Abstracts tagged "gout"

Abstract Number: 143 • 2012 ACR/ARHP Annual Meeting
Proposed Gout Treatment Guidelines and Meeting Serum Urate and Flare Goals
Jasvinder A. Singh¹, David Hagerty², Chris Storgard³, Robert Mischler⁴ and Robert Morlock⁴, ¹Department of Medicine, University of Alabama, Tuscaloosa, AL, ²Medical, Ardea Bioscience, San Diego, CA, ³4939 Directors Place, Ardea Bioscience, San Diego, CA, ⁴Ardea Bioscience, San Diego, CA
Background/Purpose: Although gout is a relatively common condition, treatment is often not ideal with many patients continuing to experience multiple flares and some developing complications…
Abstract Number: 1903 • 2012 ACR/ARHP Annual Meeting
Oxidation of Urate to Allantoin by Myeloperoxidase in Gout
Lisa K. Stamp¹, Irada Khalilova², Mei Zhang¹, Rufus Turner² and Anthony Kettle², ¹Department of Medicine, University of Otago, Christchurch, Christchurch, New Zealand, ²Pathology, University of Otago, Christchurch, Christchurch, New Zealand
Background/Purpose : Hyperuricaemia is critical for the development of gout and may play a pivotal role in the pathophysiology of hypertension, metabolic syndrome, and cardiovascular…
Abstract Number: 816 • 2012 ACR/ARHP Annual Meeting
Glomerular Filtration Rate, Chronic Kidney Disease and Incidence of Physician Diagnosed Gout
Eswar Krishnan, Medicine, Standford University, Palo Alto, CA
Background/Purpose: The kidney is the major organ of urate excretion in humans. Yet, there are few studies that assess whether reduced glomerular filtration and/or kidney…
Abstract Number: 144 • 2012 ACR/ARHP Annual Meeting
Long-Term Safety of Canakinumab in Patients with Gouty Arthritis
Alexander So¹, Reike Alten², H. Ralph Schumacher³, Mark Bloch⁴, Thomas Bardin⁵, Markus R. John⁶, Gerhard Krammer⁶, Jan Michael Nebesky⁶, Aiyang Tao⁷ and Naomi Schlesinger⁸, ¹Rheumatology, CHUV, Univ of Lausanne, Lausanne, Switzerland, ²Charité Univ Medicine, Berlin, Germany, ³Department of Medicine, University of Pennsylvania and VA Medical Center, Philadelphia, PA, ⁴Holdsworth House Medical Practice, Sydney, Australia, ⁵Rheumatology, Hôpital Lariboisière, Paris, France, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁸UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: Gouty arthritis (GA) is a chronic inflammatory disease. Targeting the inflammatory pathway through IL-1β inhibition with canakinumab (CAN) may provide significant long-term benefits. CAN…
Abstract Number: 1904 • 2012 ACR/ARHP Annual Meeting
Patterns of Gout Treatment and Related Outcomes in US Community Rheumatology Practices: the Relation Between Gout Flares, Time in Treatment, Serum Uric Acid Level and Urate Lowering Therapy
Max I. Hamburger¹, John RP Tesser², John L. Skosey³, Allan H. Morton⁴ and Karl M. Kilgore⁵, ¹Rheumatology Associates, Melville, NY, ²AZ Arthritis Rheum Assoc, Paradise Valley, AZ, ³Illinois Bone & Joint Institut, Chicago, IL, ⁴Warren, MI, ⁵Cetus Group, LLC, Hunt Valley, MD
Background/Purpose: Study patterns of gout treatment and related outcomes in US community rheumatology practices, specifically the relation between likelihood and severity of gout flares, time…
Abstract Number: 817 • 2012 ACR/ARHP Annual Meeting
Feasibility of Using a Pharnacist-Based Gout Management Clinic to Improve Serum Uric Acid in Gout Patients an a Large Prepaid Health Plan
Robert D. Goldfien¹, Michele S. Ng², Goldie M. Yip², Alice Hwe², Alice Pressman³ and Andy L. Avins³, ¹Kaiser Permanente, Richmond, CA, ²Pharmacy, Kaiser Permanente, Oakland, CA, ³Division of Research, Kaiser Permanente, Oakland, CA
Background/Purpose: Effective treatment for recurrent gout has been hampered by a number of problems including outdated treatment approaches, a failure to treat to target, and…
Abstract Number: 145 • 2012 ACR/ARHP Annual Meeting
Prevalence of Non-Gout Arthritis in Patients with Gout: Not As Sparing As Previously Thought
Fernando Perez-Ruiz¹ and Ana M. Herrero-Beites², ¹Servicio de Reumatologia, Hospital Universitario Cruces, Baracaldo, Spain, ²Physical Medicine Division, Hospital de Gorliz, Gorliz, Spain
Background/Purpose: the presence of other chronic inflammatory disease has been historically and academically thought to be “protective” conditions for the development of gout. Objective: to…
Abstract Number: 1906 • 2012 ACR/ARHP Annual Meeting
Changes in Gout patient´s Clinical Profile in the Last Two Decades
Fernando Perez-Ruiz¹ and Ana M. Herrero-Beites², ¹Servicio de Reumatologia, Hospital Universitario Cruces, Baracaldo, Spain, ²Physical Medicine Division, Hospital de Gorliz, Gorliz, Spain
Background/Purpose: to assess whether changes in the clinical profile of gout are observed in a large cohort of gout patients over the last 20 years.…
Abstract Number: 741 • 2012 ACR/ARHP Annual Meeting
Increased Risk of Recurrent Gout Attacks During Hospitalization
Yuqing Zhang¹, Clara Chen², Hyon K. Choi³, Christine E. Chaisson², David J. Hunter⁴ and Tuhina Neogi⁵, ¹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ²Boston University School of Public Health, Boston, MA, ³Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁴Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁵Clinical Epidemiology, Boston Univ Schl of Med, Boston, MA
Background/Purpose: While anecdotal evidence suggests that risk of recurrent gout attack increases during hospitalization and gout is one of the most common reasons for in-patient…
Abstract Number: 101 • 2012 ACR/ARHP Annual Meeting
Kidney Function and the Risk of Incident Gout in A Population-Based Cohort of Adults: Atherosclerosis Risk in Communities Study
Mara McAdams DeMarco¹, Anna Kottgen², Andrew Law³, Janet W. Maynard⁴, Josef Coresh¹ and Alan N. Baer⁵, ¹Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ²Renal Division, University Hospital Freiburg, Freiburg, Germany, ³Epidemiology, Johns Hopkins, Baltimore, MD, ⁴Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: The 1-year cumulative incidence of gout in patients with new onset end stage renal disease is 5% and rises to 15% by 5 years,…

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