Abstracts tagged "giant cell arteritis"

Abstract Number: 1210 • 2019 ACR/ARP Annual Meeting
Utilization of a Multispecialty Team for the Diagnosis of Giant Cell Arteritis Reduces Patient Morbidity
Arash Hassantoufighi ¹, Rachel Lu-Do¹, Mamta Sherchan ¹, Christopher Collins ¹, Joshpaul Dhillon ² and Florina Constantinescu ¹, ¹MedStar Washington Hospital Center, Department of Rheumatology, Washington, DC, ²MedStar Washington Hospital Center, Department of Internal Medicine, Washington, DC
Background/Purpose: Giant Cell Arteritis (GCA) is an autoimmune vasculitis, most common in older adults with a peak incidence in the seventh decade. The diagnosis is…
Abstract Number: 2661 • 2019 ACR/ARP Annual Meeting
A Ten-Year Retrospective Review of Temporal Artery Biopsy Lengths in Alberta
Raymond Chu¹, Caylea Foster ², Mohsin Ali ³, Todd Chaba ¹, Jason Soo ¹, Alison Clifford ¹, Jan Willem Cohen Tervaert ¹ and Elaine Yacyshyn ¹, ¹University of Alberta, Edmonton, Canada, ²University of Calgary, Calgary, Canada, ³Harvard, Boston, MA
Background/Purpose: Temporal arteritis or giant cell arteritis (GCA) is a large vessel vasculitis that involves extracranial arteries. The historical gold standard for diagnosis is a…
Abstract Number: 2686 • 2019 ACR/ARP Annual Meeting
Real Life Data over 4 Years from a Fast Track GCA Pathway in Coventry
Shirish Dubey¹, Jonathan Pinnell ², Carl Tiivas ¹, Kaushik Chaudhuri ¹ and Purnima Mehta ¹, ¹University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, ²University Hospital North Staffordshire NHS Trust, Stoke, United Kingdom
Background/Purpose: University Hospital Coventry and Warwickshire NHS Trust (UHCW) established its one stop Fast Track Pathway (FTP) for Giant Cell Arteritis (GCA) in 2013. It…
Abstract Number: 1836 • 2019 ACR/ARP Annual Meeting
Clinical Outcomes of Patients with Giant Cell Arteritis with Polymyalgia Symptoms Only vs Cranial Symptoms Only Treated with Tocilizumab or Placebo in a Randomized Clinical Trial
Robert Spiera¹, Sebastian Unizony ², Min Bao ³, Yves Luder ⁴, Páris Sidiropoulos ³, Jian Han ³, Jinglan Pei ³ and John Stone ², ¹Hospital for Special Surgery, New York, NY, ²Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ³Genentech, South San Francisco, CA, ⁴F. Hoffmann-La Roche, Basel, Switzerland
Background/Purpose: GiACTA, a randomized, double-blind, placebo (PBO)–controlled study, demonstrated the efficacy and safety of tocilizumab (TCZ) in patients with giant cell arteritis (GCA).1 Growing evidence…
Abstract Number: 2662 • 2019 ACR/ARP Annual Meeting
Temporal Artery Biopsy Lengths in Alberta: Which Surgical Subspecialty Achieves Optimal Biopsy Lengths?
