Abstracts tagged "giant cell arteritis"

Abstract Number: 2260 • 2019 ACR/ARP Annual Meeting
Patients’ Journeys Through Giant Cell Arteritis: A Qualitative Study
Jennie Best¹, Ivan Nunez ², Kristina Woodburn ², Abby Breyer ², Mike Conway ² and Margaret Michalska ¹, ¹Genentech, Inc., South San Francisco, CA, ²Azul Seven, Minneapolis, MN
Background/Purpose: Diagnosis of giant cell arteritis (GCA) is difficult due to multiple presenting symptoms, and access to care may be delayed because often multiple providers…
Abstract Number: 2670 • 2019 ACR/ARP Annual Meeting
Giant Cell Arteritis with Intracranial Vasculitis: A Case Series
Catalina Sanchez-Alvarez¹, Alexander Hawkins ¹, Matthew Koster ², Vance T. Lehman ³, Cynthia Crowson ¹ and Kenneth Warrington ², ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic Rochester, Rochester, MN, ³Mayo Clinic, Rochester
Background/Purpose: Giant cell arteritis (GCA) is a large vessel vasculitis that primarily affects the aorta and its branches. Extracranial branches of the carotid artery are…
Abstract Number: 2692 • 2019 ACR/ARP Annual Meeting
Coronary Artery Disease in a Population-Based Cohort of Biopsy-Proven Giant Cell Arteritis in Southern Sweden
Pavlos Stamatis¹, Moman Mohammad ¹, Peter Merkel ², Martin Englund ³, Carl Turesson ⁴, David Erlinge ¹ and Aladdin Mohammad ¹, ¹Lund University, Lund, Skane Lan, Sweden, ²University of Pennsylvania, Philadelphia, PA, ³Lund University, Lund, Sweden, ⁴Lund University, Malmö, Sweden
Background/Purpose: The aim of this study was to estimate the incidence rate and prevalence of coronary artery diseases (CAD) in patients with temporal artery positive…
Abstract Number: 2649 • 2019 ACR/ARP Annual Meeting
Comparison of Biopsy Proven Giant Cell Arteritis in North America and South Europe: A Population-Based Study
Francesco Muratore¹, Cynthia Crowson ², Luigi Boiardi ³, Ambra Pinelli ⁴, Matthew Koster ⁵, Giovanna Restuccia ¹, Tanaz Kermani ⁶, Eric Matteson ⁷, Carlo Salvarani ⁸ and Kenneth Warrington ⁵, ¹Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ²Mayo Clinic Rochester, Rochester, ³Division of Rheumatology, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁴Division of Rheumatology, University of Modena and Reggio Emilia, Reggio Emilia, Italy, ⁵Mayo Clinic Rochester, Rochester, MN, ⁶University of California Los Angeles, Los Angeles, CA, ⁷Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, Rochester, ⁸Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: To compare clinical characteristics, treatment, long-term follow-up and prognosis of two population-based cohorts of patients with biopsy-proven giant cell arteritis (GCA) from North America…
Abstract Number: 2673 • 2019 ACR/ARP Annual Meeting
Presentation and Management of Giant Cell Arteritis in a Real-World Setting (Artemis Study)
Alfred Mahr¹, Eric Hachulla ², Hubert de BOYSSON ³, Nassim Guerroui ⁴, Emmanuel Héron ⁵, Stéphane Vinzio ⁶, Jonathan Broner ⁷, François-Xavier Lapebie ⁸, Martin Michaud ⁹, Laurent Sailler ⁸, Thierry Zenone ¹⁰, Mohamed Djerad ¹¹, Mathieu Jouvray ¹², Emilie Shipley ¹³, Nathalie Tieulie ¹⁴, Isabelle Idier ¹⁵, Marc Paccalin ¹⁶ and Valérie Devauchelle Pensec ¹⁷, ¹Hospital Saint-Louis, University Paris Diderot, Paris, France, ²Dept. of Internal Medicine and Clinical Immunology, Hôpital Claude Huriez, University of Lille, Lille, France, Lille, France, ³University Hospital of Caen, Caen, France, ⁴European Hospital of Marseille, Marseille, France, ⁵Quinze-Vingt Hospital, Paris, France, ⁶GHM Grenoble, Grenoble, France, ⁷University Hospital of Nîmes, Nîmes, France, ⁸University Hospital of Toulouse, Toulouse, France, ⁹Joseph Ducuing Hospital, Toulouse, France, ¹⁰Hospital of Valence, Valence, France, ¹¹Hospital of Nevers, Nevers, France, ¹²Hospital of Arras, Arras, France, ¹³Hospital of Dax, Dax, France, ¹⁴University Hospital of Nice, Nice, France, ¹⁵Chugai Pharma France, Paris La Défense, France, ¹⁶University Hospital of Poitiers, Poitiers, France, ¹⁷University Hospital of Brest, Brest, France
Background/Purpose: We have few real-world data on the natural history and care of patients with giant cell arteritis (GCA). The objective of this observational study…
Abstract Number: 2918 • 2019 ACR/ARP Annual Meeting
Metabolic Signatures of Pathogenic T Cells in Medium and Large Vessel Vasculitis
