Abstracts tagged "giant cell arteritis"

Abstract Number: 0766 • ACR Convergence 2023
The OMERACT GCA Phantom Project: Validation of 3D Printed Ultrasound Training Models for Giant Cell Arteritis
Valentin Sebastian Schäfer¹, Tobias Schremmer², Florian Recker³, Wolfgang Hartung⁴, Christina Duftner⁵, Sara Monti⁶, Alojzija Hocevar⁷, Rositsa Karalilova⁸, Annamaria Iagnocco⁹, PIERLUIGI MACCHIONI¹⁰, Giuseppe Antonio Germano¹¹, Maria Esperanza Naredo Sanchez¹², Eugenio De Miguel¹³, Luca Seitz¹⁴, Thomas Daikeler¹⁵, Markus Aschwanden¹⁶, Dennis Boumans¹⁷, Chetan Mukhtyar¹⁸, smith kate¹⁹, Richard Wakefield²⁰, Andreas Diamantopoulos²¹, Stavros Chrysidis²², Berit Dalsgaard Nielsen²³, Kresten Keller²⁴, Uffe Dohn²⁵, Lene Terslev²⁶, Marcin Milchert²⁷, Aaron Juche²⁸, Wolfgang Schmidt²⁹, George A. W. Bruyn³⁰ and Christian Dejaco³¹, ¹Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, ²Universitätsklinikum Bonn, Bonn, Germany, ³Department for Gynecology and Obstetrics, University Hospital Bonn, Bonn, Germany, ⁴Asklepios Clinic, Tegernheim, Germany, ⁵Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University Innsbruck, Innsbruck, Austria, ⁶Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine and Therapeutics, Università di Pavia, Pavia, Italy, ⁷Department of Rheumatology, Universitiy Medical Centre Ljubljana, Ljubljana, Slovenia, ⁸Clinic of Rheumatology, Medical University Plovdiv, Plovdiv, Bulgaria, ⁹University of Turin, Roma, Italy, ¹⁰Azienda USL -IRCCS di Reggio Emilia, Reggio Emilia, Italy, ¹¹Rheumatology Unit- Arcispedale Santa Maria Nuova Reggio Emilia-Italy, Reggio Emilia, Italy, ¹²Rheumatology Department and Joint and Bone Research Unit, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, ¹³Hospital Universitario La Paz, Madrid, Spain, ¹⁴Rheumatology and Immunology, Inselspital University Hospital Bern, Bern, Switzerland, ¹⁵Clinic for Rheumatology, University Hospital Basel, Basel, Switzerland, ¹⁶Department of Angiology, University Hospital Basel, Basel, Switzerland, ¹⁷Rheumatology and Clinical Immunology, Hospital Group Twente, Almelo, Netherlands, ¹⁸Vasculitis service, Rheumatology department, Norfolk and Norwich University Hospital, Norwich, United Kingdom, ¹⁹NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ²⁰s Leeds Insitute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²¹Akershus University Hospital, Lørenskog, Norway, ²²Department of Rheumatology, Southwest Jutland Hospital Esbjerg, Esbjerg, Denmark, ²³Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark; Department of Medicine, The Regional Hospital in Horsens, Horsens, Denmark, ²⁴Department of Rheumatology, Aarhus University Hospital; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, ²⁵Copenhagen University Hospital at Hvidovre, Hvidovre, Denmark, ²⁶Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ²⁷Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, ²⁸Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, ²⁹Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, ³⁰Reumakliniek Lelystad, Loenga, Netherlands, ³¹Azienda Sanitaria Alto Adige, Brunico, Italy
Background/Purpose: Ultrasonography has been validated as a diagnostic tool for giant cell arteritis (GCA). There is a need to develop training resources, because the glucocorticoid…
Abstract Number: 1882 • ACR Convergence 2023
Imaging in Diagnosis, Monitoring and Outcome Prediction of Large Vessel Vasculitis: A Systematic Literature Review Informing the 2023 Update of the EULAR Recommendations
