Abstracts tagged "Erosions"

Abstract Number: 2614 • ACR Convergence 2025
Impact of Vagus Nerve-Mediated Neuroimmune Modulation on structural joint damage using Gd-MRI RAMRIS imaging in Biologic-Experienced Patients with Rheumatoid Arthritis
Charles Peterfy, MD, PhD¹, John Tesser², Yaakov Levine³, Melissa Evangelista⁴, Vibeke Strand⁵, Michael Weinblatt⁶ and David Chernoff⁷, ¹Spire Sciences, Inc., Boca Raton, FL, ²Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, ³SetPoint Medical, Valencia, CA, ⁴SetPoint Medical Corporation, Valencia, CA, ⁵Stanford University School of Medicine, Palo Alto CA, Portola Valley, CA, ⁶Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, ⁷SetPoint Medical, Sausalito, CA
Background/Purpose: Previously reported results from RESET-RA (ClinicalTrials.gov, NCT04539964) showed neuroimmune modulation via electrical stimulation of the left vagus nerve using an implantable device to treat…
Abstract Number: 1943 • ACR Convergence 2025
Searching for subclinical synovitis and erosions in seropositive palindromic rheumatism: the added value of the ultrasonographic study of feet
Andrés Ponce¹, Cynthia Vanesa del Valle Rojas², nuria Sapena³, Georgina Novell³, anastasia Motcritcaia³, Beatriz Frade Sosa⁴, Juan Camilo Sarmiento-Monroy⁵, Vicenç Torrente-Segarra⁶, Julio Ramirez⁷, Virginia Ruiz-Esquide⁸, ana Belen Azuaga³, Francisco Vilchez³, Sandra Farietta³, Patricia Corzo⁹, Juan Cañete¹⁰, José Gomez-Puerta¹¹ and Raimon Sanmartí⁸, ¹Hospital Clinic, Barcelona, Spain, ²Consorci Sanitari Alt Penedès-Garraf, Barcelona, Catalonia, Spain, ³Hospital Clinic, Barcelona, Catalonia, Spain, ⁴Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, ⁵Hospital Clínic Barcelona, Barcelona, Spain, ⁶Hospital Comarcal Alt Penedés Garraf, Vilafranca del Penedès, Spain, ⁷Clinic Barcelona Hospital Universitari, Barcelona, Catalonia, Spain, ⁸Hospital Clínic de Barcelona, Barcelona, Catalonia, Spain, ⁹Rheumatology Department, Hospital Clínic, Barcelona, Barcelona, Spain, ¹⁰Rheumatology Department, Hospital Clínic and IDIBAPS, Barcelona, Spain, Barcelona, Spain, ¹¹Rheumatology Department, Hospital Clinic, Barcelona, Spain, Barcelona, Spain
Background/Purpose: Palindromic rheumatism (PR) is characterized by intermittent episodes of arthritis or periarthritis, and it can progress to rheumatoid arthritis (RA), particularly in patients with…
Abstract Number: 1431 • ACR Convergence 2025
Radiographic Sacroiliitis in Psoriatic Arthritis: Clinical, Laboratory, and Spinal Radiographic Correlates in an Indian Cohort
SUBIN PHILIP¹, RITESH KUMAR MISHRA², RIZWANA NAUSHAD¹, Lovely Kumari³, Vishnu Koneru⁴, Aishwarya Gopal⁵, Christina Mariaselvam⁶, Chengappa Kavadichanda⁷, Ananthakrishnan Ramesh¹, Molly Thabah¹ and VIR SINGH NEGI¹, ¹JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, Puducherry, India, ²JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, Bhubaneswar, India, ³Jawaharlal Institute of Postgraduate Medical Education and Research,PUDUCHERRY, PUDUCHERRY, Puducherry, India, ⁴JIPMER, Hyderabad, Telangana, India, ⁵Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, Puducherry, India, ⁶Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, Puducherry, India, ⁷Jawaharlal Institute of Postgraduate Medical Education and Research, pondicherry, Puducherry, India
Background/Purpose: Axial involvement in psoriatic arthritis (PsA) is variable and influences treatment choices. Data on axial PsA in Indian patients, especially its clinical and radiographic…
Abstract Number: 0834 • ACR Convergence 2025
Heterogeneity in the Association of Genetic Risk for Rheumatoid Arthritis and Resultant Rheumatoid Arthritis Phenotypes
