Abstracts tagged "Disease Activity"

Abstract Number: 999 • 2017 ACR/ARHP Annual Meeting
Association between Smoking with Spinal Level of Stiffness and Functional Limitation in Patients with Axial Spondyloarthritis: Results from the Spanish Atlas
Marco Garrido-Cumbrera¹, Victoria Navarro-Compán², Jorge Chacon-Garcia¹, Jordi Gratacos-Masmitja³, David Galvez-Ruiz¹, Eduardo Collantes Estevez⁴, Pedro Zarco⁵ and Olta Brace¹, ¹Universidad de Sevilla, Seville, Spain, ²Rheumatology, Hospital Universitario La Paz, Madrid, Spain, ³Rheumatology, Hospital Parc Taulí, Sabadell - Barcelona, Spain, ⁴Universidad de Cordoba, Cordova, Spain, ⁵H Fundación Alcorcón, Alcorcón, Spain
Background/Purpose: Smoking has been associated with greater disease activity and radiographic progression in patients with Axial Spondyloarthritis (ax-SpA). In addition, radiographic damage has been linked…
Abstract Number: 1388 • 2017 ACR/ARHP Annual Meeting
Fatigue Is Strongly Associated with the Patient Global Assessment and May Affect Disease Severity and Clinical Remission in Patients with Rheumatoid Arthritis: A Cross-Sectional Study from IORRA, a Large Observational Cohort of Japanese Rheumatoid Arthritis Patients
Naoki Sugimoto¹, Eiichi Tanaka¹, Eisuke Inoue^1,2, Kumiko Saka¹, Eri Sugano¹, Naohiro Sugitani¹, Moeko Ochiai¹, Yoko Shimizu¹, Rei Yamaguchi¹, Katsunori Ikari¹, Ayako Nakajima¹, Atsuo Taniguchi¹ and Hisashi Yamanaka¹, ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Fatigue is a common complaint in patients with rheumatoid arthritis (RA)1. However, its impact on disease activity and clinical remission in patients with RA…
Abstract Number: 1634 • 2017 ACR/ARHP Annual Meeting
Body Mass Index and Disease Activity in Systemic Lupus Erythematosus- a Paradoxical Relationship?
George Stojan¹, Wei Fu² and Michelle Petri³, ¹Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD
Background/Purpose: Obesity is more common in patients with SLE compared to the general population. The prevalence of obesity among SLE patients is between 28 and…
Abstract Number: 2153 • 2017 ACR/ARHP Annual Meeting
Decreased Lean Body Mass and Bone Mineral Density but Increased Body Fat in Myositis Patients Are Associated with Disease Duration, Inflammatory Status, Skeletal Muscle Involvement and Physical Activity
Sabina Oreska¹, Maja Spiritovic^1,2, Petr Cesak², Ondrej Marecek², Hana Storkanova¹, Katerina Kubinova¹, Martin Klein¹, Lucia Vernerova¹, Olga Ruzickova¹, Radim Becvar¹, Karel Pavelka¹, Ladislav Senolt¹, Herman F Mann¹, Jiri Vencovsky¹ and Michal Tomcik¹, ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Idiopathic inflammatory myopathies (IIM) are characterized by inflammation and atrophy of skeletal muscles, pulmonary and articular involvement, which limit the mobility/self-sufficiency of patients, and…
Abstract Number: 2508 • 2017 ACR/ARHP Annual Meeting
Obese Axial Spondyloarthropathy Patients Have Worse Disease Outcomes
Gillian Fitzgerald¹, Phil Gallagher², Catherine Sullivan³, Killian O Rourke⁴, Claire Sheehy⁵, Frances Stafford⁶, Carmel Silke⁷, Muhammad Haroon⁸, Ronan Mullan⁹, Sandy Fraser¹⁰, Grainne Murphy¹¹, Shawn Chavrimootoo¹², Oliver FitzGerald¹³ and Finbar O' Shea¹, ¹Rheumatology, St James's Hospital, Dublin 8, Ireland, ²St. Vincent's University Hospital, Department of Rheumatology, Dublin, Ireland, ³Rheumatology, UCHG Ireland, Galway, Ireland, ⁴Rheumatology, Midlands Regional Hospital, Tullamore, Co Offaly, Ireland, ⁵Rheumatology, University Hospital Waterford, Waterford, Ireland, ⁶Rheumatology, Blackrock Clinic, Co Dublin, Ireland, ⁷Rheumatology, Sligo University Hospital, Sligo, Ireland, ⁸Rheumatology, Kerry General Hospital, Co Kerry, Ireland, ⁹Department of Rheumatology, Tallaght Hospital, TCD, Dublin 24, Ireland, ¹⁰Department of Rheumatology, University Hospitals Limerick, Ireland, Limerick, Ireland, ¹¹Rheumatology, Cork University Hospital, Cork, Ireland, ¹²Rheumatology, Our Lady's Hospital, Co Meath, Ireland, ¹³St. Vincent's University Hospital, Department of Rheumatology. