ACR Meeting Abstracts

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Abstracts tagged "Imaging"

  • Abstract Number: 1551 • ACR Convergence 2020

    Rapid Effect of Tofacitinib in Reducing US Joint and Tendon Inflammatory Lesions of RA Patients: Data from a 24 Weeks Longitudinal Study

    Giuseppe Germanò1, Pierluigi Macchioni2, Giovanni Ciancio3, Filippo Crescentini1, Andrea Caruso2, Beatrice Maranini4, Sara Bonazza4, Gilda Sandri5, Maria Teresa Mascia5, Govoni Marcello4 and Carlo Salvarani6, 1Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, REGGIO NELL'EMILIA, Emilia-Romagna, Italy, 2Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, REGGIO NELL'EMILIA, Italy, 3Unità Operativa Complessa di Reumatologia Azienda Ospedaliero-Universitaria S. Anna -Ferrara, Ferrara, Emilia-Romagna, Italy, 4Unità Operativa Complessa di Reumatologia Azienda Ospedaliero-Universitaria S. Anna -Ferrara, Ferrara, Italy, 5Struttura Complessa di Reumatologia- Università di Modena e Reggio Emilia- Policlinico di Modena, Modena, Italy, 6Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, Reggio Emilia, Italy

    Background/Purpose: To explore the effects of tofacitinib (Tofa) on US lesions in a consecutive series of patients with active RA MTX and/or bioDMARDs -IR. Methods: In…
  • Abstract Number: 2021 • ACR Convergence 2020

    The Reliability of Scoring Sonographic Entheseal Abnormalities – the Diagnostic Ultrasound Enthesitis Tool (DUET) Study

    Lihi Eder1, Sibel Aydin2 and Gurjit Kaeley3, 1Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, 2University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, Ottawa, ON, Canada, 3University of Florida College of Medicine - Jacksonville, Jacksonville, FL

    Background/Purpose: DUET is a study supported by the Group for Assessment for Psoriasis and Psoriatic Arthritis (GRAPPA) that aims to develop a novel sonographic scoring…
  • Abstract Number: 0648 • ACR Convergence 2020

    Dual Energy CT Has Additional Prognostic Value over Clinical Measures in Gout Including Tophi: Best Evidence Synthesis

    Sally Stauder1 and Paul Peloso2, 1Tulane University, Ponte Vedra Beach, FL, 2Horizon Therapeutics plc, Gurnee, IL

    Background/Purpose: Dual Energy CT Scan (DECT) can detect monosodium urate crystals in joints and periarticular tissues. EULAR gout guidelines (Richette, 2020) recognized DECT's value in…
  • Abstract Number: 1331 • ACR Convergence 2020

    Carotid Ultrasound Findings in Psoriatic Arthritis: A Case-control Study

    Dionicio Ángel Galarza-Delgado1, José Ramón Azpiri López2, Iris Jazmín Colunga Pedraza3, Diana Elsa Flores Alvarado4, Octavio Ilizaliturri Guerra4, Paola Fernanda Frausto Lerma3, Itzel Corina Zárate Salinas2, Alejandra Pérez Villar3, Mayra Alejandra Reyes Soto3, Salvador Lugo Pérez2 and Andrea Cecilia Garza Acosta5, 1Rheumatology Service, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma Nuevo León, Monterrey, Nuevo Leon, Mexico, 2Cardiology Service, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma Nuevo León, Monterrey, Mexico, 3Rheumatology service, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma Nuevo León, Monterrey, Mexico, 4Rheumatology Service, Hospital Universitario “Dr. José Eleuterio González, Universidad Autónoma Nuevo León, Monterrey, Nuevo Leon, Mexico, 5Radiology Service, Hospital Universitario “Dr. José Eleuterio González, Universidad Autónoma Nuevo León, Monterrey, Nuevo Leon, Mexico

    Background/Purpose: Patients with psoriatic arthritis (PsA) have an increased risk of cardiovascular disease (CVD). The carotid ultrasound, which measures both carotid intima-media thickness (cIMT) and…
  • Abstract Number: 1553 • ACR Convergence 2020

    Optical Tomography Can Accurately Diagnose Lupus Arthritis

    Wei Tang1, Alessandro Marone2, Youngwan Kim2, Tommy Chen1, Cathy Guo1, Leila Khalili1, Andreas Hielscher2 and Anca Askanase3, 1Columbia University Medical Center, New York, NY, 2Columbia University, New York, NY, 3Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Incapacitating inflammatory arthritis occurs in up to 88% of patients with systemic lupus erythematosus (SLE). Arthritis is present in 70-80% of lupus patients in…
  • Abstract Number: 2034 • ACR Convergence 2020

    Resolving Phenotypic and Prognostic Differences in Interstitial Lung Disease Related to Systemic Sclerosis by Computed Tomography-based Radiomics

