Abstracts tagged "Imaging"

Abstract Number: 3255 • 2015 ACR/ARHP Annual Meeting
Brain White Matter Integrity: A Future Biomarker for Rheumatoid Arthritis Related Fatigue?
Neil Basu¹, Marayam Alsyedalhashem², Mariella D'Allesandro³, Alison D. Murray², Daniel J. Clauw⁴ and Gordon D. Waiter², ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ³Muscloskeletal Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Fatigue is a major burden among patients with rheumatoid arthritis (RA). The identification of reliable biomarkers would greatly enhance research in this challenging field. …
Abstract Number: 1336 • 2015 ACR/ARHP Annual Meeting
To PET or Not to PET in General Rheumatology Practice
Kavina Shah, Roshni Doshi, Joshua Balogun-Lynch, Henry Penn and Shahir Hamdulay, Rheumatology, Northwick Park Hospital, Middlesex, United Kingdom
Background/Purpose: Fluoro-deoxy-glucose positron emission tomography with computerised tomography (PET/CT) is an imaging modality which identifies tissues with high metabolic activity. It is used in the…
Abstract Number: 1375 • 2015 ACR/ARHP Annual Meeting
S100A8/A9, a Serum and Imaging Biomarker for Assessing Joint Inflammation and Destruction in Experimental Seronegative Arthritis
Edwin J. W. Geven¹, Shahla Abdolahi-Roodsaz¹, Annet Sloetjes¹, Marije I. Koenders¹, Dirk Föll², Johannes Roth³, Thomas Vogl³ and Peter L. E. M. van Lent¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, ³Institute of Immunology, University of Münster, Münster, Germany
Background/Purpose: Seronegative joint diseases such as psoriatic arthritis and juvenile idiopathic arthritis are characterized by the lack of autoantibodies, potent biomarkers used for predicting disease…
Abstract Number: 1381 • 2015 ACR/ARHP Annual Meeting
The Relationship Between Serum Cholinesterase, Number of Organ Involvement and Fibrotic Markers in Japanese Patients with IgG4-Related Disease
Hirofumi Nishikawa¹, Yoshinori Taniguchi¹, Yoshiko Shimamura¹, Kosuke Inoue¹, Taro Horino¹, Susumu Nishiyama², Yasuhiko Yoshinaga² and Yoshio Terada¹, ¹Kochi University, Nankoku, Japan, ²Kurashiki Medical Center, Kurashiki, Japan
Background/Purpose: To evaluate the relationship between cholinesterase, number of organ involvement and serum fibrotic markers in Japanese patients with IgG4-related disease (IgG4-RD). Methods: The clinical…
Abstract Number: 1445 • 2015 ACR/ARHP Annual Meeting
Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis
Yongdong Zhao¹, Fatma Dedeoglu², Polly J. Ferguson³, Sivia Lapidus⁴, Ronald Laxer⁵, Suzanne C. Li⁶ and for the CARRA SVRD subcommittee, ¹Pediatric Rheumatology, Seattle Children's Hospital, Seattle, WA, ²Rheumatology, Boston Children's Hospital, Boston, MA, ³Dept of Pediatrics--Rheum, University of Iowa, Iowa City, IA, ⁴Pediatric Rheumatology, Goryeb Children's Hospital, Morristown, NJ, ⁵Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁶Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ
Background/Purpose: Chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), is an autoinflammatory bone disease of unknown cause that can result in…
Abstract Number: 1505 • 2015 ACR/ARHP Annual Meeting
Carotid Artery Atherosclerosis in Patients with Active Rheumatoid Arthritis: Predictors of Plaque Occurrence and Progression over 24 Weeks
Tatiana Nevskaya¹, Janet E. Pope², Lillian Barra³ and Grace Parraga⁴, ¹Medicine, Division of Rheumatology, University of Western Ontario, London, ON, Canada, ²University of Western Ontario, London, ON, Canada, ³Medicine, Division of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ⁴University of Western Ontario, Robarts Research Institute, London, ON, Canada
Background/Purpose: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). Methods: Carotid arteries of RA patients were scanned…
Abstract Number: 1595 • 2015 ACR/ARHP Annual Meeting
Impaired Coronary Flow Reserve in Rheumatoid Arthritis: A Robust Indicator of Cardiac Structure Associated with Systemic Inflammation and Rheumatoid Arthritis Treatments
Isabelle Amigues¹, Jon T. Giles¹, Sabahat Bokhari², Afshin Zartoshti³, Richard Weinberg², Cesare Russo⁴ and Joan Bathon³, ¹Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Cardiology, Columbia University Medical Center, NY, NY, ³Rheumatology, Columbia University Medical Center, NY, NY, ⁴Division of Cardiology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Myocardial microvascular dysfunction may precede or coexist with coronary atherosclerosis and heart failure, two conditions over-represented in RA. Coronary flow reserve (CFR) offers an…
Abstract Number: 1576 • 2014 ACR/ARHP Annual Meeting
Reversal of Damage in Psoriatic Arthritis
Amir Haddad¹, Ker-Ai Lee², Arane Thavaneswaran¹, Vinod Chandran¹, Richard J. Cook² and Dafna D. Gladman¹, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada
Background/Purpose Psoriatic arthritis could lead to severe damage and disability. However, cases of improvement in joint damage over time have been reported in the literature.…
Abstract Number: 1405 • 2014 ACR/ARHP Annual Meeting
Five-Year Changes in Myocardial Structure and Function in Patients with Rheumatoid Arthritis
John M. Davis III¹, Grace Lin², Jae Oh³, Cynthia S. Crowson⁴, Terry M. Therneau⁵, Eric L. Matteson¹ and Sherine E. Gabriel⁶, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Cardiology, Mayo Clinic, Rochester, MN, ³Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research, Mayo Clinic, Rochester, MN, ⁵Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁶Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Patients with rheumatoid arthritis (RA) suffer an increased risk of heart failure not explained by traditional cardiovascular risk factors. Previously, we have shown…
