Abstracts tagged "Imaging"

Abstract Number: 934 • 2016 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging (MRI) Joint Space Narrowing Is an Independent Predictor of Radiographic and MRI Damage Progression in Patients with Early Rheumatoid Arthritis
Signe Møller-Bisgaard¹, Bo Jannik Ejbjerg², Iris Eshed³, Kim Hørslev-Petersen⁴, Merete Lund Hetland^5,6, Anne Grethe Jurik⁷, Henrik S Thomsen⁸, Trine Torfing⁹, Kristian Stengaard-Pedersen¹⁰, Peter Junker¹¹, Niels Steen Krogh¹², Tine Lottenburger¹³, Torkell Ellingsen¹⁴, Lis Smedegaard Andersen¹⁵, Henrik Skjødt¹⁶, Anders Svendsen¹⁴, Ulrik Tarp¹⁰, Ib Tønder Hansen¹⁰, Jan Pødenphant¹⁵, Jens Kristian Pedersen¹⁴, Hanne Lindegaard¹⁴, Aage Vestergaard¹⁷, Daniel Glinatsi¹⁶ and Mikkel Østergaard¹⁶, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ²Department of Rheumatology, Slagelse University Hospital, Slagelse, Denmark, ³Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, ⁴King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵Danish Rheumatologic Biobank and DANBIO registry, Rigshospitalet, Glostrup, Gentofte and Herlev University Hospital, Copenhagen, Denmark, ⁶Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark,, Copenhagen, Denmark, ⁷Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁸Department of Radiology, Herlev University Hospital, Copenhagen, Denmark, ⁹Department of Radiology, Odense University Hospital, Odense, Denmark, ¹⁰Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ¹¹University of Southern Denmark, Odense, Denmark, ¹²ZiteLab ApS, Copenhagen, Denmark, ¹³Department of Medicine, Vejle Regional Hospital, Vejle, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁵Department of Rheumatology, Gentofte University Hospital, Gentofte, Denmark, ¹⁶Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ¹⁷Department of Radiology, Hvidovre University Hospital, Denmark, Hvidovre, Denmark
Background/Purpose: Magnetic Resonance Imaging (MRI) osteitis and synovitis have been identified as predictors of structural damage progression in rheumatoid arthritis (RA)1,2, but the predictive value…
Abstract Number: 3177 • 2016 ACR/ARHP Annual Meeting
Targeted Nuclear Imaging for the Early Detection of Lung Involvement in Systemic Sclerosis
Janine Schniering¹, Stephanie Haller², Zhongning Guo¹, Martina Benesova^2,3, Carol A. Feghali-Bostwick⁴, Roger Schibli^2,3, Oliver Distler⁵, Cristina Müller^2,3 and Britta Maurer⁵, ¹Department of Rheumatology, University Hospital Zurich, Schlieren, Switzerland, ²Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen PSI, Switzerland, ³Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland, ⁴Medicine, Medical University of South Carolina, Charleston, SC, ⁵Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland
Background/Purpose: Interstitial lung disease (ILD) is one of the main causes of systemic sclerosis (SSc)-related deaths. Since routine diagnostics such as high resolution computed tomography…
Abstract Number: 1276 • 2016 ACR/ARHP Annual Meeting
Sensitive SPECT/CT Imaging of Fibroblast Activation Protein Expression after Anti-IL-22 Treatment in Experimental Arthritis
Debbie M. Roeleveld¹, Tessa van der Geest², Birgitte Walgreen¹, Monique M. Helsen¹, Tapan K. Nayak³, Christian Klein⁴, Martin Hegen⁵, Peter Laverman², Otto C. Boerman² and Marije I. Koenders¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Radiology & Nuclear Medicine, Radboud university medical center, Nijmegen, Netherlands, ³Research & Early development, Roche Pharmaceutical, Basel, Switzerland, ⁴Research & Early Development, Roche Pharmaceutical, Schlieren, Switzerland, ⁵Immunoscience Research Unit, Pfizer, Cambridge, MA
Background/Purpose: Rheumatoid arthritis (RA) synovial tissue has been demonstrated to express high levels of fibroblast activation protein (FAP) using anti-FAP-antibody 28H1. In addition, RA patients…
Abstract Number: 1279 • 2016 ACR/ARHP Annual Meeting
Imaging of Ankylosing Spondylitis By [18f]Fluoride PET-CT to Assess Bone Formation Activity and to Monitor Anti-TNF Therapy
Stefan Bruijnen¹, Nicki Verweij², Leonie van Duivenvoorde³, Dominique Baeten⁴, Christiaan van Denderen⁵, Joost Bot⁶, Otto Hoekstra⁷, Pieter Raijmakers⁶, Irene van der Horst - Bruinsma⁸ and Conny van der Laken², ¹Dept. of Rheumtaology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ²Dept. of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ³Amsterdam Rheumatology and immunology Center, Academic Medical Center, Amsterdam, Netherlands, ⁴Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, ⁵READE, Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, ⁶Department of Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, Netherlands, ⁷Nuclear medicine and PET research, VU University Medical Center, Amsterdam, Netherlands, ⁸Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands
