Abstracts tagged "Hepatitis C"

Abstract Number: 948 • 2019 ACR/ARP Annual Meeting
Relapsing Cryoglobulinemic Vasculitis Following Successful HCV Eradication by Interferon-Free Direct Acting Antivirals, an International Multicenter Study
Mohamed Tharwat Hegazy¹, Ahmed Fayed ¹, Tarek El Shabony ¹, Marcella Visentini ², David Saadoun ³, Patrice Cacoub ³ and Gaafar Ragab ¹, ¹Cairo University, Cairo, Egypt, Cairo, Egypt, ²Sapienza University of Rome, Rome, Italy, Rome, Italy, ³AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Paris, France
Background/Purpose: Interferon-free Direct Acting Antiviral (DAA) combinations proved to be effective for the treatment of HCV induced Cryoglobulinemic Vasculitis (HCV-Cryovas). Some reports showed relapses of…
Abstract Number: 2101 • 2019 ACR/ARP Annual Meeting
Hepatitis C Affects More Than Just the Liver: A Retrospective Chart Review on the Prevalence of Connective Tissue Diseases and Autoantibodies in Hepatitis C Virus Infections in an Academic Rheumatology Clinic
Matthew Malus¹, Ly-Elaine Pham ¹, Hrishikesh Samant ¹ and Mamatha Katikaneni ², ¹Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA, ²LSUHSC- Shreveport, Shreveport, LA
Background/Purpose: Chronic Hepatitis C virus infection (HCV) has been shown to be associated with connective tissue diseases (CTD). It has been hypothesized that HCV can…
Abstract Number: 829 • 2018 ACR/ARHP Annual Meeting
DNA Damage and Repair in Patients with Cryoglobulinemic Vasculitis Treated with Direct Anti-HCV Drugs
Mohamed Tharwat Hegazy¹, Walaa Allam², Mohamed A Hussein¹, Naguib Zoheir³, Luca Quartuccio⁴, Patrice Cacoub⁵, Wahid Doss⁶, Mona I. Ellawindi⁷, Mary Fawzy¹, Loïc Guillevin⁸, Ahmed El Ray⁹, Maissa El Said El Raziky^10,11, Magdy El Serafy⁶, Sherif El Khamisy^2,12 and Gaafar Ragab¹, ¹Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ²Center for Genomics, Zewail City of Science and Technology, Giza, Egypt, Giza, Egypt, ³Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁴Rheumatology Clinic, Academic Hospital S. M. della Misericordia, Medical Area Department, University of Udine, Italy, Udine, Italy, ⁵Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, Paris, France, ⁶Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁷Community Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁸Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, ⁹Theodor Bilharz Research Institute, Cairo, Egypt, Cairo, Egypt, ¹⁰Fatimid Cairo hospital, Cairo, Egypt, Cairo, Egypt, ¹¹Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, cairo, Egypt, ¹²Krebs Institute, University of Sheffield, Sheffield, S10 2TN, UK, Sheffield, United Kingdom
DNA Damage and Repair in Patients with Cryoglobulinemic Vasculitis Treated with Direct Anti-HCV Drugs Background/Purpose: Direct Acting Antiviral (DAA) agents were shown to be effective…
Abstract Number: 831 • 2018 ACR/ARHP Annual Meeting
No More HCV RNA in Serum and Cryoprecipitate in Patients with Persisting HCV-Cryoglobulinemia Vasculitis after Daa-Induced Sustained Virological Response
Patrice Cacoub¹, Eve Todesco², Pascale Ghillani-Dalbin³, Lucile Musset³ and David Saadoun⁴, ¹Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, Paris, France, ²Virology Pitie Salpetriere hospital, Paris, France, ³Immunobiology department Pitie Salpetriere Hospital, Paris, France, ⁴Sorbonne Universités, UPMC Univ Paris 06, UMR 7211, and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), F-75005, Paris, France; INSERM, UMR_S 959, F-75013, Paris, France; CNRS, FRE3632, F-75005, Paris, France; AP-HP, Groupe Hospitalier, Paris, France
No more HCV RNA in Serum and Cryoprecipitate in Patients with Persisting HCV-Cryoglobulinemia Vasculitis after DAA-induced Sustained Virological ResponseBackground/Purpose: In addition to high antiviral efficacy,…