Thomas Riley¹, Austin Wheeler², Bryant England², Grant Cannon³, Brian Sauer⁴, Gary Kunkel⁵, Katherine Wysham⁶, Beth Wallace⁷, Paul Monach⁸, Andreas Reimold⁹, Gail Kerr¹⁰, Isaac Smith¹¹, John Richards¹², Iris Lee¹³, Geoffrey Thiele², Rui Xiao¹, Scott Damrauer¹⁴, Michael Levin¹⁴, Michael George¹, Ted Mikuls² and Joshua Baker¹, ¹University of Pennsylvania, Philadelphia, PA, ²University of Nebraska Medical Center, Omaha, NE, ³University of Utah and Salt Lake City VA, Salt Lake City, UT, ⁴Salt Lake City VA/University of Utah, Salt Lake City, UT, ⁵University of Utah and George E Wahlen VAMC, Salt Lake City, UT, ⁶VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, ⁷Michigan Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, ⁸VA Boston Healthcare System, Boston, MA, ⁹Dallas VA Medical Center, Dallas, TX, ¹⁰Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, ¹¹Duke University Hospital, Durham, NC, ¹²Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, ¹³Washington University in St Louis, Saint Louis, MO, ¹⁴University of Pennsylvania / Corporal Michael J. Crescenz VAMC, Philadelphia, PA
Background/Purpose: The impact of genetic risk factors on rheumatoid arthritis (RA) phenotype is incompletely understood. Comparing individual genetic variants associated with RA susceptibility to a…
Abstract Number: 0315 • ACR Convergence 2025
Cross-sectional analysis of association between erosive hand osteoarthritis and cardiovascular disease.
Avanika Mahajan¹, Caroyln Harvey², Andy Abril³ and Megan Sullivan⁴, ¹Mayo Clinic, Scottsdale, ²Mayo Clinic, Phoenix, AZ, ³Mayo Clinic Florida, Jacksonville, ⁴Mayo Clinic Arizona, Scottsdale, AZ
Background/Purpose: Erosive hand osteoarthritis (EHOA) is an inflammatory subtype of hand OA that causes subchondral bone erosion and cortical destruction, often resulting in debilitating symptoms.…
Abstract Number: 0227 • ACR Convergence 2024
Active Hand Inflammation: Differing Clinical and Ultrasound Patterns in Patients with Rheumatoid Arthritis and Psoriatic Arthritis. A Cross-Sectional and Multicenter Study
Julio Ramírez¹, Vicenç Torrente-Segarra², Andrea Cuervo³, Mireia Moreno⁴, Ana Belén Azuaga¹, Lourdes Mateo⁵, Beatriz Frade-Sosa⁶, Andrea Zacarias¹, Noemí Busquets Pérez⁷, Susana Holgado⁸, Paula Estrada-Alarcón⁹, Delia Reina¹⁰, Juan José De Agustín¹¹, Carme Moragues¹², María Bonet¹³, Sandra Farietta¹, Patricia Corzo¹, Andrés Ponce¹⁴, Virginia Ruiz Esquide¹, Lucia Alascio¹ and Juan Cañete¹⁵, and ECOCAT group, ¹Hospital Clinic Barcelona, Barcelona, Spain, ²Hospital Comarcal Alt Penedès-Garraf, Vilafranca, Spain, ³Hospital General Granollers, Granollers, Spain, ⁴Hospital Parc Taulí, Sabadell, Spain, ⁵Hospital Germans Trias i Pujol, Badalona, Spain, ⁶Hospital Clínic, Barcelona, Spain, ⁷HOSP. GENERAL DE GRANOLLERS, GRANOLLERS, Spain, ⁸Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ⁹Hospital de San Juan Despí Moisès Broggi, Barcelona, Spain, ¹⁰Hospital Moises Broggi, Barcelona, Spain, ¹¹Image and Technics Unit, Department of Rheumatology. Hospital Universitari Vall d’Hebron, Barcelona, Spain, ¹²Hospital Bellvitge, Barcelona, Spain, ¹³Hospital Alt Penedés i Garraf, Barcelona, Spain, ¹⁴Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, ¹⁵Hospital Clinic an IDIBAPS, Barcelona, Spain
Background/Purpose: The ultrasound (US) finding of proliferative synovitis (PS) in Rheumatoid Arthritis (RA), is associated with ACPA, erosions and changes in therapy [1]. However, no…
Abstract Number: 0379 • ACR Convergence 2024
Effectiveness and Safety of Baricitinib for the Treatment of Juvenile Idiopathic Arthritis Associated Uveitis or Chronic Anterior Antinuclear Antibody Positive Uveitis in Children