Philipp Bosch¹, Milena Bond², Christian Dejaco³, Cristina Ponte⁴, Sarah Mackie⁵, Louise Falzon⁶, Wolfgang Schmidt⁷ and Sofia Ramiro⁸, ¹Medical University of Graz, Graz, Austria, ²Azienda sanitaria dell'Alto Adige, Merano, Italy, ³Department of Rheumatology, Medical University Graz, Graz, Austria; Department of Rheumatology, Hospital of Bruneck (ASAA-SABES), Teaching Hospital of the Paracelsius Medical University, Brunico, Italy, ⁴Department of Rheumatology, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisbon, Portugal; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ⁶University of Sheffield, Sheffield, United Kingdom, ⁷Immanuel Krankenhaus Berlin, Berlin, Germany, ⁸Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Since the development of the EULAR recommendations for the use of imaging in large vessel vasculitis (LVV) in 2017, new data has emerged in…
Abstract Number: 2400 • ACR Convergence 2023
Applanation Tonometry of the Temporal Arteries in Participants with Suspected Giant Cell Arteritis: A Proof of Concept
Jean-Paul Makhzoum¹, Stephanie Ducharme-Benard², Samer Hussein², Rosalie-Selene Meunier², Carolyn Ross³, Alik Chamlian⁴, Jonathan Ducharme⁵, Leia Chamlian⁴, Alae Dhahbi⁴, Christian Pagnoux⁶ and Remi Goupil⁷, ¹Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Canadian Network for Research on Vasculitides, Montreal, QC, Canada, ²Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ³Vasculitis Clinic, Canadian Network for Research on Vasculitides, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁴Laval University, Montreal, QC, Canada, ⁵University of Sherbrooke, Montreal, QC, Canada, ⁶Mount Sinai Hospital, Toronto, ON, Canada, ⁷Hopital du Sacre-Coeur de Montreal, University of Montreal, Montreal, QC, Canada
Background/Purpose: Applanation tonometry (ATn) is a non-invasive, point-of-care tool used to capture arterial pressure waveforms. It can measure arterial pulse wave velocity (PWV), a marker…
Abstract Number: 2418 • ACR Convergence 2023
Effectiveness of Dose Spacing with Tocilizumab in Giant Cell Arteritis Treatment
Sharon Cowley¹, Colm Kirby², Patricia Harkins³, Richard Conway⁴, Grainne Murphy⁵ and David Kane⁶, ¹Tallaght University Hospital, Dublin, Dublin, Ireland, ²Tallaght University Hospital, Dublin, Ireland, ³St James's Hospital, Dublin, Ireland, ⁴Trinity College Dublin, Dublin, Ireland, ⁵Cork University Hospital, Cork, Ireland, ⁶Tallaght University Hospital & Trinity College Dublin, Dublin, Ireland
Background/Purpose: The only steroid sparing agent approved for treatment of Giant Cell Arteritis (GCA) is the anti-interleukin-6 receptor antagonist tocilizumab. There remains uncertainty regarding treatment…
Abstract Number: 2603 • ACR Convergence 2023
Impact of IL-6 Receptor Small Nucleotide Polymorphism Asp358Ala on T Cell Activity and Clinical Outcomes in Patients with Giant Cell Arteritis
Christopher Redmond¹, Robert Zorc², McKella Sylvester³, Cameron Rankin⁴, Rebecca Kuan⁵, Kristina Wells⁶, Lily Dai⁷, Kaitlin Quinn⁸, Massimo Gadina⁹ and Peter Grayson¹⁰, ¹National Institutes of Health, Hagerstown, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases/National Institutes of Health, Bethesda, MD, ³Colgate University, Bethesda, MD, ⁴NIAMS, NIH, Washington, DC, ⁵NIH, Bethesda, MD, ⁶University of California Davis, Bethesda, MD, ⁷NIH, Germantown, MD, ⁸National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, ⁹National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, ¹⁰National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Chevy Chase, MD
Background/Purpose: Giant cell arteritis (GCA) is a large vessel vasculitis in adults that commonly involves the aorta and branching arteries, resulting in multiple symptoms including…