Mitsuhiro Akiyama ¹, Hui Zhang ¹, Ryu Watanabe ¹, Toshihisa Maeda ², Gerald Berry ¹, Jorg Goronzy ¹ and Cornelia Weyand¹, ¹Stanford University, Stanford, CA, ²Matsubara Mayflower Hospital, Kobe, Japan
Background/Purpose: Giant cell arteritis (GCA) is an autoimmune vasculitis that causes aortic arch syndrome, blindnesss, and stroke. Embedded in granulomatous infiltrates, CD4 T cells persist…
Abstract Number: 2650 • 2019 ACR/ARP Annual Meeting
Predictors of Relapse in Giant Cell Arteritis: Data from an International Collaboration
Laure Delaval ¹, Raphael Porcher ², Kenneth Warrington ³, Francesco Muratore ⁴, Cynthia Crowson ⁵, Daniel Blockmans ⁶, Christian Agard ⁷, Alexis Régent ⁸, Maxime Samson ⁹, Loic Guillevin ⁸, Carlo Salvarani ¹⁰ and Benjamin Terrier⁸, ¹Department of Internal Medicine, Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, Paris, France, Paris, France, ²Hotel Dieu Hospital, Paris, France, ³Mayo Clinic Rochester, Rochester, MN, ⁴Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁵Mayo Clinic Rochester, Rochester, ⁶Department of General Internal Medicine, University Hospitals Gasthuisberg, Leuven, Belgium, ⁷CHU Nantes, Nantes, France, ⁸National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France, ⁹Service de Médecine Interne et Immunologie Clinique, CHU Dijon Bourgogne, Hôpital François Mitterrand, Dijon ; Université Bourgogne-Franche Comté, INSERM, EFS BFC, UMR1098, F-21000 Dijon, Dijon, France, ¹⁰Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: Roughly half of giant-cell arteritis (GCA) patients taking only glucocorticoids (GCs) relapse. The relapse rate seems to reflect, in part, the duration of GC intake, more…
Abstract Number: 2675 • 2019 ACR/ARP Annual Meeting
Risk of Potential Glucocorticoid-Related Adverse Events in Patients with Giant Cell Arteritis: Results from a US-based Electronic Health Records Database
Jennie Best¹, Amanda M. Kong ², Oth Tran ² and Margaret Michalska ¹, ¹Genentech, Inc., South San Francisco, CA, ²IBM Watson Health, Cambridge, MA
Background/Purpose: Oral glucocorticoids (OGC) have been the mainstay of treatment for giant cell arteritis (GCA). However, OGCs are associated with several adverse events (AEs). The…
Abstract Number: 2920 • 2019 ACR/ARP Annual Meeting
Comparison of Arterial Patterns of Disease in Takayasu’s Arteritis and Giant Cell Arteritis
K Bates Gribbons¹, Cristina Ponte ², Anthea Craven ³, David Cuthbertson ⁴, Simon Carette ⁵, Gary S. Hoffman ⁶, Nader A. Khalidi ⁷, Curry L. Koening ⁸, Carol Langford ⁹, Kathleen Maksimowicz-McKinnon ¹⁰, Carol A. McAlear ¹¹, Paul Monach ¹², Larry Moreland ¹³, Christian Pagnoux ¹⁴, Kaitlin Quinn ¹⁵, Joanna Robson ¹⁶, Philip Seo ¹⁷, Antoine Sreih ¹⁸, Ravi Suppiah ¹⁹, Kenneth Warrington ²⁰, Steven Ytterberg ²¹, Raashid Luqmani ³, Richard Watts ²², Peter Merkel ¹⁸ and Peter C. Grayson ²³, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ³University of Oxford, Oxford, United Kingdom, ⁴University of South Florida, Tampa, FL, ⁵Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, Canada, ⁶Cleveland Clinic Foundation, Cleveland, OH, ⁷McMaster University, Hamilton, ON, Canada, ⁸University of Utah Hospital, Salt Lake City, UT, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Henry Ford Hospital, Wayne State University, Detroit, MI, ¹¹University of Pennsylvania - VCRC Project Manager, Philadelphia, PA, ¹²Brigham and Women's Hospital, Boston, MA, ¹³University of Pittsburgh, PITTSBURGH, PA, ¹⁴Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, ¹⁵Georgetown University Hospital/National Institutes of Health, Washington, DC, ¹⁶Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ¹⁷Johns Hopkins Medicine, Baltimore, MD, ¹⁸University of Pennsylvania, Philadelphia, PA, ¹⁹Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ²⁰Mayo Clinic Rochester, Rochester, MN, ²¹Mayo Clinic College of Medicine, Rochester, MN, ²²Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ²³National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Current classification criteria differentiate between Takayasu’s arteritis (TAK) and giant cell arteritis (GCA), the two most common forms of large-vessel vasculitis, based primarily on…
Abstract Number: 2651 • 2019 ACR/ARP Annual Meeting
Are There Phenotypic Overlaps Between Giant Cell Arteritis Subgroups?
