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Abstracts tagged "flare"

  • Abstract Number: 0896 • ACR Convergence 2021

    Systemic Lupus Erythematosus Disease Flares After SARS-CoV-2 Vaccination

    Medha Barbhaiya1, Jonah Levine1, Caroline Siegel1, Vivian Bykerk2, Deanna Jannat-Khah1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2Division of Rheumatology, Hospital for Special Surgery, New York City, NY

    Background/Purpose: Vaccination against SARS-CoV-2 is particularly important for patients with systemic lupus erythematosus (SLE), who may be at increased risk of hospitalization for COVID-19. However,…
  • Abstract Number: 0929 • ACR Convergence 2021

    Tapering of TNF Inhibitors in Patients with Axial Spondyloartritis – Can Flare Be Predicted?

    Marie Wetterslev1, Stylianos Georgiadis2, Sara Nysom Christiansen3, Susanne Juhl Pedersen2, Inge Juul Sørensen4, Merete Lund Hetland1, Anne Duer5, Mikael Boesen6, Kasper Kjærulf Gosvig7, Jakob Møllenbach Møller7, Mads Bakkegaard8, Cecilie Heegaard Brahe2, Niels Steen Krogh9, Bente Jensen8, Ole Rintek Madsen8, Jan Christensen8, Annette Hansen8, Jesper Nørregaard8, Henrik Røgind8 and Mikkel Ostergaard10, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, 2Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 3Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, 4Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, 5Department of Radiology, Rigshospitalet, Glostrup, Copenhagen, Denmark, 6Department of Radiology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, 7Department of Radiology, Herlev and Gentofte Hospital, Copenhagen, Denmark, 8Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 9ZiteLab ApS, Copenhagen, Denmark, Frederiksberg, Denmark, 10Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark

    Background/Purpose: Patients with axial spondyloarthritis (axSpA) in clinical remission tapered Tumor Necrosis Factor inhibitor (TNFi) treatment according to a clinical guideline and were followed for…
  • Abstract Number: 1274 • ACR Convergence 2021

    Severe Flares Are Associated with a Poorer Health-Related Quality of Life (HRQoL) in Systemic Lupus Erythematosus (SLE) Patients

    Manuel Ugarte-Gil1, Rocio Gamboa-Cardenas2, Cristina Reategui-Sokolova3, Victor Pimentel-Quiroz1, Mariela Medina4, Claudia Elera-Fitzcarrald2, Francisco Zevallos4, Cesar Pastor-Asurza5, Federico Zazzetti6, Chetan Karyekar7, Risto Perich-Campos5 and Graciela Alarcn8, 1Hospital Guillermo Almenara Irigoyen, Essalud/Universidad Científica del Sur, Lima, Peru, 2Universidad Cientifica del Sur/Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 3Hospital Guillermo Almenara Irigoyen, Lima, Peru, 4Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 5Universidad Nacional Mayor de San Marcos/Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 6Medical Affairs, Jan-Cil Argentina, Buenos Aires, Argentina, 7Janssen R&D, Spring House, PA, 8University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Flares in SLE patients, regardless of their severity, have been associated with damage accrual. However, their impact on HRQoL has not been fully evaluated.…
  • Abstract Number: 1603 • ACR Convergence 2021

    COVID-19 Vaccination Experience in Patients with Rheumatoid Arthritis Treated at the Cleveland VA Medical Center

    Sarah Abi Doumeth1, Laura Silversteyn2, Donald Anthony2 and Maya Mattar3, 1University hospitals Cleveland medical center, Cleveland, OH, 2Louis Stokes Cleveland VA Medical Center, Cleveland, OH, 3Louis Stokes VA Medical Center, Mayfield Heights, OH

    Background/Purpose: Following the introduction of the COVID-19 vaccines, there has been uncertainty as to whether receiving the COVID-19 vaccine would result in overactivation of the…
  • Abstract Number: 1893 • ACR Convergence 2021

    “From Where I Stand”: Using Multiple Anchors Yields Different Benchmarks for Meaningful Improvement and Worsening in the Rheumatoid Arthritis Flare Questionnaire (RA-FQ)

