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Abstracts tagged "giant cell arteritis"

  • Abstract Number: 1406 • ACR Convergence 2021

    Incidence and General Clinical Features of Giant Cell Arteritis in the ARTESER Multicenter Study

    Jesús T. Sánchez-Costa1, Rafael B. Melero-González2, Elisa Fernández-Fernández3, María T. Silva-Diaz4, Joaquín M. Belzunegui5, Clara Moriano6, Julio Sánchez7, Judit Lluch8, Itziar Calvo9, Vicente Aldasoro10, Lydia Abasolo11, Javier Loricera12, Alberto Ruíz-Román13, Santos Castañeda14, Patricia Moya15, María J. Garcia-Villanueva16, Vanessa A. Navarro-Angeles17, Carles Galisteo18, Anne Riveros-Frutos19, Jose A. Román-Ivorra20, Selene Labrada-Arrabal21, Margarida Vasques-Rocha22, Carlota L. Iñiguez-Ubiaga23, María García-González24, Clara Molina-Almela25, María Alcalde-Villar26, Antonio Juan Mas27, Eugenio De Miguel28, Javier Narvaez29, Miguel Ángel gonzalez-Gay30, Noemí Garrido-Puñal13, Paula V. Estrada-Alarcon17 and Ricardo Blanco31, 1Research unit, Spanish Society of Rheumatology, Madrid, Spain, 2Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 3Rheumatology department, La Paz University Hospital, Madrid, Spain, 4Complejo Hospitalario Universitario de La Coruña, Coruña, Spain, 5Hospital Universitario Donostia, Donostia-San Sebasti, Spain, 6Hospital Universitario de León, León, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitari Bellvitge, Hospitalet de Llobregat, Spain, 9Basurto University Hospital, Bilbao, Spain, 10Complejo Hospitalario de Navarra, Pamplona, Spain, 11Rheumatology Department, Hospital Clínico San Carlos, Madrid, Spain, 12Hospital Universitario Marqués de Valdecilla, Santander, Spain, 13Hospital Universitario Virgen del Rocío, Sevilla, Spain, 14Hospital Universitario de la Princesa, Madrid, Spain, 15Hospital Sant Pau, Barcelona, Spain, 16Rheumatology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain, 17Hospital de Sant Joan Despí Moisès Broggi. Sant Joan Despí, Barcelona, Spain, 18Hospital Universitari Parc Tauli, Saadell, Spain, 19Hospital Germans Trias i Pujol, Badalona, Spain, 20Hospital Universitari i Politècnic La Fe, Valencia, Spain, 21Hospital del Mar, Barcelona, Spain, 22Hospital Universitario Araba, Vitoria-Gasteiz, Spain, 23Hospital Universitario Lucus Augusti, Lugo, Spain, 24Hospital Universitario de Canarias, La Laguna, Spain, 25Rheumatology Department, Consorci Hospital General Universitari de Valencia, Valencia, Spain, 26Hospital Universitario Severo Ochoa, Leganés, Spain, 27Rheumatology Department, Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, 28Hospital Universitario La Paz, Madrid, Spain, 29Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 30Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 31Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Epidemiological information on Giant Cell Arteritis (GCA) comes mainly from the Scandinavian countries of northern Europe, which show a higher incidence than the countries…
  • Abstract Number: 1867 • ACR Convergence 2021

    Investigating Adenosine Deaminase 2 Activity in Large Vessel Vasculitis

    Andrew Porter1, Robert Maughan1, Charis Pericleous1, Allan Kiprianos1, Hyuk Jee2, Pui Lee2, Taryn Youngstein1 and Justin Mason1, 1Imperial College London, London, United Kingdom, 2Boston Children's Hospital, Newton, MA

    Background/Purpose: Deficiency of adenosine deaminase 2 (DADA2) leads to a broad phenotype that in some resembles polyarteritis nodosa with fever and rash, but in others…
  • Abstract Number: 0652 • ACR Convergence 2021

    Application of a GCA Probability Score to Patients Referred to a GCA Fast Track Clinic

