Abstracts tagged "Enthesitis"

Abstract Number: 2417 • 2015 ACR/ARHP Annual Meeting
Induction and Maintenance of Remission By Etanercept in Enthesitis Related Arthritis JIA-Patients
Gerd Horneff¹, Ivan Foeldvari², Kirsten Minden³, Ralf Trauzeddel⁴, J B. Kuemmerle-Deschner⁵, Klaus Tenbrock⁶, Gerd Ganser⁷ and Hans-Iko Huppertz⁸, ¹Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, ²Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, ³DRFG, Berlin, Germany, ⁴HELIOS Klinikum Berlin-Buch Klinik fuer Kinder- und Jugendmedizin, Berlin, Germany, ⁵Pediatrics, University Hospital Tuebingen, Tuebingen, Germany, ⁶University Aachen, Aachen, Germany, ⁷Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, ⁸PRINTO, IRCCS G. Gaslini, Genoa, Italy
Background/Purpose: Enthesitis-related arthritis (ERA) is a juvenile idiopathic arthritis (JIA) category affecting entheses and joints. The REMINDER study to analyse the efficacy of etanercept (ETA)…
Abstract Number: 2877 • 2015 ACR/ARHP Annual Meeting
What Is the Location of Enthesitis in Ankylosing Spondylitis and Psoriatic Arthritis Patients and How Do They Respond to Anti-TNF Treatment?
John Kelsall¹, Denis Choquette², Proton Rahman³, Regan Arendse⁴, Michelle Teo⁵, Isabelle Fortin⁶, J Antonio Avina-Zubieta⁷, Emmanouil Rampakakis^8,9, Eliofotisti Psaradellis⁹, Karina Maslova¹⁰, Brendan Osborne¹¹, Cathy Tkaczyk¹¹, Francois Nantel¹² and Allen J Lehman¹⁰, ¹Mary Pack Arthritis Centre, Vancouver, Vancouver, BC, Canada, ²Rheumatology Department, Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, ³Medicine, Memorial University, St John's, NF, Canada, ⁴University of Saskatchewan, Saskatoon, SK, Canada, ⁵Rheumatology, Penticton Regional Hospital, Penticton, BC, Canada, ⁶Centre de Rhumatologie de l'Est du Québec, Rimouski, QC, Canada, ⁷Arthritis Research Canada, Richmond, BC, Canada, ⁸JSS Medical Research, St-Laurent, QC, Canada, ⁹JSS Medical Research, Montreal, QC, Canada, ¹⁰Janssen Inc., Toronto, ON, Canada, ¹¹Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹²19 Green belt Dr, Janssen Inc., Toronto, ON, Canada
Background/Purpose: Enthesitis is characterized by inflammation at the insertion of ligaments, tendons, joint capsule, or fascia to bone, and represents a well-known characteristic feature of…
Abstract Number: 674 • 2015 ACR/ARHP Annual Meeting
Clinical Characteristics of Japanese Patients with Reactive Arthritis Induced By Intravesical BCG Therapy for Bladder Cancer: A 19 Years Two-Center Retrospective Study
Hirofumi Nishikawa¹, Yoshinori Taniguchi¹, Takashi Karashima², Tetsushi Aita³, Susumu Nishiyama³, Yasuhiko Yoshinaga³, Yoshitaka Kumon⁴, Yoshiko Shimamura¹, Kosuke Inoue¹, Taro Horino¹, Taro Shuin² and Yoshio Terada¹, ¹Kochi University, Nankoku, Japan, ²Urology, Kochi University, Nankoku, Japan, ³Kurashiki Medical Center, Kurashiki, Japan, ⁴Chikamori Hospital, Kochi, Japan
Background/Purpose: Intravesical instillation of BCG is used as an effective immunotherapy of bladder cancer. However it may have, as adverse event, a reactive arthritis (ReA)…
Abstract Number: 678 • 2015 ACR/ARHP Annual Meeting
Clinical Characteristics and Disease Activity in Psoriatic Arthritis Patients with Dactylitis or Enthesitis: Results from Corrona Registry
Philip J. Mease¹, Chitra Karki², Carol J. Etzel^2,3, Arthur Kavanaugh⁴, Christopher T. Ritchlin⁵, Wendi Malley², Vivian Herrera⁶, Jacqueline B. Palmer⁶ and Jeffrey D. Greenberg^2,7, ¹Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, ²Corrona, LLC, Southborough, MA, ³The University of Texas MD Anderson Cancer Center, Houston, TX, ⁴University of California San Diego, La Jolla, CA, ⁵Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY, ⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁷New York University School of Medicine, Millburn, NJ
Background/Purpose: Psoriatic arthritis (PsA) exhibits considerable heterogeneity in its presentation and course, which contributes to the complexity of diagnosis and assessment. Enthesitis, inflammation at the…
Abstract Number: 1471 • 2015 ACR/ARHP Annual Meeting
Phenotypic Differences Between HLA-B27 Positive and Negative Children with Enthesitis-Related Arthritis
Sabrina Gmuca¹, Timothy Brandon², Rui Xiao³, Ilaria Pagnini⁴, Tracey B. Wright⁵, Timothy Beukelman⁶, Esi Morgan-DeWitt⁷ and Pamela F. Weiss⁸, ¹Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, ²Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ⁴Department of Paediatrics, University of Florence and Anna Meyer Children's Hospital, Florence, Italy, Florence, Italy, ⁵Pediatrics/Rheumatology, UT Southwestern Medical Center, Dallas, TX, ⁶Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁷Pediatric rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁸Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: The association of HLA-B27 with spondyloarthritis is well-established. Under the International League of Associations for Rheumatology (ILAR) criteria most children with spondyloarthritis are classified…
Abstract Number: 1718 • 2015 ACR/ARHP Annual Meeting
Entheseal Abnormalities and Nail Involvement at the Distal Interphalangeal Joints on Ultrasound Examination in Patients with Psoriasis and Psoriatic Arthritis. Could the Nail-Enthesitis Theory be Supported?