    Susan Bartlett1, Vivian Bykerk2, Orit Schieir3, Marie-France Valois1, Louis Bessette4, Gilles Boire5, Glen Hazlewood6, Carol Hitchon7, Edward Keystone8, Janet Pope9, Diane Tin10, Carter Thorne11, Clifton Bingham12 and CATCH Investigators13, 1McGill University, Montréal, QC, Canada, 2Hospital for Special Surgery, New York, NY, 3Canadian Early Arthritis Cohort Study, Montréal, QC, Canada, 4Centre de l'Ostoporose et de Rhumatologie de Qubec, Québec City, QC, Canada, 5Universite de Sherbrooke, Sherbrooke, QC, Canada, 6University of Calgary, Calgary, AB, Canada, 7University of Manitoba, Winnipeg, MB, Canada, 8Keystone Consulting Enterprises Inc., Toronto, ON, Canada, 9University of Western Ontario, London, ON, Canada, 10The Arthritis Program Research Group, Newmarket, ON, Canada, 11Southlake Regional Health Centre, Newmarket, ON, Canada, 12Johns Hopkins University, Baltimore, MD, 13Canadian Early Arthritis Cohort Investigators, Toronto, ON, Canada

    Background/Purpose: The RA-FQ is a patient-reported measure of current disease activity in RA that can be used to identify disease flares. The RA-FQ queries pain,…
  • Abstract Number: 114 • 2019 ACR/ARP Annual Meeting

    Persistent Synovial Resident Memory T Cells Mediate Arthritis Flares

    Margaret Chang1, Anaïs Levescot 2, Rachel Blaustein 2, Nathan Nelson-Maney 2, Allyn Morris 2, Robert Fuhlbrigge 3 and Peter Nigrovic 4, 1Division of Immunology, Boston Children's Hospital, Boston, 2Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, 3Department of Rheumatology, Children’s Hospital Colorado, Denver, CO, 4Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA ; Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA., Boston

    Background/Purpose: Resident memory T cells (TRM) are site-specific memory T cells that take up long-term residence in peripheral tissues and aid in pathogen defense. However,…
  • Abstract Number: 1025 • 2019 ACR/ARP Annual Meeting

    Dynamic Changes During SLE Flare Implicate Age-Associated B Cells and Altered T Follicular and Peripheral Helper Cell Responses in Disease Activity

    Kieran Manion1, Zahi Touma 2, Dennisse Bonilla 2, Dafna Gladman 3, Murray Urowitz 2 and Joan Wither 4, 1Krembil Research Institute, Toronto, ON, Canada, 2University Health Network, University of Toronto, Toronto, ON, Canada, 3Krembil Research Institute, U of Toronto, Toronto, ON, Canada, 4University Health Network, Krembil Research Institute, Toronto, ON, Canada

    Background/Purpose: SLE is a chronic autoimmune disorder in which periods of relative disease inactivity are punctuated by flares that present with increased inflammation and tissue…
  • Abstract Number: 1135 • 2019 ACR/ARP Annual Meeting

    Optimizing the Management of Flares in Patients with Rheumatoid Arthritis with the Help of Non-Physician Providers: Results of a Randomized Controlled Trial

    Elena Myasoedova1, Cynthia Crowson 2, Rachel Giblon 1, Kathleen McCarthy-Fruin 1, Daniel Schaffer 1, Kerry Wright 1, Eric Matteson 3 and John Davis 1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic Rochester, Rochester, 3Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, Rochester

    Background/Purpose: Flares in rheumatoid arthritis (RA) are common. The shortage of readily available specialized care may hinder early detection and timely management of RA flares.…
  • Abstract Number: 2567 • 2019 ACR/ARP Annual Meeting

    Prospective Evaluation of American Academy of Ophthalmology Low Dose Hydroxychloroquine Recommendation in Stable Lupus Nephritis with High-Risk Retinopathy: Lipid Profile and Flare Rates

    Tatiana Pedrosa 1, Sandra G. Pasoto 1, Emily Yuki2, Nadia Aikawa 1, Eduardo Borba 1, Julio Ferreira Filho 1, Pedro Carricondo 3, Caio Zanetti 1, Paola Conde 1, Nicole Fontoura 1, Paschoalina Romano 4, Valdemir Carvalho 5, Clovis Silva 6 and Eloisa Bonfa 7, 1Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, 2Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., São Paulo, Brazil, 3Ophtalmology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, 4Division of Central Laboratory, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, 5Fleury Group, Sao Paulo, Brazil, Sao Paulo, Brazil, 6Pediatric Rheumatology Unit, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, 7Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Sao Paulo, Brazil

    Background/Purpose: Hydroxychloroquine (HCQ) is the most well established therapy for SLE, as it provides several beneficial properties, such as favorable effects on lipid profile, reduced…
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