Abstracts tagged "Imaging"

Abstract Number: 854 • 2019 ACR/ARP Annual Meeting
Do Smoking and Socio-economic Factors Independently Influence Imaging Outcomes in Axial Spondyloarthritis? Five-year Data from the DESIR Cohort
Elena Nikiphorou¹, Sofia Ramiro ², Alexandre Sepriano ³, Adeline Ruyssen Witrand ⁴, Robert B.M. Landewé ⁵ and Désirée van der Heijde ³, ¹King's College London, London, United Kingdom, ²Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology center, Pierre Paul Riquet Hospital, CHU of Toulouse, Paul Sabatier University, UMR 1027, Inserm, France, Toulouse, France, ⁵Amsterdam University Medical Center, Amsterdam, Netherlands
Background/Purpose: Smoking and systemic inflammation have been shown to independently associate with radiographic spinal progression in patients with axSpA. Evidence suggests that certain socioeconomic (SE)…
Abstract Number: 959 • 2019 ACR/ARP Annual Meeting
A Novel Image Analysis Program, “CytoSkaler”, Demonstrates That Anti-Vimentin Antibody Affinity Maturation in Lupus Tubulointerstitial Nephritis Also Results in More Selective Antigen Targeting
Andrew Kinloch¹, Aazam Mohsin ¹, Yuta Asano ¹, Carole Henry ¹, Nirit Mor Vaknin ², Maureen Legendre ², Patrick Wilson ¹, David Markovitz ² and Marcus Clark ¹, ¹University of Chicago, Chicago, IL, ²University of Michigan, Ann Arbor, MI
Background/Purpose: Vimentin is a dominant target of B-cells selected in lupus tubulointerstial inflammation (TII), a predictor of renal failure. The origins of anti-vimentin antibodies (AVA)…
Abstract Number: 1172 • 2019 ACR/ARP Annual Meeting
The Relationship Between Subclinical Inflammation and Bone Damage in Patients with Rheumatoid Arthritis Using Multimodality Imaging
Scott Brunet ¹, Peter Salat ², Glen Hazlewood ³, Klaus Engelke ⁴, Cheryl Barnabe ³ and Sarah Manske³, ¹University of Calgary, Calgary, Canada, ²University of Calgary, Calary, Canada, ³University of Calgary, Calgary, AB, Canada, ⁴Erlangen University Hospital, Department of Medicine, Erlangen, Germany
Background/Purpose: Many RA patients in clinical remission have evidence of bone marrow edema (BME) on magnetic resonance imaging (MRI), with radiographic bone damage progression appearing…
Abstract Number: 1177 • 2019 ACR/ARP Annual Meeting
Near Infrared Indocyanine Green Imaging Reveals Altered Anatomy and Diminished Function in Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients During Flare
Richard Bell¹, Homaira Rahimi ², Alicia Lieberman ², Ronald Wood ², Edward Schwarz ³ and Christopher Ritchlin ⁴, ¹University of Rochester Medical Center, Rochester, NY, ²University of Rochester Medical Center, Rochester, ³University of Rochester, Rochester, NY, ⁴Division of Allergy, Immunology and Rheumatology, Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA, Rochester, NY
Background/Purpose: Near infrared (NIR) imaging of indocyanine green (ICG) in rheumatoid arthritis (RA) models identified abnormal lymphatic vessel (LV) function, which can be quantified as…
Abstract Number: 1877 • 2019 ACR/ARP Annual Meeting
Romosozumab Improves Lumbar Spine Bone Mineral Density and Bone Strength Greater Than Alendronate as Assessed by Quantitative Computed Tomography and Finite Element Analysis in the ARCH Trial
Jacques Brown¹, Arkadi Chines ², Roland Chapurlat ³, Joseph Foldes ⁴, Xavier Nogues ⁵, Roberto Civitelli ⁶, Tobias De Villiers ⁷, Fabio Massari ⁸, Cristiano A. Zerbini ⁹, Wenjing Yang ², Chris Recknor ¹⁰ and Cesar Libanati ¹¹, ¹CHU de Quebec Research Centre and Laval University, Quebec, QC, Canada, ²Amgen Inc., Thousand Oaks, CA, ³INSERM UMR 1033, Université de Lyon, Lyon, France, ⁴Hadassah Hebrew University Medical Center, Jerusalem, Israel, ⁵IMIM Institut Hospital del Mar d’Investigacions Mèdiques, Barcelona, Spain, ⁶Washington University School of Medicine, St. Louis, MO, ⁷Stellenbosch University, Stellenbosch, South Africa, ⁸Instituto de Investigaciones Metabólicas, Buenos Aires, Argentina, ⁹Centro Paulista de Investigação Clinica, São Paulo, Brazil, ¹⁰United Osteoporosis Centers, Gainesville, GA, ¹¹UCB Pharma, Brussels, Belgium
Background/Purpose: Recent evidence suggests BMD achieved during treatment is a reliable surrogate for fracture risk reduction (Bouxsein JBMR 2019). Romosozumab (Romo) is a bone-forming agent…
