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Abstracts tagged "Environmental factors"

  • Abstract Number: 839 • 2015 ACR/ARHP Annual Meeting

    Occupational Exposures in Patients with Systemic Sclerosis Associated with Increased Frequency of Interstitial Lung Disease and Primary Pulmonary Hypertension

    Brandi E. Stevens1,2, Mary Lucas3, Thomas A. Medsger Jr.4 and Robyn T. Domsic5, 1Division of Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Medicine-Rheumatology, University of Pittsburgh, Pittsburgh, PA, 3Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4Department of Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, 5Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Systemic sclerosis (SSc) has been linked with environmental and occupational exposures. Silica and solvent exposure have the strongest known correlation with SSc. Other agents,…
  • Abstract Number: 1210 • 2015 ACR/ARHP Annual Meeting

    Genetic, Environmental, and Serologic Risk Factors for Inflammatory Joint Signs Among First-Degree Relatives without Rheumatoid Arthritis in a Prospective Cohort

    Jeffrey A. Sparks1, Shun-Chiao Chang2, Kevin D. Deane3, Ryan W. Gan4, Kristen Demoruelle3, Marie L. Feser3, LauraKay Moss3, Jane H. Buckner5, Richard M. Keating6, Karen H. Costenbader7, Peter K. Gregersen8, Michael H. Weisman9, Ted R. Mikuls10, James R. O'Dell10, V. Michael Holers3, Jill M. Norris4 and Elizabeth W. Karlson2, 1Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 4Epidemiology, Colorado School of Public Health, Aurora, CO, 5Benaroya Research Institute at Virginia Mason, Seattle, WA, 6Division of Rheumatology, Scripps Health, La Jolla, CA, 7Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 8Feinstein Insititute for Medical Research, Manhasset, NY, 9Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 10Veteran Affairs Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Family history of RA in a first-degree relative increases RA risk 4-fold. Determining risk factors for inflammatory joint signs (IJS) in this high risk…
  • Abstract Number: 2058 • 2014 ACR/ARHP Annual Meeting

    The Impact of Environmental Stress on Pain in Fibromyalgia Patients

    Robert S. Katz1, Ben J Small2 and Susan Shott3, 1Rush Medical College, Chicago, IL, 2MacNeal Hospital, Berwyn, IL, 3Rush University Medical Center, Chicago, IL

    Background/Purpose:  Many fibromyalgia syndrome (FMS) report that their illness is significantly affected by environmental stress. We compared FMS and RA patients with respect to the…
  • Abstract Number: 2008 • 2014 ACR/ARHP Annual Meeting

    Personalized Risk Education for Rheumatoid Arthritis Improves Self-Perceived Risk Accuracy and Risk Factor Knowledge in First-Degree Relatives

    Jeffrey A. Sparks1, Maura D. Iversen1,2,3, Rachel Miller Kroouze1,4, Nellie A. Triedman1, Taysir G. Mahmoud1, Sarah S. Kalia4, Michael L. Atkinson5, Robert C. Green4 and Elizabeth W. Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Department of Physical Therapy, Movement & Rehabilitation Sciences, Northeastern University, Boston, MA, 3Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden, 4Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 5Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose Having a first-degree relative (FDR) with RA increases personal RA risk by four-fold. Other RA risk factors include demographics, genetics, auto-antibodies, and behaviors. We…
  • Abstract Number: 2017 • 2014 ACR/ARHP Annual Meeting

    Fish Consumption and Risk of Rheumatoid Arthritis Among Women in Large Prospective Cohorts

    Jeffrey A. Sparks1, Shun-Chiao Chang2, Bing Lu1, Susan Malspeis1, Karen H. Costenbader1 and Elizabeth W. Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose Prior studies have suggested a protective effect of fish intake on RA. However, these studies were limited by potential recall bias, short follow-up, and…
  • Abstract Number: 2015 • 2014 ACR/ARHP Annual Meeting

    Fine Particulate Air Pollution and Systemic Autoimmune Rheumatic Disease in Two Canadian Provinces

