Abstracts tagged "Imaging"

Abstract Number: 1444 • 2016 ACR/ARHP Annual Meeting
Differential Expression of Wnt Inhibitors before and after Joint Inflammation Onset in Rat Arthritis Could Partly Explain Paradoxical Effect of Sclerostin Inhibition
Guillaume Courbon¹, Raphaelle Lamarque², Marie-Thérèse Linossier², Norbert Laroche², Thierry Thomas³, Laurence Vico² and Hubert Marotte³, ¹SAINBIOSE INSERM U1059, University of Lyon, Saint-Etienne, France, ²SAINBIOSE INSERM U1059, University of Lyon, Saint Etienne, France, ³SAINBIOSE INSERM U1059 and Rheumatology department, University of Lyon and University Hospital of Saint Etienne, Saint Etienne, France
Background/Purpose: Periarticular bone loss in rheumatoid arthritis is considered to be mainly related to synovial inflammation, leading to uncoupling between decreased bone formation and increased…
Abstract Number: 257 • 2016 ACR/ARHP Annual Meeting
CNS Manifestations of Patients with Muckle-Wells Syndrome
sara Sebnem KILIC¹, sukru cekic² and Juan Aróstegui³, ¹Pedaitric Rheumatology, Prof Dr, Bursa, Turkey, ²Dr, Bursa, Turkey, ³Prof, Barcelona, Spain
Background/Purpose: CAPS is a rare autoinflammatory disease associated with mutations in the NLRP3 gene that result in overactivation of the inflammasome, increased secretion of IL-1beta…
Abstract Number: 1577 • 2016 ACR/ARHP Annual Meeting
An Investigation of Translocator Protein As a Tissue and Peripheral Blood Biomarker of Inflammation in Rheumatoid Arthritis
Nehal Narayan¹, Francesco Carlucci² and Peter C. Taylor³, ¹Rheumatology, University of Oxford, Oxford, United Kingdom, ²The Botnar Research Centre, University of Oxford, oxford, United Kingdom, ³Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom
Background/Purpose: Translocator protein (TSPO) is a mitochondrial cholesterol transporter, utilised in diseases as a Positron Emission Tomography (PET) imaging marker of macrophage infiltration. Recent observations…
Abstract Number: 678 • 2016 ACR/ARHP Annual Meeting
Additional Information from CT or MRI Imaging Can Increase Rheumatologists’ Consensus on Grading Sacroiliitis By Radiography: Results of the Trimage Project
Nigil Haroon¹, Xenofon Baraliakos², Anne Grethe Jurik³, Gercek Can⁴, Ali Balcı⁵, Muhammet Cinar⁶, Ediz Dalkilic⁷, Salim Donmez⁸, Omer Nuri Pamuk⁹, Yavuz Pehlivan¹⁰, Salih Pay¹¹, Handan Yarkan¹², Gokce Kenar¹³ and Nurullah Akkoc¹³, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ³Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁴Department of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ⁵Radiology, Dokuz Eylul University, Izmir, Turkey, ⁶Division of Rheumatology, Gülhane Military Medical Academy, School of Medicine, Ankara, Turkey, ⁷Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey, ⁸Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, ⁹Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, ¹⁰Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, ¹¹Rheumatology, Yüksek Ihtisas University, Special Koru Hospital, Ankara, Turkey, ¹²Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, ¹³Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey
Background/Purpose: The diagnosis of ankylosing spondylitis (AS) is anchored on definitive changes of sacroiliits by radiography. This is relevant not only to clinical diagnosis, but…
Abstract Number: 1720 • 2016 ACR/ARHP Annual Meeting
Predictive Value of Different Tools for Detection of Psoriatic Arthritis in Patients with Psoriasis in Daily Routine Care Using Questionnaires for Diagnosis of Psoriatic Arthritis and Fluorescence-Optical Imaging Technique
Michaela Koehm¹, Tanja Rossmanith², Hans-Eckhard Langer³, GR Burmester⁴, Siegfried Wassenberg⁵, Benjamin Köhler⁶, Ulrich Kaesser⁷, Marina Backhaus⁸, Harald Burkhardt⁹ and Frank Behrens⁹, ¹Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt/Main, Germany, ²Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine & Pharmacology TMP, Frankfurt, Germany, ³RHIO (Rheumatology, Immunology, Osteology) Duesseldorf, Duesseldorf, Germany, ⁴Charité – University Medicine Berlin, Berlin, Germany, ⁵Rheumazentrum, Ratingen, Germany, ⁶Rheumazentrum Ratingen, Ratingen, Germany, ⁷6Internistische Praxisgemeinschaft am Krankenhaus Balserische Stiftung Gießen, Gießen, Germany, ⁸Rheumatology, Park-Klinik Weissensee, Berlin, Germany, ⁹Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt, Germany
Background/Purpose: Psoriasis (Pso) is one of the most common chronic inflammatory skin disease in Europe. Psoriatic arthritis (PsA) is closely associated to Pso; the skin…
Abstract Number: 863 • 2016 ACR/ARHP Annual Meeting
Arterial Lesions in Giant Cell Arteritis
