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Abstracts tagged "Fracture risk"

  • Abstract Number: 2808 • 2018 ACR/ARHP Annual Meeting

    T-Score As an Indicator of Fracture Risk on Therapy: Evidence from Romosozumab Vs Alendronate Treatment in the Active-Controlled Fracture Study in Postmenopausal Women with Osteoporosis at High Risk Trial

    Felicia Cosman1, E. Michael Lewiecki2, Peter R Ebeling3, Eric Hesse4, Nicola Napoli5, Daria B Crittenden6, Maria Rojeski6, Wenjing Yang6, Cesar Libanati7 and Serge Ferrari8, 1Columbia University, New York, NY, 2New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, 3Monash University, Melbourne, Australia, 4University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 5Campus Bio-Medico University of Rome, Rome, Italy, 6Amgen Inc., Thousand Oaks, CA, 7UCB Pharma, Brussels, Belgium, 8Geneva University Hospital, Geneva, Switzerland

    Background/Purpose: BMD is a strong predictor of fracture risk in untreated patients. Recent evidence suggests that BMD achieved during treatment also reflects fracture risk; thus,…
  • Abstract Number: 1223 • 2017 ACR/ARHP Annual Meeting

    Inflammatory Bowel Diseases and the Risks of Fracture and Low Mineral Density: Review of the Literature and Meta-Analysis of Observational Cohorts

    Paulina Szafors1, Thomas Barnetche2, Cédric Lukas3, Jacques Morel4, Cécile Gaujoux-Viala5,6, Bernard Combe7 and Hélène Che8, 1Department of Rheumatology, Lapeyronie Hospital and University of Montpellier, Montpellier, France, 2Rheumatology Department, Pellegrin University Hospital, BORDEAUX, France, 3Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, 4Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 5Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France, 6EA 2415, Montpellier University, Nîmes, France, 7Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France, 8Rheumatology, University and Hospital Lapeyronie, University of Montpellier, France

    Background/Purpose:   Inflammatory bowel diseases (IBD), such as Crohn disease (CD) and ulcerative colitis (UC), are associated with a decreased bone mineral density caused by chronic…
  • Abstract Number: 1227 • 2017 ACR/ARHP Annual Meeting

    Osteoporosis and Breast Cancer: Can FRAX-Based Risk Factors Accurately Predict Further Fractures at This Setting?

    Salvador López-Salguero1, Laura Ranieri2, Juan Carlos Ordoñez3, Mariano Andrés4,5, Jose Ponce6 and Isabel Ibero2, 1Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain, 2Reumatología, Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 3RHEUMATOLOGY, Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 4Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 5Universidad Miguel Hernández, Elche, Spain, 6Oncología, Dpt. Oncology, Hospital General Universitario Alicante, Alicante, Spain

    Background/Purpose: Women with breast cáncer (BC) are at risk for the development of bone loss and osteoporosis (OP) mainly due to adjuvant therapies, as aromatase…
  • Abstract Number: 2783 • 2017 ACR/ARHP Annual Meeting

    Medications Associated with Osteoporotic Fracture Risk in Patients with Rheumatoid Arthritis

    Gulsen Ozen1, Sofia Pedro2, Frederick Wolfe2 and Kaleb Michaud1, 1Rheumatology, University of Nebraska Medical Center, Omaha, NE, 2National Data Bank for Rheumatic Diseases, Wichita, KS

    Background/Purpose: Osteoporotic (OP) fractures are a major cause of disability, cost, and mortality in RA. Besides increased OP fracture risk, chronic inflammation and pain predispose…
  • Abstract Number: 326 • 2017 ACR/ARHP Annual Meeting

    Osteoporosis and Vertebral Fractures Are Associated with Disease Activity, Low Vitamin D Levels and Spinal Radiographic Damage in Patients with Axial Spondyloarthritis

    Cintia Romera-López1, Cristina Fernández-Carballido2, Miguel Ángel García-Moreno3 and Teresa Pedraz4, 1Rheumatology, Hospital Universitario del Vinalopó, Elche, Spain, 2Hospital General Universitario de Elda, Elda, Spain, 3Hosppital Universitario de Elda, Elda, Spain, 4Hospital Universitario de Elda, Elda, Spain

