Abstracts tagged "Imaging"

Abstract Number: 1684 • 2013 ACR/ARHP Annual Meeting
Early Combination Immunosuppression and Serial Non-Invasive Imaging Improves Outcome In Takayasu Arteritis
Taryn Youngstein¹, Michael Quinn¹, James Peters¹ and Justin C. Mason², ¹Rheumatology Unit, Hammersmith Hospital, Imperial College London, London, United Kingdom, ²Rheumatology and Vascular Sciences, Hammersmith Hospital, Imperial College London, London, United Kingdom
Background/Purpose: Takayasu arteritis (TA) affects the aorta and its branches, pre-disposing to stenoses and aneurysmal dilatation. While morbidity remains high, evidence for efficacy of immunosuppressive…
Abstract Number: 1517 • 2013 ACR/ARHP Annual Meeting
Different Imaging Abnormalities Suggestive Of Spondyloarthritis Are Present In Early Axial Spondyloarthritis. Data From The DESIR Cohort
Anna Moltó¹, Simon Paternotte², Désirée van der Heijde³, Pascal Claudepierre⁴, Martin Rudwaleit⁵ and Maxime Dougados⁶, ¹Cochin Hospital, Paris- Descartes University, Paris, France, ²Rheumatology Department, Paris- Descartes University, Cochin hospital, Paris, France, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Paris-Est University; LIC EA4393; APHP, Henri Mondor Hospital, Creteil, France, ⁵Endokrinologikum, Berlin, Germany, ⁶Université Paris René Descartes and Hôpital Cochin, Paris, France
Background/Purpose: Patients can fulfil the ASAS (Assessment of SpondyloArthritiS) sets of criteria with either objective evidence of sacroiliac joint damage (X-Ray) or inflammation (MRI) (“imaging”…
Abstract Number: 1159 • 2013 ACR/ARHP Annual Meeting
Exercise Suppresses Systemic Inflammation Via Inhibition Of NF-κB Activation In Monocytes
Alisa Blazek¹, Derrick Knapik², Lai-Chu Wu³, Nicholas A. Young³, Wael N. Jarjour⁴ and Sudha Agarwal⁵, ¹Molecular, Cellular and Developmental Biology, The Ohio State University, Columbus, OH, ²College of Medicine, The Ohio State University, Columbus, OH, ³Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁴Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Division of Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: Inflammation is integral to joint damage and bone erosion in rheumatoid arthritis. We reported previously that physiologic levels of exercise are anti-inflammatory and suppress local…
Abstract Number: 1134 • 2013 ACR/ARHP Annual Meeting
More Evidence For Breaking The ‘law Of valgus’: Imaging Evidence For Higher Prevalence and Volume Of Bone Marrow Lesions In The Medial Patellofemoral Joint
Charles Ratzlaff¹ and Jeffrey W. Duryea², ¹Harvard Medical School / Brigham and Women's Hospital, Boston, MA, ²Radiology, Brigham and Women's Hospital, Boston, MA
Background/Purpose : We recently developed an efficient semi-automated measure of tibial and femoral BML volume and validated it against the Whole-Organ Magnetic Resonance Imaging Score…
Abstract Number: 1128 • 2013 ACR/ARHP Annual Meeting
Validation Of a Rapid, Quantitative Method Of Magnetic Resonance Imaging-Detected Osteoarthritis-Related Bone Marrow Lesions In The Patellofemoral Joint
Charles Ratzlaff¹ and Jeffrey W. Duryea², ¹Harvard Medical School / Brigham and Women's Hospital, Boston, MA, ²Dept of Radiology, Brigham & Women, Boston, MA
Background/Purpose : We recently developed an efficient semi-automated measure of tibial and femoral BML volume and validated it against the Whole-Organ Magnetic Resonance Imaging Score…
Abstract Number: 1112 • 2013 ACR/ARHP Annual Meeting
Examining Phenotypes Of Patients With Psoriasis In The Prepare Study For Similarities Between Diagnosed Psoriatic Arthritis and Those With Signs Of Subclinical Psoriatic Arthritis Detected By Imaging
Philip Mease¹, Javier Coindreau², Lotus Mallbris², Annette Szumski³ and Heather Jones², ¹Division of Rheumatology Research, Swedish Medical Center and University of Washington, Seattle, WA, ²Pfizer Inc., Collegeville, PA, ³Specialty Care, Pfizer Inc., Collegeville, PA
Background/Purpose: Progression of psoriatic arthritis (PsA) has traditionally been evaluated using clinical assessments. However, a strong relationship between clinical and radiological outcomes has been shown,…
Abstract Number: 1086 • 2013 ACR/ARHP Annual Meeting
The Straight Neck in Fibromyalgia
Robert S. Katz¹ and Anthony Farkasch², ¹Rush Medical College, Chicago, IL, ²Rheumatology Associates, Chicago, IL
Background/Purpose: In patients with fibromyalgia a straight neck is based on calculating the Cobb angle, a standard radiographic measurement, of lateral view radiographs of the…
Abstract Number: 2889 • 2013 ACR/ARHP Annual Meeting
