ACR Meeting Abstracts

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Abstracts tagged "DMARDs"

  • Abstract Number: 2555 • 2016 ACR/ARHP Annual Meeting

    Efficacy and Safety of Conventional and Targeted Synthetic Disease-Modifying Antirheumatic Drugs As Well As Glucocorticoids: A Systematic Literature Review Informing the 2016 Update of the Eular Recommendations for the Management of Rheumatoid Arthritis

    Katerina Chatzidionysiou1, Sharzad Emamikia2, Jackie L. Nam3, Sofia Ramiro4, Josef Smolen5, Désirée van der Heijde6, Maxime Dougados7, Johannes WJ Bijlsma8, Gerd Burmester9, Marieke Scholte-Voshaar10, Ronald van Vollenhoven11,12 and Robert Landewé13, 1Karolinska Institute, Stockholm, Sweden, 2Department of Medicine, Karolinska Institute, Stockholm, Sweden, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Leiden University Medical Center, Leiden, Netherlands, 5Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 6Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 7Paris Descartes University, Paris, France, 8Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 9Charité University Hospital, Berlin, Germany, 10EULAR Standing Committee of People with Arthritis/Rheumatism in Europe, Zurich, Switzerland, 11Amsterdam Rheumatology Center, Amsterdam, Netherlands, 12Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden, 13Clinical Immunology and Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands

    Background/Purpose: To inform the task force for the 2016 update of the EULAR recommendations for the management of RA on the evidence regarding the efficacy…
  • Abstract Number: 137 • 2016 ACR/ARHP Annual Meeting

    Imaging Remission By Musculoskeletal Ultrasound Leads to a Better Functional Outcome – Results of the US Impera Study – US 7-Score Implementation Study in Early Rheumatoid Arthritis

    Anne-Marie Glimm1, Sarah Ohrndorf2, Imma Fischer3, Johannes Strunk4, Wolfgang A. Schmidt5, Wolfgang Hartung6, Herbert Kellner7, Horst Sattler8, Gabriela Schmittat1, GR Burmester9 and Marina Backhaus10, 1Department of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany, 2Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, 3Biostatistik Tuebingen, Tuebingen, Germany, 4Department of Rheumatology, Hospital 'Porz am Rhein', Academic Hospital of the University of Cologne, Cologne, Germany, 5Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 6Department of Rheumatology and Clinical Immunology, Asklepios Klinik Bad Abbach, Bad Abbach, Germany, 7Department of Internal Medicine – Rheumatologic Day Clinic, Krankenhaus Neuwittelsbach, Academic Hospital of Ludwig-Maximilians-University Munich, Munich, Germany, 8Internal Medicine and Rheumatology Practice, Bad Duerkheim, Bad Duerkheim, Germany, 9Charité – University Medicine Berlin, Berlin, Germany, 10Department of Rheumatology & Immunology, University Medicine Charit, Berlin, Germany

    Background/Purpose: Novel treat-to-target strategies present new challenges to treatment monitoring in rheumatoid arthritis (RA). To compare functional outcomes in early RA patients monitored by standard…
  • Abstract Number: 1981 • 2016 ACR/ARHP Annual Meeting

    A Pilot Pulsed Arterial Spin Labeling Study of Regional Cerebral Blood Flow in Response to Pain in RA, before and after DMARD Treatment

    Yvonne C. Lee1, Alexander Fine2, Ekaterina Protsenko3, Elena Massarotti4, Robert R. Edwards5, Vitaly Napadow6 and Marco Loggia3, 1Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 3Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, 4Rheumatology Immunology & Allergy, Brigham & Women's Hospital, Boston, MA, 5Anesthesiology, Brigham & Womens Hospital, Chestnut Hill, MA, 6Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA

    Background/Purpose: Although significant advances have been made in treating inflammation in RA, little is known about central nervous system (CNS) pain pathways in inflammatory arthritis.…
  • Abstract Number: 2578 • 2016 ACR/ARHP Annual Meeting

    Plasma Levels of Bone Morphogenetic Protein (BMP) Subgroups and Their Inhibitors (noggin, sclerostin) in Rheumatoid Arthritis Patients and Correlation with Disease Activity, Clinical and Radiographic Progression

    Ozge Kockara1, Merve Sibel Gungoren2, Erdem Karabulut3, Sebnem Ataman4 and Filiz Akbiyik2, 1Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Turkey, 2Medical Biochemistry, Hacettepe University Faculty of Medicine, Ankara, Turkey, 3Biostatistics, Hacettepe University Faculty of Medicine, Ankara, Turkey, 4Rheumatology Department, Ankara University Faculty of Medicine, Ankara, Turkey