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
Background/Purpose: Obesity is a worldwide public health concern, due to its association with morbidity and mortality. Existing literature looking at obesity in axial spondyloarthropathy (axSpA)…
Abstract Number: 2862 • 2017 ACR/ARHP Annual Meeting
Diverse Disease Activity Measures Demonstrate That the Routine Assessment of Patient Index Data with 3 Measures (Rapid-3) Assesses Only Non Inflammatory Components of Disease and Should Not be Utilized in a Treat to Target Strategy in Rheumatoid Arthritis
Craig Wiesenhutter, Coeur d'Alene Arthritis Clinic, Coeur D Alene, ID
Background/Purpose: Treating Rheumatoid Arthritis (RA) patients to target (T2T) has been shown to result in better outcomes in patients with RA. Surrogate measures of disease…
Abstract Number: 471 • 2017 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Patients Resistant to Biologic Therapy, Are They Different?
Adeeba Al-Herz¹, Aqeel Ghanem², Khulood Saleh³, Adel Al-Awadhi⁴, Waleed Al-Kandari³, Eman Hasan⁵, Mohammad Hussain⁵, Ibrahim Nahar², Fatemah Abutiban⁶, Ahmad Alenizi⁶, Yaser Ali², Ali Aldei¹, Hebah Alhajeri², Sawsan Hayat², Ahmad Khadrawy³, Ammad Fazal³, Khaled Mokaddem¹, Agaz Zaman², Ghada Mazloum², Youssef Bartella¹, Sally Hamed¹, Ramia Alsouk⁶ and Ahmed Al-Saber⁷, ¹Rheumatology, Al-Amiri Hospital, Kuwait city, Kuwait, ²Rheumatology, Mubarak Al-Kabeer Hospital, Hawally, Kuwait, ³Rheumatology, Farwania Hospital, Farwania, Kuwait, ⁴Faculty of Medicine, Kuwait, Kuwait, ⁵Al-Amiri Hospital, Kuwait city, Kuwait, ⁶Rheumatology, Jahra Hospital, Jahra, Kuwait, ⁷Department of Mathematics, Kuwait Technical College, Kuwait city, Kuwait
Background/Purpose: Patients with rheumatoid arthritis (RA) may fail to respond to biologic therapy. We study patients who are resistant to different classes of biologic agents…
Abstract Number: 1039 • 2017 ACR/ARHP Annual Meeting
Influences for Therapeutic Changes in Rheumatoid Arthritis Patients from the Veterans Affairs Rheumatology Arthritis Registry Who Have Moderate to High Disease Activity
Brian Sauer¹, Jacob R. Stever¹, Chia-Chen Teng, MS¹, Neil Accortt², David Collier² and Grant Cannon¹, ¹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ²Amgen Inc., Thousand Oaks, CA
Background/Purpose: Current guidelines encourage the measurement of rheumatoid arthritis (RA) disease activity to achieve a low disease state (treat-to-target). Many RA patients with documented moderate…
Abstract Number: 1390 • 2017 ACR/ARHP Annual Meeting
Agreement between the DAS28-ESR and the DAS28-CRP and Factors Related to the Discrepancies between Disease Activity Levels According to These 2 Scores in Patients with Early Rheumatoid Arthritis
Cécile Gaujoux-Viala¹, Mohamed Belkacemi², Alain Cantagrel³, Bruno Fautrel⁴ and Bernard Combe⁵, ¹Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France, ²EA2415 Montpellier University, Montpellier, France, ³Rheumatology, Toulouse University Hospital and Toulouse University, Toulouse, France, ⁴UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, ⁵Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France
