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Abstracts tagged "Fracture risk"

  • Abstract Number: 1181 • 2016 ACR/ARHP Annual Meeting

    Risk Factors for Incident Fractures in Patients with Systemic Lupus Erythematosus on Dialysis

    Brian Le1,2, Jennifer Waller3, Reshmitha Radhakrishnan4, Sun Jung Oh4, Monique Bethel2,5, Christopher Rice4 and Laura Carbone2,6, 1Department of Internal Medicine, Augusta University, Augusta, GA, 2Specialty Care, Charlie Norwood VA Medical Center, Augusta, GA, 3Biostatistics, Augusta University, Augusta, GA, 4School of Medicine, Augusta University, Augusta, GA, 51120 15th Street, BI 5070, Augusta University, Augusta, GA, 6Rheumatology, Augusta University, Augusta, GA

    Background/Purpose:  Osteoporosis and osteoporotic fractures are significant comorbidities in patients with systemic lupus erythematosus (SLE). Hip fractures are being increasingly recognized as a complication of…
  • Abstract Number: 1232 • 2016 ACR/ARHP Annual Meeting

    Interdisciplinary Osteoporosis Clinical Working Group and Fracture Liaison Service at Loma Linda University Medical Center (LLUMC): Laying the Groundwork

    Karina Marianne D. Torralba1, Micah Yu2, Cong-Bin Wang3, Kevin A. Codorniz4, James P. Larsen3, Silvana M Giannelli5, Vaneet Sandhu6, Nasim Daoud7 and Gary D. Botimer3, 1Rheumatology, Loma Linda University, Loma Linda, CA, 2Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, 3Loma Linda University Medical Center, Loma Linda, CA, 4Loma Linda University University Medical Center, Loma Linda, CA, 5Division of Endocrinology, Loma Linda University, Loma Linda, CA, 6Division of Rheumatology, Loma Linda University, Loma Linda, CA, 7Division of Rheumatology, Loma Linda University Medical Center, Loma Linda, CA

    Background/Purpose:  There is an ongoing effort worldwide to effect quality improvement to address secondary prevention of fractures. Patients who have incurred fractures attributed to osteoporosis…
  • Abstract Number: 1705 • 2016 ACR/ARHP Annual Meeting

    The Risk of Fracture Among Patients with Psoriasis, Psoriatic Arthritis and Rheumatoid Arthritis

    Lauren Harter1, Daniel Shin2, Joshua F. Baker3, Junko Takeshita2, Thorvardur Love4,5, Joel Gelfand6 and Alexis Ogdie7, 1Medicine, University of Pittsburgh, Pittsburgh, PA, 2University of Pennsylvania, Philadelphia, PA, 3Rheumatology, University of Pennsylvania, Philadelphia, PA, 4Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 5Landspitali University Hospital, Reykjavík, Iceland, 6University of Pennsylvania Health System , Philadelphia, PA, 7Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: While rheumatoid arthritis (RA) has been linked to an increased incidence of osteoporosis (OP) and fracture, few studies have examined the risk of fracture…
  • Abstract Number: 2541 • 2016 ACR/ARHP Annual Meeting

    Glucocorticoid Use and Low Thoracic Bone Mineral Density Are Predictors for Clinical Fractures in Patients with Rheumatoid Arthritis: Five-Year Findings of the Tomorrow Study

    Kenji Mamoto1, Kentaro Inui2, Tadashi Okano1, Yuko Sugioka3, Masahiro Tada4, Tatsuya Koike5 and Hiroaki Nakamura6, 1Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Rheumatology & Orthopaedics, Higashisumiyoshi Morimoto Hospital, Osaka, Japan, 3o, Osaka, Japan, 4Orthopedic Surgery, Osaka City General Hospital, Osaka, Japan, 5Center for Senile Degenerative Disorders (CSDD), Osaka City University Graduate School of Medicine, Osaka, Japan, 6Orthopaedic Surgery, Osaka City University Medical School, Osaka, Japan

    Background/Purpose: Patients with rheumatoid arthritis (RA) who have muscle weakness and stiff or painful joints might be at increased risk of falls and fractures. The…
  • Abstract Number: 364 • 2015 ACR/ARHP Annual Meeting

