Abstracts tagged "Environmental factors"

Abstract Number: 319 • 2014 ACR/ARHP Annual Meeting
Systemic Juvenile Idiopathic Arthritis and Exposure to Fine Particulate Air Pollution
Andrew S. Zeft¹, Sampath Prahalad², Rayfel Schneider³, Alexei Grom⁴, Fatma Dedeoglu⁵, Pamela F. Weiss⁶, Carter Mix⁷ and C. Arden Pope⁸, ¹Pediatrics, Rheumatology, The Cleveland Clinic, Cleveland, OH, ²Emory University, Atlanta, GA, ³Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵on behalf of CARRAnet Investigators, Palo Alto, CA, ⁶Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, ⁷Brigham Young University, Provo, UT, ⁸Economics, Brigham Young University, Provo, UT
Background/Purpose: Environmental factors are understood to play a pathogenic role in the etiology of Systemic Onset Juvenile Idiopathic Arthritis (SJIA). Fine particulate matter (aerodynamic diameter…
Abstract Number: 59 • 2014 ACR/ARHP Annual Meeting
Assessing Dietary Habits in a Large Cohort of Rheumatoid Arthritis and Psoriatic Arthritis Patients: Results of the Spanish Imid Consortium
Maria López Lasanta¹, Jesús Tornero², Juan D. Cañete³, Antonio Fernandez Nebro⁴, Francisco Blanco⁵, Jesus Rodriguez⁶, Isidoro González-Alvaro⁷, Jordi Gratacós⁸, Joan Maymo⁹, Rubén Queiro¹⁰, Mercedes Alperi-López¹¹, Carlos Montilla-Morales¹², Benjamin Fernandez Gutierrez¹³, Juan Carlos Torre-Alonso¹⁴, Alejandro Olive¹⁵, Jose Javier Perez Venegas¹⁶, Hector Corominas¹⁷, Alba Erra¹⁸, Santiago Muñoz¹⁹, Carlos M. Gonzalez²⁰, Daniel Roig²¹, Gabriela Avila¹, Arnald Alonso¹, Toni Julia¹, Raül Tortosa¹, Andrés Garcia Montero²² and Sara Marsal¹, ¹Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ²Hospital Universitario Guadalajara, Guadalajara, Spain, ³Arthritis Unit. Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, ⁴Rheumatology, Hospital Regional Carlos Haya, Biomedical Research Institute of Malaga (IBIMA), Malaga, Spain, ⁵Complejo Hospitalario Juan Canalejo, A Coruña, Spain, ⁶Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, ⁷Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, ⁸Hospital Parc Taulí, Sabadell, Spain, ⁹Rheumatology, Hospital del Mar, Barcelona, Spain, ¹⁰Rheumatology Department. Hospital Universitario Central de Asturias, Oviedo, Spain, ¹¹Rheumatology Department, Hospital Universitario Central de Asturias, Oviedo, Spain, ¹²H. de Salamanca, Salamanca, Spain, ¹³Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, ¹⁴Rheumatology Department, H. Monte Naranco, Oviedo, Spain, ¹⁵Rheumatology Service, Germans Trias Pujol Hospital, Barcelona, Spain, ¹⁶Rheumatology Department, Hospital del SAS Jerez de la Frontera, Cadiz, Spain, ¹⁷Rheumatology, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain, ¹⁸Rheumatology Department, Hospital Sant Rafael, Barcelona, Spain, ¹⁹Rheumatology Department, Hospital Infanta Sofia, Madrid, Spain, ²⁰Rheumatology Department, Gregorio Marañon Hospital, Madrid, Spain, ²¹Rheumatology Service, Hospital Moisès Broggi,, Barcelona, Spain, ²²Banco Nacional de ADN, Salamanca, Spain
Background/Purpose: Rheumatoid arthritis (RA) and Psoriatic arthritis (PsA) are complex diseases of unknown etiology and its pathogenesis results from the combination of genetic susceptibility and…
Abstract Number: 2657 • 2013 ACR/ARHP Annual Meeting
Interactions Between Cigarette Smoking, Body Mass Index and Inflammatory Cytokine Levels In Determining The Risk Of Developing Rheumatoid Arthritis
Elizabeth V. Arkema¹, Susan Malspeis², Bing Lu³, Linda T. Hiraki⁴, Elizabeth W. Karlson² and Karen H. Costenbader², ¹Epidemiology, Harvard School of Public Health, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ³Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA
Background/Purpose: Smoking and high body mass index (BMI) are risk factors for RA. Both are associated with increased systemic inflammation, with elevated C-reactive protein, interleukin…
Abstract Number: 2421 • 2013 ACR/ARHP Annual Meeting
Association Between Physical Work Load and Rheumatoid Arthritis, Results From The EIRA Case Control Study
Annmarie Wesley¹, Henrik Källberg², Camilla Bengtsson², Eva Skillgate¹, Johan Rönnelid³, Mohammed Mullazehi⁴, Lars Klareskog⁵, Lars Alfredsson², Saedis Saevarsdottir⁶ and Sara Wedren^7,8, ¹Institute of Enviornmental Medicine, Karolinska Insitutet, Stockholm, Sweden, ²Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ³Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, ⁴Uppsala University, Uppsala, Sweden, ⁵Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁶Rheumatology Unit, Dept. of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁷Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, ⁸Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: The association between occupation and RA has previously been investigated where occupations associated with a physical work load (quarry workers, construction workers, assistant nurses,…
Abstract Number: 2397 • 2013 ACR/ARHP Annual Meeting
To Which Extent May The Familial Risk Of Rheumatoid Arthritis Be Explained By Established Risk Factors?