M Laura Acosta-Felquer¹, Erika Catay², Leandro Ferreyra-Garrot³, Santiago Ruta¹, David A. Navarta⁴, Javier Rosa⁵, Ricardo Galimberti⁶, Maria L. Galimberti⁶, Ricardo Garcia-Monaco⁷ and Enrique R. Soriano⁸, ¹Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio,, Buenos Aires, Argentina, ³Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Internal Medicine, Argentina, Buenos Aires, Argentina, ⁴Internal Medicine, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Dermatology Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁸Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: It has been shown that nail involvement in psoriasis is associated with systemic enthesopathy. The association of enthesopathy and nail disease at distal…
Abstract Number: 3008 • 2014 ACR/ARHP Annual Meeting
High Prevalence of Subclinical Ultrasonographic Enthesopathy and Synovitis in Patients with Inflammatory Bowel Disease without Clinical Signs or Symptoms of Spondyloarthritis
Esther Vicente¹, Silvia Pérez-Esteban², María Chaparro³, Francisco Rodríguez-Salvanés⁴, Lorena Vega⁴, Santos Castañeda¹ and Javier P Gisbert⁵, ¹Rheumatology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, ²Rheumatology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, ³Gastroenterology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, ⁴Epidemiologic Research Unit, Hospital Universitario de La Princesa, IISP, Madrid, Spain, ⁵Gastroenterology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain
Background/Purpose Musculoskeletal manifestations as peripheral arthritis, axial disease and enthesitis are present in 10-62% of Inflammatory Bowel Disease (IBD) patients. Ultrasonography is more sensitive than…
Abstract Number: 2302 • 2014 ACR/ARHP Annual Meeting
Classification of Juvenile Spondyloarthropathies According to ASAS Criteria
Marìa M. Katsicas¹ and Ricardo A. G. Russo², ¹Immunology & Rheumatology., Hospital de Pediatrìa Garrahan, Buenos Aires, Argentina, ²Immunology & Rheumatology, Hospital de Pediatria Garrahan, Buenos Aires, Argentina
Background/Purpose The juvenile spondyloarthropathies (JSpA) are a group of related seronegative rheumatic diseases characterized by involvement of the axial , peripheral large joints and entheses.…
Abstract Number: 1574 • 2014 ACR/ARHP Annual Meeting
University Students with Psoriatic Nail Changes Have a Greater Number of Tender Enthesial Points Than Those with Normal Nails
A Eftal Yucel¹, Melih Pamukcu², Elif Durukan³, Busra Tosun⁴, Berk Batman⁴, Omer Ozkan⁴ and Anil Kocak⁴, ¹Int Medicine Rheumatology, Baskent University Faculty of Medicine, Ankara, Turkey, ²Internal Medicine Rheumatology, Baskent University Faculty of Medicine, Ankara, Turkey, ³Public Health, Baskent University Faculty of Medicine, Ankara, Turkey, ⁴Baskent University Faculty of Medicine, Ankara, Turkey
Background/Purpose Nail pitting is present in about 10% of healthy adults, and more than 50% of patients with psoriatic arthritis. We believe that the prevalence…
Abstract Number: 1545 • 2014 ACR/ARHP Annual Meeting
Better Performance of the Leeds and Sparcc Enthesitis Indices Compared to the Mases in Patients with Peripheral Spondyloarthritis during Treatment with Adalimumab
Philip J. Mease¹, Filip van Den Bosch², Joachim Sieper³, Aileen L. Pangan⁴, Nupun A. Varothai⁴ and In-Ho Song⁵, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Ghent University Hospital, Ghent, Belgium, ³Charité Universitätsmedizin Berlin, Berlin, Germany, ⁴AbbVie Inc., North Chicago, IL, ⁵AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany
Background/Purpose: Peripheral spondyloarthritis (pSpA) is characterized by arthritis, enthesitis, and/or dactylitis. Enthesitis is considered a core outcome domain for SpA; however, there is no clear…
Abstract Number: 1550 • 2014 ACR/ARHP Annual Meeting
Prevalence of Enthesitis and Dactylitis, Impact on Disease Severity and Evolution over 12 Months in Psa Patients Treated with Anti-TNF in a Real-World Setting
