ACR Meeting Abstracts

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Abstracts tagged "Disease Activity"

  • Abstract Number: 1923 • 2018 ACR/ARHP Annual Meeting

    Treating Rheumatoid Arthritis to Target: Is Low Disease Activity Good Enough?

    Elena Nikiphorou1, Sam Norton2, Adam Young3, Lewis Carpenter2, Josh Dixey4, David Walsh5 and Patrick Kiely6, 1Academic Rheumatology, Department of Inflammation Biology, King's College London, London, Great Britain, 2Academic Rheumatology, King's College London, London, United Kingdom, 3University of Hertfordshire, Hertford, United Kingdom, 4Rheumatology, The Royal Wolverhampton, Wolverhampton, United Kingdom, 5Academic Rheumatology, University of Nottingham, Nottingham, Great Britain, 6Rheumatology Dept, St Georges Hospital, London, Great Britain

    Treating Rheumatoid Arthritis To Target: Is Low Disease Activity Good Enough? Background/Purpose:  It is now widely recognised that treat-to-target (T2T) principles in rheumatoid arthritis (RA)…
  • Abstract Number: 2484 • 2018 ACR/ARHP Annual Meeting

    Effect of Biologic Agents on Synovial Tissues from Patients with Rheumatoid Arthritis

    Ayako Kubota1, Toru Suguro1, Arata Nakajima2, Masato Sonobe3 and Kazuaki Tsuchiya1, 1Toho University Omori Medical Center, Tokyo, Japan, 2Orthopaedics, Toho University Sakura Medical Center, Sakura-city, Chiba, Japan, 3Toho University Sakura Medical Center, Chiba, Japan

    Background/Purpose: Multiple studies addressing the effects of biologics on the synovial tissue in rheumatoid arthritis (RA) patients have been reported. There are, however, few studies…
  • Abstract Number: 2785 • 2018 ACR/ARHP Annual Meeting

    Efficacy and Safety of Ustekinumab, an Interleukin-12/23 Inhibitor, in Patients with Active Systemic Lupus Erythematosus: 1-Year Results of a Phase 2, Randomized Placebo-Controlled, Crossover Study

    Ronald van Vollenhoven1, Bevra H Hahn2, George C Tsokos3, Carrie Wagner4, Peter Lipsky5, Benjamin Hsu4, Marc Chevrier4, Robert Gordon4, Kim Hung Lo4, Manon Triebel6, Kaiyin Fei4 and Shawn Rose4, 1Amsterdam Rheumatology and Immunology Center ARC, Amsterdam, Netherlands, 2University of California, Los Angeles, CA, 3Beth Israel Hospital, Boston, MA, 4Janssen Research & Development, LLC, Spring House, PA, 5AMPEL BioSolutions and RILITE Research Institute, Charlottesville, VA, 6Janssen Biologics Europe, Leiden, Netherlands

    Background/Purpose: Both the IL-12 and IL-23 pathways have been linked to SLE pathogenesis. The anti-IL-12/23 p40 monoclonal antibody ustekinumab (UST), which is approved for psoriasis,…
  • Abstract Number: 2986 • 2018 ACR/ARHP Annual Meeting

    The Impact of Exercise and Clinical Factors on Perceived Cognitive Function in Patients with Rheumatoid Arthritis: Results from a Prospective Cohort Study

    Nancy A. Shadick1, Christine K Iannaccone2, Patricia Katz3, Gabriela L. Maica4, Jonathan Coblyn5, Michael E Weinblatt6 and Jing Cui7, 1Rheumatology Immunology & Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Brigham and Women’s Hospital, Boston, MA, 3University of California San Francisco, San Francisco, CA, 4Department of Rheumatology, Allergy, and Immunology, Brigham and Women's Hospital, Boston, MA, 5Department of Rheumatology, Brigham & Womens Hospital, Boston, MA, 6Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 7Division of Medicine and Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Modifiable lifestyle factors such as inactivity and obesity contribute to cognitive decline in the general population, but little is known about how these factors…
  • Abstract Number: 328 • 2018 ACR/ARHP Annual Meeting

