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Abstracts tagged "Disease Activity"

  • Abstract Number: 2642 • 2017 ACR/ARHP Annual Meeting

    Lupus Serum Induces Glomerular Endothelial Cell Neutrophil Adhesion in Association with Soluble Mediators of Chemotaxis and Adhesion

    Dayvia Russell1, Margaret Markiewicz2 and Jim C. Oates3,4, 1Research Service, Ralph H. Johnson VA Medical Center, Charleston, SC, 2Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, 3Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, 4Medical Service, Ralph H. Johnson VA Medical Center, Charleston, SC

    Background/Purpose: Systemic lupus erythematosus (SLE) is associated with endothelial dysfunction, which can accelerated inflammation. Ingress of neutrophils into tissue requires chemotaxis and adhesion to endothelial…
  • Abstract Number: 2970 • 2017 ACR/ARHP Annual Meeting

    Inhibition of Radiographic Progression in Psoriatic Arthritis By Adalimumab Independent of the Control of Clinical Disease Activity

    Robert B.M. Landewé1, Christopher T. Ritchlin2, Laura C Coates3, Daniel Aletaha4, Benoît Guérette5, Ying Zhang5, Fabiana Ganz6 and Maja Hojnik7, 1University of Amsterdam, Amsterdam, Netherlands, 2Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, 3University of Leeds and Leeds Teaching Hospitals NHS Trust, Leeds, Great Britain, 4Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 5AbbVie Inc., North Chicago, IL, 6AbbVie AG, Baar, Switzerland, 7AbbVie, Ljubljana, Slovenia

    Background/Purpose : Patients (pts) with psoriatic arthritis (PsA) may experience structural damage and irreversible functional impairment if not treated appropriately. Treatment with TNF inhibitors in…
  • Abstract Number: 427 • 2017 ACR/ARHP Annual Meeting

    Do We Treat Men and Women Differently, and Is This a Good Thing?

    Sytske Anne Bergstra1, Cornelia F Allaart1, Sofia Ramiro2, Arvind Chopra3, Candida A. Silva4, Nimmisha Govind5 and Robert B.M. Landewé6,7, 1Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 2Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 3Center for Rheumatic Diseases, Pune, India, Pune, India, 4Instituto Português de Reumatologia, Lisbon, Portugal, Lisbon, Portugal, 5Department of Rheumatology, University of the Witwatersrand, Johannesburg, South-Africa, Johannesburg, South Africa, 6Zuyderland Medical Center, Heerlen, Netherlands, Heerlen, Netherlands, 7Amsterdam Rheumatology & Immunology Center, Netherlands, Amsterdam, Netherlands

    Background/Purpose: Men seem to respond better to antirheumatic treatment than women with RA. In daily practice, expectations towards responsiveness may influence rheumatologists when making treatment…
  • Abstract Number: 844 • 2017 ACR/ARHP Annual Meeting

    Social Support, Stress and Health Outcomes in Systemic Lupus Erythematosus: Georgians Organized Against Lupus (GOAL) Cohort

    Charmayne M. Dunlop-Thomas, S. Sam Lim, Gaobin Bao and Cristina Drenkard, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA

    Background/Purpose: Stress can influence immune and neuroendocrine processes, and may lead to poor outcomes in people with systemic lupus erythematosus (SLE). Social support can potentially…
  • Abstract Number: 1342 • 2017 ACR/ARHP Annual Meeting

    Comprehensive Provider Judgment Outweighs Disease Activity Measures in the Decision to Not Escalate Therapy in Patients with Moderate to Severe Rheumatoid Arthritis

    Jacob R. Stever1, Brian Sauer2, Chia-Chen Teng, MS1, Neil Accortt3, David Collier4 and Grant Cannon1, 1Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 2IDEAS Center and Division of Epidemiology, HSR&D SLC VA Medical Center and University of Utah, Salt Lake City, UT, 3Center for Observational Research, Amgen, Inc., Thousand Oaks, CA, 4Amgen, Inc., Thousand Oaks, CA

    Title:  Comprehensive provider judgment outweighs disease activity measures in the decision to not escalate therapy in patients with moderate to severe rheumatoid arthritis.   Authors:   Stever,…
  • Abstract Number: 1601 • 2017 ACR/ARHP Annual Meeting