Abstract Number: 0459 • ACR Convergence 2022
The Use of Intravenous Methylprednisolone in Patients with Giant Cell Arteritis: A Population-Based Study
Hampus Henningson¹, Björn Hammar², Carl Turesson³ and Aladdin Mohammad¹, ¹Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden, ²Ophthalmology, Department of Clinical Sciences, Lund University, Lund, Sweden, ³Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden
Background/Purpose: Giant cell arteritis (GCA) is the most common vasculitis in the age-group 50 years and older. Cranial involvement is common and can lead to…
Abstract Number: 0476 • ACR Convergence 2022
Permanent Vision Loss in Giant Cell Arteritis: Why the Incidence Remains High
Andrea Hemmig¹, Markus Aschwanden², Sabine Seiler¹, Christoph Berger³, Philipp Köhn¹, Noemi Mensch¹, Daniel Staub², Mihaela Stegert¹, Stephan Imfeld² and Thomas Daikeler¹, ¹Department of Rheumatology, University Hospital Basel, Basel, Switzerland, ²Department of Angiology, University Hospital Basel, Basel, Switzerland, ³Departments of Dermatology, Rheumatology and Internal Medicine, University Center for Immunology, University Hospital Basel, Basel, Switzerland
Background/Purpose: Permanent vision loss (PVL) remains the most feared complication of giant cell arteritis (GCA). In recent years, fast track clinic approaches for early GCA…
Abstract Number: 0492 • ACR Convergence 2022
Longitudinal Tends of Hospitalizations for Giant Cell Arteritis: A 21-year Longitudinal National Population-based Study
Ehizogie Edigin¹, Amy Trang², Solomon Anighoro³, Chinenye Osuorji⁴, Precious Eseaton⁵, Osahon Idolor⁶, Christopher Hino¹, Nneka Chukwu⁷ and Mehrnaz Hojjati¹, ¹Loma Linda University Health, Loma Linda, CA, ²Rush University Medical Center, Chicago, IL, ³St. Helens and Knowsley Teaching hospitals NHS Trust, Prescot, England, United Kingdom, ⁴Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY, ⁵University of South Wales, Cardiff, Wales, United Kingdom, ⁶Piedmont Athens Regional, Atlanta, GA, ⁷Nuvance Health, Poughkeepsie
Background/Purpose: Giant Cell Arteritis (GCA) is the most common vasculitis in patients more than 50 years of age in the western countries. Although corticosteroids remain…
Abstract Number: 1618 • ACR Convergence 2022
Combined Orbital and Cranial Vessel Wall MRI for Diagnosis and Longitudinal Monitoring of Giant Cell Arteritis
Rennie Rhee, Shubhasree Banerjee, Vatsal Bhatt, Madhura Tamhankar, Quy Cao, Naomi Amudala, Sherry Chou, Morgan Burke, Laurie Loevner, Peter Merkel and Jae Song, University of Pennsylvania, Philadelphia, PA
Background/Purpose: In giant cell arteritis (GCA), there is a critical need to identify patients at risk for vision loss ("ocular GCA"). MRI evaluates neurovascular anatomy…
Abstract Number: 0460 • ACR Convergence 2022
Baseline Glucocorticoid Toxicity in the Treatment of Giant Cell Arteritis: A Post Hoc Analysis of the GiACTA Trial
Naomi Patel¹, Xiaoqing Fu², yuqing zhang³ and John Stone⁴, ¹Massachusetts General Hospital, Sale Creek, TN, ²Massachusetts General Hospital, Boston, MA, ³Massachusetts General Hospital, Quincy, MA, ⁴Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA
Background/Purpose: Giant cell arteritis (GCA) requires treatment with high-dose, long-term glucocorticoids (GCs). The development of future GC toxicities may be predicted by baseline toxicities. Thus,…
Abstract Number: 0477 • ACR Convergence 2022
Can Beta-blockers Prevent Aortic Dilation in Patients with Giant Cell Arteritis and Large Vessel Vasculitis?
