Abstracts tagged "Epidemiology"

Abstract Number: 0745 • ACR Convergence 2025
Prevalence and Clinical Significance of Low ESR and CRP in Giant Cell Arteritis: A Population Based Study
Eugenio de Miguel, Natalia López-Juanes, Maria-Eugenia Miranda-Carus, Carlota Ureta, Chamaida Plasencia-Rodríguez and Irene Monjo Henry, Hospital Universitario La Paz, Madrid, Spain
Background/Purpose: Traditionally, elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) had been considered a hallmark of GCA and both are included in the 2022…
Abstract Number: 0324 • ACR Convergence 2025
Bile Acids Metabolism in Symptomatic Hand Osteoarthritis: Data from the Xiangya Osteoarthritis Study and Genetics of OA Consortium
Jiatian Li¹, Jing Ye¹, Tuo Yang¹, david Hunter², Weiya Zhang³, Michael Doherty³, Yuqing Zhang⁴, Zidan Yang¹, Hui Li¹, Yilun Wang¹, Dongxing Xie¹, Ziying Wu⁵, Wei Li¹, Zeqin Wen¹, Changjun Li¹, Chao Zeng¹, Guanghua Lei¹ and Jie Wei¹, ¹Xiangya Hospital, Central South University, Changsha, Hunan, China (People's Republic), ²Sydney Musculoskeletal Health, University of Sydney, St Leonards, New South Wales, Australia, ³School of Medicine, University of Nottingham, Nottingham, United Kingdom, ⁴Massachusetts General Hospital, Quincy, MA, ⁵Xiangya Hospital, Central South University, Chang Sha, China (People's Republic)
Background/Purpose: Although gut microbiome dysbiosis has been implicated in symptomatic hand OA (SHOA), the potential contribution of bile acids (BAs), key metabolites in host-microbiota interactions,…
Abstract Number: 0037 • ACR Convergence 2025
A Proteomic Signature Containing TNF Receptor Superfamily Member 10A (TNFRSF10A) and Growth/Differentiation Factor 15 (GDF-15) Improves Prediction of All-Cause Mortality Among Individuals with Gout, Beyond Atherosclerotic Cardiovascular and Other Clinical Risk Factors
Natalie McCormick¹, Sharan Rai², Chio Yokose³, Tony Merriman⁴, Robert Terkeltaub⁵ and Hyon K. Choi⁶, ¹Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital/Harvard Medical School, Boston, MA, ³Massachusetts General Hospital, Waltham, MA, ⁴University of Alabama at Birmingham, Homewood, AL, ⁵Retired, San Diego, CA, ⁶MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA
Background/Purpose: Gout affects >12 million US adults and is associated with premature all-cause and cardiovascular (CV) mortality which has failed to improve over recent decades,…
Abstract Number: 2545 • ACR Convergence 2025
Prevalence, Clinical Correlations and Outcomes of Cryoglobulinemic Vasculitis: a Retrospective Monocentric Study (2013–2023)
Valeria Manfrè¹, elena treppo², Maria Pillon³, Maria De Martino⁴, Cinzia Fabro⁵, Miriam Isola⁴, Martina Fabris⁶, Francesco Curcio⁶ and Luca Quartuccio¹, ¹Division of Rheumatology, Department of Medicine (DMED), Academic Hospital "Santa Maria della Misericordia", ASUFC, University of Udine, Udine, Italy, Udine, Italy, ²Division of Rheumatology, Department of Medicine, University of Udine, Udine, Italy, ³Division of Rheumatology, Department of Medicine, University of Udine, Udine, Italy, Udine, Italy, ⁴Institute of Statistics, Department of Medicine, University of Udine, Udine, Italy., Udine, Italy, ⁵Division of Rheumatology, Department of Medicine, University of Udine, Udine, Italy., Udine, Italy, ⁶Institute of Clinical Pathology, Department of Medicine, University of Udine, Udine, Italy., Udine, Italy
Background/Purpose: Cryoglobulinemic vasculitis (CryoVas) is a rare immune-complex-mediated disorder, often associated with hepatitis C virus (HCV) infection, autoimmune diseases (ADs), or other etiologies. Despite its…
Abstract Number: 1925 • ACR Convergence 2025
Associations between Representation and Quality in Clinical Trials for Systemic Lupus Erythematosus
