Abstracts tagged "Fracture risk"

Abstract Number: 338 • 2016 ACR/ARHP Annual Meeting
Abaloparatide-SC Significantly Reduces Vertebral and Nonvertebral Fractures and Increases Bone Mineral Density (BMD) Regardless of Age, BMD T-Score, or Prior Fracture at Baseline
F Cosman¹, Gary Hattersley², PD Miller³, Ming-Yu Hu⁴, Luis Augusto Tavares Russo⁵, Bente Riis⁶, Greg Williams⁷ and Lorraine Fitzpatrick⁸, ¹Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, ²Research, Radius Health, Inc., Waltham, MA, ³Colorado Center for Bone Research, Lakewood, CO, ⁴Biometrics, Radius Health, Inc., Waltham, MA, ⁵CCBR Brasil, Rua Mena Barreto, 33 Botofogo, 22271, Rio de Janeiro, Brazil, ⁶Nordic Biosciences A/S, 2730 Herlev, Denmark, ⁷Clinical Development, Radius Health, Inc., Waltham, MA, ⁸Chief Medical Officer, Radius Health, Inc., Waltham, MA
Background/Purpose: Abaloparatide is a novel 34 amino acid peptide created to be a potent and selective activator of the PTH 1 receptor signaling pathway and…
Abstract Number: 344 • 2016 ACR/ARHP Annual Meeting
Is Rheumatoid Arthritis a Risk Factor for Fractures: A Systematic Review of Observational Studies
Ambika Gupta¹, Stephanie Pipe², Tanveer Towheed³ and Tassos Anastassiades², ¹Internal Medicine, Queen's University, Kingston, ON, Canada, ²Queen's University, Kingston, ON, Canada, ³Dept of Medicine, Queen's University, Kingston, ON, Canada
Background/Purpose: Rheumatoid Arthritis (RA) is a known risk factor for osteoporosis. There are many factors that contribute to this increased risk, including the use of…
Abstract Number: 355 • 2016 ACR/ARHP Annual Meeting
Fracture Incidence Rates in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis
Raveendhara R. Bannuru¹, Elizaveta Vaysbrot², Mikala Osani², Lenore Buckley³, Howard Fink⁴ and Timothy E. McAlindon⁵, ¹Rheumatology, Tufts Med Ctr, Boston, MA, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Rheumatology, Yale University, North Haven, CT, ⁴Minneapolis VA Health Care System, Washington, DC, ⁵Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Transplants increase risk of bone loss and fractures and reduce quality of life. Information on fracture incidence is important when making clinical decisions about…
Abstract Number: 356 • 2016 ACR/ARHP Annual Meeting
Osteoporotic Fracture As the Main Risk Factor in the Detection of Osteoporosis in Men Under 70 Years
JUAN MARIA BLANCO MADRIGAL^1,2, MARIA LUZ GARCIA VIVAR³, Eva Galindez-Agirregoikoa³, OLAIA BEGOÑA FERNANDEZ BERRIZBEITIA⁴, Itziar Calvo Zorrilla³, Edurne Guerrero Basterretxea³, Esther Ruíz Lucea⁵, Ignacio Torre Salaberri⁶, Lidia Estopiñán-Fortea³, Catalina Gómez Arango⁷ and Amaia Bilbao-González⁸, ¹Rheumatology Department, Basurto University Hospital, VITORIA, Spain, ²Rheumatology, Rheumatology Department, Basurto University Hospital, VITORIA, Spain, ³Rheumatology Department, Basurto University Hospital, Bilbao, Spain, ⁴Rheumatology Department, Basurto University Hospital, BILBAO, Spain, ⁵Rheumatology Department, Basurto University Hospital., Bilbao, Spain, ⁶Rheumatology, Hospital Universitario de Basurto. Bilbao., Bilbao, Spain, ⁷Rheumatology, Rheumatology Department, Basurto University Hospital, Bilbao, Spain, ⁸Research Department, Basurto University Hospital, Bilbao, Spain
Background/Purpose: Osteoporosis (OP) in males under 70 years is less common than postmenopausal and senile, but generates significant social and health costs associated with morbidity…
Abstract Number: 228 • 2015 ACR/ARHP Annual Meeting
Gout and Risk of Non-Vertebral Osteoporotic Fracture
