Patients with Inflammatory Arthritis Improved in the New Millennium? a Comparison of the 10 Year Outcome in Cohorts Recruited in 1990-4 and 2000-4
James Gwinnutt¹, Deborah P.M. Symmons^1,2, Alex J Macgregor^3,4, Jacqueline Chipping^3,4, Tarnya Marshall^3,4, Mark Lunt¹ and Suzanne M.M. Verstappen¹, ¹Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom, ³Rheumatology, Norfolk and Norwich University Hospital, Norwich, United Kingdom, ⁴School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, United Kingdom
Background/Purpose: New treatments have improved the short term outlook for patients with inflammatory polyarthritis (IP) over the past 20 years. However there is limited evidence…
Abstract Number: 101 • 2016 ACR/ARHP Annual Meeting
Rheumatology Care Utilization and Geographic Distance from Rheumatology Sites within the United States Veteran Affairs Health Care System
Jessica A. Walsh¹, Zachary Burningham², Chia-Chen Teng, MS³, Daniel O. Clegg⁴ and Brian C. Sauer, PhD³, ¹University of Utah School of Medicine, Salt Lake City, UT, ²SLC Veterans Affairs Medical Center, SLC IDEAS Center, Salt Lake City, UT, ³Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁴Division of Rheumatology, University of Utah Medical Center, Salt Lake City, UT
Background/Purpose: Within the Veteran Affairs (VA) health care system, there are often large geographic distances between patients and rheumatology providers. The purpose of this study…

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