Hubert De Boysson¹, Anael DUMONT², Samuel DESHAYES², Alexandre Nguyen² and Achille Aouba¹, ¹Department of Internal Medicine, UR4650 PSIR, Normandie Univ, UNICAEN, CHU de Caen Normandie, Caen, France, ²Caen University Hospital, Caen, France
Background/Purpose: We analyzed whether the use of beta-blockers in addition to conventional care in patients with Giant cell arteritis (GCA) and large vessel vasculitis (LVV)…
Abstract Number: 0493 • ACR Convergence 2022
MRI Is Superior to Ultrasound of Supraaortic Arteries in Detecting Giant Cell Arteritis – Experience of a Single Center
Matthias Froehlich¹, Thorsten A. Bley², Marc Schmalzing³, Michael Gernert¹, Rudolf A. Werner⁴, Jost Hillenkamp⁵, Karl Georg Haeusler⁶ and Konstanze V. Guggenberger², ¹University Hospital Wuerzburg, Dpt. of Internal Medicine II, Wuerzburg, Germany, ²University Hospital Wuerzburg, Dpt. of Radiology, Wuerzburg, Germany, ³University Hospital Wuerzburg, Wuerzburg, Germany, ⁴University Hospital Wuerzburg, Dpt. of Nuclear medicine, Wuerzburg, Germany, ⁵University Hospital Wuerzburg, Dpt. of Ophtalmology, Wuerzburg, Germany, ⁶University Hospital Wuerzburg, Dpt. of Neurology, Wuerzburg, Germany
Background/Purpose: Imaging techniques for the detection of mural inflammation are cornerstones in the diagnosis of giant cell arteritis (GCA). Magnetic resonance imaging (MRI) and ultrasound…
Abstract Number: 1619 • ACR Convergence 2022
Silent Giant Cell Arteritis in Patients with Polymyalgia Rheumatica: Characteristics and Peculiarities
Eugenio De Miguel¹, PIERLUIGI MACCHIONI², Edoardo Conticini³, Corrado Campochiaro⁴, Rositsa Karalilova⁵, Sara Monti⁶, Cristina Ponte⁷, Giulia Klinowski², Irene Monjo⁸, Paolo Paolo Falsetti³, Anastas Batalov⁹, alessandro tomelleri⁴ and Alojzija Hocevar¹⁰, ¹Hospital Universitario La Paz, Madrid, Spain, ²IRCCS-S.Maria Nuova, Reggio Emilia, Italy, ³Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy, ⁴IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University, Milano, Italy, ⁵Medical University of Plovdiv, University Hospital Kaspela, Plovdiv, Bulgaria, ⁶Rheumatology, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy, ⁷Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte EPE, Lisboa, Portugal, ⁸Hospital Universitario La Paz - IdiPAZ, Madrid, Spain, ⁹Medical University of Plovdiv, Plovdiv, Bulgaria, ¹⁰University Medical Centre Ljubljana, Ljubljana, Slovenia
Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are closely related diseases. PMR occurs in approximately 50 % of patients with GCA. In a…
Abstract Number: 0461 • ACR Convergence 2022
The Effects of Daily Prednisone and Tocilizumab on Hemoglobin A1c During the Treatment of Giant Cell Arteritis
Naomi Patel¹, Veronica Tozzo², John Higgins² and John Stone³, ¹Massachusetts General Hospital, Sale Creek, TN, ²Massachusetts General Hospital, Boston, MA, ³Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA
Background/Purpose: Hemoglobin A1c (HbA1c) is used clinically to estimate patients' average blood glucose over the preceding few months and is affected by glycemic as well…
Abstract Number: 0478 • ACR Convergence 2022
Sonographic Prevalence of Subclinical GCA in Newly Diagnosed PMR
Colm Kirby¹, Rachael Flood¹, Ronan Mullan¹, Grainne Murphy² and David Kane¹, ¹Tallaght University Hospital, Dublin, Ireland, ²Cork University Hospital, Cork, Ireland
Background/Purpose: It has been reported that 20-50% of patients with PMR have subclinical GCA. The natural history of US-defined subclinical GCA in PMR is not…

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