Abstracts tagged "flare"

Abstract Number: 0896 • ACR Convergence 2021
Systemic Lupus Erythematosus Disease Flares After SARS-CoV-2 Vaccination
Medha Barbhaiya¹, Jonah Levine¹, Caroline Siegel¹, Vivian Bykerk², Deanna Jannat-Khah¹ and Lisa Mandl¹, ¹Hospital for Special Surgery, New York, NY, ²Division of Rheumatology, Hospital for Special Surgery, New York City, NY
Background/Purpose: Vaccination against SARS-CoV-2 is particularly important for patients with systemic lupus erythematosus (SLE), who may be at increased risk of hospitalization for COVID-19. However,…
Abstract Number: 0929 • ACR Convergence 2021
Tapering of TNF Inhibitors in Patients with Axial Spondyloartritis – Can Flare Be Predicted?
Marie Wetterslev¹, Stylianos Georgiadis², Sara Nysom Christiansen³, Susanne Juhl Pedersen², Inge Juul Sørensen⁴, Merete Lund Hetland¹, Anne Duer⁵, Mikael Boesen⁶, Kasper Kjærulf Gosvig⁷, Jakob Møllenbach Møller⁷, Mads Bakkegaard⁸, Cecilie Heegaard Brahe², Niels Steen Krogh⁹, Bente Jensen⁸, Ole Rintek Madsen⁸, Jan Christensen⁸, Annette Hansen⁸, Jesper Nørregaard⁸, Henrik Røgind⁸ and Mikkel Ostergaard¹⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ⁴Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ⁵Department of Radiology, Rigshospitalet, Glostrup, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ⁷Department of Radiology, Herlev and Gentofte Hospital, Copenhagen, Denmark, ⁸Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ⁹ZiteLab ApS, Copenhagen, Denmark, Frederiksberg, Denmark, ¹⁰Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark
Background/Purpose: Patients with axial spondyloarthritis (axSpA) in clinical remission tapered Tumor Necrosis Factor inhibitor (TNFi) treatment according to a clinical guideline and were followed for…
Abstract Number: 1274 • ACR Convergence 2021
Severe Flares Are Associated with a Poorer Health-Related Quality of Life (HRQoL) in Systemic Lupus Erythematosus (SLE) Patients
Manuel Ugarte-Gil¹, Rocio Gamboa-Cardenas², Cristina Reategui-Sokolova³, Victor Pimentel-Quiroz¹, Mariela Medina⁴, Claudia Elera-Fitzcarrald², Francisco Zevallos⁴, Cesar Pastor-Asurza⁵, Federico Zazzetti⁶, Chetan Karyekar⁷, Risto Perich-Campos⁵ and Graciela Alarcn⁸, ¹Hospital Guillermo Almenara Irigoyen, Essalud/Universidad Científica del Sur, Lima, Peru, ²Universidad Cientifica del Sur/Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ³Hospital Guillermo Almenara Irigoyen, Lima, Peru, ⁴Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ⁵Universidad Nacional Mayor de San Marcos/Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ⁶Medical Affairs, Jan-Cil Argentina, Buenos Aires, Argentina, ⁷Janssen R&D, Spring House, PA, ⁸University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Flares in SLE patients, regardless of their severity, have been associated with damage accrual. However, their impact on HRQoL has not been fully evaluated.…
Abstract Number: 1603 • ACR Convergence 2021
COVID-19 Vaccination Experience in Patients with Rheumatoid Arthritis Treated at the Cleveland VA Medical Center
Sarah Abi Doumeth¹, Laura Silversteyn², Donald Anthony² and Maya Mattar³, ¹University hospitals Cleveland medical center, Cleveland, OH, ²Louis Stokes Cleveland VA Medical Center, Cleveland, OH, ³Louis Stokes VA Medical Center, Mayfield Heights, OH
Background/Purpose: Following the introduction of the COVID-19 vaccines, there has been uncertainty as to whether receiving the COVID-19 vaccine would result in overactivation of the…
Abstract Number: 1893 • ACR Convergence 2021
“From Where I Stand”: Using Multiple Anchors Yields Different Benchmarks for Meaningful Improvement and Worsening in the Rheumatoid Arthritis Flare Questionnaire (RA-FQ)