    Background/Purpose: Progressive bone destruction occurs in rheumatoid arthritis (RA) due to imbalance of osteoblast/osteoclast activity. Bone morphogenetic proteins (BMPs) regenerate bone damage by stimulating the…
  • Abstract Number: 566 • 2016 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Patients’ Ability to Accurately Recall DMARD Information Immediately Following an Office Visit with Their Rheumatologist

    Delesha Carpenter1, Lorie Geryk2, Courtney Roberts2, Beth L. Jonas3 and Susan J. Blalock4, 1Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Asheville, NC, 2Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, 3Thurston Arthritis Research Ct, University of North Carolina Thruston Arthritis Research Center, Chapel Hill, NC, 4Eshelman School of Pharmacy, UNC at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Patient misunderstandings about DMARDs may contribute to nonadherence. We present longitudinal observational data regarding whether patients can accurately recall medication information about a newly-prescribed…
  • Abstract Number: 1991 • 2016 ACR/ARHP Annual Meeting

    Risk of Incident Diabetes Mellitus and Its Association with Disease-Modifying Antirheumatic Drugs and Statins in Rheumatoid Arthritis

    Gulsen Ozen1,2, Sofia Pedro3, Marie Holmqvist4, Frederick Wolfe3 and Kaleb Michaud2,3, 1Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Rheumatology, University of Nebraska Medical Center, Omaha, NE, 3National Data Bank for Rheumatic Diseases, Wichita, KS, 4Dept of Medicine, Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Diabetes mellitus (DM) is an important cardiovascular risk factor in RA. Although a few prior studies reported DM risk reduction with hydroxychloroquine (HCQ) and…
  • Abstract Number: 2607 • 2016 ACR/ARHP Annual Meeting

    Favorable Changes in Lipid Profile with Additive DMARD Therapy in Rheumatoid Arthritis Patients Failing Methotrexate Monotherapy

    Tate Johnson1, Ted R Mikuls2, Harlan Sayles1, Michael J. Duryee3, Geoffrey M. Thiele1, Mary Brophy4,5 and James R. O'Dell6, 1University of Nebraska Medical Center, Omaha, NE, 2Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 3Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 4VA Boston Heathcare System, Boston, MA, 5MAVERIC CSPCC (151MAV), VA Boston Healthcare System, Boston, MA, 6Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Cardiovascular disease is a significant comorbidity among RA patients. As such, dyslipidemia and the effect of DMARD therapy on lipid profiles is an important…
  • Abstract Number: 607 • 2016 ACR/ARHP Annual Meeting

    The Clinical Response to Biologic and Non-Biologic Disease Modifying Antirheumatic Drugs (DMARDs) According to Gender in a French-Canadian Population with Rheumatoid Arthritis (RA)

    Sonia Lagacé1, Louis Bessette2,3, Louis Coupal4 and Denis Choquette4, 1Medicine, Laval University, Quebec, QC, Canada, 2Rheumatology, Laval University, Québec, QC, Canada, 3Rhumatologie, CHU de Québec - Université Laval, Quebec, QC, Canada, 4Rheumatology, Institut de Recherche en Rhumatologie de Montréal (IRRM), Montréal, QC, Canada

    Background/Purpose: Several studies have reported that women with RA had higher level of pain, disease activity and functional impairment compared to men. In addition, women…
  • Abstract Number: 1999 • 2016 ACR/ARHP Annual Meeting

    Claims-Based Analysis of Cost-Effectiveness Among Patients with Rheumatoid Arthritis Who Switched from a Tumor Necrosis Factor Inhibitor to Another Targeted Disease-Modifying Antirheumatic Drug

    Machaon Bonafede1, Wenhui Wei2, Chieh-I Chen3, Donna McMorrow1, Stefano Fiore4, Jonathan Fay3, Toshio Kimura3 and Jeffrey R. Curtis5, 1Truven Health Analytics, Cambridge, MA, 2Sanofi US, Inc., Bridgewater, NJ, 3Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 4Sanofi Genzyme, Bridgwater, NJ, 5Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Patients with rheumatoid arthritis (RA) who have an inadequate response to a tumor necrosis factor inhibitor (TNFi) can switch to another targeted disease-modifying antirheumatic…
  • Abstract Number: 2624 • 2016 ACR/ARHP Annual Meeting

    Anti-Citrullinated Protein Antibodies Titers Are Independently Modulated By Disease Activity and Synthetic or Biologic Dmards in a Seropositive Early Arthritis Population

