Abstracts tagged "Imaging"

Abstract Number: 162 • 2015 ACR/ARHP Annual Meeting
Ultrasonography Versus Clinical Examination in Early DMARD-Naïve Rheumatoid Arthritis – a Comparative Study of Synovitis on the Individual Joint Level
Lena B. Nordberg¹, Elisabeth Lie¹, Siri Lillegraven¹, Anna-Birgitte Aga¹, Inge C Olsen², Hilde Berner Hammer³, Till Uhlig⁴, Désirée van der Heijde⁵, Tore K. Kvien¹, Espen A. Haavardsholm¹ and the ARCTIC Study Group, ¹Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Diakonhjemmet Hospital, Oslo, Norway, ⁵Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Ultrasonography (US) is increasingly accepted as an important tool in diagnosis and management of rheumatoid arthritis (RA). However, it is not well known to…
Abstract Number: 1693 • 2015 ACR/ARHP Annual Meeting
High Prevalence of Cardiac Disease in Patients with Ankylosing Spondylitis
Sjoerd C. Heslinga¹, Thelma C. Konings², Otto Kamp², Mike J.L. Peters³, Yvo M. Smulders³, Irene E. Van der Horst - Bruinsma¹ and Mike T. Nurmohamed¹, ¹Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, ²Cardiology, VU University Medical Center, Amsterdam, Netherlands, ³Internal Medicine, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Ankylosing spondylitis (AS) is associated with increased risk of concomitant cardiac disease, such as valvular regurgitation, conduction disturbances and decreased ventricular function (1). However,…
Abstract Number: 188 • 2015 ACR/ARHP Annual Meeting
Whole-Body Synovial Uptake of a 99mtc-Labelled RGD Peptide Is Highly Correlated with Power Doppler Ultrasound
Toby Garrood¹, Matthew Morrison², Dharsha Shivapatham³, Khaldoun Chaabo¹, Fahim Ul-Hassan⁴, Jim Ballinger⁴, Gary Cook⁵ and Andrew P. Cope⁶, ¹Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ²GE Healthcare, Amersham, United Kingdom, ³Department of Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ⁴Nuclear Medicine, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ⁵Imaging Sciences, Kings College London, London, United Kingdom, ⁶Academic Department of Rheumatology, King´s College London, London, United Kingdom
Background/Purpose: Musculoskeletal ultrasound, and specifically power Doppler ultrasound (PDUS), is more sensitive than clinical examination for the assessment of active synovitis in patients with rheumatoid…
Abstract Number: 1767 • 2015 ACR/ARHP Annual Meeting
Noninvasive Assessment of Macrophage Activation in Experimental Glomerulonephritis Using Optical Imaging with Near-Infrared Light Serves As a Surrogate of Disease Activity
Sebastian Braehler¹, Dongyue Huang², Matthew Cheung², Walter Akers³ and Alfred Kim², ¹Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO, ²Rheumatology, Washington University School of Medicine, Saint Louis, MO, ³Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO
Background/Purpose: Glomerulonephritis (GN) represents a major cause of morbidity & mortality. The standard for diagnosing GN is through renal biopsy, but this is not performed…
Abstract Number: 189 • 2015 ACR/ARHP Annual Meeting
Indocyanine Green (ICG) -Enhanced Fluorescence Optical Imaging (FOI) in Patients with Active Rheumatoid Arthritis; A Comparative Study with Ultrasound and Association with Biomarkers
Shin-ya Kawashiri^1,2, Ayako Nishino³, Masataka Umeda³, Shoichi Fukui¹, Yoshikazu Nakashima³, Naoki Iwamoto¹, Kunihiro Ichinose¹, Hideki Nakamura¹, Tomoki Origuchi⁴, Kiyoshi Aoyagi² and Atsushi Kawakami³, ¹Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Department of Immunology and Rheumatology, Nagasaki University, Nagasaki, Japan, ⁴Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Methods: Twenty-five active RA patients (mean disease durations 7.5 years and DAS28-ESR 5.90) who fulfilled 2010 RA classification criteria were consecutively enrolled in this study.…
Abstract Number: 1892 • 2015 ACR/ARHP Annual Meeting
Impact of Cardiac Magnetic Resonance Imaging with T1 Mapping and Multi-b Value Diffusion-Weighted Sequences in Systemic Sclerosis for the Assessment of Myocardial Microscopic Fibrosis and Perfusion