Susan Bartlett¹, Vivian Bykerk², Orit Schieir³, Marie-France Valois¹, Louis Bessette⁴, Gilles Boire⁵, Glen Hazlewood⁶, Carol Hitchon⁷, Edward Keystone⁸, Janet Pope⁹, Diane Tin¹⁰, Carter Thorne¹¹, Clifton Bingham¹² and CATCH Investigators¹³, ¹McGill University, Montréal, QC, Canada, ²Hospital for Special Surgery, New York, NY, ³Canadian Early Arthritis Cohort Study, Montréal, QC, Canada, ⁴Centre de l'Ostoporose et de Rhumatologie de Qubec, Québec City, QC, Canada, ⁵Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁶University of Calgary, Calgary, AB, Canada, ⁷University of Manitoba, Winnipeg, MB, Canada, ⁸Keystone Consulting Enterprises Inc., Toronto, ON, Canada, ⁹University of Western Ontario, London, ON, Canada, ¹⁰The Arthritis Program Research Group, Newmarket, ON, Canada, ¹¹Southlake Regional Health Centre, Newmarket, ON, Canada, ¹²Johns Hopkins University, Baltimore, MD, ¹³Canadian Early Arthritis Cohort Investigators, Toronto, ON, Canada
Background/Purpose: The RA-FQ is a patient-reported measure of current disease activity in RA that can be used to identify disease flares. The RA-FQ queries pain,…
Abstract Number: 114 • 2019 ACR/ARP Annual Meeting
Persistent Synovial Resident Memory T Cells Mediate Arthritis Flares
Margaret Chang¹, Anaïs Levescot ², Rachel Blaustein ², Nathan Nelson-Maney ², Allyn Morris ², Robert Fuhlbrigge ³ and Peter Nigrovic ⁴, ¹Division of Immunology, Boston Children's Hospital, Boston, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, ³Department of Rheumatology, Children’s Hospital Colorado, Denver, CO, ⁴Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA ; Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA., Boston
Background/Purpose: Resident memory T cells (TRM) are site-specific memory T cells that take up long-term residence in peripheral tissues and aid in pathogen defense. However,…
Abstract Number: 1025 • 2019 ACR/ARP Annual Meeting
Dynamic Changes During SLE Flare Implicate Age-Associated B Cells and Altered T Follicular and Peripheral Helper Cell Responses in Disease Activity
Kieran Manion¹, Zahi Touma ², Dennisse Bonilla ², Dafna Gladman ³, Murray Urowitz ² and Joan Wither ⁴, ¹Krembil Research Institute, Toronto, ON, Canada, ²University Health Network, University of Toronto, Toronto, ON, Canada, ³Krembil Research Institute, U of Toronto, Toronto, ON, Canada, ⁴University Health Network, Krembil Research Institute, Toronto, ON, Canada
Background/Purpose: SLE is a chronic autoimmune disorder in which periods of relative disease inactivity are punctuated by flares that present with increased inflammation and tissue…
Abstract Number: 1135 • 2019 ACR/ARP Annual Meeting
Optimizing the Management of Flares in Patients with Rheumatoid Arthritis with the Help of Non-Physician Providers: Results of a Randomized Controlled Trial
Elena Myasoedova¹, Cynthia Crowson ², Rachel Giblon ¹, Kathleen McCarthy-Fruin ¹, Daniel Schaffer ¹, Kerry Wright ¹, Eric Matteson ³ and John Davis ¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic Rochester, Rochester, ³Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, Rochester
Background/Purpose: Flares in rheumatoid arthritis (RA) are common. The shortage of readily available specialized care may hinder early detection and timely management of RA flares.…
Abstract Number: 2567 • 2019 ACR/ARP Annual Meeting
Prospective Evaluation of American Academy of Ophthalmology Low Dose Hydroxychloroquine Recommendation in Stable Lupus Nephritis with High-Risk Retinopathy: Lipid Profile and Flare Rates
Tatiana Pedrosa ¹, Sandra G. Pasoto ¹, Emily Yuki², Nadia Aikawa ¹, Eduardo Borba ¹, Julio Ferreira Filho ¹, Pedro Carricondo ³, Caio Zanetti ¹, Paola Conde ¹, Nicole Fontoura ¹, Paschoalina Romano ⁴, Valdemir Carvalho ⁵, Clovis Silva ⁶ and Eloisa Bonfa ⁷, ¹Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, ²Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., São Paulo, Brazil, ³Ophtalmology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, ⁴Division of Central Laboratory, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, ⁵Fleury Group, Sao Paulo, Brazil, Sao Paulo, Brazil, ⁶Pediatric Rheumatology Unit, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, ⁷Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Sao Paulo, Brazil
Background/Purpose: Hydroxychloroquine (HCQ) is the most well established therapy for SLE, as it provides several beneficial properties, such as favorable effects on lipid profile, reduced…