Tanaz A. Kermani¹, Sehriban Diab², Antoine Sreih³, David Cuthbertson⁴, Renee Borchin⁵, Simon Carette⁶, Lindsy J. Forbess⁷, Gary S. Hoffman⁸, Curry L. Koening⁹, Carol A. McAlear¹⁰, Paul A. Monach¹¹, Larry W. Moreland¹², Christian Pagnoux¹³, Philip Seo¹⁴, Robert F. Spiera¹⁵, Kenneth J. Warrington¹⁶, Steven R. Ytterberg¹⁷, Carol A. Langford¹⁸, Nader A. Khalidi¹⁹ and Peter A. Merkel²⁰, ¹Rheumatology, University of California Los Angeles, Santa Monica, CA, ²St. Joseph’s Healthcare, McMaster University, Hamilton, ON, Canada, ³Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, ⁴Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, ⁵University of South Florida, Tampa, FL, ⁶Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁷Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁸Rheumatic & Immunologic Dis, Cleveland Clinic Foundation, Cleveland, OH, ⁹Rheumatology, University of Utah, Salt Lake City, UT, ¹⁰University of Pennsylvania, Philadelphia, PA, ¹¹Rheumatology, Boston University School of Medicine, Boston, MA, ¹²Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹³Division of Rheumatology, Mount Sinai Hospital, University Health Network, University of Toronto, Toronto, Canada, Toronto, ON, Canada, ¹⁴Medicine, Johns Hopkins University, Baltimore, MD, ¹⁵Hospital for Special Surgery, Cornell, New York, NY, ¹⁶Rheumatology, University of California Los Angeles, CA, USA Mayo, Rochester, MN, ¹⁷Rheumatology, Mayo Clinic, Rochester, MN, ¹⁸Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ¹⁹Division of Rheumatology, St. Joseph’s Health Care, McMaster University, Hamilton, ON, Canada, ²⁰Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: This study aimed to describe large arterial lesions among patients with giant cell arteritis (GCA) and to understand what clinical characteristics are associated…
Abstract Number: 2293 • 2016 ACR/ARHP Annual Meeting
Cardiometabolic Risk and Subclinical Urate Deposits in Patients with Symptomatic Hyperuricemia and Metabolic Syndrome
Seoyoung C. Kim¹, Rajesh Garg², Stacy Smith³, Alyssa Wohlfahrt⁴, Anarosa Campos⁵, Kathleen Vanni⁴, Lauren K Lee⁶, Penny Wang⁶, Zhi Yu⁷, Marcelo Di Carli⁸ and Daniel H. Solomon⁹, ¹Rheumatology, Immunology and Allergy; Pharmacoepidemiologyand Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ²Endocrinology, Brigham & Women's Hospital, Boston, MA, ³Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA, ⁸Div. of Nuclear Medicine, Brigham and Women's Hospital, Boston, MA, ⁹Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Elevated serum uric acid (sUA) levels, with and without gout, are associated with systemic inflammation, coronary artery disease (CAD), chronic kidney disease, and diabetes.…
Abstract Number: 875 • 2016 ACR/ARHP Annual Meeting
Pericardial Involvement in Biopsy-Proven Giant-Cell Arteritis (GCA) Patients Detected By CT Angiography (CTA): Prevalence at Diagnosis and Outcome with Glucocorticoid (GC) Treatment
Javier Marco-Hernández¹, Sergio Prieto-González², Rosa Gilabert³, Pedro Arguis⁴, Georgina Espígol-Frigolé⁵, Ana García-Martínez⁶, Ester Planas-Rigol⁵, Marc Corbera-Bellalta², Nekane Terrades-Garcia², Jose Hernández-Rodríguez² and Maria C. Cid⁷, ¹Internal Medicine, Hospital Clínic, Barcelona, Spain, ²Vasculitis Research Unit. Department of Autoimmune Diseases, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain, ³Center for Diagnostic Imaging, Hospital Clínic, Barcelona, Spain, ⁴Center for Diagnostic Imaging, Hospital Clínic. IDIBAPS. University of Barcelona, Barcelona, Spain, ⁵Department of Autoimmune and Systemic Diseases, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain, ⁶Emergeny Department, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain, ⁷Autoimmune and Systemic Diseases, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain
Background/Purpose: In GCA, cranial artery involvement is particularly frequent and underlies the classical manifestations and complications of the disease. Symptomatic pericarditis has been occasionally described…
Abstract Number: 3097 • 2016 ACR/ARHP Annual Meeting
Osteoclast Precursor Frequency and Imaging Findings Associated with Arthritis Onset in a Psoriasis Longitudinal Cohort
Ralf G. Thiele¹, Yahui Grace Chiu², Francisco Tausk³, Bethany A. Marston⁴, Changyong Feng⁵, Gregory Dieudonne⁶, Vaseem Chengazi⁶, Sharon Moorehead⁷, Debbie Campbell⁷ and Christopher T. Ritchlin⁸, ¹Medicine, University of Rochester Medical Center, Rochester, NY, ²Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, ³Dermatology, University of Rochester, Rochester, NY, ⁴Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Statistics, University of Rochester, Rochester, NY, ⁶Radiology, University of Rochester, Rochester, NY, ⁷Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY, ⁸Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Psoriasis (Ps) precedes joint inflammation by an average of 10 years psoriatic arthritis (PsA) patients. Reports have demonstrated abnormal musculoskeletal imaging findings in psoriasis…
