Abstracts tagged "giant cell arteritis"

Abstract Number: 1395 • ACR Convergence 2021
Utility and Validity of the Southend Pretest Probability Score (SPTPS) in a Giant Cell Arteritis Fast Track Clinic: Analysis in a Spanish Cohort of 297 Patients
Elisa Fernández-Fernández¹, Irene Monjo² and Eugenio De Miguel³, ¹Rheumatology department, La Paz University Hospital, Madrid, Spain, ²Hospital La Paz - IdiPAZ, Madrid, Spain, ³Hospital Universitario La Paz, Madrid, Spain
Background/Purpose: The implementation of fast track clinics (FTC) has enabled quick diagnosis and reduced the blindness rate of giant cell arteritis (GCA). Recently, the Southend…
Abstract Number: 1412 • ACR Convergence 2021
Effectiveness of Tocilizumab in the Visual Involvement of Giant Cell Arteritis: Multicenter Study of 471 Patients of Clinical Practice
Lara Sánchez-Bilbao¹, Javier Loricera¹, Juan Pablo Valdivieso Achá², Clara Moriano³, Javier Narvaez⁴, Vicente Aldasoro⁵, Olga Maíz⁶, Rafael Melero⁷, Juan Ignacio Villa⁸, Paloma Vela⁹, Susana Romero-Yuste¹⁰, José Luis Callejas¹¹, Eugenio De Miguel¹², Eva Galindez-Agirregoikoa¹³, Francisca Sivera¹⁴, Jesús Carlos Fernández-López¹⁵, Carles Galisteo¹⁶, Iván Ferraz-Amaro¹⁷, Juan Carlos Nieto¹⁸, Juan Ramón de Dios¹⁹, Julio Sánchez²⁰, Esther Fernández²¹, Isabel de la Morena²², Patricia Moya²³, Roser Solans-Laqué²⁴, Jose Luis Andreu²⁵, Marcelino Revenga²⁶, Valvanera Pinillos²⁷, Andrea García-Valle²⁸, Adela Gallego²⁹, Carlota Iñíguez³⁰, Cristina Hidalgo³¹, Noemí Garrido-Puñal³², Ruth López-González³³, José Andrés Román-Ivorra³⁴, Sara Manrique Arija³⁵, Paz Collado³⁶, Enrique Raya¹¹, Francisco Navarro³⁷, Antoni Juan Mas³⁸, Carmen Ordas³⁹, Maria Dolors Boquet⁴⁰, Noelia Álvarez-Rivas⁴¹, Maria Luisa Velloso-Feijoo⁴², Cristina Campos-Fernández⁴³, Íñigo Rúa-Figueroa⁴⁴, Arantxa Conesa⁴⁵, Eva Salgado⁴⁶, Miguel Ángel gonzalez-Gay⁴⁷ and Ricardo Blanco⁴⁸, ¹Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Hospital Universitario La Princesa, Madrid, Spain, ³Hospital Universitario de León, León, Spain, ⁴Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁵Complejo Hospitalario de Navarra, Pamplona, Spain, ⁶Hospital Universitario de Donostia, San Sebastián, Spain, ⁷Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, ⁸Hospital Sierrallana, Torrelavega, Spain, ⁹Hospital General Universitario de Alicante, Alicante, Spain, ¹⁰Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain, ¹¹Hospital San Cecilio, Granada, Spain, ¹²Hospital Universitario La Paz, Madrid, Spain, ¹³Hospital Universitario de Basurto, Bilbao, Spain, ¹⁴Hospital Universitario de Elda, Alicante, Spain, ¹⁵Hospital Universitario Juan Canalejo, A Coruña, Spain, ¹⁶Hospital Universitari Parc Tauli, Saadell, Spain, ¹⁷Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ¹⁸Hospital General Universitario Gregorio Marañón, Madrid, Spain, ¹⁹Hospital Universitario de Araba, Mondragón, Spain, ²⁰Hospital Universitario 12 de Octubre, Madrid, Spain, ²¹Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain, ²²Hospital Clínico Universitario de Valencia, Valencia, Spain, ²³Hospital Sant Pau, Barcelona, Spain, ²⁴Hospital Vall d'Hebron, Barcelona, Spain, ²⁵Hospital Universitario Puerta de Hierro, Madrid, Spain, ²⁶Hospital Ramón y Cajal, Madrid. Spain., Madrid, Spain, ²⁷Hospital San Pedro, Logroño, Spain, ²⁸Complejo Asistencial Universitario de Palencia, Palencia. Spain, Palencia, Spain, ²⁹Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, ³⁰Hospital Universitario Lucus Augusti, Lugo, Galicia, Spain, ³¹Hospital Universitario Salamanca, Salamanca, Spain, ³²Hospital Universitario Virgen del Rocío, Sevilla, Spain, ³³Complejo Hospitalario de Zamora, Zamora, Spain, ³⁴Hospital Universitario y Politécnico La Fe, Valencia, Spain, ³⁵Hospital Regional de Málaga, Málaga. Spain., Malaga, Spain, ³⁶Hospital Universitario Severo Ochoa, Madrid, Spain, ³⁷Hospital