Background/Purpose: Bone formation is an important hallmark of ankylosing spondylitis (AS). Recently, we demonstrated that axial bone formation activity in AS patients can be visualized…
Abstract Number: 1281 • 2016 ACR/ARHP Annual Meeting
Feasibility and Reliability of the Spondyloarthritis Research Consortium of Canada Sacroiliac Joint Inflammation Score for Children with Spondyloarthritis
Nancy A. Chauvin¹, Walter P. Maksymowych^2,3, Robert G. Lambert⁴, Jacob Jaremko⁵, David M. Biko¹, Timothy G. Brandon⁶, Joel Paschke² and Pamela F. Weiss^7,8, ¹Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ²CaRE Arthritis, Edmonton, AB, Canada, ³Medicine, University of Alberta, Edmonton, AB, Canada, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁷Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁸Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: We lack a method to quantify severity of inflammation in the pediatric sacroiliac joint. We evaluated the reliability and construct validity of the Spondyloarthritis…
Abstract Number: 1282 • 2016 ACR/ARHP Annual Meeting
Feasibility and Reliability of the Spondyloarthritis Research Consortium of Canada Sacroiliac Joint Structural Score for Children with Spondyloarthritis
Nancy A. Chauvin¹, Walter P. Maksymowych^2,3, Robert G. Lambert⁴, Jacob Jaremko⁵, David M. Biko¹, Timothy G. Brandon⁶, Joel Paschke³ and Pamela F. Weiss^7,8, ¹Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Medicine, University of Alberta, Edmonton, AB, Canada, ³CaRE Arthritis, Edmonton, AB, Canada, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁷Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁸Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: There is a critical need for measures to evaluate structural progression in the pediatric sacroiliac joint. We aimed to evaluate the precision and construct…
Abstract Number: 1288 • 2016 ACR/ARHP Annual Meeting
Evaluating Rheumatoid Arthritis Disease Activity Using Global Assessment of 18f-FDG Uptake in the Joints
William Raynor¹, Sara Alehashemi², Sina Houshmand³, Thomas J Werner³, Abass Alavi⁴ and Joshua Baker⁵, ¹University of Pennsylvania, Philadelphia, PA, ²Rheumatology, National Institutes of Health, Bethesda, MD, ³Radiology, University of Pennsylvania, Philadelphia, PA, ⁴Department of Radiology/Division of Nuclear Medicine, University of Pennsylvania, Philadelphia, PA, ⁵Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Clinical imaging modalities in rheumatoid arthritis (RA) such as MRI and ultrasound can detect morphologic changes associated with synovial inflammation. 18F-labeled fluorodeoxyglucose positron emission…
Abstract Number: 131 • 2016 ACR/ARHP Annual Meeting
Analysis of Correlation and Causes for Discrepancy Between Quantitative and Semi Quantitative Doppler Scores in Synovitis in Rheumatoid Arthritis
Hamed Rezaei^1,2,3, Erik af Klint⁴, Hilde B. Hammer⁵, Lene Terslev⁶, MA d'Agostino^7,8, Yogan Kisten³ and Laurent Arnaud⁹, ¹Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The rheumatology clinic of the Karolinska University Hospital, Stockholm, Sweden, ²The Karolinska Institute, Stockholm, Sweden, ³Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ⁴Medicine, Rheumatology Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden, ⁵Dept. of Rheumtology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, ⁷Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁸Department of Rheumatology, Ambroise Paré Hospital, Boulogne-Billancourt, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital, Boulogne-Billancourt, Paris, France, Paris, France, ⁹Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Dept. of Medicine, Karolinska institutet, Stockholm, Sweden
Background/Purpose: Doppler ultrasound plays an increasing role for monitoring disease activity in rheumatoid arthritis (RA). This study aimed to evaluate the association between two semi-quantitative…
Abstract Number: 1289 • 2016 ACR/ARHP Annual Meeting
Comparison of Clinical Parameters and PET/MRI in Juvenile Idiopathic Arthritis
Kathleen Jo Corbin¹, Emily von Scheven¹, Youngho Seo², Spencer Behr² and John MacKenzie³, ¹Division of Rheumatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, ²Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ³Section of Pediatric Radiology, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA
Background/Purpose: Positron emission tomography (PET) can be used to identify inflammation using 18F-fluorodeoxyglucose (18F-FDG). 18F-FDG uptake correlates with clinical and laboratory markers of disease activity…
Abstract Number: 135 • 2016 ACR/ARHP Annual Meeting
The 8-Joint Ultrasound Score Is a Useful Marker for Monitoring Therapeutic Response in Rheumatoid Arthritis
Ryusuke Yoshimi¹, Yukihiro Toyota¹, Naomi Tsuchida¹, Yumiko Sugiyama¹, Yosuke Kunishita¹, Daiga Kishimoto¹, Reikou Kamiyama¹, Kaoru Minegishi², Maasa Tamura¹, Yukiko Asami¹, Yohei Kirino¹, Shigeru Ohno² and Hideaki Nakajima¹, ¹Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan, ²Center for Rheumatic Disease, Yokohama City University Medical Center, Yokohama, Japan
Background/Purpose: Musculoskeletal ultrasonography (US) is one of the standard tools for the diagnosis and monitoring of rheumatoid arthritis (RA). Although we and other groups have…
Abstract Number: 1296 • 2016 ACR/ARHP Annual Meeting
Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion Volume in Knee Osteoarthritis
Lena Franziska Schaefer¹, Ming Yin¹, Meera Sury², Scott Jamieson¹, Jamie E. Collins³, Stacy Smith⁴ and Jeffrey Duryea¹, ¹Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ²Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ³Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ⁴Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA
Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion volume in Knee Osteoarthritis Schaefer L.F., Yin M., Sury, M., Jamieson S., Collins J., Smith S.,…
Abstract Number: 1381 • 2015 ACR/ARHP Annual Meeting
The Relationship Between Serum Cholinesterase, Number of Organ Involvement and Fibrotic Markers in Japanese Patients with IgG4-Related Disease
Hirofumi Nishikawa¹, Yoshinori Taniguchi¹, Yoshiko Shimamura¹, Kosuke Inoue¹, Taro Horino¹, Susumu Nishiyama², Yasuhiko Yoshinaga² and Yoshio Terada¹, ¹Kochi University, Nankoku, Japan, ²Kurashiki Medical Center, Kurashiki, Japan
Background/Purpose: To evaluate the relationship between cholinesterase, number of organ involvement and serum fibrotic markers in Japanese patients with IgG4-related disease (IgG4-RD). Methods: The clinical…
Abstract Number: 1445 • 2015 ACR/ARHP Annual Meeting
Physicians’ Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis
Yongdong Zhao¹, Fatma Dedeoglu², Polly J. Ferguson³, Sivia Lapidus⁴, Ronald Laxer⁵, Suzanne C. Li⁶ and for the CARRA SVRD subcommittee, ¹Pediatric Rheumatology, Seattle Children's Hospital, Seattle, WA, ²Rheumatology, Boston Children's Hospital, Boston, MA, ³Dept of Pediatrics--Rheum, University of Iowa, Iowa City, IA, ⁴Pediatric Rheumatology, Goryeb Children's Hospital, Morristown, NJ, ⁵Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁶Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ
Background/Purpose: Chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), is an autoinflammatory bone disease of unknown cause that can result in…
Abstract Number: 1505 • 2015 ACR/ARHP Annual Meeting
Carotid Artery Atherosclerosis in Patients with Active Rheumatoid Arthritis: Predictors of Plaque Occurrence and Progression over 24 Weeks
Tatiana Nevskaya¹, Janet E. Pope², Lillian Barra³ and Grace Parraga⁴, ¹Medicine, Division of Rheumatology, University of Western Ontario, London, ON, Canada, ²University of Western Ontario, London, ON, Canada, ³Medicine, Division of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ⁴University of Western Ontario, Robarts Research Institute, London, ON, Canada
Background/Purpose: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). Methods: Carotid arteries of RA patients were scanned…
Abstract Number: 1595 • 2015 ACR/ARHP Annual Meeting
Impaired Coronary Flow Reserve in Rheumatoid Arthritis: A Robust Indicator of Cardiac Structure Associated with Systemic Inflammation and Rheumatoid Arthritis Treatments
Isabelle Amigues¹, Jon T. Giles¹, Sabahat Bokhari², Afshin Zartoshti³, Richard Weinberg², Cesare Russo⁴ and Joan Bathon³, ¹Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Cardiology, Columbia University Medical Center, NY, NY, ³Rheumatology, Columbia University Medical Center, NY, NY, ⁴Division of Cardiology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Myocardial microvascular dysfunction may precede or coexist with coronary atherosclerosis and heart failure, two conditions over-represented in RA. Coronary flow reserve (CFR) offers an…

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