    Janine Schniering1, Malgorzata Maciukiewicz1, Hubert Gabrys2, Matthias Brunner1, Christian Blütghen3, Chantal Meier1, Sophie Braga-Lagache4, Anne-Christine Ulgry4, Manfred Heller4, Oliver Distler1, Matthias Guckenberger2, Havard Fretheim5, Anna-Maria Hoffmann-Vold5, Christos Nakas6, Thomas Frauenfelder3, Stephanie Tanadini-Lang2 and Britta Maurer7, 1Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, Switzerland, 2Department of Radiation Oncology, University Hospital Zurich, Switzerland, Zurich, Switzerland, 3Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Switzerland, Zurich, Switzerland, 4Proteomics and Mass Spectrometry Core Facility, Department for BioMedical Research (DBMR), University of Bern, Switzerland, Bern, Switzerland, 5Department of Rheumatology, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Norway, Oslo, Norway, 6Laboratory of Biometry, University of Thessaly, Volos, Greece, Volos, Greece, 7Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich

    Background/Purpose: Radiomics describes the in-depth analysis of tissue phenotypes by computational retrieval of high-dimensional quantitative imaging features including tissue intensity, texture, and wavelet characteristics. Here,…
  • Abstract Number: 0681 • ACR Convergence 2020

    Gout and Serum Urate Levels Are Associated with Lumbar Spine Monosodium Urate Deposition and Chronic Low Back Pain: A Dual-Energy CT Study

    Michael Toprover1, Michael Mechlin2, Anastasia Slobodnick3, Virginia Pike4, Cheongeun Oh5, Claudine Davis2, Theodore Fields6, Fabio Becce7 and Michael Pillinger8, 1New York University Langone Health, New York, NY, 2NYU Langone Health, New York, NY, 3Stamford Health Medical Group, Stamford, CT, 4NYU Langone Health, Brooklyn, NY, 5NYU Grossman School of Medicine, New York, 6Hospital for Special Surgery, New York, NY, 7Lausanne University, Lausanne, Switzerland, 8New York University Grossman School of Medicine, New York,, NY

    Background/Purpose: Spinal gout is reported as a rare event, presenting as acute back pain, neuropathy, and spinal compression. Diagnosis is commonly based on identification of…
  • Abstract Number: 1382 • ACR Convergence 2020

    Changes in Imaging Markers in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) Treated with Nintedanib: Sub-Study of the SENSCIS Trial

    Stephen Humphries1, Eric Hachulla2, Mark Hamblin3, Takashi Ogura4, Dag Wormanns5, Carina Ittrich6, Frank Risse6, Margarida Alves7, Martina Gahlemann8 and David Lynch9, 1National Jewish Health, Denver, Colorado, USA, Denver, CO, 2Department of Internal Medicine and Clinical Immunology, Université de Lille, Lille, France, Lille, France, 3University of Kansas Hospital, Kansas City, Kansas, USA, Kansas City, KS, 4Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Centre, Yokohama, Japan, Yokohama, Japan, 5Evangelische Lungenklinik, Berlin, Germany, Berlin, Germany, 6Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany, Biberach an der Riss, Germany, 7Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany, Ingelheim am Rhein, Germany, 8Boehringer Ingelheim (Schweiz) GmbH, Basel, Switzerland, Basel, Switzerland, 9National Jewish Health, Denver, Colorado, USA, Denver

    Background/Purpose: In the SENSCIS trial in patients with SSc-ILD, nintedanib reduced the rate of decline in forced vital capacity (FVC) (mL/year) over 52 weeks by…
  • Abstract Number: 1554 • ACR Convergence 2020

    Response to Tocilizumab in Large Vessel Vasculitis According to the Extent of Baseline 18F-FDG Vascular Uptake

    Lara Sanchez-Bilbao1, Diana Prieto-Peña2, Inigo Gonzalez-Mazon3, David Martinez-Lopez4, Monica Calderon-Goercke5, Isabel Martínez-Rodríguez5, Ignacio Banzo5, Miguel Ángel González-Gay6 and Ricardo Blanco1, 1Hospital Universitario Marques de Valdecilla, Santander, Spain, 2Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic bone diseases of the musculoskeletal system, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Hospital Universitario Marques de Valdecilla, Bezana, Spain, 4Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, 5Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, 6Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: 18F-fluodeoxyglucose positron emission tomography (18F-FDG PET/CT) is useful to establish the presence and extent of large vessel vasculitis (LVV). Tocilizumab (TCZ) has shown efficacy…
  • Abstract Number: 0696 • ACR Convergence 2020

    Femoral Cartilage Ultrasound Echo-Intensity Associates with Arthroscopic Cartilage Damage in People Following Anterior Cruciate Ligament Reconstruction