Seoyoung C. Kim¹, Julie M. Paik², Jun Liu³, Gary C. Curhan² and Daniel H. Solomon⁴, ¹Div. of Pharmacoepidemiology and Pharmacoeconomics, Div. of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Renal Division, Brigham and Women's Hospital, Boston, MA, ³Division of Pharmaoepidemiology, Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Prior studies suggest an association between osteoporosis, systemic inflammation and pro-inflammatory cytokines such as IL-1 and IL-6. Gout is a common inflammatory arthritis characterized…
Abstract Number: 353 • 2015 ACR/ARHP Annual Meeting
A Longitudinal Cohort Study of Weekly Teriparatide, Denosmab, and Bisphosphonates for Prevention of Vertebral Fractures in Glucocorticoid-Induced Osteoporosis
Hisaji Oshima¹, Mari Ushikubo¹, Kumiko Akiya¹, Ikuko Tanaka², Shigenori Tamaki² and Keisuke Izumi³, ¹Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ²NAGOYA Rheumatology Clinic, Nagoya, Japan, ³National Tokyo Medical Center, Tokyo, Japan
Background/Purpose: Although weekly teriparatide (56.5ug, wTPTD) and denosmab (DMAB) have been developed as potent anti-osteoporotic agents, effects of these agents on prevention of osteoporotic fractures…
Abstract Number: 364 • 2015 ACR/ARHP Annual Meeting
Very High Frequency of Fragility Fractures Associated with High-Dose Glucocorticoids in Postmenopausal Women: A Retrospective Study
Goichi Kageyama¹, Takaichi Okano¹, Yuzuru Yamamoto¹, Keisuke Nishimura¹, Daisuke Sugiyama², Jun Saegusa¹, Goh Tsuji³, Shunichi Kumagai⁴ and Akio Morinobu¹, ¹Department of Rheumatology, Kobe University Hospital, Kobe, Japan, ²Department of Preventive Medicine and Public Health, Keio University, Tokyo, Japan, ³The Center for Rheumatic Diseases, Shinko Hospital, Kobe, Japan, ⁴The Center of Rheumatic Diseases, Shinko Hospital, Kobe, Japan
Background/Purpose: To evaluate the incidence of fragility fractures associated with high-dose glucocorticoid therapy in patients with systemic rheumatic disease.Methods: A retrospective study of patients who were treated with high-dose…
Abstract Number: 369 • 2015 ACR/ARHP Annual Meeting
Incidence of Fragility Hip Fractures over 10 Years (2004-13) in Three UK Centres with Reference to Local Fracture Prevention (‘fracture liaison’) Service Activity
Gavin Clunie¹ and Jonathan Belsey², ¹Rheumatology, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom, ²JB Medical, Sudbury, United Kingdom
Background/Purpose: Fracture Liaison Services systematically identify patients with fragility fracture and screen patients for osteoporosis and associated conditions and instigate evidence-based 'secondary' fracture prevention management.…
Abstract Number: 373 • 2015 ACR/ARHP Annual Meeting
Compared to Non-Users, Current Glucocorticoids Users Have Less Prevalent Fractures at the Same Bone Mass: Results of a Large Cross-Sectional Study
Marwan Bukhari¹, Nicola Goodson^2,3 and Maarten Boers⁴, ¹Rheumatology, Royal Lancaster Infirmary, Consultant and Honorary Senior Lecturer, Lancaster, United Kingdom, ²Rheumatology, University of Liverpool, Liverpool, United Kingdom, ³Rheumatology, University Hospital Aintree, Liverpool, United Kingdom, ⁴Amsterdam Rheumatology and Immunology Center, VU University Medical center, Amsterdam, Netherlands
Background/Purpose: It is widely believed that use of glucocorticoids (GC) increase risk of fracture through reduction in bone quality as well as reduction in bone…
Abstract Number: 378 • 2015 ACR/ARHP Annual Meeting
Osteoporotic Fragility Tibia/Fibula Fractures Are Not Asociated with a Low Body Mass Index: An Observational Study
Vishnu Kammath¹ and Marwan Bukhari², ¹Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom, ²Rheumatology, Royal Lancaster Infirmary, Consultant and Honorary Senior Lecturer, Lancaster, United Kingdom