Abstract Number: 1479 • 2018 ACR/ARHP Annual Meeting
The Predictive Utility of Anti-Cyclic Citrullinated Peptide Antibodies to Diagnose Rheumatoid Arthritis in Patients with Hepatitis C and Polyarthralgias
Divya Jayakumar^1,2, Xinliang Huang^1,2, Seth Eisen^1,2, Prabha Ranganathan^1,2 and Amy Joseph^2,3, ¹Rheumatology, VA St. Louis Health Care System, St Louis, MO, ²Rheumatology, Washington University School of Medicine, St Louis, MO, ³Rheumatology, VA St. Louis Health Care System, St. Louis, MO
Background/Purpose: Joint pain is a common extra-hepatic manifestation of chronic hepatitis C (HCV) infection. HCV infection is often associated with the presence of autoantibodies such…
Abstract Number: 281 • 2017 ACR/ARHP Annual Meeting
Direct Medical Costs Associated with the Extrahepatic Manifestations of Hepatitis C Virus Infection in France
Patrice Cacoub¹, Mathieu vautier², Anne-Claire Desbois³, David Saadoun⁴ and Zobair Younossi⁵, ¹Department of Internal Medicine and Clinical Immunology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France, ²Médecine Interne 1, Hôpital Pitié-Salpêtrière, Paris, France, ³Hôpital Pitié-Salpêtrière, Internal Medicine and Clinical Immunology, Paris, France, ⁴Sorbonne Universités, UPMC Univ Paris 06, UMR 7211, and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), F-75005, Paris, France; INSERM, UMR_S 959, F-75013, Paris, France; CNRS, FRE3632, F-75005, Paris, France; AP-HP, Groupe Hospitalier, Paris, France, ⁵Medicine, Inova Fairfax Hospital, Falls Church, Falls Church, VT
Background/Purpose: The economic impact of the extrahepatic manifestations (EHM) of hepatitis C virus (HCV) infection remains unknown for France. To estimate the prevalence of HCV-EHM…
Abstract Number: 894 • 2017 ACR/ARHP Annual Meeting
All Oral Interferon-Free Antivirals for Hepatitis C Virus Cryoglobulinemia Vasculitis: A Long Term Follow up Multicenter International Study
Patrice Cacoub¹, Si Nafa Si Ahmed², Yasmina FerFar³, SN Pol⁴, Dominique Thabut⁵, Christophe Hezode⁶, Laurent Albric⁷, Cloé Comarmond^8,9,10, Gafaar Ragab¹¹, Luca Quartuccio¹², Mohamed Hegazy¹³, Thierry Poynard⁵, Mathieu Resche-Rigon¹⁴ and David Saadoun¹⁵, ¹Department of Internal Medicine and Clinical Immunology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France, ²Hôpital Orléans, Orléans, France, ³Internal Medicine, Hopital Pitié-Salpetrière, Paris, France, ⁴Department of Hepatology, APHP, Hôpital Cochin, Paris, paris, France, ⁵Groupe Hospitalier Pitié-Salpétrière, Paris, France, ⁶Hôpital Henri Mondor, Creteil, France, ⁷Centre hospitalier universitaire Purpan, Purpan, France, ⁸Internal Medicine and Clinical Imunology, Referal Center for Autoimmune diseases, Internal Medicine and Clinical Imunology, Hôpital Pitié Salpétrière, Paris, France, ⁹DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France, ¹⁰Internal Medicine, Hôpital Pitié Salpétrière, Paris, France, ¹¹Cairo University, Cairo, Egypt, ¹²University Hospital "Santa Maria della Misericordia, Udine, Italy, ¹³Faculty of Medicine – Cairo University, Cairo, El Salvador, ¹⁴Hôpital Saint-Louis, Paris, France, ¹⁵Sorbonne Universités, UPMC Univ Paris 06, UMR 7211, and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), F-75005, Paris, France; INSERM, UMR_S 959, F-75013, Paris, France; CNRS, FRE3632, F-75005, Paris, France; AP-HP, Groupe Hospitalier, Paris, France
Background/Purpose: Interferon (IFN) containing regimens used for hepatitis C virus (HCV)-cryoglobulinemia vasculitis (CryoVas) are poorly effective and associated with important side effects. In small-size and…
Abstract Number: 1355 • 2017 ACR/ARHP Annual Meeting
14-3-3η: Useful for More Than the Diagnosis of Rheumatoid Arthritis?