Abstract Number: 1204 • 2014 ACR/ARHP Annual Meeting
Oral Administration of Nano-Emulsion Curcumin in Mice Suppresses Inflammatory-Induced NFkB Signaling and Macrophage Migration
Nicholas A. Young¹, Michael Bruss², Mark Gardner³, William Willis³, Xiaokui Mo³, Giancarlo Valiente³, Yu Cao⁴, Zhongfa Liu⁴, Lai-Chu Wu¹ and Wael N. Jarjour⁵, ¹Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ²Division of Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, ³Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁴Rheumatology and Immunology, The Ohio State University Wexner Medical Center, columbus, OH, ⁵Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: The major obstacles to successful use of curcumin as an anti-inflammatory agent are its low solubility in water and rapid metabolism, which both translate…
Abstract Number: 2995 • 2014 ACR/ARHP Annual Meeting
Surrogate Measures of Extent of Interstitial Lung Disease As Measured By Quantitative Radiographic Analysis in Patients with Systemic Sclerosis
Elizabeth Volkmann¹, Donald Tashkin², Chi-hong Tseng¹, Kim Hyun³, Jonathan Goldin³, Philip J. Clements⁴, Daniel E. Furst¹, Dinesh Khanna⁵, Eric Kleerup¹, Michael Roth¹ and Robert Elashoff⁶, ¹Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ²Medicine, University of California at Los Angeles, Los Angeles, CA, ³Radiology, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ⁴University of California, Los Angeles, Department of Medicine, Los Angeles, CA, ⁵University of Michigan Health System, Ann Arbor, MI, ⁶Biomathematics, University of California, Los Angeles, Los Angeles, CA
Background/Purpose: Extent of systemic sclerosis (SSc)-related interstitial lung disease (ILD) predicts disease course, mortality and treatment response. While quantitative analyses of total extent of ILD…
Abstract Number: 1190 • 2014 ACR/ARHP Annual Meeting
Osteoarthritis-like Changes Are Present in the Tibia and Femur 1 Year Following ACL Reconstruction
Valentina Pedoia¹, Drew A. Lansdown², Musa Zaid³, Charles McCulloch⁴, C. Benjamin Ma² and Xiaojuan Li⁵, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ²Department of Orthopedic Surgery, UCSF, San Francisco, CA, ³Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁴Department of Epidemiology and Biostatistics, San Francisco, CA, ⁵Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose Statistical Shape Modeling (SSM) is a promising tool that has the ability to characterize complex shapes in a brief feature vector. The application of…
Abstract Number: 2930 • 2014 ACR/ARHP Annual Meeting
Precisely Quantified Fibrosis in Labial Salivary Glands Predicts Sjögren’s Syndrome Classification in a Multiple Regression Model
Kerry M. Leehan^1,2, Michael Brown¹, Courtney Montgomery¹, Astrid Rasmussen¹, David M. Lewis³, Lida Radfar⁴, Donald U. Stone⁵, Stephen Young³, R. Hal Scofield^1,6, Kathy L. Sivils^1,2 and A. Darise Farris^2,7, ¹Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³College of Dentistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁴College of Dentristry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁵Department of Ophthalmology, Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁶Department of Endocrinology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁷Arthritis and Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Primary Sjögren's Syndrome (pSS) is a systemic, progressive autoimmune exocrinopathy that presents diagnostic challenges. Focal lymphocytic infiltrates in labial salivary gland (SG) biopsies, serum…
Abstract Number: 1184 • 2014 ACR/ARHP Annual Meeting
Subclinical Inflammation in Psoriatic Patients with No History of Psoriatic Arthritis: An Assessment By Magnetic Resonance Imaging
David Simon¹, Francesca Faustini¹, Matthias Englbrecht¹, Arnd Kleyer¹, Roland Kocijan², Judith Haschka³, Sebastian Kraus³, Axel J. Hueber¹, Michael Sticherling⁴, Georg Schett¹ and Jürgen Rech³, ¹Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, ²Medical Department II, St. Vincent Hospital, Vienna, Austria, ³Internal Medicine 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁴Department of Dermatology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose Six to 39% of patients with cutaneous psoriasis (PSO) can develop psoriatic arthritis (PsA). The transition from skin disease to joint involvement is only…
Abstract Number: 2772 • 2014 ACR/ARHP Annual Meeting
The Use of Imaging in the Diagnosis of Polymyalgia Rheumatica: Systematic Literature Review and Meta-Analysis
Sarah Mackie¹, Gouri Koduri², Catherine L. Hill^3,4, Andrew Hutchings⁵, Richard J. Wakefield⁶, Bhaskar Dasgupta⁷ and Jeremy Wyatt⁸, ¹NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ²Rheumatology, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, ³Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia, ⁴Discipline of Medicine, University of Adelaide, Adelaide, Australia, ⁵Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁶NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Department of Rheumatology, Southend University Hospital, Essex, United Kingdom, ⁸Leeds Insitute of Health Sciences, University of Leeds, Leeds, United Kingdom
Background/Purpose ACR/EULAR provisional classification criteria for polymyalgia rheumatica (PMR) incorporate musculoskeletal ultrasound of shoulder and hip (bursitis and synovitis given equal weight). Our objective was…

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