Background/Purpose: DAS28 is often used as a treatment decision tool in patients with rheumatoid arthritis (RA) in the daily clinic. Although different versions of DAS28…
Abstract Number: 1692 • 2017 ACR/ARHP Annual Meeting
Decreased Lean Body Mass, Body Fat and Bone Mineral Density in Scleroderma Patients Are Associated with Disease Activity and Physical Activity
Sabina Oreska¹, Maja Spiritovic^1,2, Petr Cesak², Michal Cesak², Hana Storkanova¹, Katerina Kubinova¹, Martin Klein¹, Lucia Vernerova¹, Olga Ruzickova¹, Herman F Mann³, Karel Pavelka¹, Ladislav Senolt¹, Jiri Vencovsky¹, Radim Becvar¹ and Michal Tomcik¹, ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, ³Experimental and Clinical Rheumatology, Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Systemic sclerosis (SSc) is characterized by fibrosis of the skin and visceral organs, especially digestive tract, and musculoskeletal involvement, which limit mobility/self-sufficiency of patients,…
Abstract Number: 2241 • 2017 ACR/ARHP Annual Meeting
Patterns and Outcomes on Disease Activity in Patients with Ankylosing Spondylitis (AS) Using Smart System of Disease Management (SSDM): Analysis of T2T Pattern Shift and Influential Factors
Jing Xue¹, Wenqiang Fan², Hua Wei³, Jing Yang⁴, Hui Song⁵, Hongbin Li⁶, Hongzhi Wang⁷, Xinwang Duan⁸, Zhenchun Zhang⁹, Jianlin Huang¹⁰, Yasong Li¹¹, Jian Ding¹², Xiaofei Shi¹³, Miaojia Zhang¹⁴, Zhenbiao Wu¹⁵, Cundong Mi¹⁶, Fei Xiao¹⁷, Hui Xiao¹⁷, Yuhua Jia¹⁷, Rui Bai¹⁷, Yan Bu¹⁷ and Huaxiang Wu¹⁸, ¹88 Jiefang Road, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China, ²Department of rheumatology, Central Hospital of XinXiang, Henan, XinXiang, China, ³No 98,Nantong West Rd,Yangzhou, Northern Jiangsu People's Hospital, Yangzhou, China, ⁴Department of rheumatology, Central Hospital of MianYang, Sichuan, Mian Yang, China, ⁵Beijing Jishuitan Hospital, Beijing, China, ⁶The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China, ⁷The First Hospital of Jiaxing, Jiaxing, China, ⁸Department of rheumatology, The Second Affiliated Hospital of Nanchang University, Nanchang, China, ⁹People's Hospital of Linyi, Shandong, Linyi, China, ¹⁰Department of rheumatology, The Sixth Hospital Affiliated to Sun yat-sen University, Guangzhou, China, ¹¹Zhejiang Provincal People's Hospital, Hangzhou, China, ¹²Ningbo City Medical Treatment Center Lihuili Hospital, Ningbo, China, ¹³The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China, ¹⁴Department of Rheumatology and Immunology, Jiangsu Province Hospital, Nanjing, China, ¹⁵The First Affiliated Hospital of The Fourth Military Medical University, Xi'an, China, ¹⁶The Second Affiliated Hospital of Guangxi Medical University, Nanning, China, ¹⁷Gothic Internet Technology Corporation, Shanghai, China, ¹⁸The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
Background/Purpose: This study is to evaluate pattern shifts and outcome trends of treat-to-target (T2T) under standard of care in ankylosing spondylitis (AS) patients with interactive…
Abstract Number: 2513 • 2017 ACR/ARHP Annual Meeting
The Effect of Alcohol on Disease Activity in Axial Spondyloarthritis
Sizheng Zhao^1,2, Daniel Thong³, Stephen Duffield¹, David Hughes³ and Nicola Goodson^1,2, ¹Musculoskeletal Biology 1 Department, University of Liverpool, Liverpool, United Kingdom, ²Aintree University Hospital, Liverpool, United Kingdom, ³University of Liverpool, Liverpool, United Kingdom