    Background/Purpose: Osteoporosis and vertebral fractures are comorbidities of Axial Spondyloarthritis (axSpA). We evaluated the relationship between disease activity and radiographic damage and bone mineral density…
  • Abstract Number: 328 • 2017 ACR/ARHP Annual Meeting

    Secular Trends in the Risk of Fragility Fracture Among Patients with Rheumatoid Arthritis: A General Population-Based Study

    Sarah Keller1, Marcy B. Bolster2, Amar Oza3, Sharan K. Rai4, Leo Lu3, Yuqing Zhang5 and Hyon K. Choi4, 1Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Allergy, Immunology, and Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 5Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The risk of osteoporotic (OP) fracture among patients with rheumatoid arthritis (RA) is higher than that of the general population. The worldwide incidence of…
  • Abstract Number: 1218 • 2017 ACR/ARHP Annual Meeting

    Caffeine Consumption and Risk of Osteoporosis: A Cross Sectional Study of 3, 210 Patients from the National Health and Nutrition Examination Survey

    Nicola Berman1, Teresa Attina2, Bruce Cronstein1, Stephen Honig1 and Michael Pillinger1, 1Rheumatology, New York University School of Medicine, Division of Rheumatology, New York, NY, 2Pediatrics, New York University School of Medicine, New York, NY

    Background/Purpose: Adenosine regulates bone metabolism. In vitro studies suggest that direct stimulation of the adenosine A2A receptor increases osteoblasts and diminishes osteoclasts, and thus inhibition…
  • Abstract Number: 327 • 2016 ACR/ARHP Annual Meeting

    Drug Retention Rate of Oral Bisphosphonate in Patients with Rheumatoid Arthritis

    Ji-Heh Park1, Seung-Geun Lee1, Eun-Kyoung Park2, Hee-Sang Tag3 and Geun-Tae Kim4, 1Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea, The Republic of, 2Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea, The Republic of, 3Division of Rheumatology, Department of Internal Medicine, Kosin University College of Medicine, Busan, South Korea, 4Kosin University College of Medicine, Busan, South Korea

    Background/Purpose: As rheumatoid arthritis (RA) is a well-established risk factor for osteoporosis and compression fracture, non-adherence to bisphosphonate (BP) therapy in patients with RA can…
  • Abstract Number: 331 • 2016 ACR/ARHP Annual Meeting

    Biologic Disease-Modifying Anti-Rheumatic Drug Use and the Risk of Non-Vertebral Osteoporotic Fractures in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Study

    Takefumi Furuya1, Eisuke Inoue1,2, Masanori Nakayama1, Eiichi Tanaka1, Katsunori Ikari1, Ayako Nakajima3, Atsuo Taniguchi1 and Hisashi Yamanaka1, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Center for Clinical Research and Development, National Center for Child Health and Development, Tokyo, Japan, 3Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose:   Previous U.S. and Canadian studies [1-3] have suggested that no significant associations exist between use of biologic disease-modifying anti-rheumatic drugs (DMARDs) and risk of…
  • Abstract Number: 334 • 2016 ACR/ARHP Annual Meeting

    Predictors of Fragility Fractures in Patients with Rheumatoid Arthritis Not on Steroids: An Observational Study

    Sarah Dyball1 and Marwan Bukhari2, 1University Hospital South Manchester, Manchester, United Kingdom, 2Royal Lancaster Infirmary, Lancaster, United Kingdom

    Background/Purpose:   Patients with rheumatoid arthritis (RA) have an increased fracture risk, however, this is confounded by a coexisting use of steroids. This study aims…
  • Abstract Number: 338 • 2016 ACR/ARHP Annual Meeting

    Abaloparatide-SC Significantly Reduces Vertebral and Nonvertebral Fractures and Increases Bone Mineral Density (BMD) Regardless of Age, BMD T-Score, or Prior Fracture at Baseline

    F Cosman1, Gary Hattersley2, PD Miller3, Ming-Yu Hu4, Luis Augusto Tavares Russo5, Bente Riis6, Greg Williams7 and Lorraine Fitzpatrick8, 1Clinical Research Center, Helen Hayes Hospital, West Haverstraw, NY, 2Research, Radius Health, Inc., Waltham, MA, 3Colorado Center for Bone Research, Lakewood, CO, 4Biometrics, Radius Health, Inc., Waltham, MA, 5CCBR Brasil, Rua Mena Barreto, 33 Botofogo, 22271, Rio de Janeiro, Brazil, 6Nordic Biosciences A/S, 2730 Herlev, Denmark, 7Clinical Development, Radius Health, Inc., Waltham, MA, 8Chief Medical Officer, Radius Health, Inc., Waltham, MA