    Implementation of Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) Documentation in Systemic Lupus Erythematosus (SLE) Patients at an Academic Medical Center

    Sarah H. Chung1, Hsin-Hsuan Juo2, Jenna Thomason1 and Alison Bays3, 1Division of Rheumatology, University of Washington, Seattle, WA, 2rheumatology, University of Washington, seattle, WA, 3Rheumatology, University of Washington, Seattle, WA

    Background/Purpose: The 2008 European League Against Rheumatism (EULAR) Task Force on SLE management encourages the use of at least one of the SLE disease indices…
  • Abstract Number: 636 • 2018 ACR/ARHP Annual Meeting

    Remission/Low Disease Activity Is a Reasonable Treatment Target in Psa: Results from a Routine Care European Cohort of Psa Patients Treated with Ustekinumab or TNF Inhibitors

    Laure Gossec1,2, Paul Bergmans3, Kurt de Vlam4, Elisa Gremese5, Beatriz E. Joven6, Tatiana Korotaeva7, Michael Nurmohamed8,9, Petros Sfikakis10, Stefan Siebert11, Pavel Smirnov12, Elke Theander13 and Josef S. Smolen14, 1Rheumatology, Pitié Salpêtrière Hospital, Paris, France, 2Rheumatology, Sorbonne Université, Paris, France, 3Biometrics, Janssen-Cilag B.V., Breda, Netherlands, 4University Hospitals Leuven, Leuven, Belgium, 5Division of Rheumatology, Fondazione Policlinico Universitario A.Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy, 6Hospital Universitario 12 de Octubre, Madrid, Spain, 7Nasonova Research Institute of Rheumatology, Moscow, Russian Federation, 8Rheumatology, VU University Medical Center, Amsterdam, Netherlands, 9Amsterdam Rheumatology and Immunology Center | Reade, Amsterdam, Netherlands, 10Rheumatology Unit, 1st Dept. of Propaedeutic Internal Medicine, Joined Academic Rheumatology Program, Athens University Medical School, Athens, Greece, 11Institute of Infection, Immunity and Inflammation, University of Glasgow, Cardiff, United Kingdom, 12Biometrics, Janssen-Cilag B.V., Moscow, Russian Federation, 13Biometrics, Janssen-Cilag B.V., Solna, Sweden, 14Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria

    Background/Purpose: The link between treatment recommendations for PsA (to aim for a state of remission or low disease activity (LDA))1,2 and patient-important outcomes has been…
  • Abstract Number: 1460 • 2018 ACR/ARHP Annual Meeting

    Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis

    Brian J. Andonian1, Ching-Heng Chou2, Virginia B. Kraus2, William E. Kraus3 and Kim M. Huffman4, 1Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, 2Duke Molecular Physiology Institute, Duke University, Durham, NC, 3Medicine, Duke University, Durham, NC, 4School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC

    Background/Purpose: In rheumatoid arthritis (RA), sarcopenic obesity is associated with significant cardiometabolic disease and mortality. Biomarkers of disease activity in RA and obesity are complicated…
  • Abstract Number: 1674 • 2018 ACR/ARHP Annual Meeting

    Lupus Impact Tracker Validation in a Large European Spanish Lupus Registry Cohort