Abstract Number: 892 • 2016 ACR/ARHP Annual Meeting
FDG-PET CT Evaluation By Visual Grading Is Not Sufficiently Discriminative to Assess Disease Activity in Takayasu’s Arteritis Patients with ‘Persistent’ Disease
Ali Ugur Unal¹, Fuat Dede², Tanju Yusuf Erdil², Tunc Ones², Fatma Alibaz-Oner³ and Haner Direskeneli⁴, ¹Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ²Department of Nuclear Medicine, Marmara University Faculty of Medicine, Istanbul, Turkey, ³Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Takayasu arteritis (TAK) is a large-vessel vasculitis in which assessment of disease activity is challenging. Recent studies support that 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed…
Abstract Number: 3133 • 2016 ACR/ARHP Annual Meeting
Association Between Quantitatively Measured Infrapatellar Fat Pad High Signal Intensity Alteration and Knee Structural and Symptomatic Abnormalities in Patients with Symptomatic Knee Osteoarthritis
WEIYU HAN¹, Graeme Jones² and Changhai Ding², ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: Infrapatellar fat pad (IPFP), a local adipose tissue, may have important contributions to knee osteoarthritis (OA). IPFP signal intensity alterations on MRI may represent…
Abstract Number: 928 • 2015 ACR/ARHP Annual Meeting
The Value of Early Ultrasound-Detected Osteophytes in Hand Osteoarthritis: Predicting the Future
Alexander Mathiessen¹, Barbara Slatkowsky-Christensen², Tore K. Kvien³, Ida K. Haugen⁴ and Hilde Berner Hammer², ¹Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴P.O. Box 23, Diakonhjemmet Hospital, Vinderen, Norway
Background/Purpose: Ultrasound is more sensitive than conventional radiographs in detecting small osteophytes in hand osteoarthritis (OA). Osteophytes can be seen prior to joint space narrowing…
Abstract Number: 2027 • 2015 ACR/ARHP Annual Meeting
Development of a Dual Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout
Sara Bayat¹, Opetaia Aati², Juergen Rech¹, Alexander Cavallaro³, Michael Lell³, Elizabeth Araujo⁴, Christina Petsch⁴, Lisa K. Stamp⁵, Georg A. Schett⁶, Bernhard Manger¹ and Nicola Dalbeth², ¹Department of Internal Medicine 3, Rheumatology & Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³Department of Radiology, University of Erlangen-Nuremberg, Department of Radiology, Erlangen, Germany, ⁴Medical Department 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Medicine, University of Otago, Christchurch, Christchurch, New Zealand, ⁶University of Erlangen-Nuremberg, Erlangen, Germany
Development of a Dual Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout Background/Purpose: Dual energy computed tomography (DECT) can visualize urate…
Abstract Number: 1299 • 2015 ACR/ARHP Annual Meeting
Can Bone Marrow Lesions be Scored More Reliably and Responsively in Knee Osteoarthritis Using a Web-Based Overlay System (KIMRISS) Than By Standard MRI Osteoarthritis Knee Scoring (MOAKS)? Data from the Osteoarthritis Initiative and a Prospective Trial of Adaluminab Therapy
Jacob Jaremko¹, Mark Buller², Dean Jeffery², David McDougall³, Benjamin Smith², Robert G Lambert¹ and Walter Maksymowych⁴, ¹Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ²Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesions (BML) relate to pain and prognosis in knee osteoarthritis. The Knee Inflammation MRI Scoring System (KIMRISS) offers simple template-assisted binary BML…
Abstract Number: 2093 • 2015 ACR/ARHP Annual Meeting
Are General and Central Adiposity Associated with MRI-Assessed Structural Changes in the Knees of Older Adults?
Tomoko Fujii¹, Iva Miljkovic¹, Robert M. Boudreau², Ali Guermazi³, Sara R. Piva⁴, Elsa S. Strotmeyer², Laura Carbone⁵, Tamara B. Harris⁶, Elisa A. Marques⁶, M Kyla Shea⁷, Michael C. Nevitt⁸, Anne B. Newman² and C Kent Kwoh⁹, ¹University of Pittsburgh, Pittsburgh, PA, ²Epidemiology, University of Pittsburgh, Pittsburgh, PA, ³Department of Radiology, Boston University School of Medicine, Boston, MA, ⁴Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ⁵Rheumatology, Georgia Regents University, Augusta, GA, ⁶National Institute on Aging, Bethesda, MD, ⁷Tuffs University, Boston, MA, ⁸Epidemiology and Biostatistics, UCSF, San Francisco, CA, ⁹University of Arizona, Tucson, AZ
Background/Purpose: Obesity is one of the few modifiable risk factors of knee osteoarthritis (OA). However, it is not established whether a mechanical or metabolic mechanism…

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