    Sasha Bernatsky1, Audrey Smargiassi2, Cheryl Barnabe3, Lawrence W. Svenson4, Allan Brand5, Marie Hudson6, Steven M. Edworthy7, Ann E. Clarke3, Paul R. Fortin8, Patrick Belisle9 and Lawrence Joseph10, 1Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, 2Département de santé environnementale et santé au travail, Université de Montréal, Montréal, QC, Canada, 3Division of Rheumatology, University of Calgary, Calgary, AB, Canada, 4Community Health Sciences, University of Calgary, Calgary, AB, Canada, 5Institut national de santé publique du Québec, Montreal, QC, Canada, 6Rheumatology, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, 7The University of Calgary, Calgary, AB, Canada, 8Rheumatology, Laval University, Division of Rheumatology, Centre de Recherche du CHU de Québec and Department of Medicine, Quebec City, QC, Canada, 9Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 10McGill University, Montreal, QC, Canada

    Background/Purpose: To estimate the degree to which fine particulate (PM2.5) air pollution is associated with systemic autoimmune rheumatic diseases (SARDs). Methods: We used population-based administrative…
  • Abstract Number: 319 • 2014 ACR/ARHP Annual Meeting

    Systemic Juvenile Idiopathic Arthritis and Exposure to Fine Particulate Air Pollution

    Andrew S. Zeft1, Sampath Prahalad2, Rayfel Schneider3, Alexei Grom4, Fatma Dedeoglu5, Pamela F. Weiss6, Carter Mix7 and C. Arden Pope8, 1Pediatrics, Rheumatology, The Cleveland Clinic, Cleveland, OH, 2Emory University, Atlanta, GA, 3Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 4Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5on behalf of CARRAnet Investigators, Palo Alto, CA, 6Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, 7Brigham Young University, Provo, UT, 8Economics, Brigham Young University, Provo, UT

    Background/Purpose: Environmental factors are understood to play a pathogenic role in the etiology of Systemic Onset Juvenile Idiopathic Arthritis (SJIA). Fine particulate matter (aerodynamic diameter…
  • Abstract Number: 59 • 2014 ACR/ARHP Annual Meeting

    Assessing Dietary Habits in a Large Cohort of Rheumatoid Arthritis and Psoriatic Arthritis Patients: Results of the Spanish Imid Consortium

    Maria López Lasanta1, Jesús Tornero2, Juan D. Cañete3, Antonio Fernandez Nebro4, Francisco Blanco5, Jesus Rodriguez6, Isidoro González-Alvaro7, Jordi Gratacós8, Joan Maymo9, Rubén Queiro10, Mercedes Alperi-López11, Carlos Montilla-Morales12, Benjamin Fernandez Gutierrez13, Juan Carlos Torre-Alonso14, Alejandro Olive15, Jose Javier Perez Venegas16, Hector Corominas17, Alba Erra18, Santiago Muñoz19, Carlos M. Gonzalez20, Daniel Roig21, Gabriela Avila1, Arnald Alonso1, Toni Julia1, Raül Tortosa1, Andrés Garcia Montero22 and Sara Marsal1, 1Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, 2Hospital Universitario Guadalajara, Guadalajara, Spain, 3Arthritis Unit. Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, 4Rheumatology, Hospital Regional Carlos Haya, Biomedical Research Institute of Malaga (IBIMA), Malaga, Spain, 5Complejo Hospitalario Juan Canalejo, A Coruña, Spain, 6Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, 7Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 8Hospital Parc Taulí, Sabadell, Spain, 9Rheumatology, Hospital del Mar, Barcelona, Spain, 10Rheumatology Department. Hospital Universitario Central de Asturias, Oviedo, Spain, 11Rheumatology Department, Hospital Universitario Central de Asturias, Oviedo, Spain, 12H. de Salamanca, Salamanca, Spain, 13Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 14Rheumatology Department, H. Monte Naranco, Oviedo, Spain, 15Rheumatology Service, Germans Trias Pujol Hospital, Barcelona, Spain, 16Rheumatology Department, Hospital del SAS Jerez de la Frontera, Cadiz, Spain, 17Rheumatology, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain, 18Rheumatology Department, Hospital Sant Rafael, Barcelona, Spain, 19Rheumatology Department, Hospital Infanta Sofia, Madrid, Spain, 20Rheumatology Department, Gregorio Marañon Hospital, Madrid, Spain, 21Rheumatology Service, Hospital Moisès Broggi,, Barcelona, Spain, 22Banco Nacional de ADN, Salamanca, Spain

    Background/Purpose: Rheumatoid arthritis (RA) and Psoriatic arthritis (PsA) are complex diseases of unknown etiology and its pathogenesis results from the combination of genetic susceptibility and…
  • Abstract Number: 2397 • 2013 ACR/ARHP Annual Meeting

    To Which Extent May The Familial Risk Of Rheumatoid Arthritis Be Explained By Established Risk Factors?