Abstract Number: 1919 • 2019 ACR/ARP Annual Meeting
Development of a Multi-Modality Imaging Approach to Evaluate Lupus Nephritis
Amit Saxena ¹, David Karp ², Brad Rovin ³, Mikael Boesen ⁴, Olga Kubassova ⁵, Claire Dykas ⁶, Anthony Yeo ⁷ and Peter Lipsky⁸, ¹New York University School of Medicine, New York, NY, ²UTSouthwestern Medical Center, Dallas, TX, ³The Ohio State University Medical Center, Columbus, OH, ⁴Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ⁵Image Analysis Group, London, United Kingdom, ⁶AmpelBioSolutions, Charlottesville, VA, ⁷RILITE Research Institute, Charlottesville, VA, ⁸AMPEL BioSolutions, LLC, Charlottesville, VA
Background/Purpose: Lupus nephritis (LN) remains a significant cause of morbidity and mortality in subjects with Systemic Lupus Erythematosus (SLE). The gold standard for evaluation of…
Abstract Number: 2923 • 2019 ACR/ARP Annual Meeting
Clinical Subsets in Giant Cell Arteritis
K Bates Gribbons¹, Cristina Ponte ², Anthea Craven ³, Joanna Robson ⁴, Ravi Suppiah ⁵, Richard Watts ⁶, Raashid Luqmani ³, Peter Merkel ⁷ and Peter C. Grayson ⁸, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ³University of Oxford, Oxford, United Kingdom, ⁴Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ⁵Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ⁶Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ⁷University of Pennsylvania, Philadelphia, PA, ⁸National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Giant cell arteritis (GCA) is a clinically heterogeneous disease. Disease subsets based upon cranial versus extracranial artery involvement have been proposed. The study objective…
Abstract Number: 279 • 2019 ACR/ARP Annual Meeting
Comparison of Carotid Ultrasound and Coronary Artery Calcium Score in Cardiovascular Risk Stratification of Patients with Inflammatory Rheumatic Diseases
Keith Colaco¹, Elsie Nguyen ², Shadi Akhtari ³, Paula Harvey ³ and Lihi Eder ⁴, ¹University of Toronto, Women's College Hospital, University Health Network, Toronto, ON, Canada, ²University Health Network, Toronto, ON, Canada, ³Women's College Hospital, Toronto, ON, Canada, ⁴Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada
Background/Purpose: The value of non-invasive vascular imaging for cardiovascular (CV) risk stratification of patients with inflammatory rheumatic diseases is unclear. Measures of atherosclerosis including coronary…
Abstract Number: 285 • 2019 ACR/ARP Annual Meeting
Thermal Imaging in Rheumatoid Arthritis: A Comparative Analysis with Ultrasonography and Clinical Joint Assessment
York Kiat Tan¹, Cassandra Hong ¹, HuiHua Li ², John Carson Allen Jr ³ and Julian Thumboo ¹, ¹Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, ²Health Services Research, Singapore General Hospital, Singapore, Singapore, ³Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore
Background/Purpose: The potential of thermal imaging in detecting joint inflammation in rheumatoid arthritis (RA) has not been well studied or compared with other approaches in…
Abstract Number: 297 • 2019 ACR/ARP Annual Meeting
Ultrasound and Magnetic Resonance Imaging Evaluation of the Fingers’ Joints of Psoriatic Arthritis Patients – Interim Analysis
Ari Polachek¹, Victoria Furer ², Mirna Zureik ², Sharon Nevo ², Liran Mendel ², David Levartovsky ³, Jonathan Wollman ⁴, Valerie Aloush ⁵, Mark Berman ⁶, Ilana Kaufman ⁶, Yael Lahat ², Hagit Sarbagil-Maman ⁷, Sara Borok ⁶, Adi Broyde ⁶, Lihi Eder ⁸, Daphna Paran ¹, Iris Eshed ⁹ and Ori Elkayam ¹⁰, ¹Tel-Aviv Sourasky medical center, Tel Aviv, Israel, ²Sourasky Medical Center, Tel-Aviv, Israel, ³Sourasky medical center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Herzelia, Israel, ⁵Tel Aviv Sourasky medical center, Tel Aviv, ⁶Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, ⁸Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada, ⁹Sheba Medical Center, Tel-Aviv, Israel, ¹⁰Rheumatology Department, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel., Tel Aviv, Israel
Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory disease affecting up to 30% of psoriasis patients. PsA can involve both the peripheral and axial skeleton and…
