Abstracts tagged "Imaging"

Abstract Number: 1136 • ACR Convergence 2025
The Impact of Iron Overload and HFE Genetic Mutations on Joint Disease in Haemochromatosis: Data from the Haemochromatosis Arthropathy Inception Cohorts
Bayram Farisogullari¹, Pedro Machado², Stephanie Finzel³, Graeme Carroll⁴, Geraldine mcCarthy⁵, John Stack⁶, Simone Parisi⁷, Graca Porto⁸, richette pascal⁹, Gyorgy Nagy¹⁰, Marton Weidl¹⁰, Ann Rosenthal¹¹, Pascal Guggenbuhl¹², Katarzyna Banaszkiewicz¹³, Barbara Butzeck¹⁴, Howard Don¹⁵, Svenja Engelhardt¹⁶, Jeremy Shearman¹⁷, David Mitchell¹⁸, Jane Barker¹⁹, Valerie Brueton¹⁹, Philip Coathup¹⁹, Jacquie Dowsett¹⁹, Marie Duncan¹⁹, Tracey Dunleavy¹⁹, Ian Fish¹⁹, Allin Hoggarth¹⁹, Mark McKinnon¹⁹, James Minter¹⁹, Tim Osborne¹⁹, Marguerite Smith¹⁹, Christine Wright¹⁹ and Patrick Kiely²⁰, ¹University College London, London, ²Department of Rheumatology, University College London, and Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS Trust, Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, ³Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ⁴Fiona Stanley Hospital, Perth, Western Australia, Australia, ⁵Mater Misericordiae University Hospital, Dublin, Ireland, ⁶Mater Misericordiae University Hospital, Dublin, Dublin, Ireland, ⁷Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Turin, Italy, ⁸Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal, ⁹Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, ¹⁰Buda Hospital of the Hospitaller Order of Saint John of God, Budapest, Hungary, ¹¹Department of Medicine, Division of Rheumatology, Medical College of Wisconsin, Wisconsin, ¹²Rennes University Hospital, Rennes, France, ¹³University Clinical Center in Gdańsk, Smoluchowskiego ¹⁷ Street, ⁸⁰-⁹⁵² Gdańsk, Poland., Gdańsk, Poland, ¹⁴European Federation of Associations of Patients with Haemochromatosis,, Croissy-sur-Seine, France, ¹⁵Haemochromatosis International, Barnstaple, United Kingdom, ¹⁶University of Freiburg, Freiburg im Breisgau, Germany, ¹⁷South Warwickshire University Foundation Trust and Warwick Medical School,, Warwick, United Kingdom, ¹⁸Clongriffin Medical Centre, Dublin, Ireland, ¹⁹c/o St George's University Hospitals NHS Trust, London, United Kingdom, ²⁰St George's University Hospitals NHS Foundation Trust, London, United Kingdom
Background/Purpose: A EULAR task force developed classification criteria (CC) for Haemochromatosis Arthropathy (HA) using a cohort of people with the C282Y homozygous mutation and arthropathy…
Abstract Number: 0507 • ACR Convergence 2025
Diagnostic performance of the lacrimal and salivary gland ultrasound in patients with primary Sjogren’s disease of recent onset versus sicca controls.
Rosa Elena Cervantes¹, Carina Soto-Fajardo², Fabian Carranza³, Gabriela Hernandez-Molina⁴, Narlly Ruíz Quintero⁵, Daniela Rojas Abarca⁶, Ana Mora⁷, Ada Rocío Morales Meza⁶, Carlos Montiel Castañeda⁸, Angela Maldonado Luna⁹, Fabiola Sánchez Zamudio⁶ and Carlos Pineda², ¹National Institute of Rehabilitation "Luis Guillermo Ibarra Ibarra"", Mexico City, Distrito Federal, Mexico, ²National Rehabilitation Institute " Luis Guillermo Ibarra Ibarra ", Mexico City, Mexico, ³National Rehabilitation Institute " Luis Guillermo Ibarra Ibarra ", Ciudad de México, Mexico, ⁴Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Federal District, Mexico, ⁵Instituto Nacional de Ciencias Medicas y Nutricion, México, city, Distrito Federal, Mexico, ⁶National Institute of Rehabilitation "Luis Guillermo Ibarra Ibarra", Mexico, City, Distrito Federal, Mexico, ⁷National Rehabilitation Institute " Luis Guillermo Ibarra Ibarra ", Mexico, Mexico, ⁸National Institute of Rehabilitation "Luis Guillermo Ibarra Ibarra", México, city, Distrito Federal, Mexico, ⁹Instituto Nacional de Ciencias Medicas y Nutricion, Mexico, City, Estado de México, Mexico
Background/Purpose: Sjögren's disease (SjD) is a chronic systemic autoimmune disease primarily affecting the exocrine glands. There is an increasing use of salivary gland ultrasound in…
Abstract Number: 2470 • ACR Convergence 2025
Impaired Myocardial Flow Reserve on 82-Rubidium Positron Emission Tomography in Patients with Systemic Sclerosis