    Background/Purpose:  Abaloparatide is a novel 34 amino acid peptide created to be a potent and selective activator of the PTH 1 receptor signaling pathway and…
  • Abstract Number: 344 • 2016 ACR/ARHP Annual Meeting

    Is Rheumatoid Arthritis a Risk Factor for Fractures: A Systematic Review of Observational Studies

    Ambika Gupta1, Stephanie Pipe2, Tanveer Towheed3 and Tassos Anastassiades2, 1Internal Medicine, Queen's University, Kingston, ON, Canada, 2Queen's University, Kingston, ON, Canada, 3Dept of Medicine, Queen's University, Kingston, ON, Canada

    Background/Purpose: Rheumatoid Arthritis (RA) is a known risk factor for osteoporosis. There are many factors that contribute to this increased risk, including the use of…
  • Abstract Number: 355 • 2016 ACR/ARHP Annual Meeting

    Fracture Incidence Rates in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis

    Raveendhara R. Bannuru1, Elizaveta Vaysbrot2, Mikala Osani2, Lenore Buckley3, Howard Fink4 and Timothy E. McAlindon5, 1Rheumatology, Tufts Med Ctr, Boston, MA, 2Rheumatology, Tufts Medical Center, Boston, MA, 3Rheumatology, Yale University, North Haven, CT, 4Minneapolis VA Health Care System, Washington, DC, 5Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: Transplants increase risk of bone loss and fractures and reduce quality of life. Information on fracture incidence is important when making clinical decisions about…
  • Abstract Number: 356 • 2016 ACR/ARHP Annual Meeting

    Osteoporotic Fracture As the Main Risk Factor in the Detection of Osteoporosis in Men Under 70 Years

    JUAN MARIA BLANCO MADRIGAL1,2, MARIA LUZ GARCIA VIVAR3, Eva Galindez-Agirregoikoa3, OLAIA BEGOÑA FERNANDEZ BERRIZBEITIA4, Itziar Calvo Zorrilla3, Edurne Guerrero Basterretxea3, Esther Ruíz Lucea5, Ignacio Torre Salaberri6, Lidia Estopiñán-Fortea3, Catalina Gómez Arango7 and Amaia Bilbao-González8, 1Rheumatology Department, Basurto University Hospital, VITORIA, Spain, 2Rheumatology, Rheumatology Department, Basurto University Hospital, VITORIA, Spain, 3Rheumatology Department, Basurto University Hospital, Bilbao, Spain, 4Rheumatology Department, Basurto University Hospital, BILBAO, Spain, 5Rheumatology Department, Basurto University Hospital., Bilbao, Spain, 6Rheumatology, Hospital Universitario de Basurto. Bilbao., Bilbao, Spain, 7Rheumatology, Rheumatology Department, Basurto University Hospital, Bilbao, Spain, 8Research Department, Basurto University Hospital, Bilbao, Spain

    Background/Purpose: Osteoporosis (OP) in males under 70 years is less common than postmenopausal and senile, but generates significant social and health costs associated with morbidity…
  • Abstract Number: 1181 • 2016 ACR/ARHP Annual Meeting

    Risk Factors for Incident Fractures in Patients with Systemic Lupus Erythematosus on Dialysis

    Brian Le1,2, Jennifer Waller3, Reshmitha Radhakrishnan4, Sun Jung Oh4, Monique Bethel2,5, Christopher Rice4 and Laura Carbone2,6, 1Department of Internal Medicine, Augusta University, Augusta, GA, 2Specialty Care, Charlie Norwood VA Medical Center, Augusta, GA, 3Biostatistics, Augusta University, Augusta, GA, 4School of Medicine, Augusta University, Augusta, GA, 51120 15th Street, BI 5070, Augusta University, Augusta, GA, 6Rheumatology, Augusta University, Augusta, GA

    Background/Purpose:  Osteoporosis and osteoporotic fractures are significant comorbidities in patients with systemic lupus erythematosus (SLE). Hip fractures are being increasingly recognized as a complication of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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