Raymond Chu¹, Caylea Foster ², Mohsin Ali ³, Todd Chaba ¹, Jason Soo ¹, Alison Clifford ¹, Jan Willem Cohen Tervaert ¹ and Elaine Yacyshyn ¹, ¹University of Alberta, Edmonton, Canada, ²University of Calgary, Calgary, Canada, ³Harvard, Boston, MA
Background/Purpose: Temporal arteritis or giant cell arteritis (GCA) is a large vessel vasculitis that involves extracranial arteries. Diagnosis requires a combination of clinical manifestations including…
Abstract Number: 2687 • 2019 ACR/ARP Annual Meeting
Clinicopathologic Associations in a Large International Cohort of Patients with Giant Cell Arteritis
Michael Putman¹, K Bates Gribbons ², Anthea Craven ³, Cristina Ponte ⁴, Joanna Robson ⁵, Ravi Suppiah ⁶, Richard Watts ⁷, Raashid Luqmani ³, Peter Merkel ⁸, Amy Archer ⁹ and Peter C. Grayson ¹⁰, ¹Northwestern University, Chicago, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ³University of Oxford, Oxford, United Kingdom, ⁴Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ⁵Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ⁶Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ⁷Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ⁸University of Pennsylvania, Pennsylvania, ⁹Northwestern, Chicago, ¹⁰National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: In addition to aiding in diagnosis, histopathologic findings from temporal artery biopsy (TAB) specimens in giant cell arteritis (GCA) may be valuable for their…
Abstract Number: 1837 • 2019 ACR/ARP Annual Meeting
Ustekinumab for the Treatment of Giant Cell Arteritis
Mark Matza¹, John Stone ¹, Ana Fernandes ¹ and Sebastian Unizony ¹, ¹Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA
Background/Purpose: Disease flare despite high cumulative glucocorticoid exposure is one of the hallmarks of giant cell arteritis (GCA). Tocilizumab is effective in controlling disease activity…
Abstract Number: 2664 • 2019 ACR/ARP Annual Meeting
Color Doppler Ultrasound for the Diagnosis of Giant Cell Arteritis in Montreal: A Canadian Single Center Experience
Jean-Paul Makhzoum¹, Meriem Belhocine ¹, Michelle Goulet ¹, Maxime Rheaume ¹, Tara Starnino ², Stephanie Ducharme-Benard ², Guillaume Febrer ³, Yves Troyanov ⁴, Nathalie Routhier ⁵, Rosalie-Selene Meunier ⁵, Isabelle Chagnon ⁵, Michel Laurier ⁵, Maggy Helou ⁵, Nathalie Morency ⁶ and Anne-Marie Mansour ¹, ¹Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ²Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, ³Vascular Surgery, Department of Surgery, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, ⁴Division of Rheumatology, Department of Medicine, Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁵Internal Medicine, Department of Medicine, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, ⁶Division of Rheumatology, Department of Medicine, Montreal, Canada
Background/Purpose: Giant Cell Arteritis (GCA) remains challenging to diagnose as false negative temporal artery biopsy (TAB) can occur. Color doppler ultrasonography (CDUS) of the temporal,…
Abstract Number: 2688 • 2019 ACR/ARP Annual Meeting
Comparisons of Strategies for Diagnostic Assessment in Giant Cell Arteritis: Results from an International Observational Cohort
K Bates Gribbons¹, Cristina Ponte ², Anthea Craven ³, Joanna Robson ⁴, Ravi Suppiah ⁵, Raashid Luqmani ³, Richard Watts ⁶, Peter Merkel ⁷ and Peter C. Grayson ⁸, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ³University of Oxford, Oxford, United Kingdom, ⁴Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ⁵Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ⁶Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ⁷University of Pennsylvania, Philadelphia, PA, ⁸National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Diagnostic assessment in giant cell arteritis (GCA) is rapidly changing as large-vessel (LV) involvement becomes increasingly recognized and non-invasive vascular imaging techniques become more…
Abstract Number: 1839 • 2019 ACR/ARP Annual Meeting
Different Patterns and Specific Outcomes of Large-Vessel Involvements in Giant Cell Arteritis
Hubert de BOYSSON¹, Eric LIOZON ², Olivier ESPITIA ³, Aurélie DAUMAS ⁴, Mathieu VAUTIER ⁵, Marc LAMBERT ⁶, Jean-Jacques PARIENTI ⁷, Alain MANRIQUE ⁷, David Saadoun ⁸, Kim Heang Ly ², Christian Agard ⁹ and Achille Aouba ¹⁰, ¹University Hospital of Caen, Caen, France, ²Limoges University Hospital, Limoges, France, ³Nantes University Hospital, Nantes, France, ⁴Marseille AP-HM, Marseille, France, ⁵Paris - Pitié salpétrière, Paris, France, ⁶Lille University Hospital, Lille, France, ⁷Caen University Hospital, Caen, France, ⁸AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Paris, France, ⁹CHU Nantes, Nantes, France, ¹⁰CHU Caen, Caen, France