Joshua Skydel¹, Anna Leland², Reshma Ramachandran³, Fotios Koumpouras³ and Joshua Wallach², ¹Yale-New Haven Hospital, New Haven, CT, ²Rollins School of Public Health, Atlanta, GA, ³Yale School of Medicine, New Haven, CT
Background/Purpose: Drug development in SLE is informed by US Food and Drug Administration recommendations for study design, enrollment, and efficacy endpoints. However, persistent challenges to…
Abstract Number: 1887 • ACR Convergence 2025
Incidence, Prevalence and Mortality of Systemic Lupus Erythematosus – A 20-year territory-wide analysis of electronic health records in Hong Kong
Danting zhang¹, jiaxin S. Wu¹ and Desmond Yat-Hin Yap², ¹The University of Hong Kong, Hong Kong, Hong Kong, ²Department of Medicine, The University of Hong Kong, Hong Kong SAR, Hong Kong
Background/Purpose: Advancements in immunosuppressive treatments and general medical care in the past two decades have influenced the disease burden and outcomes of patients with systemic…
Abstract Number: 1584 • ACR Convergence 2025
Evaluation of Adverse Childhood Experiences in Systemic Sclerosis: Prevalence and Patient Characteristics
Samuel Good¹, Nahal Ghanoongooi¹, Ju Young Lee², Arissa Young³ and Elizabeth Volkmann¹, ¹David Geffen School of Medicine at University of California, Los Angeles, Department of Medicine, Division of Rheumatology, Los Angeles, CA, ²David Geffen School of Medicine at University of California, Los Angeles, Department of Medicine, Los Angeles, CA, ³UCLA, Los Angeles, CA
Background/Purpose: There is growing evidence that trauma, and in particular adverse childhood experiences (ACEs), play a role in the pathogenesis and exacerbation of systemic autoimmune…
Abstract Number: 1312 • ACR Convergence 2025
Evolution of patients with active rheumatoid arthritis: analysis of disease activity trajectories in a tertiary‑care rheumatology department
Elodie Portier¹, Olivier Fogel², Terkia Medkour³, Sophie Hecquet³ and Jérôme AVOUAC³, ¹Rheumatology department, Bicetre hospital, Le Kremlin Bicetre, France, ²AP-HP, Paris, France, ³Rheumatology department, Cochin hospital, Paris, France
Background/Purpose: The objective of this study was to identify clusters of patients with rheumatoid arthritis (RA) in clinical practice, according to evolution of disease activity…
Abstract Number: 1018 • ACR Convergence 2025
Factors Associated with Mortality in Systemic Lupus Erythematosus under a Universal Healthcare System: Results from the CAPTURED Study, a Population-Based Cohort in Catalonia, Spain
José Gomez-Puerta¹, Cristian Tebe², Maria Grau³, Beatriz Frade Sosa⁴, Juan Camilo Sarmiento-Monroy⁵, Cristina Carbonell-Abella⁶, Daniel Martinez-Laguna⁷, Patricia Corzo⁸, Raimon Sanmartí⁹ and J. Antonio Aviña-Zubieta¹⁰, ¹Rheumatology Department, Hospital Clinic, Barcelona, Spain, Barcelona, Spain, ²Instituto de Investigación Germans Trias i Pujol, Badalona, Spain, ³University of Barcelona, Barcelona, Spain, ⁴Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, ⁵Hospital Clínic Barcelona, Barcelona, Spain, ⁶Medicina Familiar y Comunitaria, Centro de Salud Vía Roma, Barcelona, Spain, ⁷Grup de recerca en malalties prevalents de l'Aparell locomotor en Atenció Primaria (GREMPAL), ICS, Barcelona, Spain, ⁸Rheumatology Department, Hospital Clínic, Barcelona, Barcelona, Spain, ⁹Hospital Clínic de Barcelona, Barcelona, Catalonia, Spain, ¹⁰University of British Columbia/Arthritis Research Canada, Vancouver, BC, Canada
Background/Purpose: The differences in lupus-related mortality reported in population studies are partly explained by racial disparities and access to healthcare. However, population-based data from universal…
Abstract Number: 0735 • ACR Convergence 2025
A Real-World Study from the Greater Paris Clinical Data Warehouse