Bone Marrow Edema and Structural Lesions In The Sacroiliac Joint In a Large Cohort Of Patients With Axial Spondyloarthritis, Chronic Low Back Pain and Healthy Controls
L. van Hoeven^1,2, J.J. Luime², P.D.M. de Buck³, J.M.W. Hazes² and A.E.a.M. Weel⁴, ¹Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, MC Haaglanden, Den Haag, Netherlands, ⁴Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands
Background/Purpose: MRI of the sacroiliac joint (SIJ) is included in the ASAS classification criteria for axial spondyloarthritis (axSpA) to identify patients at an earlier stage of…
Abstract Number: 863 • 2013 ACR/ARHP Annual Meeting
Romosozumab Administration Is Associated With Significant Improvements In Lumbar Spine and Hip Volumetric Bone Mineral Density and Content Compared With Teriparatide
H K Genant¹, S Boonen², M A Bolognese³, C Mautalen⁴, J P Brown⁵, C Recknor⁶, S Goemaere⁷, K Engelke⁸, Y-C Yang⁹, M Austin⁹, A Grauer⁹ and C Libanati⁹, ¹UCSF & Synarc Inc., San Francisco, CA, ²Leuven University Division of Geriatric Medicine, Leuven, Belgium, ³The Bethesda Health Research Center, Bethesda, MD, ⁴Centro de Osteopatias Medicas, Buenos Aires, Argentina, ⁵CHU de Québec Research Centre and Laval University, Québec, QC, Canada, ⁶United Osteoporosis Centers, Gainesville, GA, ⁷Ghent University Hospital, Ghent, Belgium, ⁸Synarc Germany, Hamburg, Germany, ⁹Amgen Inc., Thousand Oaks, CA
Background/Purpose: Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. Romosozumab, a monoclonal antibody to sclerostin stimulates bone formation and decreases bone resorption. In a phase…
Abstract Number: 2820 • 2013 ACR/ARHP Annual Meeting
Disease-Regulated Local Interleukin-10 Gene Therapy Diminishes Synovitis and Articular Cartilage Damage In Experimental Arthritis
Eline A. Vermeij¹, Mathijs G.A. Broeren¹, Miranda B. Bennink¹, Onno J. Arntz², Inger Gjertsson³, Wim B. van den Berg¹ and Fons A.J. van de Loo¹, ¹Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden, Gothenburg, Sweden
Background/Purpose: Rheumatoid arthritis (RA) is a chronic destructive autoimmune disease and in most patients the disease follows an intermittent course with periods of exacerbation and…
Abstract Number: 615 • 2013 ACR/ARHP Annual Meeting
Relationship Between 25-Hydroxyvitamin D [25(OH)D] and Risk For Cardiovascular Events In Systemic Lupus Erythematosus Over 11 Years In An Inception Cohort
Apinya Lertratanakul¹, Peggy Wu², Alan Dyer¹, Dafna D. Gladman³, Murray B. Urowitz³, Paul R. Fortin⁴, Dominique Ibanez³, Rosalind Ramsey-Goldman⁵ and for the Systemic Lupus International Collaborating Clinics (SLICC)⁶, ¹Northwestern University, Chicago, IL, ²Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Medicine, Centre de Recherche du Chu de Québec et Université Laval, Quebec City, QC, Canada, ⁵Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Toronto Western Hospital, Division of Rheumatology, University of Toronto, Toronto Western Hospital (Coordinating Center), Toronto, ON, Canada
Background/Purpose: 25(OH)D deficiency has been associated with increased cardiovascular disease (CVD) in the general population. We investigated the relationship between 25(OH)D and CVD events in…
Abstract Number: 2801 • 2013 ACR/ARHP Annual Meeting
Comparative Longitudinal Analysis Of Periarticular Bone Structure In Patients Treated With Methotrexate In Combination Of Either TNF Blockers Or Tocilizumab
Sebastian Kraus¹, Matthias Englbrecht¹, Juergen Rech², Roland Kocijan¹, Georg A. Schett¹ and Stephanie Finzel¹, ¹Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Inhibition of tumor necrosis factor alpha (TNFi) and interleukin-6 receptor (IL6Ri, tocilzumab) are among the most potent therapeutic strategies in patients with rheumatoid arthritis…
Abstract Number: 307 • 2013 ACR/ARHP Annual Meeting
Abnormal Imaging and Increased Osteoclast Precursors In a Psoriasis Cohort Are Associated with New Onset of Psoriatic Arthritis
Ralf G. Thiele¹, Yahui Grace Chiu¹, Francisco A. Tausk², Bethany A. Marston¹, Gregory Dieudonne³, Vaseem Chengazi³, Michelle Smith¹, Sharon Moorehead¹, Rick Barrett¹ and Christopher T. Ritchlin¹, ¹Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ²Dermatology, University of Rochester, Rochester, NY, ³Radiology, University of Rochester, Rochester, NY
Background/Purpose: Psoriasis (Ps) precedes joint inflammation by about 10 years in patients who develop psoriatic arthritis (PsA). Several studies have documented abnormal musculoskeletal imaging findings…

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