    Meenakshi Jolly1, Desiree R Azizoddin2, Iñigo Rúa-Figueroa3, Hervé Devilliers4, Raúl Menor Almagro5, Francisco Javier López Longo6, Juan Gabriel Ovalles-Bonilla7, Alejandro Olivé-Marqués8, Paula Rubio-Muñoz8, María Galindo9, Antonio Fernandez-Nebro10, Jaime Calvo-Alen11, Rosario García-Vicuña12, Eva Tomero13, Esther Uriarte Isacelaya14, Angela Pecondon-Español15, Ricardo Blanco16, Mercedes Freire17, Marian Gantes18, Monica Ibanez Barcelo19, Carlos Alberto Montilla-Morales20, José Rosas21, Jesús García-Villanueva22, Paloma Vela23, Esther Ruiz Lucea24, Francisco Toyos25, José Hernández Beiraín26, Elvira Diez Alvarez27, María Gema Bonilla Hernán28, Francisco Javier Narváez29, José Andréu-Sánchez30, Mireia Moreno-Martínez-Losa31, Ana Sánchez Atrio32, Maria Loreto Horcada33, Tatiana Cobo-Ibáñez34, Carlos Marras Fernandez-Cid35, Tomas Ramón Vazquez Rodriguez36, Eva Salgado-Pérez37, Vicente Torrente38, Juan Alegre-Sancho39, Coral Mouriño-Rodriguez40, Joel A. Block41 and JM Pego-Reigosa42, 1Rush University Medical Center, Chicago, IL, 2Department of Anesthesiology, Stanford University School of Medicine, Palo Alto, CA, 3Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, 4Department of Internal Medicine and Systemic Diseases, Hôpital François Mitterrand, CHU de Dijon, Dijon, France, 5Rheumatology, Hospital de Jerez de la Frontera, Jerez, Spain, 6Rheumatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 7Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, 8Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 9Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 10UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA) Hospital Regional Universitario de Málaga Departamento de Medicina y Dermatología, Universidad de Málaga, MÁLAGA, Spain, 11Rheumatology, Txagorritxu Hospital, Araba, Vitoria, Vitoria, Spain, 12Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 13HOSPITAL DE LA PRINCESA, spain, Spain, 14Rheumatology, Hospital Universitario de Donosti, San Sebastian, Spain, 15Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, 16Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 17Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo HospitalarioUniversitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 18Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, 19H. Son Llatzer, Palma de Mallorca, Spain, 20Hospital Clínico Universitario de Salamanca. Spain, Salamanca, Spain, 21Rheumatology, Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 22HOSPITAL RAMÓN Y CAJAL, Madrid, Spain, 23Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 24Rheumatology, Hospital de Basurto, Bilbao, Spain, 25Rheumatology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain, 26Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, 27Complejo Asistencial Universitario de León, León, Spain, 28Rheumatology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain, 29Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, 30HOSPITAL PUERTA DE HIERRO, Madrid, Spain, 31HOSPITAL PARC TAULÍ, Barcelona, Spain, 32University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology Department, Alcalá de Henares, Madrid, Spain, 33Rheumatology, Hospital de Navarra, Pamplona, Spain, 34Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, 35Rheumatology, Hospital Virgen de la Arrixaca, Murcia, Spain, 36Rheumatology, Hospital Universitario Lucus Augusti, Lugo, Spain, 37COMPLEJO HOSPITALARIO DE OURENSE, Ourense, Spain, 38Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain, 39HOSPITAL DR. PESET, València, Spain, 40Rheumatology, Rheumatology Section, Complexo Hospitalario Universitario de Vigo, Pontevedra, Spain, Vigo, Spain, 41Rheumatology, Rush University Medical Center, Chicago, IL, 42Complexo Hospitalario Universitario de Vigo, Vigo, Spain

    Background/Purpose: Lupus Impact Tracker (LIT) is a ten item unidimensional patient reported outcome tool developed from and for patients with systemic lupus erythematosus (SLE). It…
  • Abstract Number: 1930 • 2018 ACR/ARHP Annual Meeting

    Histologic and Transcriptional Evidence of Subclinical Synovial Inflammation in Rheumatoid Arthritis Patients in Clinical Remission