Aïcha Kante¹, Olivier Hassanaly², Geoffroy Peyrac³, David Saadoun⁴, Cacoub Patrice⁴, Alexis REGENT⁵, Benjamin Terrier⁶, Luc Mouthon⁷, Arsène Mekinian⁸, Karim Sacré⁹, Jean-François Alexandra¹⁰, Sébastien Abad¹¹, Robin Dhote¹¹, Cécile goujard¹², Damien Sène¹³, Stéphane Mouly¹⁴, Baptiste Hervier¹⁵, Olivier Bory¹⁶, Elisabeth Aslangul¹⁶, Isabelle Mahé¹⁶, Anne Couvelard¹⁷, Yann Nguyen¹⁸, Agnès Lefort¹⁸, Sophie georgin-Lavialle¹⁹, Olivier Steichen¹⁹, Viet-Thi Tran²⁰ and Cloé Comarmond¹, ¹Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, INSERM U⁹⁴², Paris, France, ²Unité de recherche clinique, AP-HP, Hôpital Saint Louis, F⁷⁵⁰¹⁰, Paris, France, Paris, France, ³Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, AP-HP, Paris, France, ⁴Department of Internal Medicine and Clinical Immunology, Sorbonne Universités, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Centre national de références Maladies Autoimmunes et systémiques rares, Centre national de références Maladies Autoinflammatoires rares et Amylose inflammatoire (CEREMAIA), INSERM, UMR S⁹⁵⁹, Immunology-Immunopathology-Immunotherapy (I³), Paris, France, Paris, France, ⁵Hopital Cochin, Paris, France, ⁶Cochin Hospital, Paris, France, ⁷Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Cochin University Hospital, Université Paris Cité, AP-HP, Paris, France, ⁸Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i³), Saint-Antoine University Hospital, ⁷⁵⁰¹² Paris, France, Paris, France, ⁹Department of Internal Medicine, Bichat University Hospital, Université Paris Cité, AP-HP, Paris, France, Paris, France, ¹⁰Internal Medicine, Hôpital Bichat, APHP, Paris, France, ¹¹Service de Médecine Interne, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris (AP-HP); Université Paris ¹³, Sorbonne Paris Cité, Bobigny, France, Bobigny, France, ¹²Université Paris Saclay, Department of Internal Medicine and Clinical Immunology, Bicêtre Hospital, APHP, UMR¹¹⁸⁴ Inserm, CEA, Le Kremlin Bicêtre, France, Kremlin Bicêtre, France, ¹³Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, Paris, Ile-de-France, France, ¹⁴Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, Paris, France, ¹⁵Internal Medicine Department, Hôpital Saint-Louis, AP-HP, Université Paris Cité, Paris, France., Paris, France, ¹⁶Department of Internal Medicine, Louis-Mourier Hospital, AP-HP, Colombes, France, Colombes, France, ¹⁷Pathology Department, Bichat and Beaujon Hospitals, AP-HP, FHU MOSAIC, Université Paris Cité, Paris, France, Paris, France, ¹⁸Department of Internal Medicine, Beaujon Hospital, AP-HP Nord, Université Paris Cité, Clichy, France, Clichy, France, ¹⁹Sorbonne university, Tenon hospital, DMU³ID, CEREMAIA, ERN RITA, Paris, France, ²⁰Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAe, Centre for Research in Epidemiology and Statistics (CRESS), Paris; and Centre d'Epidémiologie Clinique, Hôpital Hôtel-Dieu, AP-HP, Paris, France, Paris, France
Background/Purpose: Giant cell arteritis (GCA) relapses are frequent and often require therapeutic intensification in the form of glucocorticoids (GC) increase. GCA management has significantly evolved…
Abstract Number: 0322 • ACR Convergence 2025
Metabolites Reflective of the Gut Microbiome Relate to Future Incident Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Jeffrey Driban¹, Shike Xu², Timothy McAlindon³, John Haran⁴, Julieann Patarini⁴ and Bing Lu⁵, ¹University of Massachusetts Chan Medical School, Marlborough, NH, ²University of Connecticut Health Center, Farmington, CT, ³UMass Chan School of Medicine, Arlington, MA, ⁴UMass Chan Medical School, Worcester, MA, ⁵UConn Health Center, Newton, MA

Background/Purpose: Numerous cross-sectional and animal studies have linked an altered gut microbiome to osteoarthritis (OA). Human studies are needed to explore the association between the…
Abstract Number: 1507 • ACR Convergence 2025
Temporal Trends in the Incidence of Systemic Lupus Erythematosus (SLE) in the United States (US): Holding Steady?