Athimalaipet Ramanan¹, Catherine Guly², Gabriele Simonini³, Stuart Keller⁴, Priyanka Sen⁴, Thorsten Holzkaemper⁴ and PIERRE QUARTIER⁵, ¹Bristol Royal Hosp for Children, Bristol, United Kingdom, ²University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom, ³Meyer Children’s Hospital IRCCS; University of Florence, Florence, Toscana, Italy, ⁴Eli Lilly and Company, Indianapolis, IN, ⁵Université Paris-Cite, IMAGINE Institute, Necker Children’s Hospital, Paris Cedex 15, France
Background/Purpose: Baricitinib could target multiple cytokine pathways associated with juvenile idiopathic arthritis associated uveitis (JIA-U) and antinuclear antibody (ANA)-positive uveitis, providing a novel therapeutic approach.…
Abstract Number: 0866 • ACR Convergence 2024
Cross-sectional Analysis of Erosive Hand Osteoarthritis and Fracture Risk
Avanika Mahajan¹, carolyn mead harvey², Chris Grilli³ and Megan Sullivan³, ¹Mayo Clinic - - Scottsdale, AZ, Phoenix, AZ, ²Mayo Clinic Florida, Jacksonville, FL, ³Mayo Clinic Arizona, Scottsdale, AZ
Background/Purpose: Erosive hand osteoarthritis (EHOA) is a subtype of hand OA that primarily impacts the interphalangeal joints resulting in subchondral bone erosion and cortical destruction.…
Abstract Number: 0937 • ACR Convergence 2024
A Novel Quantitative Method Reveals Bone-Structural Changes During Course of Inflammatory Arthritis
Anders Nguyen¹, David McBride², Miriam Bollmann¹, Agnieszka Lastowska³ and Mattias Svensson⁴, ¹University of Gothenburg, Göteborg, Sweden, ²Calibr-Skaggs Institute for Innovative Medicines, La Jolla, CA, ³University of Gothenburg, Goteborg, Sweden, ⁴University of Gothenburg, Gothenburg, Sweden
Background/Purpose: Rheumatoid Arthritis (RA) is a chronic inflammatory disease characterized by both localized and generalized bone loss. The inhibition of Receptor Activator of Nuclear Factor…
Abstract Number: 1346 • ACR Convergence 2024
Early Diagnosis of Rheumatoid Arthritis: Role of Joint Ultrasound Assessment
Cristina Corrales Selaya¹, Carmen Secada Gómez², Sabela Fernandez-Aguado³, Isla Morante-bolado⁴, Montserrat Santos-gomez⁵, Sara Alonso-Castro⁶, Virginia Portilla-González⁷, Ricardo Blanco-Alonso⁸, Javier Rueda Gotor⁴ and alfonso Corrales-Martínez⁹, ¹Rheumatology, Marques de Valdecilla University Hospital. IDIVAL, Santander, Cantabria, Spain, ²Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Hospital Universitario Montecelo, Pontevedra, Galicia, Spain, ⁴Hospital Sierrallana, Torrelavega, Cantabria, Spain, ⁵Hospital universitario Central de Asturias, Oviedo, Asturias, Spain, ⁶Hospital Universitario Central de Asturias., Oviedo, Asturias, Spain, ⁷Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ⁸Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain, ⁹Hospital Universitario Marques de Valdecilla, Santander, Spain
Background/Purpose: Early diagnosis of Rheumatoid Arthritis (RA) is essential to establish treatment to improve long-term disease outcomes. Musculoskeletal ultrasound (US) is able to detect subclinical…
Abstract Number: 1429 • ACR Convergence 2024
Association of Bone Erosion and Microarchitecture with Disease Activity and Damage in Sjögren’s Disease
Andre Franco¹, Igor Murai², Thomas Yang², Valeria Caparbo³, Virginia Bonoldi², Diogo Domiciano¹, Lissiane Guedes², Sandra Pasoto¹, Camille Figueiredo³ and Rosa M R Pereira³, ¹Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, ²Hospital das Clinicas HCFMUSP, Faculdade de Medicina da USP, São Paulo, SP, Brazil, ³Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., São Paulo, SP, Brazil
Background/Purpose: Sjögren's disease (SjD) is a chronic multisystem autoimmune condition characterized by sicca syndrome and inflammatory arthralgia, more common in women. Bone involvement can result…
Abstract Number: 1456 • ACR Convergence 2024
Real-World Treat-to-Target Strategy in Psoriatic Arthritis: Baseline Characteristics from the MONITOR-PsA Cohort