Background/Purpose: Large-vessel involvements (LVI) in giant-cell arteritis (GCA) include different clinical and imaging patterns that are often pooled together in the published cohorts under the…
Abstract Number: 2665 • 2019 ACR/ARP Annual Meeting
Clinical Outcomes of Patients with Giant Cell Arteritis and Polymyalgia Rheumatica Symptoms Treated with Tocilizumab in Routine Clinical Practice
Sebastian Unizony¹, Robert Spiera ², Jinglan Pei ³, Páris Sidiropoulos ³, Jennie Best ⁴ and John Stone ¹, ¹Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ²Hospital for Special Surgery, New York, NY, ³Genentech, South San Francisco, CA, ⁴Genentech, Inc., South San Francisco, CA
Background/Purpose: Approximately 50% of patients with giant cell arteritis (GCA) also have polymyalgia rheumatica (PMR) symptoms.1 The purpose of this study was to determine whether…
Abstract Number: 2690 • 2019 ACR/ARP Annual Meeting
Fast Track Clinic (FTC) for Giant Cell Arteritis (GCA) – the United States Experience
Ingeborg Sacksen ¹, Elizabeth Jernberg ¹, Scott Pollock ², Jean Liew ³, Sarah Chung ², R Eugene Zierler ³ and Alison Bays², ¹University of Washington Division of Rheumatology, Seattle, ²University of Washington Division of Rheumatology, Seattle, WA, ³University of Washington, Seattle, WA
Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis in adults and if untreated, may result in visual impairment. Although the gold…
Abstract Number: 1841 • 2019 ACR/ARP Annual Meeting
Resolution of Vascular Inflammation in Patients with Giant Cell Arteritis Receiving Glucocorticoids, Methotrexate or Tocilizumab Treatment: Data from the Italian/German RIGA Study
Verena Schönau ¹, Jessica Roth ¹, Koray Tascilar ², Jürgen Rech ³, Daniela Schmidt ⁴, Torsten Kuwert ⁴, Filippo Crescentini ⁵, Luigi Boiardi ⁶, Massimiliano Casali ⁷, Annibale Versari ⁸, Giulia Pazzola ⁵, Georg Schett ⁹, Carlo Salvarani ¹⁰ and Francesco Muratore¹¹, ¹Rheumatology Unit, University of Erlangen, Erlangen, Germany, ²Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Bayern, Germany, ³Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany, ⁴Nuclear Medicine Unit, University of Erlangen, Erlangen, Germany, ⁵Rheumatology Unit, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁶Division of Rheumatology, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁷Azienda USL-IRCCS di Reggio Emilia, REGGIO EMILIA, Italy, ⁸Nuclear Medicine Unit, Azienda Unità Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Emilia-Romagna, Italy, ⁹Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, ¹⁰Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, ¹¹Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy
Background/Purpose: 18F-FDG-PET/CT is a sensitive and comprehensive technique to diagnose giant cell arteritis (GCA). This technique may be also very useful to test whether vascular…
Abstract Number: 2669 • 2019 ACR/ARP Annual Meeting
Survival Trends in Giant Cell Arteritis: A Population-based Cohort Study
Thomas Garvey¹, Cynthia Crowson ¹, Matthew Koster ², Eric Matteson ³ and Kenneth Warrington ², ¹Mayo Clinic Rochester, Rochester, ²Mayo Clinic Rochester, Rochester, MN, ³Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, Rochester
Background/Purpose: To investigate survival trends in patients with giant cell arteritis (GCA) diagnosed over a 60-year period.Methods: We assembled a population-based incidence cohort of patients…
Abstract Number: 2691 • 2019 ACR/ARP Annual Meeting
Treatment Patterns, Disease Burden and Outcomes in Patients with Giant Cell Arteritis and Polymyalgia Rheumatica
Gary Craig¹, Keith Knapp ², Bob Salim ³, Shalini Mohan ⁴ and Margaret Michalska ⁴, ¹Arthritis Northwest; Discus Analytics, Spokane, WA, ²Discus Analytics, Spokane, WA, ³Axio Research, Seattle, WA, ⁴Genentech, Inc., South San Francisco, CA
Background/Purpose: For patients with giant cell arteritis (GCA) and/or polymyalgia rheumatica (PMR), glucocorticoids are the mainstay of treatment. However, due to the chronic nature of…

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