Abstracts tagged "Imaging"

Abstract Number: 0272 • ACR Convergence 2024
Calcifications of the Transverse Ligament of the Atlas in Patients Diagnosed with Calciumpyrophosphate Crystal Arthritis – a Retrospective Observational Study
Shay Brikman¹, Noga Shabshin² and Amir Bieber³, ¹Emek Medical Center, Afula, Israel, ²Emek Medical Center, Clalit Health Services, Afula, Israel, ³Emek Medical Center, Clalit Health Services, Raanana, Israel
Background/Purpose: Chondrocalcinosis (CC) is commonly detected on X-ray films of the knee, wrist, and symphysis pubis. Calcium pyrophosphate (CPP) deposition disease is sometimes associated with…
Abstract Number: 0851 • ACR Convergence 2024
Diagnostic Ultrasound Enthesitis Tool (DUET) for Psoriatic Arthritis: The Distribution of Elementary Lesions Is Influenced by Site
Lihi Eder¹, Ricardo Acayaba de Toledo², Fahmeen Afgani³, Catherine Bakewell⁴, Philippe Carron⁵, Basant Elnady⁶, Amir Haddad⁷, Arthur Kavanaugh⁸, Arnon Katz⁹, Minna Kohler¹⁰, josefina marin¹¹, NZEUSSEU TOUKAP Adrien¹², Marcos Rosemffet¹³, Ari Polachek¹⁴, Ernesto Rodriguez¹⁵, Ágnes Sarolta Szentpétery¹⁶, Abha Singh¹⁷, Maria S. Stoenoiu¹⁸, Ilaria Tinazzi¹⁹, Janeth Yinh¹⁰, Gurjit Kaeley²⁰ and Sibel Aydin²¹, ¹University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, ²FAMERP, São José do Rio Preto, Brazil, ³Women's College Hospital, Toronto, Canada, ⁴Intermountain Health Care, Salt Lake City, UT, ⁵UZ Gent, Gent, Belgium, ⁶Al Hada Forces Hospital, Rheumatology Department, Taif, Saudi Arabia, ⁷Carmel Medical Centre, Haifa, Israel, ⁸University of California San Diego, La Jolla, CA, ⁹GRAPPA - Patient Research Partner, Haifa, Israel, ¹⁰Massachusetts General Hospital, Boston, MA, ¹¹Hospital Italiano de Buenos Aires, buenos aires, Argentina, ¹²Institut de Recherche Expérimentale et Clinique, Cliniques universitaires Saint-Luc, Université catholique de Louvain, St.-Lambrechts-Woluwe, Belgium, ¹³Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, ¹⁴Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel, ¹⁵Florida Medical Clinic, Tampa, FL, ¹⁶Uppsala University Hospital, Uppsala, Sweden, ¹⁷University of California, San Diego, San Diego, CA, ¹⁸Cliniques Universitaires Saint-Luc, Brussels, Belgium, ¹⁹Ospedale Sacro Cuore-Don Calabria, Verona, Italy, ²⁰UF COM-J, Ponte Vedra Beach, FL, ²¹University of Ottawa - Ottawa, Ottawa, ON, Canada
Background/Purpose: Enthesitis is a key domain in psoriatic arthritis (PsA). The Diagnostic Ultrasound Enthesitis Tool (DUET) study aims to develop a new PsA-specific sonographic scoring…
Abstract Number: 1442 • ACR Convergence 2024
Relationship Between Degenerative Lesions over Time in Axial Spondyloarthritis: 10-year Follow-up of the DESIR Cohort
Laura Pina Vegas¹, Floris van Gaalen², Miranda van Lunteren³, Damien Loeuille⁴, Caroline Morizot⁵, Esther Newsum⁶, Pascal Claudepierre⁷, Alain SARAUX⁸, Antoine Feydy⁹, Monique Reijnierse¹, Desiree van der Heijde¹⁰ and Sofia Ramiro¹¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²LUMC, Leiden, Zuid-Holland, Netherlands, ³Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, ⁴Phd, Nancy Vandoeuvre, Lorraine, France, ⁵Nancy University hospital, Nancy, France, ⁶Nij Smellinghe, Drachten, Netherlands, ⁷CHU Henri Mondor, AP-HP/EpiDermE, UPEC, Créteil, France, ⁸CHU Brest, Brest, France, ⁹CHU Cochin, AP-HP, Paris, France, ¹⁰Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ¹¹Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: Spinal degenerative lesions (DLs) are commonly seen/reported in radiographs and MRI in axSpA. However, the relationship between the different DLs over time has not…
Abstract Number: 1683 • ACR Convergence 2024
68Ga-FAPI PET/CT Imaging for Assessing Renal Tubulointerstitial Fibrosis in Lupus Nephritis
Shuyi Yu, Zetao Ding, Haoyu Pan, Jinyi Qian, Zhixia Yang, Xiaohan Wei, Chengde Yang and Hui Shi, Department of Rheumatology and lmmunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, Shanghai, China (People's Republic)