    Dana Orange1, Phaedra Agius2, Edward F. DiCarlo3, Serene Z. Mirza4, Cristina Rozo5, Tania Pannellini5, Mark P. Figgie6, William H. Robinson7, Jackie Szymonifka5, Vivian P. Bykerk5, Laura T. Donlin8 and Susan M. Goodman5, 1Rockefeller University, New York, NY, 2New York Genome Center, New York, NY, 3Laboratory Medicine, Hospital for Special Surgery, New York, NY, 4Rheumatology, Hospital for Special Surgery, New York, NY, 5Hospital for Special Surgery, New York, NY, 6Surgery, Hospital for Special Surgery, New York, NY, 7Stanford University, Palo Alto, CA, 8Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY

    Background/Purpose:   Rheumatoid Arthritis (RA) patients in clinical remission may still develop structural damage that has been attributed to ongoing synovial inflammation, sometimes only detectable…
  • Abstract Number: 2488 • 2018 ACR/ARHP Annual Meeting

    Characteristics of Difficult-to-Treat Rheumatoid Arthritis: Results of an International Survey

    Nadia MT Roodenrijs1, Maria JH de Hair1, Marlies C van der Goes1, Johannes W. G. Jacobs1, Paco MJ Welsing1, Désirée van der Heijde2, Daniel Aletaha3, Maxime Dougados4, Kimme L. Hyrich5, Iain B. McInnes6, Ulf Müller-Ladner7, Ladislav Šenolt8, Zoltan Szekanecz9, Jacob van Laar1 and Gyorgy Nagy10, 1Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Utrecht, Netherlands, 2Leiden University Medical Centre, Leiden, Netherlands, 3Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 4Department of Rheumatology, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris Descartes University, Paris, France, Paris, France, 5Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, 6Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK, Glasgow, United Kingdom, 7Dept. of Rheumatology and Clinical Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Germany, Bad Nauheim, Germany, 8First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 9Department of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, Debrecen, Hungary, 10Department of Genetics, Cell- and Immunobiology & Department of Rheumatology, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary, Budapest, Hungary

    Background/Purpose: EULAR and ACR recommendations on the management of rheumatoid arthritis (RA) mainly focus on early RA and medication.1,2 Following these recommendations, several patients nevertheless…
  • Abstract Number: 2827 • 2018 ACR/ARHP Annual Meeting

    Remission Targets and Prevention of Subclinical Atherosclerosis in Psoriatic Arthritis- Which Target Should We Choose?

    Isaac T. Cheng1, Qing Shang2, Edmund Kwok Ming Li2, Priscilla Wong1, Lydia Ho Pui Tam2, Tracy Y. Zhu3, M Mimi Chang4, JW Jack LEE5, PW Alex Lee2 and Lai-Shan Tam4, 1Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, Hong Kong, China, 2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 3Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, 4Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 5Biostatistics Division, School of Public and Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: Systemic inflammation contributes to the excess risk of cardiovascular disease (CVD) in PsA. We had demonstrated that achieving sustained minimal disease activity (sMDA) was…
  • Abstract Number: 381 • 2018 ACR/ARHP Annual Meeting

    Muscle Endurance Deficits in Myositis Patients Despite Normal Manual Muscle Testing Scores

    David Amici1,2, Iago Pinal-Fernandez3,4, Ruben Pagkatipunan5, Albert Mears5, Rebecca De Lorenzo6, Eleni Tiniakou7, Jemima Albayda3, Julie J. Paik7, Thomas E. Lloyd8, Lisa Christopher-Stine9, Andrew Mammen8,10 and Tae Chung11, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 4Muscle Diseases Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases. National Institutes of Health, Bethesda, MD, 5Johns Hopkins University School of Medicine, Baltimore, MD, 6Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 7Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 8Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 9Medicine and Neurology, Johns Hopkins University, Baltimore, MD, 10National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 11Johns Hopkins University, Baltimore, MD