Abstract Number: 568 • 2019 ACR/ARP Annual Meeting
Understanding mNY Radiograph Score Discordance in Axial Spondyloarthritis Clinical Trials Using Imaging Criteria for Subject Eligibility
Farhan Syed¹, Kassel Fotinos-Hoyer ², Michael O'Connor ³, Maureen Li ³, Bryan Hermannsson ², Nicholas Enus ³, Sayali Karve ³, Manish Sharma ⁴, Gabriele Pradella ³, Robert B.M. Landewé ⁵, Xenofon Baraliakos ⁶ and Sarah Warner ³, ¹Parexel, Billerica, MA, ²Parexel, Berlin, Germany, ³Parexel, Billerica, ⁴Parexel, Hyderabad, India, ⁵Amsterdam University Medical Center, Amsterdam, Netherlands, ⁶Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany
Background/Purpose: Axial spondyloarthritis (axSpA) is typically radiographically confirmed on the sacroiliac joint (SIJ) as assessed by the modified New York (mNY) criteria. In clinical trials,…
Abstract Number: 968 • 2018 ACR/ARHP Annual Meeting
What Is the Impact of Imaging on Diagnostic Ascertainment of Patients Presenting with Undiagnosed Back Pain in Routine Practice and the Impact of Central Reading? Data from the Screening in Axial Spondyloarthritis in Psoriasis, Iritis, and Colitis Cohort
Walter P. Maksymowych^1,2, Raj Carmona³, Jonathan Chan⁴, James Yeung⁵, Dianne P. Mosher⁶, Sibel Zehra Aydın⁷, Liam Martin⁶, Ariel Masetto⁸, Stephanie Keeling⁹, Olga Ziouzina⁶, Sherry Rohekar¹⁰, Joel Paschke², Amanda Carapellucci² and Robert G. Lambert¹¹, ¹Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³St. Joseph's Health Care, Hamilton, ON, Canada, ⁴Artus Health Clinic, Vancouver, BC, Canada, ⁵James Yeung Rheumatology, Richmond, BC, Canada, ⁶University of Calgary, Calgary, AB, Canada, ⁷Ottawa Hospital, Ottawa, ON, Canada, ⁸Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, AB, Canada, ⁹Medicine, University of Alberta, Edmonton, AB, Canada, ¹⁰Western University, London, ON, Canada, ¹¹Radiology, Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Although MRI of the sacroiliac joints (SIJ) is the most sensitive imaging modality for early diagnosis of axial spondyloarthritis (axSpA) it is costly and…
Abstract Number: 1203 • 2018 ACR/ARHP Annual Meeting
Tenosynovitis Detected By Ultrasound Predicts Arthritis Onset in Individuals at Risk of Developing Rheumatoid Arthritis
Yogan Kisten¹, Hamed Rezaei¹, Erik af Klint¹, Guozhong Fei^1,2, Aleksandra Antovic^1,2, Aase Hensvold^1,2 and Anca I. Catrina^1,2, ¹Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ²Stockholm Health Services, Academic Specialist Center, Center for Rheumatology, Stockholm, Sweden
Background/Purpose: The urgent need for identifying imaging and serological markers that early predicts rheumatoid arthritis (RA) is clinically important. We aim to identify ultrasound findings…
Abstract Number: 1277 • 2018 ACR/ARHP Annual Meeting
A Prospective Study Examining the Prevalence of CT Erosions in the Feet and Ankles of Patients with Gout Treated with Allopurinol
Chio Yokose¹, Yuqing Zhang², Nicola Dalbeth³, Jie Wei¹, Savvas Nicolaou⁴, Scott Baumgartner⁵, Jia Hu⁶, Maple Fung⁵ and Hyon K. Choi¹, ¹Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ²Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ³University of Auckland, Auckland, New Zealand, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Formerly Ardea Biosciences, San Diego, CA, ⁶Heron Therapeutics, San Diego, CA
Background/Purpose: Gout is characterized by episodes of acute arthritis that are self-limiting. However, patients with gout can also develop tophi, bone erosions, joint deformity and…
Abstract Number: 1285 • 2018 ACR/ARHP Annual Meeting
Comparision of Urate Burden in Well and Poorly Controlled Gout Patients: A Dual-Energy CT Study
Min Kyung Chung¹, Hyeran Hyun², Ji Young Hwang² and Jisoo Lee¹, ¹Division of Rheumatology, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea, Republic of (South), ²Department of Radiology, Ewha Womans University School of Medicine, Seoul, Korea, Republic of (South)
Background/Purpose: Dual-energy computed tomography (DECT) allows sensitive and quantative detection of monosodium urate (MSU) crystals in patients with gout. Although its usefulness in diagnosing gout…

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