Background/Purpose: There has been much interest in smoking as a modifiable risk factor for increased disease severity in rheumatic diseases. However, the effects of alcohol…
Abstract Number: 2893 • 2017 ACR/ARHP Annual Meeting
The Use of Natural Language Processing to Identify, Retrieve, Report, and Correct Observational Data on US Veterans Enrolled in the Veterans Affairs Rheumatoid Arthritis Registry
Grant Cannon¹, Jorge Rojas¹, Neill Bell², Andreas Reimold³, Ted R. Mikuls⁴, Namrata Singh⁵, Gail S. Kerr⁶, Pascale Schwab⁷, Jennifer Barton⁷, Liron Caplan⁸, Joshua Baker⁹, Angelo L. Gaffo¹⁰, J. Steuart Richards¹¹, Deana Lazaro¹², Vikas Majithia¹³ and Brian Sauer¹, ¹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ²Salt Lake City VA Medical Center and University of Utah, Dallas VA Medical Center, Dallas, TX, ³Dallas VA Medical Center and University of Texas Southwestern, Dallas, TX, ⁴VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ⁵VA Nebraska-Western Iowa Health Care System and University of Iowa, Omaha, IA, ⁶Washington DC VA Medical Center, Georgetown and Howard University Hospitals, Washington, DC, ⁷Portland VA Medical Center and University of Oregon, Portland, OR, ⁸Denver VA Medical Center and Univerity of Colorado, Denver, CO, ⁹Philadelphia VA Medical Center and University of Pennsylvania, Philadelphia, PR, ¹⁰Birmingham VA Medical Center and University of Alabama at Birmingham, Birmingham, AL, ¹¹Pittsburgh VA Medical Center and University Of Pittsburgh, Pittsburgh, PA, ¹²Brooklyn VA Medical Center and SUNY Downstate, Brooklyn, NY, ¹³Jackson VA Medical Center and University of Mississippi, Jackson, MS
Background/Purpose: The Veterans Affairs (VA) Rheumatoid Arthritis (RA) (VARA) registry is an observational cohort study at 12 VA medical centers that prospectively collects clinical…
Abstract Number: 579 • 2017 ACR/ARHP Annual Meeting
Circulating MiR-145 As a Marker of Therapeutic Response to Anti-TNF Therapy in Patients with Ankylosing Spondylitis
Klára Prajzlerová¹, Veronika Hruskova¹, Martin Komarc², Šárka Forejtová¹, Karel Pavelka³, Jiri Vencovsky³, Ladislav Senolt³ and Maria Filkova¹, ¹Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Department of Anthropometrics and Methodology, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, ³Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: The altered expression of miRNAs contributes to the pathophysiology of inflammatory conditions. In addition, circulating miRNAs may serve as promising therapeutic and prognostic biomarkers.…
Abstract Number: 1065 • 2017 ACR/ARHP Annual Meeting
Mucosal-Associated Invariant T Cell Deficiency in Systemic Lupus Erythematosus Is Realted to an Intrinsic Defect in the Ca2+/Calcineurin/NFAT1 Signaling Pathway
Yong-Wook Park¹, Young-Nan Cho², Hye-Mi Jin¹, Tae-Jong Kim³ and Seung-Jung Kee⁴, ¹Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Korea, Republic of (South), ²Rheumatology, Chonnam National University Hospital and Medical School, Gwangju, MN, Korea, Republic of (South), ³Chonnam Nat`l University Medical School&Hospital, Chonnam, Korea, Republic of (South), ⁴Laboratory Medicine, Chonnam National University Medical School and Hospital, Gwangju, Korea, Republic of (South)
Background/Purpose: Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections and play an important role in mucosal immunity. However, the role of…

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