    Background/Purpose: To assess muscle function in myositis patients, clinicians typically use manual muscle testing (MMT), a measure of maximal isometric strength. However, patients with high…
  • Abstract Number: 637 • 2018 ACR/ARHP Annual Meeting

    How to Define Remission and Low Disease Activity in Psoriatic Arthritis? an Analysis of 419 Patients with a Double Perspective, Based on Composite Scores and Patients’ and Physicians’ Perspectives

    Clémence Gorlier1, Deborah Puyraimond-Zemmour1, Laura C. Coates2, Ana-Maria Orbai3, Uta Kiltz4, Ying Ying Leung5, Penelope Palominos6, Juan D. Cañete7, Rossana Scrivo8, Andra Rodica Balanescu9, Emmanuelle Dernis10, Sandra Tälli11, Adeline Ruyssen-Witrand12, Martin Soubrier13, Sibel Zehra Aydın14, Lihi Eder15, Inna Gaydukova16, Ennio Lubrano17, Pascal Richette18, M. Elaine Husni19, Maarten de Wit20, Josef S. Smolen21 and Laure Gossec22, 1Sorbonne Université, PARIS, France, 2University of Oxford, Oxford, United Kingdom, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Rheumazentrum Ruhrgebiet, Herne, Germany, 5Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, 6Rheumatology, Hospital de Clinicas de Porto Alegre, Santa Cecilia, Brazil, 7Rheumatology, Hospital Clinic and IDIBAPS, Barcelona, Spain, 8Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, 9Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, 10Service de Rhumatologie, CH du Mans, Le Mans, France, 11East-Tallinn Central Hospital, Department of Rheumatology, Tallinn, Estonia, 12Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, 13Rheumatology, Department of Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, 14University of Ottawa, Ottawa, ON, Canada, 15Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada, 16North-western state medical university n.a. II Mechnikov, St. Petersburg, Russian Federation, 17Department of Medicine and Health Sciences Vincenzo Tiberio, University of Molise, Campobasso, Italy, 18Lariboisière Hospital, Lariboisière, University of Paris 7, Paris, France, 19Orthopedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, 20Dept. Medical Humanities, Amsterdam Public Health (APH), VU University Medical Centre, Amsterdam, Netherlands, 21Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria, 22Sorbonne Universités, Paris, France

    Background/Purpose: Remission (REM) or minimal/low disease activity (LDA) is the treatment goal in Psoriatic Arthritis (PsA). There is no consensus on definitions of REM/LDA. Recently,…
  • Abstract Number: 1462 • 2018 ACR/ARHP Annual Meeting

    Fibrin Deposition and Neutrophil Infiltration of Rheumatoid Arthritis Synovium Are Associated with Duration of Morning Stiffness

    Dana Orange1, Caroline Jiang1, Edward F. DiCarlo2, Tania Pannellini3, Laura T. Donlin4, Serene Z. Mirza5, Mark P. Figgie6, Vivian P. Bykerk7, Ana-Maria Orbai8, Sarah Mackie9 and Susan M. Goodman3, 1Rockefeller University, New York, NY, 2Laboratory Medicine, Hospital for Special Surgery, New York, NY, 3Hospital for Special Surgery, New York, NY, 4Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 5Rheumatology, Hospital for Special Surgery, New York, NY, 6Surgery, Hospital for Special Surgery, New York, NY, 7Deptartment of Rheumatology, Hospital for Special Surgery, New York, NY, 8Johns Hopkins University School of Medicine, Baltimore, MD, 9NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Stiffness is a hallmark of RA, but little is known about the etiology. We investigated stiffness association with RA disease activity and determined whether…
  • Abstract Number: 1675 • 2018 ACR/ARHP Annual Meeting

    Lupus Impact Tracker Responds to Changes in Low Disease Activity and Remission Outcomes in a Large Spanish Lupus Registry Cohort