Attila Feher¹, Morgan Emokpae², Bindu Koyi², Ibolya Csecs², Baran Gunes³, Albert Sinusas² and Monique Hinchcliff⁴, ¹Yale University School of Medicine - New Haven, CT, New Haven, CT, ²Yale School of Medicine, New Haven, ³Yale University School of Medicine, Pompton Plains, NJ, ⁴Yale School of Medicine, Westport, CT
Background/Purpose: Cardiovascular death ranks as the second leading cause of mortality related to systemic sclerosis (SSc), with coronary microvascular dysfunction (CMVD) likely contributing to this…
Abstract Number: 1967 • ACR Convergence 2025
Developing an Algorithm to Quantify Dermatomyositis-Associated Calcinosis Using Infrared Imaging
Saahil Sachdeva¹, Briana Cervantes², Lisa Rider³ and Adam Schiffenbauer⁴, ¹NIEHS/NIBIB/NIH, Danville, CA, ²Department of Emergency Medicine, Norfolk, VA, ³National Institute of Environmental Health Sciences/National Institutes of Health, Environmental Autoimmunity Group, Bethesda, MD, ⁴National Institute of Health/National Institute of Dental and Craniofacial Research, Bethesda, MD
Background/Purpose: Dermatomyositis (DM) is a rare autoimmune disease characterized by chronic muscle and skin inflammation. One potential complication of DM is calcinosis, the heterotopic calcification…
Abstract Number: 1941 • ACR Convergence 2025
How Calculating Consensus Change Scores Can Go Wrong: Lessons from Multi-reader Imaging Assessments in Axial Spondyloarthritis
Ana Bento da Silva¹, Sofia Ramiro², Floris A. van Gaalen¹, Robert Landewé³, Miranda van Lunteren¹, Liese de Bruin¹, Gizem Ayan⁴, Xenofon Baraliakos⁵, Monique Reijnierse⁶, Jürgen Braun⁷, Désirée Van Der Heijde¹ and Manouk de Hooge⁸, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Bunde, Netherlands, ³Department of Rheumatology, Amsterdam University Medical Center, Amsterdam, Netherlands; and Zuyderland Medical Center, Heerlen, Netherlands, ⁴Ankara Research and Training Hospital, Ankara, Turkey, ⁵Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁶Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁷Ruhr-University, Bochum, Germany; and Rheumatologische Versorgungszentrum (RVZ) Steglitz, Berlin, Germany, ⁸Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Background/Purpose: In research, imaging findings are often assessed by multiple readers and individual readers’ scores are combined into aggregate scores to determine the presence of…
Abstract Number: 1580 • ACR Convergence 2025
Lung vasculature quantification on computed tomography predicts new onset of interstitial lung disease in systemic sclerosis
Maria Iacovantuono¹, Nicholas landini², lisa Jungblut³, Gesa Sauer⁴, Rucsandra Dobrota⁵, Sinziana Muraru⁶, Muriel Elhai⁷, Carina Mihai⁸, Mike Becker⁹, Maria Sole Chimenti¹⁰, Thomas Frauenfelder³, Anna-Maria Hoffmann-Vold¹¹, Oliver Distler¹² and Cosimo Bruni¹³, ¹Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy. Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Spinete, Italy, ²Department of Radiological Sciences, Oncology and Pathology, "Sapienza" University, Policlinico Umberto I, Rome, Italy. Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Rueil Malmaison, France, ³Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, University Zurich, Zurich, Switzerland, zurich, Switzerland, ⁴Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, zurich, Switzerland, ⁵Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, the LOOP Zurich, Zurich, Switzerland, ⁶University of Zurich, University Hospital Zurich, Zürich, Switzerland, ⁷University Hospital zurich, Zürich, Switzerland, ⁸University Hospital Zurich, University of Zurich, Zurich, Switzerland, ⁹Dept. of Rheumatology, University Hospital Zurich, Zürich, Switzerland, ¹⁰Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, Tor Vergata University, Rome, Italy, Roma, Italy, ¹¹Oslo University Hospital, Oslo, Norway, ¹²Department of Rheumatology, University Hospital Zurich, University of Zurich, Switzerland, Zurich, Switzerland, ¹³Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Background/Purpose: Interstitial lung disease (ILD) is highly prevalent in systemic sclerosis (SSc) and a leading cause of mortality. Recent studies have identified clinical risk factors…
Abstract Number: 1126 • ACR Convergence 2025