Benjamin Terrier¹, Hervé Gouya², Alice Berezne¹, Alexis Regent³, Pascal Cohen¹, Loïc Guillevin⁴, Claire Le Jeunne⁵, Paul Legmann², Olivier Vignaux⁶ and Luc Mouthon⁷, ¹Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Paris, France, ²AP-HP Cochin Hospital, Department of Radiology B, Paris, France, ³Service de médecine interne, Hôpital Cochin, Paris, France, ⁴Internal Medicine, Hopital Cochin, Paris, France, ⁵Department of Internal Medicine, Hotel-Dieu Hospital, AP-HP, Paris, Paris, France, ⁶Radiology, Cochin University Hospital, Paris, France, ⁷Department of Internal Medicine, Department of Internal Medicine, Cochin Hospital, Referent Center for Necrotizing Vasculitis and Systemic Sclerosis, Paris-Descartes University, AP-HP, Paris, France
Background/Purpose: Systemic sclerosis (SSc) is a complex disease associating vasculopathy, cutaneous and visceral fibrosis, and autoimmunity. Myocardial microscopic fibrosis may occur and potentially lead to…
Abstract Number: 848 • 2015 ACR/ARHP Annual Meeting
Nitroglycerin Patch Application in Systemic Sclerosis: Evaluation By Laser Doppler Imaging
Georgiana Bentea, Aurelien Wauters, Jean-Claude Wautrecht and Elie Cogan, Erasme Hospital, Brussels, Belgium
Background/Purpose: Systemic sclerosis (SSc) is a complex autoimmune disease, commonly associated with Raynaud phenomenon (RP). The aim of this study was to characterize the microvascular…
Abstract Number: 1970 • 2015 ACR/ARHP Annual Meeting
Incidence and Predictors of Thoracic Aortic Damage in Biopsy-Proven Giant Cell Arteritis: A Single-Institution Cohort Study
Matthew J. Koster¹, Cristian Labarca², Cynthia S. Crowson³, Eric L. Matteson¹ and Kenneth J. Warrington¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Rheumatology, Clinica Alemana Universidad del Desarrollo, Santiago, Chile, ³Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: Patients with giant cell arteritis (GCA) are at an increased risk for aortic structural damage; however, the timing and predisposing characteristics for development of…
Abstract Number: 928 • 2015 ACR/ARHP Annual Meeting
The Value of Early Ultrasound-Detected Osteophytes in Hand Osteoarthritis: Predicting the Future
Alexander Mathiessen¹, Barbara Slatkowsky-Christensen², Tore K. Kvien³, Ida K. Haugen⁴ and Hilde Berner Hammer², ¹Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴P.O. Box 23, Diakonhjemmet Hospital, Vinderen, Norway
Background/Purpose: Ultrasound is more sensitive than conventional radiographs in detecting small osteophytes in hand osteoarthritis (OA). Osteophytes can be seen prior to joint space narrowing…
Abstract Number: 2027 • 2015 ACR/ARHP Annual Meeting
Development of a Dual Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout
Sara Bayat¹, Opetaia Aati², Juergen Rech¹, Alexander Cavallaro³, Michael Lell³, Elizabeth Araujo⁴, Christina Petsch⁴, Lisa K. Stamp⁵, Georg A. Schett⁶, Bernhard Manger¹ and Nicola Dalbeth², ¹Department of Internal Medicine 3, Rheumatology & Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³Department of Radiology, University of Erlangen-Nuremberg, Department of Radiology, Erlangen, Germany, ⁴Medical Department 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Medicine, University of Otago, Christchurch, Christchurch, New Zealand, ⁶University of Erlangen-Nuremberg, Erlangen, Germany
Development of a Dual Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout Background/Purpose: Dual energy computed tomography (DECT) can visualize urate…
Abstract Number: 1299 • 2015 ACR/ARHP Annual Meeting
Can Bone Marrow Lesions be Scored More Reliably and Responsively in Knee Osteoarthritis Using a Web-Based Overlay System (KIMRISS) Than By Standard MRI Osteoarthritis Knee Scoring (MOAKS)? Data from the Osteoarthritis Initiative and a Prospective Trial of Adaluminab Therapy
Jacob Jaremko¹, Mark Buller², Dean Jeffery², David McDougall³, Benjamin Smith², Robert G Lambert¹ and Walter Maksymowych⁴, ¹Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ²Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesions (BML) relate to pain and prognosis in knee osteoarthritis. The Knee Inflammation MRI Scoring System (KIMRISS) offers simple template-assisted binary BML…
Abstract Number: 2093 • 2015 ACR/ARHP Annual Meeting
Are General and Central Adiposity Associated with MRI-Assessed Structural Changes in the Knees of Older Adults?