    Very High Frequency of Fragility Fractures Associated with High-Dose Glucocorticoids in Postmenopausal Women: A Retrospective Study

    Goichi Kageyama1, Takaichi Okano1, Yuzuru Yamamoto1, Keisuke Nishimura1, Daisuke Sugiyama2, Jun Saegusa1, Goh Tsuji3, Shunichi Kumagai4 and Akio Morinobu1, 1Department of Rheumatology, Kobe University Hospital, Kobe, Japan, 2Department of Preventive Medicine and Public Health, Keio University, Tokyo, Japan, 3The Center for Rheumatic Diseases, Shinko Hospital, Kobe, Japan, 4The Center of Rheumatic Diseases, Shinko Hospital, Kobe, Japan

    Background/Purpose: To evaluate the incidence of fragility fractures associated with high-dose glucocorticoid therapy in patients with systemic rheumatic disease.Methods: A retrospective study of patients who were treated with high-dose…
  • Abstract Number: 369 • 2015 ACR/ARHP Annual Meeting

    Incidence of Fragility Hip Fractures over 10 Years (2004-13) in Three UK Centres with Reference to Local Fracture Prevention (‘fracture liaison’) Service Activity

    Gavin Clunie1 and Jonathan Belsey2, 1Rheumatology, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom, 2JB Medical, Sudbury, United Kingdom

    Background/Purpose: Fracture Liaison Services systematically identify patients with fragility fracture and screen patients for osteoporosis and associated conditions and instigate evidence-based 'secondary' fracture prevention management.…
  • Abstract Number: 373 • 2015 ACR/ARHP Annual Meeting

    Compared to Non-Users, Current Glucocorticoids Users Have Less Prevalent Fractures at the Same Bone Mass: Results of a Large Cross-Sectional Study

    Marwan Bukhari1, Nicola Goodson2,3 and Maarten Boers4, 1Rheumatology, Royal Lancaster Infirmary, Consultant and Honorary Senior Lecturer, Lancaster, United Kingdom, 2Rheumatology, University of Liverpool, Liverpool, United Kingdom, 3Rheumatology, University Hospital Aintree, Liverpool, United Kingdom, 4Amsterdam Rheumatology and Immunology Center, VU University Medical center, Amsterdam, Netherlands

    Background/Purpose: It is widely believed that use of glucocorticoids (GC) increase risk of fracture through reduction in bone quality as well as reduction in bone…
  • Abstract Number: 378 • 2015 ACR/ARHP Annual Meeting

    Osteoporotic Fragility Tibia/Fibula Fractures Are Not Asociated with a Low Body Mass Index: An Observational Study

    Vishnu Kammath1 and Marwan Bukhari2, 1Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom, 2Rheumatology, Royal Lancaster Infirmary, Consultant and Honorary Senior Lecturer, Lancaster, United Kingdom

    Background/Purpose: Tibia/Fibula (Tib/Fib) fractures are one of osteoporotic fragility fractures. They have been suggested to be more likely to occur secondary to osteoporosis (OP) than…
  • Abstract Number: 2233 • 2015 ACR/ARHP Annual Meeting

    Predictors of Imminent Fracture Risk in Women Aged >=65 Years with Osteoporosis

    Derek Weycker1, Richard Barron2, Alex Kartashov1, John Edelsberg1, DB Crittenden3 and A Grauer3, 1Policy Analysis Inc. (PAI), Brookline, MA, 2Amgen, Inc., Thousand Oaks, CA, 3Amgen Inc., Thousand Oaks, CA

    Background/Purpose: Fractures are the major source of morbidity among women with osteoporosis. However, evidence on factors leading to imminent risk for hip or other non-vertebral…
  • Abstract Number: 228 • 2015 ACR/ARHP Annual Meeting