    Elena García Lorenzo1, Daniel Useros2, Aranzazu Alfranca3, Ana M. Ortiz Garcia1, Pablo Moreno Fresneda1, Isidoro Gonzalez-Alvaro1 and Rosario García-Vicuña1, 1Rheumatology, Rheumatology Service, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, 2Rheumathology, Rheumatology Service, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, 3Immunology, Immunology Service, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain

    Background/Purpose: Early introduction of some biologic (b) DMARDs has been proposed to reduce anti-citrullinated protein antibodies (ACPA) titers in clinical trials settings. However, less information…
  • Abstract Number: 611 • 2016 ACR/ARHP Annual Meeting

    Analysis of a German Subpopulation with Active Rheumatoid Arthritis Treated with Golimumab As Add-on Therapy to Disease-Modifying Antirheumatic Drugs

    Hendrik Schulze-Koops1, Jürgen Wollenhaupt2, Marita Winnemöller3, Ines Klaudius3 and Helena Löffler3, 1Division of Rheumatology, Division of Rheumatology and Clinical Immunology, Medizinische Klinik und Poliklinik IV, University of Munich, Munich, Germany, 2Schön Klinik Hamburg-Eilbek, Hamburg, Germany, 3Medical Affairs, MSD Sharp & Dohme GmbH, Haar, Germany

    Background/Purpose: In previous clinical studies the human monoclonal TNFα-antibody golimumab (GLM) showed a good clinical response and a favorable benefit:risk profile in the treatment of…
  • Abstract Number: 2001 • 2016 ACR/ARHP Annual Meeting

    Perioperative Use of Synthetic Disease-Modifying Anti-Rheumatic Drugs or Tumor Necrosis Factor α Inhibitors Does Not Associate with Increased Rates of Post-Operative Infections

    Hsin-Hsuan Juo1,2, Anders Peck3,4, Nancy Gove5 and Bernard Ng1,2, 1Division of Rheumatology, Department of Medicine, University of Washington, Seattle, WA, 2Rheumatology, VA Puget Sound Healthcare System, Seattle, WA, 3Medicine / Rheumatology, University of Washington, Seattle, WA, 4The Seattle Arthritis Clinic, Seattle, WA, 5Biostatistics, Seattle Children's Research Institute, Seattle, WA

    Background/Purpose: The aim of the study is to assess whether the risk of post-operative infectious complications in rheumatoid arthritis (RA) patients undergoing surgical procedures is…
  • Abstract Number: 2643 • 2016 ACR/ARHP Annual Meeting

    Risk Factors of Pneumocystis Jiroveci Pneumonia (PJP) in Patients with RA and Sulfasalazine As a Possible Protective Agent

    Shinji Motojima1, Tamao Nakashita2, Akira Jibatake1, Akira Yoshida1 and Yoshiki Yamamoto1, 1Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan, 2Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa-city, Japan

    Background/Purpose:  Pneumocystis jiroveci pneumonia (PJP) is a serious complication during the treatment in patients with variety of rheumatic disease. Postmarketing surveillance of infliximab and etnercept…
  • Abstract Number: 701 • 2016 ACR/ARHP Annual Meeting

    In Patients with Ankylosing Spondylitis Treated with Adalimumab, Combination Therapy with DMARD, Increase the Serum Level of Adalimumab and Decrease Immunogenicity

    José Rosas1, Francisca Llinares-Tello2, José Miguel Senabre-Gallego1, Mariana Marco-Mingot3, Ana Pons1, Xavier Barber4, Gregorio Santos-Soler1, Esteban Salas-Heredia1, Catalina Cano1, Juan Molina3, Marina Sanchís4, Mario García-Carrasco5 and AIRE-MB Group, 1Rheumatology, Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 2Laboratory, Hospital Marina Baixa, Villajoyosa, Spain, 3Laboratory, Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 4CIO, Universidad Miguel Hernández, Elche, Spain, 5Systemic Autoimmune Diseases Research Unit, HGR 36-CIBIOR Instituto Mexicano del Seguro Social, Puebla, Mexico

    Background/Purpose: In patients with rheumatoid arthritis, methotrexate (MTX), improves the clinical efficacy of anti-TNF (TNFi), among other reasons, for reducing the immunogenicity. However, there are…
  • Abstract Number: 2081 • 2016 ACR/ARHP Annual Meeting

    Dermal Temperature Is an Excelent Prognostic Indicator to Guide RA Therapy

    JoAnn Ball1 and Maria Greenwald2, 1rheumatology, Desert Medical Advances, Palm Deseret, CA, 2Rheumatology, Desert Medical Advances, Palm Desert, CA

    Background/Purpose: Nurses and rheumatology extenders can rapidly identify rheumatoid arthritis (RA) patients who flare, with high predictive value for which individual is at high risk…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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