    Xia Jiang1, Thomas Frisell2, Johan Askling3, Lars Klareskog4, Lars Alfredsson1 and Henrik Källberg1, 1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 2Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, 3Karolinska Institutet, Stockholm, Sweden, 4Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Rheumatoid arthritis (RA) is a complex inflammatory disease known to aggregate within families, implicating the crucial role of shared genetic and/or environmental factors in…
  • Abstract Number: 2271 • 2013 ACR/ARHP Annual Meeting

    Dietary Sodium Increases The Risk For Rheumatoid Arthritis Among Smokers – Results From a Nested Case-Control Study

    Björn Sundström1, Ingegerd Johansson2 and Solbritt Rantapää Dahlqvist3, 1Department of Public Health & Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, 2Department of Odontology, Cariology, Umeå Universitet, Umeå, Sweden, 3Department of Public Health and Clinical Medicine/Rheumatology, Umeå University Hospital, Umeå, Sweden

    Background/Purpose: Recent studies using animal models and human cells ex vivo have indicated that sodium chloride may affect the immune system by the inducting of pathogenic Th17…
  • Abstract Number: 2000 • 2013 ACR/ARHP Annual Meeting

    Changes In The Prevalence Of Gout In The United States General Population Between 1960 and 2010: The National Health and Nutrition Examination Surveys

    Eswar Krishnan and Linjun Chen, Medicine, Stanford University, Palo Alto, CA

    Background/Purpose: Despite the widely shared impression that the prevalence of gouty arthritis (gout) has increased over time in the US few population data are available.…
  • Abstract Number: 1773 • 2013 ACR/ARHP Annual Meeting

    The Contribution Of Environmental Factors To Familial Risk Of Rheumatoid Arthritis By Serologic Phenotypes Among Women In a Longitudinal Cohort Study

    Jeffrey A. Sparks1, Chia-Yen Chen2, Linda T. Hiraki3, Susan Malspeis4, Karen H. Costenbader4 and Elizabeth W. Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Epidemiology, Harvard School of Public Health, Boston, MA, 3Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, 4Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Familial risk of RA is composed of shared genetic and environmental factors. Previous studies exploring familial risk of RA have not incorporated environmental factors…
  • Abstract Number: 2657 • 2013 ACR/ARHP Annual Meeting

    Interactions Between Cigarette Smoking, Body Mass Index and Inflammatory Cytokine Levels In Determining The Risk Of Developing Rheumatoid Arthritis

    Elizabeth V. Arkema1, Susan Malspeis2, Bing Lu3, Linda T. Hiraki4, Elizabeth W. Karlson2 and Karen H. Costenbader2, 1Epidemiology, Harvard School of Public Health, Boston, MA, 2Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Rheumatology, Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA

    Background/Purpose:  Smoking and high body mass index (BMI) are risk factors for RA. Both are associated with increased systemic inflammation, with elevated C-reactive protein, interleukin…
  • Abstract Number: 2421 • 2013 ACR/ARHP Annual Meeting

    Association Between Physical Work Load and Rheumatoid Arthritis, Results From The EIRA Case Control Study

    Annmarie Wesley1, Henrik Källberg2, Camilla Bengtsson2, Eva Skillgate1, Johan Rönnelid3, Mohammed Mullazehi4, Lars Klareskog5, Lars Alfredsson2, Saedis Saevarsdottir6 and Sara Wedren7,8, 1Institute of Enviornmental Medicine, Karolinska Insitutet, Stockholm, Sweden, 2Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 3Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, 4Uppsala University, Uppsala, Sweden, 5Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 6Rheumatology Unit, Dept. of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 7Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 8Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: The association between occupation and RA has previously been investigated where occupations associated with a physical work load (quarry workers, construction workers, assistant nurses,…
  • Abstract Number: 2692 • 2012 ACR/ARHP Annual Meeting

    Diet and Other Lifestyle Related Factors and the Risk of Developing Rheumatoid Arthritis

    Björn Sundström1, Ingegerd Johansson2 and Solbritt Rantapää Dahlqvist3, 1Department of Public Health & Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, 2Department of Odontology, Cariology, Umeå Universitet, Umeå, Sweden, 3Department of Public Health and Clinical Medicine/Rheumatology, Umeå University Hospital, Umeå, Sweden

    Background/Purpose: There is a growing interest in the role of lifestyle in developing chronic diseases, such as rheumatoid arthritis (RA). Our aim was to investigate…
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