Lisa Zickuhr¹, Maryam Pourpaki², Martha M. Brooks³ and Amy Joseph⁴, ¹Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, ²Rheumatology, Advocate Christ Medical Center at Chicago, Oak Lawn, IL, ³Rheumatology, St. Louis VA Medical Center, St. Louis, MO, ⁴Rheumatology, Veterans Administration Central Office, St. Louis, MO
Background/Purpose: Chronic hepatitis C virus (HCV) infection can masquerade as rheumatoid arthritis (RA). Distinguishing between the two is important because treatments differ. 14-3-3η has been…
Abstract Number: 2221 • 2017 ACR/ARHP Annual Meeting
Eradication of Hepatitis C Among US Veterans: Examination of Changes in Pain Severity and Prescription Opioid Use Following Treatment
Anand Kumthekar¹, Sarah Shull², Benjamin Morasco^3,4, Travis Lovejoy^3,4, Michael Chang² and Jennifer Barton³, ¹Rheumatology, Oregon Health & Science University, Portland, OR, ²Gastroenterology, VA Portland Health Care System, Portland, OR, ³VA Portland Health Care System, Portland, OR, ⁴Oregon Health & Science University, Portland, OR
Background/Purpose: Hepatitis C virus (HCV) is associated with chronic wide spread pain, fatigue, myalgia, arthritis, sicca symptoms and vasculitis. Data regarding prior interferon-based treatment of…
Abstract Number: 2741 • 2017 ACR/ARHP Annual Meeting
Rheumatoid Factor (RF) Levels Remain Persistently Elevated 24 Weeks after Interferon (INF) Free Direct Antiviral Agents (DAA) Therapy in the Majority of RF+ HCV Infected Persons
Corinne Kowal¹, Carey Shive^2,3, Elizabeth Zebrowski^4,5, Lenche Kostadinova^1,6, Brianna Fuller^1,6, Elane Reyes², Kelsey Rife⁴, Amy Hirsch⁴, Anita Compan⁴, Shyam Kottilil⁷, Yngve Falck-Ytter^6,8, Leonard H. Calabrese⁹, Donald Anthony^4,6,10,11 and Maya Mattar^6,12, ¹Department of Medicine, Louis Stokes VA Medical Center, Cleveland, OH, ²Department of Medicine and Pathology, Case Western Reserve University, Cleveland, OH, ³VA Geriartic Research and Education Clinical Center (GRECC), Louis Stokes VA Medical Center, Cleveland, OH, ⁴Louis Stokes VA Medical Center, Cleveland, OH, ⁵Department of Medicine, Case Western Reserve University, Cleveland, OH, ⁶Case Western Reserve University, Cleveland, OH, ⁷IHV Clinical Research Unit, University of Maryland, Baltimore,, Baltimore, MD, ⁸Internal Medicine/ Division of gastroenterology, Louis Stokes VA Medical Center, Cleveland, OH, ⁹Rheumatic & Immunologic Disease and Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, ¹⁰Division of Medicine and Pathology, Divisions of Infectious and Rheumatic diseases, University Hospitals Cleveland Medical Center, Cleveland, OH, ¹¹VA Geriatric Research and Education Clinical Center (GRECC), Cleveland, OH, ¹²Internal Medicine/ Division of Rheumatology, University Hospitals Cleveland Medical Center, Cleveland, OH
Background/Purpose: Cryoglobulinemic vasculitis (CV) is an extrahepatic manifestation of chronic HCV infection. It varies in severity from mild to life threatening. Some but not all…
Abstract Number: 17L • 2016 ACR/ARHP Annual Meeting
Sofosbuvir Plus Daclatasvir for Hepatitis C Virus Associated Cryoglobulinemia Vasculitis
David Saadoun¹, yasmina ferfar¹, AS Bouyer², laurent alric³, christophe hezode⁴, SN Si Ahmed⁵, L Musset⁶, Luc De Saint Martin Pernot⁷, SN Pol⁸, Dominique Larrey⁹, T Poynard¹⁰ and Patrice Cacoub², ¹Sorbonne Universités, UPMC Univ Paris 06, UMR 7211, and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), F-75005, Paris, France; Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Paris, France, ²Sorbonne Universités, UPMC Univ Paris 06, UMR 7211, and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), F-75005, Paris, France; Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, paris, France, ³Department of Internal Medicine-Digestive, Centre hospitalier universitaire Purpan, UMR 152 Toulouse 3 University, Toulouse, toulouse, France, ⁴Department of Hepatology, APHP, Hôpital Henri Mondor, Créteil, creteil, France, ⁵Department of Hepatology, Hôpital Orléans, Orléans, Orleans, France, ⁶Department of Immunology, UF d’Immunochimie et d’autoimmunité, APHP, Groupe Hospitalier Pitié-Salpétrière, Paris, France, paris, France, ⁷Department of internal medicine, CHRU Brest, Brest, France, ⁸Department of Hepatology, APHP, Hôpital Cochin, Paris, paris, France, ⁹Department of hepatology, CHRU Montpellier, France, montpellier, France, ¹⁰Department of Hepatology, APHP, Groupe Hospitalier Pitié-Salpétrière, Paris, paris, France