    Gout and Risk of Non-Vertebral Osteoporotic Fracture

    Seoyoung C. Kim1, Julie M. Paik2, Jun Liu3, Gary C. Curhan2 and Daniel H. Solomon4, 1Div. of Pharmacoepidemiology and Pharmacoeconomics, Div. of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Renal Division, Brigham and Women's Hospital, Boston, MA, 3Division of Pharmaoepidemiology, Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Prior studies suggest an association between osteoporosis, systemic inflammation and pro-inflammatory cytokines such as IL-1 and IL-6. Gout is a common inflammatory arthritis characterized…
  • Abstract Number: 353 • 2015 ACR/ARHP Annual Meeting

    A Longitudinal Cohort Study of Weekly Teriparatide, Denosmab, and Bisphosphonates for Prevention of Vertebral Fractures in Glucocorticoid-Induced Osteoporosis

    Hisaji Oshima1, Mari Ushikubo1, Kumiko Akiya1, Ikuko Tanaka2, Shigenori Tamaki2 and Keisuke Izumi3, 1Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, 2NAGOYA Rheumatology Clinic, Nagoya, Japan, 3National Tokyo Medical Center, Tokyo, Japan

    Background/Purpose: Although weekly teriparatide (56.5ug, wTPTD) and denosmab (DMAB) have been developed as potent anti-osteoporotic agents, effects of these agents on prevention of osteoporotic fractures…
  • Abstract Number: 2047 • 2014 ACR/ARHP Annual Meeting

    No Association of Serum Uric Acid with Hip Fracture Risk in Older Men and Women from the Framingham Original Cohort

    Shivani Sahni1, Kelsey Mangano2, Katherine Tucker3, Caroline Fox4, Douglas P. Kiel5, Xiaochun Zhang6 and Marian T. Hannan1, 1Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2Musculoskeletal Research, Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 3Clinical Laboratory & Nutritional Sciences, Center for Population Health & Health Disparities, University of Massachusetts, Lowell, MA, 4Institute of Genetics and Biophysics, NHLBI's Framingham Heart Study and Center for Population Studies, Framingham, MA, 5Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 6Musculoskeletal Research, Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA

    Background/Purpose:   Serum uric acid (UA) has been linked with fractures in older men. Three different studies in older men showed conflicting results. The objective…
  • Abstract Number: 2004 • 2014 ACR/ARHP Annual Meeting

    Osteoporosis Screening and Fracture Risk Assessment Tool Usage Among House Staff

    Jordan Brodsky1, Meghan Greenfield2 and Erin Patton3, 1Medicine, Albert Einstein College of Medicine, Woodmere, NY, 2279 E 10th St, Beth Israel Medical Center, New York, NY, 3Rheumatology, Beth Israel Medical Center, New York, NY

    Background/Purpose: Despite increased awareness of the magnitude and consequences of osteoporosis and the availability of recommendations for screening and treatment by multiple organizations, osteoporosis is…
  • Abstract Number: 919 • 2014 ACR/ARHP Annual Meeting

    Glucocorticoid Exposure and Fracture Risk in a Large Cohort of Commercially-Insured Rheumatoid Arthritis Patients Under Age 65

    Akhila Balasubramanian1, Sally Wade2, Robert A Adler3, Celia Fang (Lin)4, Michael Maricic5, Cynthia O'Malley1, Kenneth G. Saag6 and Jeffrey R. Curtis7, 1Center for Observational Research, Amgen, Inc., Thousand Oaks, CA, 2Wade Outcomes Research and Consulting, Salt Lake City, UT, 3Internal Medicine, Hunter Holmes McGuire VA Medical Center, Richmond, VA, 4Amgen, Thousand Oaks, CA, 5Catalina Pointe Rheumatology, Tucson, AZ, 6Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, 7The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose Systemic glucocorticoid use can increase fracture risk, although dose-specific effects are not well understood, especially in younger adults.  Underlying diseases (e.g., rheumatoid arthritis [RA])…
  • Abstract Number: 239 • 2014 ACR/ARHP Annual Meeting

    Does Adjusting BMI for Lean Mass Deficits Affect Calculated Fracture Risk Using FRAX in Rheumatoid Arthritis?

    Brittany Adler1 and Joshua F. Baker2, 1Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA

    Background/Purpose Osteoporotic fractures are a cause of morbidity in rheumatoid arthritis (RA) and low body mass index (BMI) is a risk factor for osteoporotic fractures…
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