    Hydroxychloroquine Non-Adherence Is Associated with Higher Sledai Scores in a Predominantly Hispanic Population

    Alexandra Perel-Winkler1, Kayla Neville1, James Miceli1, Samantha Nguyen1, Miya Okado1, Laura Geraldino-Pardilla1, Teja Kapoor1, Jon T. Giles2 and Anca Askanase1, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Non-adherence to medication has been shown to impact mortality, morbidity, and health care utilization in SLE and ranges from 40-80% depending on the methods…
  • Abstract Number: 1917 • 2017 ACR/ARHP Annual Meeting

    A Novel Type I Interferon Biomarker on B Cell Predicts with Disease Activity in SLE and Can be Measured By Cell Surface Tetherin (CD317)

    Yasser M El-Sherbiny1,2,3, Md Yuzaiful Md Yusof1, Antonios Psarras1, Elizabeth M.A. Hensor1, Kumba Kabba1, Alaa Mohamed1,4, Miriam Wittmann5, Paul Emery5,6 and Edward M Vital1,5,7, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals, NHS Trust, Leeds, United Kingdom, 3Clinical Pathology dept., School of Medicine, Mansoura University, Mansoura, Egypt, 4Faculty of Medicine, Assiut University, Department of Rheumatology and Rehabilitation, Assiut, Egypt, 5NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 7University of Leeds, Leeds, United Kingdom

    Background/Purpose: SLE is an IFN-I-mediated disease with dysregulated handling of self-nuclear antigens triggering anti-viral immune mechanisms. The level of IFN-I activity appears to stratify for…
  • Abstract Number: 2434 • 2017 ACR/ARHP Annual Meeting

    Baseline Expressions of Cellular microRNA-31 and microRNA-10a Predict Remission and Low Disease Activity in Patients with Early Rheumatoid Arthritis after Six and Twelve Months of Therapy

    Veronika Hruskova1,2, Klara Prajzlerova3, Martin Komarc4, Lucia Vernerova1, Herman F Mann3, Maria Filkova3, Karel Pavelka3, Jiri Vencovsky3 and Ladislav Senolt3, 1Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, 2Faculty of Science, Charles University, Prague, Czech Republic, Prague, Czech Republic, 3Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 4Department of Anthropometrics and Methodology, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic

    Background/Purpose: MicroRNAs (miRNAs) post-transcriptionally regulate gene expression by targeting messenger RNAs. The expression of miRNAs was demonstrated to differ between patients with rheumatoid arthritis (RA)…
  • Abstract Number: 2781 • 2017 ACR/ARHP Annual Meeting

    Assessing RA Disease Activity with Promis Measures Using Smartphone Technology

    Huifeng Yun1, Shuo Yang2, W. Benjamin Nowell3, Cooper Filby1, Lang Chen1 and Jeffrey R. Curtis4, 1University of Alabama at Birmingham, Birmingham, AL, 2Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Global Healthy Living Foundation, Upper Nyack, NY, 4Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Health information technology has enabled efficient measurement of PROs using Computer Adaptive Testing (CAT) methods, which have been shown to minimize missing data and…
  • Abstract Number: 432 • 2017 ACR/ARHP Annual Meeting

    ACPA and RF As Predictors of Sustained Clinical Remission in Rheumatoid Arthritis Patients: Data from a Rheumatoid Arthritis Cohort

    Janet E. Pope1, Emmanouil Rampakakis2, Mohammad Movahedi3, Angela Cesta3, John S. Sampalis4 and Claire Bombardier3, 1Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada, 2JSS Medical Research, Montreal, QC, Canada, 3Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 4McGill University, Montreal, QC, Canada

    ACPA and RF as Predictors of Sustained Clinical Remission in Rheumatoid Arthritis Patients: Data From a Rheumatoid Arthritis CohortBackground/Purpose: Positive serology for anti-citrullinated protein antibody…
  • Abstract Number: 870 • 2017 ACR/ARHP Annual Meeting