Proton Rahman¹, Denis Choquette², William Bensen³, Majed Khraishi⁴, Saeed Shaikh⁵, Regan Arendse⁶, Isabelle Fortin⁷, Andrew Chow⁸, Maqbool Sheriff⁹, Eliofotisti Psaradellis¹⁰, John S. Sampalis¹⁰, Susan Otawa¹¹, Francois Nantel¹², Allen J Lehman¹¹ and May Shawi¹², ¹Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ²Rheumatology, Notre Dame Hospital, Montreal, QC, Canada, ³Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁴Nexus Clinical Research, St John's, NF, Canada, ⁵McMaster University, Hamilton, ON, Canada, ⁶University of Saskatchewan, Saskatoon, SK, Canada, ⁷Centre de Rhumatologie de l'Est du Québec, Rimouski, QC, Canada, ⁸University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, ⁹Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ¹⁰JSS Medical Research, Montreal, QC, Canada, ¹¹Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹²Janssen Inc., Toronto, ON, Canada
Background/Purpose Spondyloarthritis, including psoriatic arthritis (PsA), is characterized by inflammatory arthritis affecting axial and peripheral joints. It is commonly associated with extra-articular and peri-articular manifestations…
Abstract Number: 1559 • 2014 ACR/ARHP Annual Meeting
Long Term Improvements in Physical Function Are Associated with Improvements in Dactylitis, Enthesitis, Tender and Swollen Joint Counts, and Psoriasis Skin Involvement: Results from a Phase 3 Study of Ustekinumab in Psoriatic Arthritis Patients
Arthur Kavanaugh¹, Lluís Puig Sanz², Alice B. Gottlieb³, Christopher T. Ritchlin⁴, Shu Li⁵, Yin You⁵, Alan M. Mendelsohn⁶, Michael Song⁵, Proton Rahman⁷ and Iain B. McInnes⁸, ¹University of California San Diego, La Jolla, CA, ²Dermatology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ³Tufts Medical Center, Boston, MA, ⁴Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Janssen Research & Development, LLC., Spring House, PA, ⁶Immunology, Janssen Research & Development, LLC., Spring House, PA, ⁷Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁸Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: To evaluate the association of improvements in tender and swollen joint counts (TJC, SJC), psoriasis skin involvement, and dactylitis/enthesitis (in patients affected at baseline)…
Abstract Number: 1558 • 2014 ACR/ARHP Annual Meeting
Evaluation of Extreme Enthesitis and/or Patient-Related Outcome Score As Potential Surrogates for Fibromyalgia and As Potential Confounding Factors of Anti-TNF Response
M Dougados¹, H Jones², A Szumski³, I Logeart⁴ and J Coindreau⁵, ¹Université Paris René Descartes and Hôpital Cochin, Paris, France, ²Inflammation & Immunology, Pfizer Inc., Collegeville, PA, ³Pfizer Inc., Collegeville, PA, ⁴Pfizer, Paris, France, ⁵Pfizer Inc., New York, NY
Background/Purpose: Differentiating between pain related to spondyloarthritis (in particular polyenthesitis) and pain related to fibromyalgia can be challenging, both in daily practice and in clinical…
Abstract Number: 308 • 2014 ACR/ARHP Annual Meeting
Tenascin-C, a TLR4 Ligand Levels in Enthesitis Related Arthritis Category of Juvenile Idiopathic Arthritis: Cross-Sectional and Longitudinal Study
Anuj Shukla¹, Priyanka Gaur² and Amita Aggarwal¹, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose Tenascin-C (TNC) is an extracellular matrix glycoprotein, which binds to TLR4 and leads to its activation. Monocytes of children with Enthesitis related arthritis (ERA)…
Abstract Number: 270 • 2014 ACR/ARHP Annual Meeting
Disease Burden Is Comparable in Children with Enthesitis-Related Arthritis and Polyarticular Juvenile Idiopathic Arthritis
Pierre Quartier¹, Jasmina Kalabic², Zbigniew Zuber³, Kirsten Minden⁴ and Jaclyn K. Anderson⁵, ¹Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, ²AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, ³St. Louis Children’s Hospital, Krakow, Poland, ⁴Charité Universitätsmedizin Berlin, Berlin, Germany, ⁵AbbVie Inc., North Chicago, IL
Background/Purpose: To compare baseline disease characteristics of pediatric patients (pts) with enthesitis-related arthritis (ERA) and polyarticular juvenile idiopathic arthritis (pJIA) from clinical trials with adalimumab…

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