Berkan Armagan ¹, Abdullah Yildirim ², Alper Sarı ³, Bayram Farisoğulları ³, Emre Bilgin ³, Levent Kilic ⁴, Umut Kalyoncu ⁵, Şule Apras Bilgen ⁴ and Omer Karadag⁶, ¹Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, ²Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey, ³Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, ⁴Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ⁵Hacettepe University Department of Rheumatology, Ankara, Turkey, ⁶Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey
Background/Purpose: In parallel to the improvements in imaging, increasing data is accumulated regarding phenotypes of primary vasculitides. Giant cell arteritis (GCA) is a large vessel…
Abstract Number: 2676 • 2019 ACR/ARP Annual Meeting
Cardiovascular Treatment and the Incidence of Giant Cell Arteritis (GCA) – a Population-Based Case-Control Study
Aladdin Mohammad¹, Pavlos Stamatis ¹ and Aleksandra Turkiewicz ², ¹Lund University, Lund, Skane Lan, Sweden, ²Lund University, Lund, Sweden
Background/Purpose: The aetiology of giant cell arteritis (GCA) is largely unknown. We aimed to evaluate ACE-inhibitors (ACE-i), angiotensin II receptor blockers (ARBs), beta-blocking agents, calcium…
Abstract Number: 2921 • 2019 ACR/ARP Annual Meeting
High Resolution 3D Fast Spin-Echo T1 Black-Blood Imaging for the Diagnosis of Giant Cell Arteritis
Christine rodriguez ¹, Wagih Ben Hassen ¹, Pierre Seners ², Catherine Oppenheim ¹ and Alexis Régent³, ¹Département d’imagerie, pôle Neuro Sainte Anne, GHT Paris – Psychiatrie & Neurosciences, 1 rue Cabanis, 75014 Paris, Paris, Ile-de-France, France, ²Service de neurologie, pôle Neuro Sainte Anne, GHT Paris – Psychiatrie & Neurosciences, 1 rue Cabanis, 75014 Paris, Paris, Ile-de-France, France, ³National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France
Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis of large arteries affecting people older than 50 years. Temporal artery biopsy (TAB)…
Abstract Number: 2652 • 2019 ACR/ARP Annual Meeting
Comparison Between Transmural and Isolated Periadventitial And/or Adventitial Inflammation at Temporal Artery Biopsy: A Single Center Cohort of Biopsy-Positive GCA with Long Term Follow-up
Elena Galli¹, Francesco Muratore ², Luigi Boiardi ³, Alberto Cavazza ⁴, Giovanna Restuccia ², Luca Cimino ⁵ and Carlo Salvarani ⁶, ¹Division of Rheumatology, University of Modena and Reggio Emilia, Modena, Italy, ²Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ³Division of Rheumatology, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁴Pathology Unit, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁵Ophthalmology Unit, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁶Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: Temporal artery biopsy (TAB) showing transmural inflammation is considered the gold standard for the diagnosis of giant cell arteritis (GCA). In some cases, inflammation…
Abstract Number: 2677 • 2019 ACR/ARP Annual Meeting
Healthcare Resources Utilization in Giant Cell Arteritis – a Population-Based Study
Aladdin Mohammad¹, Aleksandra Turkiewicz ², Pavlos Stamatis ¹, Carl Turesson ³, Martin Englund ² and Ali Kiadaliri ², ¹Lund University, Lund, Skane Lan, Sweden, ²Lund University, Lund, Sweden, ³Lund University, Malmö, Sweden
Background/Purpose: To study the healthcare resource utilization (HRU) in patients with giant cell arteritis (GCA) compared with the background population in southern Sweden.Methods: The study…
Abstract Number: 2923 • 2019 ACR/ARP Annual Meeting
Clinical Subsets in Giant Cell Arteritis
K Bates Gribbons¹, Cristina Ponte ², Anthea Craven ³, Joanna Robson ⁴, Ravi Suppiah ⁵, Richard Watts ⁶, Raashid Luqmani ³, Peter Merkel ⁷ and Peter C. Grayson ⁸, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ³University of Oxford, Oxford, United Kingdom, ⁴Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ⁵Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ⁶Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ⁷University of Pennsylvania, Philadelphia, PA, ⁸National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Giant cell arteritis (GCA) is a clinically heterogeneous disease. Disease subsets based upon cranial versus extracranial artery involvement have been proposed. The study objective…

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