Background/Purpose: To evaluate the feasibility of using fibroblast activating protein inhibitor (FAPI) PET imaging as a molecular tracer and non-invasive tool for assessing renal tubulointerstitial…
Abstract Number: 2003 • ACR Convergence 2024
Cumulative Incidence of Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis in Lung Cancer Patients with and Without Hip Osteoarthritis and Impacts on Survival
Laura Cappelli¹, Shadpour Demehri¹, Joseph Murray¹, Julie Brahmer¹, Elena Ghotbi¹, Durrant Barasa¹, Clifton Bingham² and Ami Shah³, ¹Johns Hopkins School of Medicine, Baltimore, MD, ²Johns Hopkins University, Baltimore, MD, ³Division of Rheumatology, Johns Hopkins University, Ellicott City, MD
Background/Purpose: Rheumatologists are increasingly called upon to manage patients with inflammatory arthritis (IA) due to immune checkpoint inhibitor (ICI) therapy. The pathogenesis of ICI-IA is…
Abstract Number: 2683 • ACR Convergence 2024
Optical Coherence Angiography: A Non-invasive, Safe Method for Assessing the Systemic Sclerosis Related Vasculopathy Beyond Nailfold Capillaries
Pavel Nikitin¹, Harshdeep Chawla¹, Manmohan Singh¹, Samuel Theodore², Salavat Aglyamov¹, Meng Zhang², Brian Skaug², Maureen Mayes², Kirill Larin¹ and Shervin Assassi², ¹University of Houston, Houston, TX, ²UTHealth Houston Division of Rheumatology, Houston, TX
Background/Purpose: Vascular involvement is a prominent feature of systemic sclerosis (SSc). Safe and non-invasive methods to visualize cutaneous blood vessels beyond nailfold capillaries are lacking.…
Abstract Number: L15 • ACR Convergence 2023
AR882, an Efficacious and Selective URAT1 Inhibitor for Patients with Chronic Gouty Arthritis and Subcutaneous Tophi: Results from a Global, Prospective, Proof-of-Concept Trial Using Dual Energy Computed Tomography
Robert Keenan¹, James Cheng-Chung WEI², Sarah Morris³, Pamella Mundell³, Wen Wei³, Ke Shi³, Zancong Shen³, Vijay Hingorani⁴, Shunqi Yan³, Bahram Kiani⁵ and Litain Yeh³, ¹Arthrosi Therapeutics, Inc., Chapel Hill, NC, ²Chung Shan Medical University, Taichung, Taiwan (Republic of China), ³Arthrosi Therapeutics, Inc., San Diego, CA, ⁴Vanguard Healthsciences, Inc., San Diego, CA, ⁵Wake Forest University School of Medicine, Winston-Salem, NC
Background/Purpose: AR882 is a novel and selective URAT1 inhibitor currently in clinical stage development for the treatment of gout and tophaceous gout and has demonstrated…
Abstract Number: 0812 • ACR Convergence 2023
Length of Synovial Fluid Monosodium Urate Crystals According to Sonographic Articular Deposits: Advancing in the Crystallization Process
Elena Sansano¹, Mª Carmen López-González², Cristina Rodríguez-Alvear³, Irene Calabuig-Sais³, Agustín Martínez-Sanchís³, Eliseo Pascual³ and Mariano Andrés³, ¹Miguel Hernandez University, Alicante, Spain, ²General University Hospital Dr. Balmis, Alacante, Spain, ³Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain
Background/Purpose: We described bands of fibers having deposited orderly arrayed monosodium urate (MSU) crystals suggesting the need for protein templates to start crystallization [PMID 9709185].…
Abstract Number: 1194 • ACR Convergence 2023
Extent of Subregional Involvement of Subchondral Bone Marrow Lesions in Incident Knee OA Is Associated with Weight-Bearing Knee Pain
Kent Kwoh¹, Frank Roemer², Erin Ashbeck³ and Ali Guermazi⁴, ¹University of Arizona, Tucson, AZ, ²Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany, ³University of Arizona Arthritis Center, Tucson, AZ, ⁴Boston University, Boston, MA
Background/Purpose: Subchondral bone marrow lesions (BMLs) have been associated with incident and progressive pain and reported to fluctuate along with concurrent fluctuations in symptoms. While…
Abstract Number: 1650 • ACR Convergence 2023
Optic Nerve Sheath Measurement as a Disease Activity Biomarker in Giant Cell Arteritis