    Mmoloki Mathake1, Julia Murdoch2, Andrew Taylor3, Jean-Louis deSousa2, Kathy Jao2, Rachel Li2 and Helen Keen4, 1Fiona Stanley Hospital, Beckenham, Australia, 2Royal Perth Hospital, Perth, Australia, 3Fiona Stanley Hospital, Murdoch, Australia, 4Fiona Stanley Hospital, Perth, Australia

    Background/Purpose: Giant cell arteritis (GCA) is the most common large vessel vasculitis, and may be associated with irreversible blindness(1). It is therefore essential to make…
  • Abstract Number: 1408 • ACR Convergence 2021

    Treatment of Giant Cell Arteritis in the ARTESER Multicenter Study of 1675 Patients

    Jesús T. Sánchez-Costa1, Iñigo Hernández-Rodríguez2, Elisa Fernández-Fernández3, María T. Silva-Diaz4, Jesús A. Valero-Jaimes5, Ismael González-Fernández6, Julio Sánchez7, Judit Lluch8, Eva Galindez-Agirregoikoa9, Javier Mendizábal-Mateos10, Pia M. Lois Bermejo11, Javier Loricera12, Alejandro Muñoz13, Cristina Valero-Martínez14, Patricia Moya15, Carmen Larena-Grijalba16, Vanessa A. Navarro-Angeles17, Joan Calvet-Fontova18, Ivette Casafont19, Francisco Ortiz-Sanjuán20, Selene Labrada-Arrabal21, Jaime Calvo-Alén22, Carlota L. Iñiguez-Ubiaga23, Vanesa Hernández24, Cristina Campos-Fernández25, María Alcalde-Villar26, Antonio Juan-Mas27, Eugenio De Miguel28, Javier Narvaez29, Miguel Ángel gonzalez-Gay30, Noemí Garrido-Puñal31, Paula V. Estrada-Alarcon17 and Ricardo Blanco32, 1Spanish Society of Rheumatology, Madrid, Spain, 2Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 3Rheumatology department, La Paz University Hospital, Madrid, Spain, 4Complejo Hospitalario Universitario de La Coruña, Coruña, Spain, 5Hospital Universitario Donostia, Donostia-San Sebasti, Spain, 6Hospital Universitario de León, León, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitari Bellvitge, Hospitalet de Llobregat, Spain, 9Hospital Universitario de Basurto, Bilbao, Spain, 10H. Navarra, Navarra, Spain, 11Rheumatology Department, Hospital Clínico San Carlos, Madrid, Spain, 12Hospital Universitario Marqués de Valdecilla, Santander, Spain, 13Hospital Universitario Virgen del Rocío, Sevial, Spain, 14Hospital Universitario de La Princesa, Madrid, Spain, 15Hospital Sant Pau, Barcelona, Spain, 16Rheumatology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain, 17Hospital de Sant Joan Despí Moisès Broggi. Sant Joan Despí, Barcelona, Spain, 18Hospital Universitari Parc Tauli, Sabadell, Spain, 19Hospital Universitari Germans Trias i Pujol, Barcelona, Badalona, Spain, 20H. La Fe, Valencia, Spain, 21Hospital del Mar, Barcelona, Spain, 22Rheumatology Department, Hospital Universitario Araba, Vitoria-Gasteiz, Spain, 23Hospital Universitario Lucus Augusti, Lugo, Spain, 24Rheumatology Department, Hospital Universitario de Canarias, La Laguna, Spain, 25Consorci Hospital General Universitari de Valencia, Valencia, Spain, 26Hospital Universitario Severo Ochoa, Leganés, Spain, 27Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, 28Hospital Universitario La Paz, Madrid, Spain, 29Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 30Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 31Hospital Universitario Virgen del Rocío, Sevilla, Spain, 32Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Glucocorticoids (GC) are the mainstay therapy in Giant Cell Arteritis (GCA), initially at high doses (40-60 mg/day) followed by gradual glucocorticoid tapering. This treatment,…
  • Abstract Number: 1882 • ACR Convergence 2021

    Clinical Characteristics and Reliability of a Self-Reported Diagnosis of Large-Vessel Vasculitis