Lija James¹, Elnaz Saeedi², Jean-Guillaume Letarouilly¹, Nicola Gullick³, Anne Francis², Deepak Jadon⁴, William Tillett⁵, Yvonne Sinomati², Laura Tucker¹, Nadia Mian², Ines Rombach², Ioana Marian², Maria Sofia Massa² and Laura Coates⁶, ¹Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ²Oxford Clinical Trials Research Unit, University of Oxford, Oxford, United Kingdom, ³Rheumatology Department, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, Coventry, United Kingdom, ⁴Cambridge University, Cambridge, United Kingdom, ⁵Royal National Hospital of Rheumatic Diseases; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom, ⁶University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom
Background/Purpose: Psoriatic arthritis (PsA) is a chronic musculoskeletal disease, which can lead to progressive joint pain, joint destruction, and loss of function. Evidence suggests that…
Abstract Number: 2224 • ACR Convergence 2024
Age of Onset of Rheumatoid Arthritis and Radiographic Changes
Masaru Shimizu¹, Misti Paudel², Nancy Shadick³, Michael Weinblatt⁴ and Daniel Solomon⁵, ¹University of Tsukuba, Yokohama, Kanagawa, Japan, ²Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, ⁵Brigham and Women's Hospital, Newton, MA

Background/Purpose: Epidemiological studies have shown that the age of onset for rheumatoid arthritis (RA) is increasing. However, associations between age of onset and joint erosion…
Abstract Number: 2549 • ACR Convergence 2023
Effect of Ixekizumab Treatment on MRI Structural Lesions in the Sacroiliac Joints of Patients with Radiographic Axial Spondyloarthritis; A Post-hoc Analysis of a Placebo and Active Controlled RCT
Walter P. Maksymowych¹, Robert Lambert², Eswar Krishnan³, Baojin Zhu³, Rebecca Bolce³ and Mikkel Østergaard⁴, ¹University of Alberta, Edmonton, AB, Canada, ²Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ³Eli Lilly and Company, Indianapolis, IN, ⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark
Background/Purpose: The effect of Ixekizumab (IXE) on structural lesions in the sacroiliac joints (SIJ) of patients (pts) with radiographic Axial Spondylarthritis (r-axSpA) assessed by magnetic…
Abstract Number: 0745 • ACR Convergence 2023
Artificial Intelligence Models for Computer-Assisted Joint Detection and Sharp-van Der Heijde Score Prediction in Hand Radiographs from Patients with Rheumatoid Arthritis
Carol Hitchon¹, Saqib Al Islam¹, Daryl LX Fung¹, Qian Liu¹, Leann Lac¹, Susan Bartlett², Louis Bessette³, Gilles Boire⁴, Vivian Bykerk⁵, Glen Hazlewood⁶, Edward Keystone⁷, Janet Pope⁸, Orit Schieir⁹, Carter Thorne¹⁰, Diane Tin¹¹, Marie-France Valois¹², Désirée van der Heijde¹³, Canadian Early Arthritis Cohort (CATCH) Investigators¹⁴, Liam O'Neil¹ and Pingzhao Hu¹⁵, ¹University of Manitoba, Winnipeg, MB, Canada, ²McGill University, Montreal, QC, Canada, ³Centre de l'Ostéoporose et de Rhumatologie de Québec, Quebec City, QC, Canada, ⁴Université de Sherbrooke, Sherbrooke, QC, Canada, ⁵Hospital for Special Surgery, New York, NY, ⁶University of Calgary, Calgary, AB, Canada, ⁷Keystone Consulting Enterprises Inc., Toronto, ON, Canada, ⁸University of Western Ontario, London, ON, Canada, ⁹McGill University, Montréal, QC, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹The Arthritis Program Research Group, Newmarket, ON, Canada, ¹²McGill University, Pointe-Claire, QC, Canada, ¹³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ¹⁴CATCH, Winnipeg, MB, Canada, ¹⁵Western University, London, ON, Canada
Background/Purpose: Radiographs are used to detect and monitor joint damage due to rheumatoid arthritis (RA).Scoring methods such as the Sharp van der Heijde tool (SVH)…

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