    Meenakshi Jolly1, Hervé Devilliers2, Iñigo Rúa-Figueroa3, Desiree R Azizoddin4, Raúl Menor Almagro5, Francisco Javier López Longo6, Juan Gabriel Ovalles-Bonilla7, Alejandro Olivé-Marques8, Paula Rubio-Muñoz8, María Galindo-Izquierdo9, Antonio Fernandez-Nebro10, Jaime Calvo-Alen11, Txaro García de Vicuña-Pinedo12, Eva G Tomero-Muriel13, Esther Uriarte Isacelaya14, Angela Pecondon-Español15, Mercedes Freire-González16, Ricardo Blanco17, Marian Gantes Mora18, Monica Ibanez Barcelo19, Carlos Alberto Montilla-Morales20, José José C Rosas-Gómez de Salazar21, Jesús García-Villanueva22, Paloma Vela-Casasempere23, María E Ruiz-Lucea24, Francisco J Toyos-Sáenz-de-Miera25, José Hernández Beiraín26, Elvira Diez Alvarez27, Gema Bonilla-Hernán28, Javier Narváez-García29, José Andréu-Sánchez30, Mireia Moreno-Martínez-Losa31, Ana Sánchez Atrio32, Maria Loreto Horcada33, Tatiana Cobo-Ibáñez34, Carlos Marras Fernandez-Cid35, Tomas Ramón Vazquez Rodriguez36, Eva Salgado-Pérez37, Vicente Torrente38, Juan Alegre-Sancho39, Coral Mouriño-Rodriguez40, Joel A. Block1 and JM Pego-Reigosa41, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2de médecine Interne, Hôpital Universitaire Dijon, Dijon, France, 3Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, 4Department of Anesthesiology, Stanford University School of Medicine, Palo Alto, CA, 5Rheumatology, Hospital de Jerez de la Frontera, Jerez, Spain, 6Rheumatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 7Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, 8Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 9Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 10UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA) Hospital Regional Universitario de Málaga Departamento de Medicina y Dermatología, Universidad de Málaga, MÁLAGA, Spain, 11Rheumatology, Txagorritxu Hospital, Araba, Vitoria, Vitoria, Spain, 12Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 13Rheumatology, Hospital de La Princesa. Madrid. Spain, Madrid, Spain, 14Rheumatology, Hospital Universitario de Donosti, San Sebastian, Spain, 15Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, 16Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo HospitalarioUniversitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 17Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 18Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, 19H. Son Llatzer, Palma de Mallorca, Spain, 20Hospital Clínico Universitario de Salamanca. Spain, Salamanca, Spain, 21Rheumatology, Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 22HOSPITAL RAMÓN Y CAJAL, Madrid, Spain, 23Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 24Rheumatology, Hospital de Basurto, Bilbao, Spain, 25Rheumatology, Hospital Universitario Virgen de la Macarena, Sevilla, Spain, 26Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, 27Complejo Asistencial Universitario de León, León, Spain, 28Rheumatology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain, 29Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, 30HOSPITAL PUERTA DE HIERRO, Madrid, Spain, 31HOSPITAL PARC TAULÍ, Barcelona, Spain, 32University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology Department, Alcalá de Henares, Madrid, Spain, 33Rheumatology, Hospital de Navarra, Pamplona, Spain, 34Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, 35Rheumatology, Hospital Virgen de la Arrixaca, Murcia, Spain, 36Rheumatology, Hospital Universitario Lucus Augusti, Lugo, Spain, 37COMPLEJO HOSPITALARIO DE OURENSE, Ourense, Spain, 38Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain, 39HOSPITAL DR. PESET, València, Spain, 40Rheumatology, Rheumatology Section, Complexo Hospitalario Universitario de Vigo, Pontevedra, Spain, Vigo, Spain, 41Complexo Hospitalario Universitario de Vigo, Vigo, Spain

    Background/Purpose: Remission & Low Disease activity state (LDAS) are the two new health outcome measures developed with “treat to target” strategy in mind for Systemic…
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