    Matthew Harkey1, Erin Little2, Mikaela Thompson3, Ming Zhang4, Jeffrey Driban4 and Matthew Salzler3, 1University of Massachusetts, Worcester, MA, 2Tufts Medical Center, Cambridge, MA, 3Tufts Medical Center, Boston, 4Tufts Medical Center, Boston, MA

    Background/Purpose: Over one-third of people will develop knee osteoarthritis within 10 years of an anterior cruciate ligament (ACL) injury. Ultrasound may be used to monitor…
  • Abstract Number: 1396 • ACR Convergence 2020

    Digital Artery Volume Index (Davix©) Predicts Onset of Future Digital Ulcers in Patients with Systemic Sclerosis

    Klodian Gjeloshi1, Giovanni Lettieri2, Fiammetta Danzo1, Giuseppina Abignano3, Mark Hinton4, Anne-Maree Dean5, Giovanna Cuomo6, Olga Kubassova7 and Francesco Del Galdo5, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK and Internal Medicine Department, University of Campania Luigi Vanvitelli, Naples, Italy, Leeds, United Kingdom, 2Radiology Department, San Carlo Hospital, Potenza, Italy, Potenza, Italy, 3Rheumatology Institute of Lucania (IReL), Rheumatology Department of Lucania, San Carlo Hospital, Potenza, Italy; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, England, United Kingdom, 4IAG CEO, London, United Kingdom, London, United Kingdom, 5Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom, 6Internal Medicine Department, University of Campania Luigi Vanvitelli, Naples, Italy, Naples, Italy, 7Image Analysis Group, London, United Kingdom

    Background/Purpose: Neointima proliferation is a key pathologic feature of Systemic Sclerosis (SSc), causing arterial vessel narrowing. It is a recognised culprit pathological lesion in Digital…
  • Abstract Number: 1556 • ACR Convergence 2020

    Assessing Calcinosis in Dermatomyositis with Computed Tomography and Calcium Scoring

    Prateek Gowda1, Briana Cervantes2, Lisa G. Rider3, Frederick W. Miller4, Marcus Chen4 and Adam Schiffenbauer4, 1NIBIB, Baltimore, MD, 2NIEHS, Silver Spring, MD, 3Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Garrett Park, MD, 4National Institutes of Health, Bethesda, MD

    Background/Purpose: Calcinosis is a condition in which calcium salts are deposited in and around soft tissue and is observed in up to 30% of adult…
  • Abstract Number: 0080 • ACR Convergence 2020

    Understanding Ankylosing Spondylitis –

    Arnd Kleyer1, Milena Pachowsky2, Louis Schuster1, Larissa Valor-Mendez3, Georg Schett4, Axel Hueber5 and David Simon1, 1Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, 2Department of Orthopedic and Trauma Surgery, FAU Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, 3Department of Internal Medicine 3, Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Bayern, Germany, 4Friedrich-Alexander-Universität Erlangen- Nuremberg, Erlangen, Germany, 5Sozialstiftung Bamberg, Sektion Rheumatologie, Bamberg, Germany

    Background/Purpose: Rheumatology is underrepresented in the medical training of students in Germany. [1] Tools and methods are needed to inspire young students for specialist training…
  • Abstract Number: 0750 • ACR Convergence 2020

    Nuclei Detection in Rheumatoid Arthritis Synovial Tissue Using Artificial Intelligence

    Steven Guan1, David Slater1, James Thompson1, Edward DiCarlo2, Diyu Pearce-Fisher2, Susan Goodman3, Bella Mehta4 and Dana Orange5, 1MITRE, McLean, VA, 2Hospital for Special Surgery, New York, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 4Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 5Rockefeller University, New York

    Background/Purpose: Hematoxylin and eosin (H&E) stained rheumatoid arthritis synovium are routinely used to assess inflammation [1]. In this work, we propose an automated approach using…
  • Abstract Number: 1503 • ACR Convergence 2020

    Ultra High‐resolution Ultrasound (UHFUS) of Labial Salivary Glands Might Help to Avoid Unnecessary Lip Biopsy in Patients with Sicca Syndrome

    Chiara Baldini1, Francesco Ferro1, Rossana Izzetti2, Saverio Vitali3, Giacomo Aringhieri3, Silvia Fonzetti4, Marta Mosca1, Valentina Donati5, Stefano Bombardieri1 and Davide Caramella3, 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 2Department of Surgical Pathology, Medicine, Molecular and Critical Area, University of Pisa, Pisa, Italy, Pisa, 3Diagnostic and Interventional Radiology, Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, Pisa, 4Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, 5Pathology Unit, AOUP, Pisa

    Background/Purpose: Major salivary gland ultrasonography (SGUS) has an established role as a first-line imaging tool in the diagnosis of primary Sjögren’s syndrome (pSS). Nowadays, however,…
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