Xia Jiang¹, Thomas Frisell², Johan Askling³, Lars Klareskog⁴, Lars Alfredsson¹ and Henrik Källberg¹, ¹Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ²Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, ³Karolinska Institutet, Stockholm, Sweden, ⁴Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Rheumatoid arthritis (RA) is a complex inflammatory disease known to aggregate within families, implicating the crucial role of shared genetic and/or environmental factors in…
Abstract Number: 2271 • 2013 ACR/ARHP Annual Meeting
Dietary Sodium Increases The Risk For Rheumatoid Arthritis Among Smokers – Results From a Nested Case-Control Study
Björn Sundström¹, Ingegerd Johansson² and Solbritt Rantapää Dahlqvist³, ¹Department of Public Health & Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, ²Department of Odontology, Cariology, Umeå Universitet, Umeå, Sweden, ³Department of Public Health and Clinical Medicine/Rheumatology, Umeå University Hospital, Umeå, Sweden
Background/Purpose: Recent studies using animal models and human cells ex vivo have indicated that sodium chloride may affect the immune system by the inducting of pathogenic Th17…
Abstract Number: 2000 • 2013 ACR/ARHP Annual Meeting
Changes In The Prevalence Of Gout In The United States General Population Between 1960 and 2010: The National Health and Nutrition Examination Surveys
Eswar Krishnan and Linjun Chen, Medicine, Stanford University, Palo Alto, CA
Background/Purpose: Despite the widely shared impression that the prevalence of gouty arthritis (gout) has increased over time in the US few population data are available.…
Abstract Number: 1773 • 2013 ACR/ARHP Annual Meeting
The Contribution Of Environmental Factors To Familial Risk Of Rheumatoid Arthritis By Serologic Phenotypes Among Women In a Longitudinal Cohort Study
Jeffrey A. Sparks¹, Chia-Yen Chen², Linda T. Hiraki³, Susan Malspeis⁴, Karen H. Costenbader⁴ and Elizabeth W. Karlson¹, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Epidemiology, Harvard School of Public Health, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, ⁴Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Familial risk of RA is composed of shared genetic and environmental factors. Previous studies exploring familial risk of RA have not incorporated environmental factors…
Abstract Number: 1210 • 2012 ACR/ARHP Annual Meeting
Effect of HLA-DRB1*0901 Suggest Distinctive Mechanisms of Rheumatoid Arthritis Susceptibility
So-Young Bang¹, Hye-Soon Lee², Kyung Wha Lee³ and Sang-Cheol Bae⁴, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ³Hallym Institute for Genome Application,Hallym University Sacred Heart Hospital, Anyang, South Korea, ⁴Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Although HLA-DRB1 shared epitope (SE) alleles and DRB1*0901 have repeatedly been shown to be associated with RA susceptibility, the effect of each allele on…
Abstract Number: 976 • 2012 ACR/ARHP Annual Meeting
Effect of Interactions Between Validated Rheumatoid Arthritis Genetic Factors and Environmental Factors On Rheumatoid Arthritis Risk
Chia-Yen Chen¹, Linda T. Hiraki², Susan Malspeis³, Jing Cui⁴, Bing Lu⁴, Robert M. Plenge⁵, Karen H. Costenbader⁴ and Elizabeth W. Karlson⁶, ¹Department of Epidemiology, Harvard School of Public Health, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, ³Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ⁶Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Studies have shown associations between environmental factors and rheumatoid arthritis (RA) risk. Also, genome-wide association studies (GWAS) have identified genetic markers associated with RA…