    Tannaz Kermani1, Jason Springer2, Dianne Shaw3, Kalen Young4, Cristina Burroughs5 and Peter Merkel6, 1University of California Los Angeles, Los Angeles, CA, 2Vanderbilt University Medical Center, Franklin, TN, 3Vasculitis Foundation, Chapel Hill, NC, 4Vasculitis Foundation, Kansas City, MO, 5Health Informatics Institute, Tampa, FL, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: To compare the clinical characteristics and determine the reliability of a self-reported diagnosis of giant cell arteritis (GCA) or Takayasu’s arteritis (TAK) from an…
  • Abstract Number: 0952 • ACR Convergence 2021

    Outcomes of COVID-19 Infection in Patients with Primary Systemic Vasculitis and Polymyalgia Rheumatica: Results from the COVID-19 Global Rheumatology Alliance Physician Registry

    Sebastian Sattui1, Richard Conway2, Michael Putman3, Andrea Seet4, Kaley Beins5, Catherine Hill6, David Liew7, Sarah Mackie8, Puja Mehta9, Lorna Neill10, Gimena Gomez11, Maria Salinas12, Federico Maldonado13, Henrique Moriz14, Samia Studart15, NAFICE ARAUJO16, Ann Knight17, Davide Rozza18, Luca Quartuccio19, Maxime Samson20, Stephane Bally21, Alexandre Maria22, Pascal Chazerain23, Rebecca Hasseli24, Ulf Müller-Ladner25, Bimba Franziska Hoyer26, Reinhard Voll27, Rita Pinheiro Torres28, Mariana Luis29, Sandra Lúcia Ribeiro30, Samar Al Emadi31, Jeffrey Sparks32, Tiffany Hsu33, Kristin D'Silva34, Naomi Patel34, Leanna Wise35, Emily Gilbert36, Maria Valenzuela-Almada37, Ali Duarte-Garcia38, Manuel Ugarte-Gil39, Emily Sirotich40, Jean Liew41, Jonathan Hausmann42, Paul Sufka43, Suleman Bhana44, Rebecca Grainger45, Wendy Costello46, Lindsay Jacobsohn47, Zara Izadi4, Anja Strangfeld48, Elsa Frazão Mateus49, Kimme Hyrich50, Laure Gossec51, Loreto Carmona52, Saskia Lawson-Tovey50, Lianne Kearsley-Fleet53, Martin Schaefer54, Milena Gianfrancesco4, Pedro Machado55, Zachary Wallace34, Jinoos Yazdany4 and Philip Robinson56, 1Hospital for Special Surgery, New York, NY, 2St. James's University Hospital, Dublin, Ireland, 3Medical College of Wisconsin, Brookfield, WI, 4University of California San Francisco, San Francisco, CA, 5Vasculitis Foundation, Kansas City, MO, 6Queen Elizabeth Hospital, Woodville, Australia, 7Austin Health, Heidelberg, Australia, 8School of Medicine, University of Leeds, Leeds, United Kingdom, 9University College London, London, United Kingdom, 10PMR GCA Scotland, Perth, United Kingdom, 11Research Unit Argentine Society of Rheumatology, Buenos Aires, Argentina, 12Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 13Sanatorio Güemes, Buenos Aires, Argentina, 14Hospital das Clinicas, Universidade Federal de Pernambuco, Pernambuco, Brazil, 15HOSPITAL GERAL DE FORTALEZA, Fortaleza, Brazil, 16Instituto de ASsistencia Medica ao Servidor Publico Estadual de São Paulo, São Paulo, Brazil, 17Rheumatology, Institute of Medical Sciences, Uppsala University, Uppsala, Sweden, 18Epidemiology Research Unit, Italian Society of Rheumatology, Rome, Italy, 19Clinical Rheumatology, Department of Medicine, University of Udine, Udine, Italy, 20CHU Dijon Bourgogne, Hpital Franois Mitterrand, Dijon, Dijon, France, 21Nephrology and Dialysis Service, Metropole Savoie Hospital Center, Chambery, France, 22Department of Internal Medicine and Multiorganic Diseases, Saint-Eloi University Hospital of Montpellier, Montpellier, France, 23Department of Rheumatology and Internal Medicine, Diaconesses Croix Saint Simon Hospital, Paris, France, 24Department of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus Liebig University Giessen, Bad Nauheim, Germany., Bad Nauheim, Germany, 25JLU Giessen, Campus Kerckhoff, Dept. Rheum & Clin Immunol, Bad Nauheim, Germany, 26Universittsklinikum Schleswig-Holstein, Kiel, Germany, 27Department of Rheumatology and Clinical Immunology, University Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany, 28Rheumatology Service, Egas Moniz Hospital, Lisboa Occidental Hospital Centre, Lisbon, Portugal, 29Department of Rheumatology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portuga, Coimbra, Portugal, 30Universidade Federal do Amazonas, Amazonas, Brazil, 31Hamad medical corporation, Doha, Qatar, 32Brigham and Women's Hospital, Boston, MA, 33Brigham and Women's Hospital, Jamaica Plain, MA, 34Massachusetts General Hospital, Boston, MA, 35LAC+USC/Keck Medicine of USC, Pasadena, CA, 36Mayo Clinic, Jacksonville, FL, 37Division of Rheumatology, Mayo Clinic, Rochester, MN, 38Mayo Clinic, Rochester, MN, 39Hospital Guillermo Almenara Irigoyen, Essalud/Universidad Científica del Sur, Lima, Peru, 40McMaster University, Hamilton, ON, Canada, 41Boston University, Boston, MA, 42Boston Children's Hospital / Beth Israel Deaconess Medical Center, Cambridge, MA, 43HealthPartners, Eagan, MN, 44Crystal Run Health, Montvale, NJ, 45University of Otago, Wellington, New Zealand, 46Irish Children's Arthritis Network, Bansha, Ireland, 47University of California San Francisco, Antioch, CA, 48Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, 49Liga Portuguesa Contra as Doenças Reumáticas (LPCDR), Lisbon, Portugal, 50University of Manchester, Manchester, United Kingdom, 51Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France, 52Instituto de Salud Musculoesqueltica (InMusc), Madrid, Spain, 53Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 54German Rheumatism Research Center, Berlin, Germany, 55Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 56University of Queensland School of Clinical Medicine, Brisbane, Queensland, Australia, Herston, Australia