Tomoko Fujii¹, Iva Miljkovic¹, Robert M. Boudreau², Ali Guermazi³, Sara R. Piva⁴, Elsa S. Strotmeyer², Laura Carbone⁵, Tamara B. Harris⁶, Elisa A. Marques⁶, M Kyla Shea⁷, Michael C. Nevitt⁸, Anne B. Newman² and C Kent Kwoh⁹, ¹University of Pittsburgh, Pittsburgh, PA, ²Epidemiology, University of Pittsburgh, Pittsburgh, PA, ³Department of Radiology, Boston University School of Medicine, Boston, MA, ⁴Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ⁵Rheumatology, Georgia Regents University, Augusta, GA, ⁶National Institute on Aging, Bethesda, MD, ⁷Tuffs University, Boston, MA, ⁸Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁹University of Arizona, Tucson, AZ
Background/Purpose: Obesity is one of the few modifiable risk factors of knee osteoarthritis (OA). However, it is not established whether a mechanical or metabolic mechanism…
Abstract Number: 1314 • 2015 ACR/ARHP Annual Meeting
Quantitative MRI Measurement of Tenosynovitis Demonstrates Differing Responses of Synovitis and Tenosynovitis after RA Treatment
Michael A. Bowes¹, Gwenael Guillard¹, Graham R. Vincent², Jane E. Freeston³, Edward M. Vital⁴, Paul Emery⁵ and Philip G. Conaghan⁶, ¹Imorphics, Manchester, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³LIMM Section of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds Gen Infirmary, Leeds, United Kingdom, ⁶University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom
Background/Purpose: Inflammation of the tendon sheaths (tenosynovitis) is a recognised component of rheumatoid arthritis (RA). A comprehensive assessment of inflammation will require the inclusion of…
Abstract Number: 2110 • 2015 ACR/ARHP Annual Meeting
Imaging and Safety Assessments Following Treatment with Febuxostat and Placebo for 2 Years in Subjects with Early Gout
Nicola Dalbeth¹, Kenneth G. Saag², William Palmer³, Hyon Choi³, Barbara Hunt⁴, Patricia MacDonald⁴, Ulrich Thienel⁴ and Lhanoo Gunawardhana⁴, ¹Department of Medicine, University of Auckland, Auckland, New Zealand, ²Div Clinical Immun & Rheum, University of Alabama at Birmingham, Birmingham, AL, ³Massachusetts General Hospital/Harvard Medical School, Boston, MA, ⁴Takeda Pharmaceuticals International, Deerfield, IL
Background/Purpose: No clinical trials had previously investigated the characteristics of joint damage in early gout or the benefit of instituting urate-lowering therapy (ULT) earlier in…
Abstract Number: 1317 • 2015 ACR/ARHP Annual Meeting
Clinical Utility of Joint Space Width and X-Ray Radiogrammetry in RA: Markers for Early Radiographic Progression
Michael Platten¹, Yogan Kisten², Johan Kälvesten³, Kristina Forslind⁴ and Ronald F. van Vollenhoven⁵, ¹Medicine, Karolinska Institutet, Huddinge, Sweden, ²ClinTRID, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ³Sectra AB, Stockholm, Sweden, ⁴Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden, ⁵Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden
Background/Purpose: Early prediction of radiographic progression is beneficial in rheumatoid arthritis (RA) patient management. The van der Heijde modified Sharp score (SHS) is currently the…

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