Clinical Impact of Signs of Calcium Pyrophosphate Deposition Disease (CPPD) on Radiographs of Hands and Wrists in a Real-World Cohort of Patients with Early Rheumatoid Arthritis
Coralie Tremblay¹, Nathalie Carrier², Hugues Allard-Chamard³, Javier Marrugo⁴, Sophie Roux⁴, Gilles Boire⁵ and Ariel Masetto⁴, ¹Université de Sherbrooke, Division of Rheumatology, Department of Medicine and Health Sciences, Sherbrooke, Canada, and Centre intégré universitaire de santé et de services sociaux de l’Estrie – Centre hospitalier universitaire de Sherbrooke (CIUSSS de l’Estrie – CHUS), Sherbrooke, Canada, Saint-Augustin-de-Desmaures, QC, Canada, ²Centre integré universitaire de santé et de services sociaux de l’Estrie – Centre hospitalier universitaire de Sherbrooke (CIUSSS de l’Estrie-CHUS), Sherbrooke, Canada, ³Université de Sherbrooke, Sherbrooke, Canada, ⁴Université de Sherbrooke, Division of Rheumatology, Department of Medicine and Health Sciences, Sherbrooke, Canada, and Centre intégré universitaire de santé et de services sociaux de l’Estrie – Centre hospitalier universitaire de Sherbrooke (CIUSSS de l’Estrie – CHUS), Sherbrooke, Canada, Sherbrooke, Canada, ⁵Retired, Sherbrooke, QC, Canada
Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is a common cause of arthropathy over the age of 60. It can also manifest as a chronic polyarticular…
Abstract Number: 0428 • ACR Convergence 2025
The OMERACT Juvenile Idiopathic Arthritis MRI Score for Active and Structural Lesions in the Sacroiliac Joints: Development and Validation in Two Longitudinal Cohorts
Walter P. Maksymowych¹, Michael Francavilla², Nele Herregods³, Robert G. W. Lambert⁴, Arthur Meyers⁵, Joel Paschke⁶, Jennifer Stimec⁷, Pamela Weiss⁸ and Dax Rumsey⁹, ¹Department of Medicine, University of Alberta, ⁵⁶⁸ Heritage Building, Edmonton, AB, Canada, ²Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, ³Department of Pediatric Radiology, Ghent University Hospital, Ghent, Belgium, ⁴University of Alberta, Department of Radiology & Diagnostic Imaging, Edmonton, AB, Canada, ⁵Department of Radiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ⁶CARE Arthritis Limited, Edmonton, AB, Canada, ⁷Department of Diagnostic Imaging, SickKids, University of Toronto, Toronto, Canada, ⁸Childrens Hospital of Philadelphia, Philadelphia, PA, ⁹Department of Pediatrics, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The OMERACT Juvenile Idiopathic Arthritis MRI (JAMRIS) Working group has defined a spectrum of MRI lesions in the sacroiliac joint (SIJ) in youth with…
Abstract Number: 2431 • ACR Convergence 2025
Bone marrow- activity on 18F-FDG PET/CT as a Predictor of Hematologic Manifestations in Systemic Lupus Erythematosus
Sungwon Ko¹, Young-Eun Kim¹, Soyoon Yoon², Soo Min Ahn¹, Ji Seon Oh¹, Yong-Gil Kim¹, Chang-Keun Lee³, Bin Yoo¹, Dong Yun Lee⁴ and Seokchan Hong¹, ¹Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, Seoul, Republic of Korea, ²Department of Nuclear Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea, ³Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Seoul, Republic of Korea, ⁴Department of Nuclear Medicine, University of Ulsan College of Medicine, Seoul, Seoul, Republic of Korea
Background/Purpose: Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is a noninvasive imaging modality widely used to assess inflammatory activity in various autoimmune and hematologic…
Abstract Number: 1966 • ACR Convergence 2025
Assessing the Impact of Cutaneous Melanin on Microvascular Oxygenation Measurement in Systemic Sclerosis Using Multispectral Imaging
Rosie Barnes¹, Joanne Manning², Graham Dinsdale³, Ariane Herrick⁴, Mark Dickinson⁵ and Andrea Murray⁶, ¹University of Manchester, Manchester, England, United Kingdom, ²Northern Care Alliance NHS Foundation Trust, Salford, United Kingdom, ³Northern Care Alliance, Salford, United Kingdom, ⁴The University of Manchester, UK, Aberdeen, United Kingdom, ⁵The University of Manchester, Manchester, ⁶University of Manchester, Salford, United Kingdom
Background/Purpose: Microvascular abnormalities, leading to hypoxia, drive the SSc disease process. Accurate measurement of skin oxygenation, both baseline and during ‘stress’/reperfusion (which can be mimicked…
Abstract Number: 1939 • ACR Convergence 2025