    Background/Purpose: Patients with primary systemic vasculitis (PSV) and polymyalgia rheumatica (PMR) may be at high risk for poor COVID-19 outcomes due to the treatments used,…
  • Abstract Number: 1409 • ACR Convergence 2021

    Clinical Features at Disease Onset of Different Subsets of Large-vessel-giant Cell Arteritis in a Monocentric Cohort of 100 Patients

    Francesca Regola1, Giovanni Bosio2, Laura Andreoli3, Franco Franceschini1 and Paola Toniati1, 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, 2Nuclear Medicine Unit, ASST Spedali Civili of Brescia, Brescia, Italy, 3University of Brescia, Brescia, Italy

    Background/Purpose: Giant Cell Arteritis (GCA) is the most frequent systemic vasculitis in patients older than 50 years involving medium-sized and large arteries. Inflammation of the…
  • Abstract Number: 1194 • ACR Convergence 2021

    A Module on Large Vessel Vasculitis for Learners in Rheumatology

    David Shoemaker1, Stamatina Danielides1, Abhishek Nandan1, Huzaefah Syed2, Beth Rubinstein1 and Seema Patel1, 1Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA

    Background/Purpose: Of the rheumatic disorders that learners are expected to know, the vasculitides are among the hardest to grasp. Their pathogenesis is not well-established, they…
  • Abstract Number: 1410 • ACR Convergence 2021

    Predictors of Relapse in Giant-Cell Arteritis: A Retrospective Single Center Analysis

    Kathleena D'Anna1, David Lim2, Lorena Salto1 and Mehrnaz Hojjati1, 1Loma Linda University Health, Loma Linda, CA, 2Loma Linda University Health, Redlands, CA

    Background/Purpose: Giant Cell Arteritis (GCA) is the most common systemic vasculitis in North America, typically affecting Caucasian female adults over 50 years of age. Flares…
  • Abstract Number: L06 • ACR Convergence 2020

    Mavrilimumab (anti GM-CSF Receptor α Monoclonal Antibody) Reduces Time to Flare and Increases Sustained Remission in a Phase 2 Trial of Patients with Giant Cell Arteritis