Carolyn Ross¹, Stephanie Ducharme-Benard², Samer Hussein³, Rosalie-Selene Meunier³, Christian Pagnoux⁴ and Jean-Paul Makhzoum¹, ¹Vasculitis Clinic, Canadian Network for Research on Vasculitides, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ²Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ³Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁴Mount Sinai Hospital, Toronto, ON, Canada
Background/Purpose: Recently, optic nerve sheath (ONS) enhancement using contrast-enhanced magnetic resonance imaging of the brain and orbits was observed in most patients with biopsy-proven GCA.…
Abstract Number: 1894 • ACR Convergence 2023
3-Dimensional Regional Variation in Inter-rater Reliability of Bone Marrow Lesion Scoring in the Knee
Stephanie Wichuk¹, Walter P. Maksymowych¹, Joel Paschke², Abhilash Hareendranathan³ and Jacob Jaremko¹, ¹University of Alberta, Edmonton, AB, Canada, ²CARE Arthritis, Edmonton, AB, Canada, ³Radiology and Diagnostic Imaging, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesions (BML) are an important scoring feature on magnetic resonance imaging (MRI) of knee osteoarthritis (OA), and their presence in certain anatomical…
Abstract Number: 2424 • ACR Convergence 2023
Exploring the Limit of Image Resolution for Human Expert Classification of Vascular Ultrasound Images in Giant Cell Arteritis and Healthy Subjects: The GCA-US-AI Project
Valentin Sebastian Schäfer¹, Stavros Chrysidis², Christian Dejaco³, Sara Monti⁴, Matthew Koster⁵, Pantelis Karakostas¹, Wolfgang Schmidt⁶, Eugenio De Miguel⁷, Christina Duftner⁸, Alojzija Hocevar⁹, Annamaria Iagnocco¹⁰, Marcin Milchert¹¹, Chetan Mukhtyar¹², Cristina Ponte¹³, Lene Terslev¹⁴, Tanaz Kermani¹⁵, Uffe Møller Døhn¹⁶, Berit Dalsgaard Nielsen¹⁷, Aaron Juche¹⁸, Luca Seitz¹⁹, Minna Kohler²⁰, Kresten Keller²¹, Rositsa Karalilova²², Thomas Daikeler²³, Sarah Mackie²⁴, Karina Torralba²⁵, Kornelis van der Geest²⁶, Dennis Boumans²⁷, Philipp Bosch²⁸, Alessandro Tomelleri²⁹, Markus Aschwanden³⁰, Peter Brossart¹, Charlotte Behning³¹ and Claus Juergen Bauer¹, ¹Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, ²Department of Rheumatology, Southwest Jutland Hospital Esbjerg, Esbjerg, Denmark, ³Department of Rheumatology, Medical University Graz, Graz, Austria; Department of Rheumatology, Hospital of Bruneck (ASAA-SABES), Teaching Hospital of the Paracelsius Medical University, Brunico, Italy, ⁴Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine and Therapeutics, Università di Pavia, Pavia, Italy, ⁵Mayo Clinic, Rochester, MN, ⁶Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, ⁷Hospital Universitario La Paz, Madrid, Spain, ⁸Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University Innsbruck, Innsbruck, Austria, ⁹Department of Rheumatology, Universitiy Medical Centre Ljubljana, Ljubljana, Slovenia, ¹⁰University of Turin, Roma, Italy, ¹¹Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, ¹²Vasculitis service, Rheumatology department, Norfolk and Norwich University Hospital, Norwich, United Kingdom, ¹³Department of Rheumatology, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisbon, Portugal; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal, ¹⁴Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ¹⁵Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, ¹⁶Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ¹⁷Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark; Department of Medicine, The Regional Hospital in Horsens, Horsens, Denmark, ¹⁸Department of Rheumatology, Immanuel Hospital, Berlin, Germany, ¹⁹Rheumatology and Immunology, Inselspital University Hospital Bern, Bern, Switzerland, ²⁰Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²¹Department of Rheumatology, Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, ²²Clinic of Rheumatology, Medical University Plovdiv, Plovdiv, Bulgaria, ²³Clinic for Rheumatology, University Hospital Basel, Basel, Switzerland, ²⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ²⁵Division of Rheumatology, Department of Medicine, Loma Linda University School of Medicine, Loma Linda, CA, ²⁶Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²⁷Rheumatology and Clinical Immunology, Hospital Group Twente, Almelo, Netherlands, ²⁸Medical University of Graz, Graz, Austria, ²⁹Unit of Immunology, Rheumatology, Allergy and Rare Diseases, San Raffaele Scientific Institute, Milano, Italy, ³⁰Department of Angiology, University Hospital Basel, Basel, Switzerland, ³¹Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany
Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis in adults, necessitating prompt diagnosis to prevent severe complications. However, access to expert…
Abstract Number: 0923 • ACR Convergence 2023
Identification of Lupus Nephritis Kidney Immune Populations via Hi-Resolution 20-Plex Immunohistochemistry Single-Cell Spatial Analyses
Caleb Marlin¹, Alessandra Ida Celia², Richard Furie³, Judith James¹, Andrea Fava⁴, Joel Guthridge¹, Avi Rosenberg⁵, Tayte Stephens¹, Christian Wright¹, Jeff Hodgin⁶, Peter Izmirly⁷, H Michael Belmont⁸, Jennifer Anolik⁹, Michelle Petri¹⁰, Jill Buyon¹¹, Diane L. Kamen¹², Chaim Putterman¹³, Accelerating Medicines Partnership in RA/SLE The¹, Chen-Yu Lee⁴ and Xiaoping Yang⁴, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²John Hopkins University of Medicine, Rome, Italy, ³Northwell Health, Manhasset, NY, ⁴Johns Hopkins University, Baltimore, MD, ⁵Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, ⁶University of Michigan, Ann Arbor, MI, ⁷New York University School of Medicine, New York, NY, ⁸NYU School of Medicine, New York, NY, ⁹University of Rochester Medical Center, Rochester, NY, ¹⁰Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Timonium, MD, ¹¹NYU Grossman School of Medicine, New York, NY, ¹²Medical University of South Carolina, Charleston, SC, ¹³Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Immunohistochemistry is the gold standard for antibody staining in microscopy. However, a lack of multiplexing limits its utility in the use of discovery. Here…
Abstract Number: 1195 • ACR Convergence 2023
Relationship of Depth-Specific Subchondral Bone Mineral Density to MRI Cartilage Worsening: The Multicenter Osteoarthritis Study
Jean Liew¹, JD Johnston², Gabriela Rabasa¹, Beth Lewis³, John Lynch⁴, James Torner⁵ and Tuhina Neogi⁶, ¹Boston University, Boston, MA, ²University of Saskatchewan, Saskatoon, SK, Canada, ³University of Alabama at Birimingham, Birmingham, AL, ⁴University of California San Francisco, San Francisco, CA, ⁵University of Iowa, Iowa City, IA, ⁶Boston University School of Medicine, Boston, MA
Background/Purpose: While OA has been considered a disease of cartilage, early subchondral bone changes may precede cartilage abnormalities. Although higher systemic BMD has a known…
Abstract Number: 1690 • ACR Convergence 2023
Apremilast Reduces Inflammation as Measured by MRI of the Hand in Patients with Psoriatic Arthritis: Primary Results from the Phase 4 MOSAIC Study
Mikkel Østergaard¹, Walter P. Maksymowych², Mikael Boesen³, Robert Lambert⁴, Guillermo Valenzuela⁵, Michael Bubb⁶, Olga Kubassova⁷, Jyotsna Reddy⁸, Stephen Colgan⁹, Yuri Klyachkin¹⁰, Cynthia Deignan¹¹, Lihua Tang⁸, Maria Paris⁸ and Philip J. Mease¹², ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, ²University of Alberta, Edmonton, AB, Canada, ³Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Naerum, Denmark, ⁴Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ⁵Integral Rheumatology & Immunology Specialists, Plantation, FL, ⁶University of Florida, Gainesville, FL, ⁷Image Analysis Group, Philadelphia, PA, ⁸Amgen, Inc., Thousand Oaks, CA, ⁹Amgen, Inc., Halton Hills, ON, Canada, ¹⁰Amgen, Inc., Lexington, KY, ¹¹Amgen, Inc., Agoura Hills, CA, ¹²Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA
Background/Purpose: PsA is characterized by inflammatory arthritis, enthesitis, dactylitis, and spondylitis. Apremilast (APR) is an oral immunomodulating phosphodiesterase-4 inhibitor approved for the treatment of PsA.…

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