    Detection of Left Ventricular Regional Function in Rheumatoid Arthritis Patients without Cardiac Symptons, As Assessed By Feature Tracking Cardiac Magnetic Resonance Imaging

    Hitomi Kobayashi1, Yasuyuki Kobayashi2, Isamu Yokoe3, Akiyuki Kotoku4, Atsuma Nishiwaki5, Kaita Sugiyama6, Noboru Kitamura5 and Masami Takei5, 1Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 3Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, 4Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, 5Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 6Nihon University School of Medicine, Tokyo, Japan

    Background/Purpose: Cardiac involvements cause of morbidity and mortality globally in rheumatoid arthritis (RA). Myocardial disease is typically clinically silent, only manifesting as myocardial dysfunction after…
  • Abstract Number: 1348 • 2017 ACR/ARHP Annual Meeting

    Swollen Joint Count, but Not Inflammatory Cytokines, Differs By Frequency of Fish Consumption in a Cross-Sectional Rheumatoid Arthritis Cohort

    Sara K. Tedeschi1, Joan Bathon2, Jon T. Giles3, Tzu-Chieh Lin4, Kazuki Yoshida5 and Daniel Solomon1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 3Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Omega-3 fatty acids downregulate pro-inflammatory cytokines, thus have been of interest as adjunctive rheumatoid arthritis (RA) therapy for decades. We previously reported an inverse…
  • Abstract Number: 1613 • 2017 ACR/ARHP Annual Meeting

    Natural History of Disease Activity and Damage in Patients with Cutaneous Lupus Erythematosus on Standard of Care Treatments Using Longitudinal Registries from Two Academic Dermatology Centers

    Noelle M. Teske1, Khor Jia Ker2,3, Rui Feng4, Benjamin F. Chong1 and Victoria P Werth5, 1Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 2Dermatology, National Skin Centre, Singapore, Singapore, 3Dermatology, University of Pennsylvania, Philadelphia, PA, 4Department of Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania, Philadelphia, PA, 5University of Pennsylvania and the VA Medical Center, Philadelphia, PA

    Background/Purpose: The natural disease course of patients with cutaneous lupus erythematosus (CLE) on standard-of-care treatments is not fully characterized. We sought to characterize their disease…
  • Abstract Number: 1972 • 2017 ACR/ARHP Annual Meeting

    Causes of Death in 350 Patients with Systemic Autoimmune Rheumatic Diseases

    Juan Gabriel Ovalles-Bonilla1,2, Olaia Fernández-Berrizbeitia3, Julia Martínez-Barrio1, Larissa Valor1, Diana Hernández1, Iustina Janta1, Belen Serrano1, Claudia Saez1, Roberto Gonzalez1, María Correyero1, Leticia García1, Ana López-Cerón1, Alicia Silva1, Juan Carlos Nieto1, Carlos González1,4, Indalecio Monteagudo1 and Francisco Javier López Longo1,4, 1Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, 3Rheumatology, Hospital Universitario Basurto, Bilbao, Spain, 4Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

    Background/Purpose: The major SARD have an increased mortality compared to the general population. It is well known that the main causes of death in Systemic…
  • Abstract Number: 2456 • 2017 ACR/ARHP Annual Meeting

    Disease Flares Among Early Rheumatoid Arthritis Patients Treated with Continued Methotrexate Either Alone or in Combination with Adalimumab (Humira)

    Arthur Kavanaugh1, Ronald F van Vollenhoven2, Prashanth Sunkureddi3, Ying Zhang4, Jessica L. Suboticki5 and Josef S. Smolen6, 1Division of Rheumatology, Allergy, and Immunology, University of California San Diego, La Jolla, CA, 2Amsterdam Rheumatology and Immunology Center ARC, Amsterdam, Netherlands, 3University of Texas Medical Branch, Galveston, TX, 4AbbVie Inc., North Chicago, IL, 5AbbVie Inc., Mettawa, IL, 6Division of Rheumatology, Department of Medicine, Medical University of Vienna, and Hietzing Hospital, Vienna, Austria

    Background/Purpose : Some rheumatoid arthritis (RA) patients (pts) may experience flares in their disease even after reaching stable low disease activity (sLDA), but the consequences…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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