Sasha Bernatsky¹, Sharon Dowell², Brittany Banbury³, Jeffrey Curtis⁴, Grace Wright⁵, Emily Holladay⁶, Amy Mudano⁷, Cristiano Moura⁸ and Gail Kerr⁹, ¹Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ²NEA Baptist Memorial Hospital, Jonesboro, AR, ³Mount Sinai Beth Israel, Brooklyn, NY, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Grace C Wright MD PC, New York, NY, ⁶University of Alabama at Birmingham, Edmond, OK, ⁷Foundation for Advancing Science, Technology, Education and Research (FASTER), Birmingham, AL, ⁸Research Institute of the McGill University Health Center, Montréal, Canada, ⁹Washington DC VAMC/Georgetown and Howard Universities, Washington, DC
Background/Purpose: Since SLE is associated with significant morbidity and healthcare burden, estimates of SLE incidence are needed to inform research and public health initiatives, including…
Abstract Number: 2685 • ACR Convergence 2025
Assessing for Racial/Ethnic Variability in U.S.-FRAXTM Performance Among Older Adult Women with Rheumatoid Arthritis in the United States
Rachel Elam¹, Jing Li², Angel Paul³, Emma Kersey⁴, gabriela Schmajuk⁵, William Leslie⁶ and Laura Carbone¹, ¹Augusta University, Augusta, GA, ²University of California, San Francisco, San Francisco, CA, ³University of California San Francisco, Berkeley, CA, ⁴University of California San Francisco, San Francisco, CA, ⁵University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA, ⁶University of Manitoba, Winnipeg, MB, Canada
Background/Purpose: Women with rheumatoid arthritis (RA) have 1.5- and 2-fold higher risk of major osteoporotic fracture (MOF: first of distal forearm, hip, humerus, or clinical…
Abstract Number: 2336 • ACR Convergence 2025
Early Axial Spondyloarthritis in Latin America: Prevalence and Regional Differences from the “ESPALDA” Multinational Registry
Wilson bautista molano¹, Guillermo Guaracha², Fernando Sommerfleck³, Rodrigo García Salinas⁴, Julio Cesar Casasola Vargas⁵, John Londono⁶, Daniel Fernandez⁷, Diego Vila⁸, Lorena Brance⁹, Jossiel Then¹⁰, francisco Zeballos¹¹, Lysseth Macias¹², Marilu mestanza¹³, Daisy Sanchez¹⁴, lYN chincháy¹⁵, Patricia Melgarejo¹⁶, Angel Castillo¹⁷, Gimena Gomez¹⁸, Leandro ferreryra¹⁹, Dora candia²⁰, Gustavo medina²¹, Maria Erguez²², Einer Sanchez⁴ and Daniel Palleiro²³, ¹University Hospital Fundacion Santa Fe de Bogota, Bogota, Colombia, ²Instituto Nacional de Ciencias Médicas y Nutrición 'Salvador Zubirán', Ciudad de México, Mexico, Mexico, ³Sanatorio Julio Mendez, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁴Hospital Italiano La Plata, La Plata, Argentina, ⁵CAVJ^7111038Q⁹, MEXICO CITY, Mexico, ⁶Hospital Militar Central , Universidad de La Sabana, Colombia, Bogota, Colombia, ⁷Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia; Departamento de Medicina Interna, Unidad de Reumatología, Hospital Universitario San Ignacio, Bogotá, Colombia, BOGOTA, Colombia, ⁸Hospital Virgen del Carmen, Buenos Aires, Argentina, Buenos Aires, Argentina, ⁹School of Medicine, Rosario National University, Argentina, Rosario, Argentina, ¹⁰HOMS, Santiago, Dominican Republic, ¹¹Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, ¹²Consultorio sse, Hospital Metropolitano, Ecuador, Quito, Ecuador, ¹³Hospital Metropolitano, Ecuador, Quito, Ecuador, ¹⁴Sociedad Ecuatoriana de Reumatología, GUAYAS - GUAYAQUIL, Ecuador, ¹⁵Hospital Guillermo Kaelin de La Fuente, Perú, Lima, Peru, ¹⁶Instituto de Previsión Social, Villarrica, Paraguay, ¹⁷Centro médico de las Americas, Merida, Mexico, ¹⁸Sanatorio Guemes, Buenos Aires, Argentina, ¹⁹HIBA, CABA, Ciudad Autonoma de Buenos Aires, Argentina, ²⁰Hospital Regional Primero de Octubre ISSTE, Fuerzas Armadas, México, Durango, Mexico, ²¹Clinical Hospital Buenos Aires University, Quilmes, Argentina, ²²SAR, Guayaquil, Ecuador, ²³INRU, Montevideo, Uruguay
Background/Purpose: The ESPALDA registry, developed by PANLAR, collects data from Latin America to better understand the clinical and epidemiological characteristics of patients with axial spondyloarthritis…
Abstract Number: 1911 • ACR Convergence 2025
Characterizing Psoriasis Patients at Risk for Transition to Psoriatic Arthritis: Early Insights from the STOP PsA At-Risk Cohort
Victoria Konzett¹, Eva Manger², Simon Reider², Johannes Griss³, Constanze Jonak³, Kastriot Kastrati⁴, Peter Mandl⁴, Gudrun Ratzinger⁵, Christina Duftner², Thomas Karonitsch⁴ and Daniel Aletaha⁶, ¹Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Internal Medicine, Clinical Division of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria, ³Department of Dermatology, Medical University of Vienna, Austria, Vienna, Austria, ⁴Department of Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria, ⁵Department of Dermatology, Venereology and Allergology, Medical University of Innsbruck, Austria, Innsbruck, Austria, ⁶Medical University Vienna, Wien, Austria
Background/Purpose: Psoriatic arthritis (PsA) develops predominantly in patients with psoriasis (Pso). Although key drivers and predictors of disease progression have been identified in recent years,…

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