Salivary Gland Ultrasounds Can Be Read by General Radiologists: A Review Of 4 Years of Reports from an Urban Academic Radiology Department
Ali Dhanaliwala and Dana DiRenzo, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Salivary gland ultrasound (SGUS) has the potential to inform diagnosis and progression of Sjogren’s disease, a systemic autoimmune disease which results in progressive inflammation…
Abstract Number: 1572 • ACR Convergence 2025
Compromised intracellular oxygen availability and severe mitochondrial dysfunction in the skeletal muscle of patients with systemic sclerosis
Gwenael Layec¹, Tracy Frech² and Anthony Donato³, ¹University of Nebraska, Omaha, NE, ²Vanderbilt University Medical Center, Nashville, TN, ³Salt Lake Veterans Affairs Medical Center, Salt Lake City, UT
Background/Purpose: Muscle weakness and fatigue are frequent manifestations associated with systemic sclerosis (SSc). However, significant gaps remain in our understanding of the effects of SSc…
Abstract Number: 0962 • ACR Convergence 2025
Spatial Proteomics Analysis of the organization of tertiary lymphoid structures in Systemic Sclerosis Skin
Dennis Bleck¹, Karen Drechsel², Tim Filla³, Yi-Nan Li⁴, Andrea-Hermina Györfi⁵, Alexandru-Emil Matei⁶ and Jörg Distler⁷, ¹University Hospital Düsseldorf, Department of Rheumatology, Hiller Research Center, Düsseldorf, Nordrhein-Westfalen, Germany, ²University Hospital Düsseldorf, Department of Rheumatology, Hiller Research center, Düsseldorf, Nordrhein-Westfalen, Germany, ³Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University., Düsseldorf, Germany, ⁴University Hospital of Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany, ⁵Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University., Düsseldorf, Germany, ⁶Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Hiller Research Center, University Hospital Düsseldorf, Medical Faculty of Heinrich-Heine University. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany, Düsseldorf, Germany, ⁷University Hospital Duesseldorf and HHU, Duesseldorf, Germany
Background/Purpose: Systemic Sclerosis (SSc) is a rare autoimmune connective tissue disease and presents a significant medical challenge. It is characterized by fibrotic tissue remodeling, along…
Abstract Number: 0419 • ACR Convergence 2025
Ultrasound-Guided Synovial Biopsy in Children and Adolescents with Juvenile Arthritis: Initial Results
Patricia Vega-Fernandez¹, Kelly Rogers², Megan Quinlan-Waters³, Sheila Angeles-Han², Alexei Grom¹, Daniel Lovell¹, Jennifer Huggins⁴, Ekemini Ogbu¹, Amy Cassedy⁵, Sara Szabo¹, Tracy Ting¹, Grant Schulert¹, McKenzie Vater⁶, Hermine Brunner¹, Jackeline Rodriguez-Smith¹ and Katelyn Banschbach⁷, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Cincinnati Children's Hospital, Cincinnati, OH, ³Cincinnati Children's Hospital Medical Center, CCHMC, ⁴Cincinnati Children's Medical Center, Cincinnati, OH, ⁵Cincinnati Children's hospital medical center, cincinnati, OH, ⁶Cincinnati Children's Hospital Medical Center, Fort Thomas, KY, ⁷cincinnati Children's hospital, Villa Hills, KY
Background/Purpose: Ultrasound-guided synovial biopsy (USGSB) has been recently implemented for clinical and research purposes in adults with inflammatory arthritis. The current use of USGSB in…
Abstract Number: 2325 • ACR Convergence 2025
Association of Galectin-3 and Myocardial Dysfunction in Patients with Psoriatic Arthritis
Natalia Guajardo-Jauregui¹, Iris J. Colunga-Pedraza², Dionicio A. Galarza-Delgado², Jose R Azpiri-Lopez³, Jesus Alberto Cardenas-de la Garza⁴, Diana E. Flores-Alvarado⁵ and Rosa Arvizu-Rivera⁶, ¹Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Mexico, ²Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ³Cardiology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ⁴Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, ⁵Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Nuevo Leon, Mexico, ⁶Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Nuevo León, Mexico
Background/Purpose: Psoriatic arthritis (PsA) is an immune-mediated condition associated with an increased risk of cardiovascular (CV) events due to disease-specific characteristics. Galectin-3 (Gal-3) is a…

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