Abstracts tagged "Imaging"

Abstract Number: 1289 • 2016 ACR/ARHP Annual Meeting
Comparison of Clinical Parameters and PET/MRI in Juvenile Idiopathic Arthritis
Kathleen Jo Corbin¹, Emily von Scheven¹, Youngho Seo², Spencer Behr² and John MacKenzie³, ¹Division of Rheumatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, ²Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ³Section of Pediatric Radiology, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA
Background/Purpose: Positron emission tomography (PET) can be used to identify inflammation using 18F-fluorodeoxyglucose (18F-FDG). 18F-FDG uptake correlates with clinical and laboratory markers of disease activity…
Abstract Number: 135 • 2016 ACR/ARHP Annual Meeting
The 8-Joint Ultrasound Score Is a Useful Marker for Monitoring Therapeutic Response in Rheumatoid Arthritis
Ryusuke Yoshimi¹, Yukihiro Toyota¹, Naomi Tsuchida¹, Yumiko Sugiyama¹, Yosuke Kunishita¹, Daiga Kishimoto¹, Reikou Kamiyama¹, Kaoru Minegishi², Maasa Tamura¹, Yukiko Asami¹, Yohei Kirino¹, Shigeru Ohno² and Hideaki Nakajima¹, ¹Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan, ²Center for Rheumatic Disease, Yokohama City University Medical Center, Yokohama, Japan
Background/Purpose: Musculoskeletal ultrasonography (US) is one of the standard tools for the diagnosis and monitoring of rheumatoid arthritis (RA). Although we and other groups have…
Abstract Number: 1296 • 2016 ACR/ARHP Annual Meeting
Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion Volume in Knee Osteoarthritis
Lena Franziska Schaefer¹, Ming Yin¹, Meera Sury², Scott Jamieson¹, Jamie E. Collins³, Stacy Smith⁴ and Jeffrey Duryea¹, ¹Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ²Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ³Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ⁴Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA
Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion volume in Knee Osteoarthritis Schaefer L.F., Yin M., Sury, M., Jamieson S., Collins J., Smith S.,…
Abstract Number: 162 • 2016 ACR/ARHP Annual Meeting
Automated Segmentation of Cartilage Provides Comparable Accuracy and Better Responsiveness Than Manual Segmentation: Data from the Osteoarthritis Initiative
Gwenael Guillard¹, Graham R. Vincent¹, Philip G. Conaghan², Alan Brett³ and Michael A Bowes¹, ¹Imorphics Ltd, Manchester, United Kingdom, ²NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ³Imorphics Ltd, MANCHESTER, United Kingdom
Automated Segmentation of Cartilage Provides Comparable Accuracy and Better Responsiveness Than Manual Segmentation: Data from the Osteoarthritis Initiative *Guillard G., *Vincent G.R., *Brett, A., **Conaghan,…
Abstract Number: 1304 • 2016 ACR/ARHP Annual Meeting
2D and 3D Measurements of Osteoarthritis Joint Space Width Have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from the Osteoarthritis Initiative
Aaron Ray¹, Michael A Bowes², Bright Dube¹, Elizabeth M.A. Hensor¹, Andrew J Barr¹ and Philip G. Conaghan¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom
2D and 3D Measurements of Osteoarthritis Joint Space Width have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from…
Abstract Number: 169 • 2016 ACR/ARHP Annual Meeting
Ultrasound and Magnetic Resonance Imaging Fusion of Images and B-Flow Evaluation of Tenosynovitis – a Pilot Study on New Imaging Techniques in Rheumatoid Arthritis Patients
Mads Ammitzbøll-Danielsen^1,2, Daniel Glinatsi^2,3, Søren Torp-Pedersen⁴, Esperanza Naredo⁵, Mikkel Ostergaard² and Lene Terslev⁶, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, ²Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, ³Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ⁴Department of Diagnostics, Rigshospitalet, Glostrup, Copenhagen, Denmark, ⁵Rheumatology, Hospital General Universitario Gregorio Marañón and Universidad Complutense, Madrid, Spain, ⁶Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark
Background/Purpose: Image fusion is an advanced imaging technology, which enables fusion of ultrasound (US) and magnetic resonance imaging (MRI). This fusion gives for each…
Abstract Number: 1328 • 2016 ACR/ARHP Annual Meeting
Infective Endocarditis with Septic Arthritis: A Single-Center Experience
Sarah B. Lieber¹, Robert Shmerling², Andy Moore³, Mary Louise Fowler⁴, Kunwal Nasrullah⁵ and Ziv Paz¹, ¹Beth Israel Deaconess Medical Center, Boston, MA, ²Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA, ³Division of Rheumatology, Cambridge Health Alliance, Harvard Medical School, Boston, MA, ⁴Boston University School of Medicine, Boston, MA, ⁵Boston University Medical School, BOSTON, MA
Background/Purpose: Echocardiogram is frequently performed on patients presenting with septic arthritis (SA) but rarely demonstrates evidence of infective endocarditis (IE). Similarly, while patients with IE…
Abstract Number: 173 • 2016 ACR/ARHP Annual Meeting
S100A8/A9, a Potent Serum and Molecular Imaging Biomarker for Synovial Inflammation and Joint Destruction in Seronegative Experimental Arthritis
Edwin J. W. Geven¹, Martijn H. J. van den Bosch¹, Shahla Abdolahi-Roodsaz¹, Annet W. Sloetjes¹, Sven Hermann², Michael Schäfers², Marije I. Koenders¹, Dirk Föll³, Johannes Roth⁴, Thomas Vogl⁴ and Peter L. E. M. van Lent¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²European Institute for Molecular Imaging, University of Münster, Münster, Germany, ³Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, ⁴Institute of Immunology, University of Münster, Münster, Germany