Abstract Number: 2692 • 2012 ACR/ARHP Annual Meeting
Diet and Other Lifestyle Related Factors and the Risk of Developing Rheumatoid Arthritis
Björn Sundström¹, Ingegerd Johansson² and Solbritt Rantapää Dahlqvist³, ¹Department of Public Health & Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, ²Department of Odontology, Cariology, Umeå Universitet, Umeå, Sweden, ³Department of Public Health and Clinical Medicine/Rheumatology, Umeå University Hospital, Umeå, Sweden
Background/Purpose: There is a growing interest in the role of lifestyle in developing chronic diseases, such as rheumatoid arthritis (RA). Our aim was to investigate…
Abstract Number: 2141 • 2012 ACR/ARHP Annual Meeting
Effects of Cigarette Smoking On EARLY Arthritis (CONAART)
Maria Haye Salinas¹, Ana C. Alvarez¹, Rafael Chaparro del Moral², Mariana Benegas², Christian A. Waimann³, Rodolfo Perez Alamino⁴, Rodrigo Garcia Salinas⁵, Ana Lucía Barbaglia⁶, Veronica Bellomio⁷, Josefina Marcos⁸, Adrian Salas⁹, Cristian Quiroz¹⁰, Federico Ceccato¹¹, Sergio Paira¹¹, Dora Lia Vazquez¹², Gabriela Salvatierra¹³, M. Crespo¹⁴, Edson Javier Velozo¹⁵, Oscar L. Rillo¹⁶, Enrique Soriano¹⁷, Antonio Catalan Pellet⁵, Alberto Berman Sr.¹⁸, Juan Carlos Marcos¹⁹, Gustavo Citera²⁰ and Francisco Caeiro²¹, ¹Rheumatology, Hospital Privado, Córdoba, Argentina, ²Rheumatology, Hospital Tornu, Buenos Aires, Argentina, ³Rheumatology section, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Rheumatology, Louisiana State University, New Orleans, LA, ⁵Rheumatology, Hospital Rivadavia, Buenos Aires, Argentina, ⁶Rheumatology, Hospital Padilla, Tucuman, Argentina, ⁷Centro Medico Privado de Reumatologia, Tucuman, Argentina, ⁸Rheumatology Unit, HIGA San Martín La Plata, La Plata, Argentina, ⁹Hospital San Martin, La Plata, Argentina, ¹⁰Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹¹Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, ¹²Rheumatology, Centro Integral de Reumatologia, Santiago del Estero, Argentina, ¹³Rheumatology, Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina, ¹⁴Rheumatology, Hospital Señor del Milagro, Salta, Argentina, ¹⁵Rheumatology, Sanatorio Adventista del Plata, Entre Rios, Argentina, ¹⁶Rheumatology, Hospital General de Agudos "Dr. E. Tornú", Buenos Aires, Argentina, ¹⁷Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹⁸Internal Medicine, Hospital Padilla, Tucuman, Argentina, ¹⁹Rheumatology, Hospital San Martin, La Plata, Argentina, ²⁰Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²¹Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina
Background/Purpose: According to recent reports the cigarette smoking persons have 2-4 times greater risk of developing rheumatoid arthritis (RA). The cigarette smoking is associated with…
Abstract Number: 1692 • 2012 ACR/ARHP Annual Meeting
Lung Microbiome Differs in Subjects with Rheumatoid Arthritis-Related Autoimmunity without Inflammatory Arthritis Compared to Healthy Seronegative Controls
M. Kristen Demoruelle¹, Jill M. Norris², V. Michael Holers³, Kevin D. Deane¹ and J. Kirk Harris⁴, ¹Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ²Epidemiology, Colorado School of Public Health, Aurora, CO, ³Rheumatology Division, University of Colorado School of Medicine, Aurora, CO, ⁴University of Colorado Anschutz Medical Campus, Aurora, CO
Background/Purpose: Emerging data suggest that microorganisms and mucosal inflammation may play a role in the etiology of rheumatoid arthritis (RA). Furthermore, our published findings…

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