General Universitario de Elche, Elche, Spain, ³⁸Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, ³⁹Hospital de Cabueñes, Gijón, Spain, ⁴⁰Hospital Arnau de Vilanova, Lleida. Spain., Lleida, Spain, ⁴¹Hospital San Agustín, Aviles, Spain, ⁴²Hospital Universitario de Valme, Sevilla, Spain, ⁴³Consorci Hospital General Universitari de Valencia, Valencia, Spain, ⁴⁴Hospital Universitario Doctor Negrín, Gran Canaria, Spain, ⁴⁵Hospital Universitario de Castellón, Castellón, Spain, ⁴⁶Complejo Hospitalario Universitario de Ourense, Ourense, Spain, ⁴⁷Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, ⁴⁸Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain
Background/Purpose: One of the most feared complications of giant cell arteritis (GCA) is visual affection. Tocilizumab (TCZ) has demonstrated efficacy and safety in GCA. However,…
Abstract Number: 1396 • ACR Convergence 2021
Baricitinib in Relapsing Giant Cell Arteritis: A Prospective Open-Label Single-Institution Study
Matthew Koster¹, Cynthia Crowson², Rachel Giblon¹, Ali Duarte-Garcia¹, Jane Jaquith¹, Cornelia M. Weyand¹ and Kenneth Warrington³, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN, ³Mayo Clinic, Rochester, Minnesota
Background/Purpose: Pre-clinical giant cell arteritis (GCA) mouse models have demonstrated effective suppression of arterial wall lesional T-cells through inhibition of Janus kinase 3 (JAK3) and…
Abstract Number: 1413 • ACR Convergence 2021
Tocilizumab in Combination with 8 Weeks of Prednisone for Giant Cell Arteritis
Mark Matza¹, Adam Jarvie², Ana Fernandes¹, John Stone³ and Sebastian Unizony⁴, ¹Massachusetts General Hospital, Boston, MA, ²Masssachusetts General Hospital, Boston, MA, ³Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ⁴Massachusetts General Hospital, Winchester, MA
Background/Purpose: Even with the use of tocilizumab (TCZ), significant glucocorticoid exposure (usually ³ 6 months) continues to be an important problem in giant cell arteritis…
Abstract Number: 1397 • ACR Convergence 2021
Treatment of Giant Cell Arteritis with Tocilizumab: A Retrospective Cohort Study of 119 Patients
jigisha rakholiya¹, Matthew Koster¹, Hannah Langenfeld¹, Cynthia Crowson², Andy Abril³, Pankaj Bansal⁴, Lester Mertz⁵, Alicia Rodriguez Pla⁶, Rahul Sehgal⁴, Benjamin Wang⁷ and Kenneth Warrington⁸, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN, ³Mayo Clinic, Ponte Vedra Beach, FL, ⁴Mayo Clinic, Eau Claire, WI, ⁵Mayo Clinic Arizona, Scottsdale, AZ, ⁶Mayo Clinic in Arizona, Scottsdale, AZ, ⁷Mayo Clinic, Jacksonville, FL, ⁸Mayo Clinic, Rochester, Minnesota
Background/Purpose: Giant cell arteritis (GCA) is an inflammatory condition of medium- and large-sized arteries. Prospective clinical trials have demonstrated the efficacy of tocilizumab (TCZ) for…
Abstract Number: 1414 • ACR Convergence 2021
The Current State of Expedited Referral Systems Incorporating Vasculitis Ultrasound for the Diagnosis of Giant Cell Arteritis in Rheumatology Practices in the United States
Mark Matza¹, Karina Torralba² and Minna Kohler³, ¹Massachusetts General Hospital, Boston, MA, ²Division of Rheumatology, Department of Medicine, Loma Linda University Healthcare, Loma Linda, CA, ³Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Expedited referral systems or “fast-track” clinics incorporating vasculitis ultrasound (VUS) into the evaluation of patients with suspected giant cell arteritis (GCA) have shown reduced…
Abstract Number: 1398 • ACR Convergence 2021
Adrenal Insufficiency After Glucocorticoid Treatment of Giant Cell Arteritis
Alojzija Hocevar¹, Rok Jese¹, Jelka Kramaric², Matija Tomšič³ and Ziga Rotar³, ¹UKC Ljubjana, Ljubjana, Slovenia, ²UKC Ljubjana, Ljubjana, ³Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia
Background/Purpose: Adrenal insufficiency is frequently neglected and underappreciated complication of systemic glucocorticoid therapy. We aimed to evaluate the prevalence of glucocorticoid induced adrenal insufficiency in…
Abstract Number: 1415 • ACR Convergence 2021
Temporal Artery Biopsy Reports Can Be Accurately Classified by Artificial Intelligence
Christopher McMaster¹, Victor Yang¹, Benjamin Sutu², Shereen Oon³, Gene-Siew Ngian³, Ian Wicks³, Russell Buchanan⁴ and David Liew¹, ¹Austin Health, Heidelberg, Australia, ²Melbourne Health, South Yarra, Australia, ³Melbourne Health, Parkville, Australia, ⁴Austin Health, Heidelberg, Melbourne, Australia
Background/Purpose: Studies of giant cell arteritis (GCA) rely on classifying temporal artery biopsies (TABs), the gold-standard diagnostic test. However, these results exist as free text,…
Abstract Number: 0151 • ACR Convergence 2021
Usefulness of Ultrasound and (FDG) PET/CT to Detect Cranial and Extracranial Artery Involvement in Patients with Suspected Large Vessel Vasculitis
Juan Molina¹, Isabel Castrejón², Javier Rivera², Julia Martínez Barrio², Juan Carlos Nieto², Katerine López², Fernando Montero², Laura Trives Folguera², Carlos González³ and Jose Maria Alvaro-Gracia², ¹Hospital General Universitario Gregorio Maran, Madrid, Spain, ²Hospital General Universitario Gregorio Marañón, Madrid, Spain, ³CEIMI, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Background/Purpose: Ultrasound (US) is recommended as the first imaging modality to assess patients presenting with predominantly cranial symptoms of giant cell arteritis (GCA). However, its…
Abstract Number: 1399 • ACR Convergence 2021
Validation of a Giant Cell Arteritis Probability Score
Charlie Oshinsky¹, Alison Bays¹, Ingeborg Sacksen², Elizabeth Jernberg³, Eugene zierler¹, Andreas Diamantopoulos⁴ and Scott Pollock¹, ¹University of Washington, Seattle, WA, ²University of Washington, Bellingham, WA, ³Virginia Mason Medical Center, Seattle, WA, ⁴Akerhus University Hospital, Brum, Norway
Background/Purpose: Giant cell arteritis (GCA) is the most common large vessel vasculitis. Failure to rapidly diagnose and treat patients with GCA can result in irreversible…
Abstract Number: 1416 • ACR Convergence 2021
Dysregulated Glucose Metabolism and Dyslipidemia in GCA and PMR Patients at Diagnosis
Idil Esen¹, Philip Therkildsen², Berit Dalsgaard Nielsen², Anna van 't Ende¹, Annemieke Boots¹, Peter Heeringa¹, Ellen-Margrethe Hauge², Elisabeth Brouwer¹ and Yannick van Sleen³, ¹University Medical Center Groningen, Groningen, Netherlands, ²Aarhus University Hospital, Aarhus, Denmark, ³University of Groningen, Groningen, Netherlands
Background/Purpose: Giant cell arteritis (GCA) is the large and medium vasculitis that affects elderly people GCA frequently overlaps with polymyalgia rheumatica (PMR). PMR is a…
Abstract Number: 0163 • ACR Convergence 2021
Diagnosis of Giant Cell Arteritis in Spain: Data from the ARTESER Registry
Eugenio De Miguel¹, Jesús T. Sánchez-Costa², Javier Narvaez³, Miguel Ángel gonzalez-Gay⁴, Noemí Garrido-Puñal⁵, Paula V. Estrada-Alarcon⁶, Iñigo Hernández-Rodríguez⁷, Elisa Fernández-Fernández⁸, María T. Silva-Diaz⁹, Jesús A. Valero-Jaimes¹⁰, Ismael González-Fernández¹¹, Julio Sánchez¹², Judit Lluch¹³, Eva Galindez-Agirregoikoa¹⁴, Javier Mendizábal-Mateos¹⁵, Luis Rodriguez Rodriguez¹⁶, Javier Loricera García¹⁷, Alejandro Muñoz¹⁸, Santos Castañeda¹⁹, Patricia Moya²⁰, Patricia Morán-Álvarez²¹, Vanessa A. Navarro-Angeles⁶, Joan Calvet-Fontova²², Ivette Casafont²³, Francisco Ortiz-Sanjuán²⁴, Selene Labrada-Arrabal²⁵, Cristina Campos-Fernández²⁶, María Alcalde-Villar²⁷, Antonio Juan-Mas²⁸ and Ricardo Blanco²⁹, ¹Hospital Universitario La Paz, Madrid, Spain, ²Spanish Society of Rheumatology, Madrid, Spain, ³Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, ⁵Hospital Universitario Virgen del Rocío, Sevilla, Spain, ⁶Hospital de Sant Joan Despí Moisès