Background/Purpose: Seronegative joint diseases, including psoriatic arthritis and juvenile idiopathic arthritis, are characterized by the lack of autoantibodies, which are relevant biomarkers for predicting disease…
Abstract Number: 1444 • 2016 ACR/ARHP Annual Meeting
Differential Expression of Wnt Inhibitors before and after Joint Inflammation Onset in Rat Arthritis Could Partly Explain Paradoxical Effect of Sclerostin Inhibition
Guillaume Courbon¹, Raphaelle Lamarque², Marie-Thérèse Linossier², Norbert Laroche², Thierry Thomas³, Laurence Vico² and Hubert Marotte³, ¹SAINBIOSE INSERM U1059, University of Lyon, Saint-Etienne, France, ²SAINBIOSE INSERM U1059, University of Lyon, Saint Etienne, France, ³SAINBIOSE INSERM U1059 and Rheumatology department, University of Lyon and University Hospital of Saint Etienne, Saint Etienne, France
Background/Purpose: Periarticular bone loss in rheumatoid arthritis is considered to be mainly related to synovial inflammation, leading to uncoupling between decreased bone formation and increased…
Abstract Number: 257 • 2016 ACR/ARHP Annual Meeting
CNS Manifestations of Patients with Muckle-Wells Syndrome
sara Sebnem KILIC¹, sukru cekic² and Juan Aróstegui³, ¹Pedaitric Rheumatology, Prof Dr, Bursa, Turkey, ²Dr, Bursa, Turkey, ³Prof, Barcelona, Spain
Background/Purpose: CAPS is a rare autoinflammatory disease associated with mutations in the NLRP3 gene that result in overactivation of the inflammasome, increased secretion of IL-1beta…
Abstract Number: 1577 • 2016 ACR/ARHP Annual Meeting
An Investigation of Translocator Protein As a Tissue and Peripheral Blood Biomarker of Inflammation in Rheumatoid Arthritis
Nehal Narayan¹, Francesco Carlucci² and Peter C. Taylor³, ¹Rheumatology, University of Oxford, Oxford, United Kingdom, ²The Botnar Research Centre, University of Oxford, oxford, United Kingdom, ³Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom
Background/Purpose: Translocator protein (TSPO) is a mitochondrial cholesterol transporter, utilised in diseases as a Positron Emission Tomography (PET) imaging marker of macrophage infiltration. Recent observations…
Abstract Number: 162 • 2015 ACR/ARHP Annual Meeting
Ultrasonography Versus Clinical Examination in Early DMARD-Naïve Rheumatoid Arthritis – a Comparative Study of Synovitis on the Individual Joint Level
Lena B. Nordberg¹, Elisabeth Lie¹, Siri Lillegraven¹, Anna-Birgitte Aga¹, Inge C Olsen², Hilde Berner Hammer³, Till Uhlig⁴, Désirée van der Heijde⁵, Tore K. Kvien¹, Espen A. Haavardsholm¹ and the ARCTIC Study Group, ¹Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Diakonhjemmet Hospital, Oslo, Norway, ⁵Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Ultrasonography (US) is increasingly accepted as an important tool in diagnosis and management of rheumatoid arthritis (RA). However, it is not well known to…
Abstract Number: 1693 • 2015 ACR/ARHP Annual Meeting
High Prevalence of Cardiac Disease in Patients with Ankylosing Spondylitis
Sjoerd C. Heslinga¹, Thelma C. Konings², Otto Kamp², Mike J.L. Peters³, Yvo M. Smulders³, Irene E. Van der Horst - Bruinsma¹ and Mike T. Nurmohamed¹, ¹Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, ²Cardiology, VU University Medical Center, Amsterdam, Netherlands, ³Internal Medicine, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Ankylosing spondylitis (AS) is associated with increased risk of concomitant cardiac disease, such as valvular regurgitation, conduction disturbances and decreased ventricular function (1). However,…
Abstract Number: 188 • 2015 ACR/ARHP Annual Meeting
Whole-Body Synovial Uptake of a 99mtc-Labelled RGD Peptide Is Highly Correlated with Power Doppler Ultrasound
Toby Garrood¹, Matthew Morrison², Dharsha Shivapatham³, Khaldoun Chaabo¹, Fahim Ul-Hassan⁴, Jim Ballinger⁴, Gary Cook⁵ and Andrew P. Cope⁶, ¹Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ²GE Healthcare, Amersham, United Kingdom, ³Department of Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ⁴Nuclear Medicine, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ⁵Imaging Sciences, Kings College London, London, United Kingdom, ⁶Academic Department of Rheumatology, King´s College London, London, United Kingdom
Background/Purpose: Musculoskeletal ultrasound, and specifically power Doppler ultrasound (PDUS), is more sensitive than clinical examination for the assessment of active synovitis in patients with rheumatoid…
Abstract Number: 1767 • 2015 ACR/ARHP Annual Meeting
Noninvasive Assessment of Macrophage Activation in Experimental Glomerulonephritis Using Optical Imaging with Near-Infrared Light Serves As a Surrogate of Disease Activity
Sebastian Braehler¹, Dongyue Huang², Matthew Cheung², Walter Akers³ and Alfred Kim², ¹Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO, ²Rheumatology, Washington University School of Medicine, Saint Louis, MO, ³Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO
Background/Purpose: Glomerulonephritis (GN) represents a major cause of morbidity & mortality. The standard for diagnosing GN is through renal biopsy, but this is not performed…

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