Background/Purpose: Tibia/Fibula (Tib/Fib) fractures are one of osteoporotic fragility fractures. They have been suggested to be more likely to occur secondary to osteoporosis (OP) than…
Abstract Number: 2233 • 2015 ACR/ARHP Annual Meeting
Predictors of Imminent Fracture Risk in Women Aged >=65 Years with Osteoporosis
Derek Weycker¹, Richard Barron², Alex Kartashov¹, John Edelsberg¹, DB Crittenden³ and A Grauer³, ¹Policy Analysis Inc. (PAI), Brookline, MA, ²Amgen, Inc., Thousand Oaks, CA, ³Amgen Inc., Thousand Oaks, CA
Background/Purpose: Fractures are the major source of morbidity among women with osteoporosis. However, evidence on factors leading to imminent risk for hip or other non-vertebral…
Abstract Number: 224 • 2014 ACR/ARHP Annual Meeting
Is the Protective Effect of Obesity Against Hip Fracture Due to Changes of Proximal Femur Shape?
Alexander Oldroyd¹ and Marwan Bukhari^1,2, ¹Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, ²Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom
Background/Purpose: The association between increasing body mass index (BMI), increasing bone mineral density (BMD) and lower hip fracture risk has been demonstrated by previous research. Studies…
Abstract Number: 223 • 2014 ACR/ARHP Annual Meeting
Risk Factors for Clinical Vertebral Fractures in Japanese Men and Women with Rheumatoid Arthritis: Results from a Large Prospective Observational Cohort Study
Osamu Ishida¹, Takefumi Furuya², Eisuke Inoue³, Kensuke Ochi², Katsunori Ikari², Atsuo Taniguchi⁴, Hisashi Yamanaka² and Shigeki Momohara⁴, ¹Orthopedics, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ³Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, ⁴Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan
Background/Purpose: Patients with rheumatoid arthritis (RA) are at high risk of developing vertebral fractures. Previously, utilizing data from our Institute of Rheumatology Rheumatoid Arthritis (IORRA)…
Abstract Number: 2047 • 2014 ACR/ARHP Annual Meeting
No Association of Serum Uric Acid with Hip Fracture Risk in Older Men and Women from the Framingham Original Cohort
Shivani Sahni¹, Kelsey Mangano², Katherine Tucker³, Caroline Fox⁴, Douglas P. Kiel⁵, Xiaochun Zhang⁶ and Marian T. Hannan¹, ¹Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, ²Musculoskeletal Research, Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, ³Clinical Laboratory & Nutritional Sciences, Center for Population Health & Health Disparities, University of Massachusetts, Lowell, MA, ⁴Institute of Genetics and Biophysics, NHLBI's Framingham Heart Study and Center for Population Studies, Framingham, MA, ⁵Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, ⁶Musculoskeletal Research, Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA
Background/Purpose: Serum uric acid (UA) has been linked with fractures in older men. Three different studies in older men showed conflicting results. The objective…
Abstract Number: 2004 • 2014 ACR/ARHP Annual Meeting
Osteoporosis Screening and Fracture Risk Assessment Tool Usage Among House Staff
Jordan Brodsky¹, Meghan Greenfield² and Erin Patton³, ¹Medicine, Albert Einstein College of Medicine, Woodmere, NY, ²279 E 10th St, Beth Israel Medical Center, New York, NY, ³Rheumatology, Beth Israel Medical Center, New York, NY
Background/Purpose: Despite increased awareness of the magnitude and consequences of osteoporosis and the availability of recommendations for screening and treatment by multiple organizations, osteoporosis is…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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