Background/Purpose: Hepatitis C virus (HCV) is the aetiological agent for most cases of cryoglobulinemia vasculitis. Interferon containing regimens are associated with important side effects and…
Abstract Number: 2977 • 2016 ACR/ARHP Annual Meeting
Treatment of Cryoglobulinemic Vasculitis with Sofosbuvir in Four Combination Protocols
Mohamed Tharwat Hegazy¹, Mohamed A Hussein¹, Luca Quartuccio², Mary Fawzy¹, Naguib Zoheir³, Mona I. Ellawindi⁴, Milena Bond², Cesare Mazzaro⁵, Ahmed El Ray⁶, Maissa El Said El Raziky^7,8, Magdy El Serafy⁹, Wahid Doss⁹, Patrice Cacoub¹⁰, Loïc Guillevin¹¹, Salvatore De Vita², Sherif El Khamisy¹² and Gaafar Ragab¹, ¹Internal Medicine, Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ²Rheumatology Clinic, DSMB, University of Udine, Udine, Italy, Udine, Italy, ³Clinical and Chemical Pathology Department, Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁴Community Medicine, Community Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁵Internal Medicine, Pordenone Hospital, Italy, pordenone, Italy, ⁶Theodor Bilharz Research Institute, Cairo, Egypt, Cairo, Egypt, ⁷Fatimid Cairo hospital, Cairo, Egypt, Cairo, Egypt, ⁸Tropical Medicine, Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, cairo, Egypt, ⁹Tropical Medicine, Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ¹⁰Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, ¹¹Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Paris, France, ¹²Zewail city of Science and Technology, Egypt, Giza, Egypt
Background/Purpose: Cryoglobulinemic Vasculitis (CV) is a systemic vasculitis affecting small and medium-sized vessels. Following emergence of direct acting antiviral drugs, which paved the way to…
Abstract Number: 1322 • 2016 ACR/ARHP Annual Meeting
Use of Biologics in Arthritis Patients with Hepatitis B and C ‏: A Multicentral Retrospective Case Series
Sultana Abdulaziz¹, Hessein Halabi², Mohammed Omair³, Suzan Attar⁴, Mohammed Shabrawishi⁵, Abdulwahab Neyazi⁶, Haneen Alnazzawi⁷, Noha Meraiani⁸ and Hani Almoallim⁹, ¹Dept of Medicine/Unit of Rheumatology, King Fahad Hospital, Jeddah, Saudi Arabia, ²Department of Medicine, King Faisal Specialist Hospital,, Jeddah, Saudi Arabia, ³Dept of Medicine, Div of Rheumatology, King Saud University, Riyadh, Saudi Arabia, ⁴Internal Medicine, FRCPC, ABIM, Professor in Medicine, Jeddah, Saudi Arabia, ⁵Department of Medicine, King Faisal Specialist Hospital, Jeddah, Saudi Arabia, ⁶Department of Medicine, King Abdullah Medical City, Jeddah, Saudi Arabia, ⁷King Faisal Specialist Hospital, JEDDAH, Saudi Arabia, ⁸Department of Medicine, National Guard Hospital, JEDDAH, Saudi Arabia, ⁹Department of Medicine, Umm Alqura University, Makkah, Saudi Arabia, Makkah, Saudi Arabia
Use of biologics in arthritis patients with Hepatitis B and C ‏: a multicentral retrospective case series Abstract Background/Purpose: Reactivation of viral hepatitis B…
Abstract Number: 1356 • 2015 ACR/ARHP Annual Meeting
Autoimmune Manifestations in Hepatitis C: A Single-Centered Experience
Azza Ali¹, Reshma Khan¹, Kirthi Lilley², Paul Naylor², Rajaie Namas¹ and Malini Venkatram¹, ¹Rheumatology, Wayne State University, Detroit, MI, ²Gastroenterology, Wayne State University, Detroit, MI
Background/Purpose: Hepatitis C infection (HCV) is a leading cause of chronic liver disease. It is associated with a plethora of autoimmune manifestations including clinical, serological…
Abstract Number: 1840 • 2015 ACR/ARHP Annual Meeting
How Good a Job Are We Rheumatologists Doing in Screening for Hepatitis B and C before Immuno-Suppressive/s Initiation in SLE?
Chandrahasa Annem¹, Joel A. Block² and Meenakshi Jolly³, ¹RHEUMATOLOGY, RUSH UNIVERSITY, CHICAGO, IL, ²Rush University Medical Center, Chicago, IL, ³Department of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Hepatitis B & C viral infections are widely prevalent and the potential of immunosuppressive medications (ISM) to exacerbate an underlying viral infection is well…

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