    Maria C. Cid1, Sebastian Unizony2, Lara Pupim3, Fang Fang4, Joseph Pirrello3, Ai Ren4, Manoj Samant4, Teresa Zhou4 and John F Paolini4, 1Hospital Clinic Barcelona, Barcelona, Spain, 2Massachusetts General Hospital, Boston, MA, 3Kiniksa Pharmaceuticals, Lexington, MA, 4Kiniksa Pharmaceuticals, Lexington

    Background/Purpose: T helper (Th)1 and Th17 lymphocytes play a role in the pathogenesis of giant cell arteritis (GCA). Current treatments (e.g., corticosteroids and tocilizumab) target…
  • Abstract Number: 0517 • ACR Convergence 2020

    Trends in the Incidence and Use of Diagnostic Modalities for Giant Cell Arteritis over Seven Decades: A Population-based Study

    Thomas Garvey1, Cynthia Crowson2, Matthew J. Koster3 and Kenneth Warrington3, 1Mayo Clinic Rochester, Apple Valley, MN, 2Mayo Clinic, Rochester, Minnesota, USA, Rochester, MN, 3Mayo Clinic, Rochester, MN

    Background/Purpose: Diagnostic methods for giant cell arteritis (GCA) have evolved over recent decades, and large vessel imaging plays an increasing role in disease detection.   The…
  • Abstract Number: 1928 • ACR Convergence 2020

    Quantitative Ultrasound of Temporal, Axillary and Subclavian Arteries to Monitor Tocilizumab Treatment in Patients with Newly Diagnosed Giant Cell Arteritis: A 24 Week Analysis

    Luca Seitz1, Lisa Christ1, Godehard Scholz1, Fabian Lötscher1, Jennifer Amsler1, Florian Kollert1, Stephan Reichenbach1 and Peter Villiger1, 1Department of Rheumatology, Immunology and Allergology, University of Bern, Inselspital, Switzerland, Bern, Switzerland

    Background/Purpose: Tocilizumab (TCZ) suppresses CRP. Thus, CRP cannot be used as a marker for disease activity in GCA patients treated with TCZ and monitoring of…
  • Abstract Number: 1945 • ACR Convergence 2020

    Characterization of Visual Manifestations and Identification of Risk Factors for Permanent Vision Loss in Patients with Giant Cell Arteritis

    Hussein Baalbaki1, Darya Jalaledin2, Catherine Lachance2 and Jean-Paul Makhzoum3, 1Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, 2Universite de Montreal, Montreal, QC, Canada, 3Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada

    Background/Purpose: Permanent vision loss (PVL) is a feared complication and a leading cause of morbidity in Giant Cell Arteritis (GCA). Multiple risk factors for ocular…
  • Abstract Number: 0518 • ACR Convergence 2020

    The Impact of Large Vessel Vasculitis of the Axillary Artery on Cumulative Glucocorticoid Dose and Relapse Rate in Giant Cell Arteritis

    Philipp Bosch1, Christian Dejaco2, Wolfgang Schmidt3, Andreas Krause3, Kenny-Davis Schlüter3, Gudrun Pregartner4 and Valentin Schaefer5, 1Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria, Graz, Austria, 2Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria and Rheumatology Service, Hospital of Bruneck, Bruneck, Italy, Bruneck, Italy, 3Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch, Berlin, Germany, 4Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria, Graz, Austria, 5Clinic of Internal Medicine III, Department of Oncology, Hematology and Rheumatology, University Hospital Bonn, Germany, Bonn, Nordrhein-Westfalen, Germany

    Background/Purpose: Prognostic markers for clinical outcomes in giant cell arteritis (GCA) are urgently needed. While large vessel GCA (LV-GCA) has been associated with higher glucocorticoid…
  • Abstract Number: 1929 • ACR Convergence 2020

    Visual Ischemia During Relapse and Follow-up of Giant Cell Arteritis: A Systematic Review

    Kubra Bugdayli1, Patompong Ungprasert2, Kenneth Warrington3 and Matthew J. Koster3, 1Case Western Reserve University MetroHealth Medical Center, Cleveland, 2Cleveland Clinic Foundation, Cleveland, 3Mayo Clinic, Rochester, MN

    Background/Purpose: The purpose of this study was to characterize the frequency of visual ischemia (VI) as a manifestation of relapse or during follow-up in patients…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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