Broggi. Sant Joan Despí, Barcelona, Spain, ⁷Complejo Hospitalario Universitario de Vigo, Vigo, Spain, ⁸Rheumatology department, La Paz University Hospital, Madrid, Spain, ⁹Complejo Hospitalario Universitario de La Coruña, Coruña, Spain, ¹⁰Hospital Universitario Donostia, Donostia-San Sebasti, Spain, ¹¹Hospital Universitario de León, León, Spain, ¹²Hospital Universitario 12 de Octubre, Madrid, Spain, ¹³Hospital Universitari Bellvitge, Hospitalet de Llobregat, Spain, ¹⁴Hospital Universitario de Basurto, Bilbao, Spain, ¹⁵H. Navarra, Navarra, Spain, ¹⁶Hospital Clinico San Carlos, Madrid, Spain, ¹⁷Hospital Universitario Marqués de Valdecilla, Santander, Spain, ¹⁸Hospital Universitario Virgen del Rocío, Sevial, Spain, ¹⁹Hospital Universitario de la Princesa, Madrid, Spain, ²⁰Hospital Sant Pau, Barcelona, Spain, ²¹Hospital Universitario Ramón y Cajal, Madrid, Spain, ²²Hospital Universitari Parc Tauli, Sabadell, Spain, ²³Hospital Universitari Germans Trias i Pujol, Barcelona, Badalona, Spain, ²⁴H. La Fe, Valencia, Spain, ²⁵Hospital del Mar, Barcelona, Spain, ²⁶Consorci Hospital General Universitari de Valencia, Valencia, Spain, ²⁷Hospital Universitario Severo Ochoa, Leganés, Spain, ²⁸Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, ²⁹Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain
Background/Purpose: To standardize research studies different classification systems are used. Currently, the ACR Giant Cell Arteritis (GCA) 19901 classification criteria is probably the most widely…
Abstract Number: 1400 • ACR Convergence 2021
Analyses of Plasma Inflammatory Proteins Reveal Biomarkers Predictive of Subsequent Development of Giant Cell Arteritis; A Nested Case-Control Study
Karin Wadström¹, Jan-Åke Nilsson¹, Aladdin Mohammad², Kenneth Warrington³, Eric Matteson⁴, Magnus Jakobsson², Lennart Jacobsson⁵ and Carl Turesson⁶, ¹Lund University, Malmö, Sweden, ²Lund University, Lund, Sweden, ³Mayo Clinic, Rochester, MN, ⁴Mayo Clinic College of Medicine and Science, Rochester, MN, ⁵University of Gothenburg, Gothenburg, Sweden, ⁶Lund University, Malm, Sweden
Background/Purpose: Previous studies have demonstrated that metabolic factors may predispose to giant cell arteritis (GCA). The purpose of this study was to investigate the relation…
Abstract Number: 1417 • ACR Convergence 2021
Machine Learning Enhances the Identification of GCA from Its Mimics Based on Clinical Factors
Christopher McMaster¹, Victor Yang¹, Russell Buchanan² and David Liew¹, ¹Austin Health, Heidelberg, Australia, ²Austin Health, Heidelberg, Melbourne, Australia
Background/Purpose: To determine whether an eventual diagnosis of giant cell arteritis in both temporal artery biopsy positive and negative patients can be identified using prospective…
Abstract Number: 0466 • ACR Convergence 2021
Subclinical Large Vessel Vasculitis in Polymyalgia Rheumatica
Eugenio De Miguel¹, Pierluigi Macchioni², Edoardo Conticini³, Corrado Campochiaro⁴, Rositsa Karalilova⁵, Giulia Klinowski², Paolo Falsetti³, Irene Monjo⁶, Alessandro Tomelleri⁷, Zguro Batalov⁵ and Alojzija Hocevar⁸, ¹Hospital Universitario La Paz, Madrid, Spain, ²Department of Rheumatology, IRCCS-S.Maria Nuova, Reggio Emilia, Italy, ³Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy, ⁴Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR). San Raffaele Scientific Institute, Milan. Italy, Milan, Italy, ⁵Medical University of Plovdiv, University Hospital Kaspela, Plovdiv, Bulgaria, ⁶Hospital La Paz - IdiPAZ, Madrid, Spain, ⁷Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR). San Raffaele Scientific Institute, Milan, Milan, Italy, ⁸UKC Ljubjana, Ljubjana, Slovenia
Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are closely related diseases. PMR occurs in approximately 50 % of GCA patients1, however the frequency…

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