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Abstracts tagged "Disease Activity"

  • Abstract Number: 0648 • ACR Convergence 2025

    Real World Comparative Use of Anifrolumab in Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus: A Multicenter Cohort Study

    Rajaie Namas1, Sarah Al Qassimi2, Rowaida Abdou3, Jawahir Alameri2, Reem Alblooshi4, Fatima Abdulla4, Muriel Ghosn4, Amir Malik4, Raghda Almaashari4, Fulvio Salvo4, Mohamed Abuzakouk4, Atheer Al Ansari5, Hazem Helmy Ali Rifaai5, Ahlam Almarzooqi6, Asia Mubashir7, Ahmed Aldhaheri4, Suzan Attar8 and Mohamed Elarabi9, 1Cleveland Clinic Abu Dhabi, Detroit, MI, 2Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 3NMC Specialty Hospital Abu Dhabi, Abu Dhabi, United Arab Emirates, 4Cleveland Clinic Abu Dhabi, Abu Dhabi, 5Mediclinic, Abu Dhabi, United Arab Emirates, 6Emirates Health Services, Sharjah, United Arab Emirates, 7Cleveland Clinic, Abu Dhabi, Abu Dhabi, United Arab Emirates, 8King Abdulaziz University, Saudi Arabia, Jeddah, Saudi Arabia, 9Cleveland Clinic Abu Dhabi, Hannon, ON, Canada

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiorgan organ damage, and early mortality. Anifrolumab (ANI), a human monoclonal antibody targeting the…
  • Abstract Number: 0495 • ACR Convergence 2025

    Effectiveness and Safety of Iguratimod with Background Methotrexate Therapy in Indian Patients with Rheumatoid Arthritis: A Randomized Double Blinded Placebo Controlled Study

    MIDHUN SAKRAVARTHY JALANATHAN1, Mehdi Ali Mirza1, Vijaya prasanna Parimi2, Seethalakshmi S1 and Tejaswini Ramineni3, 1ESIC Medical College and Hospital, Sanathanagar, Hyderabad, Telangana, India, 2ESIC Medical College and Super Specilaity Hospital, hyderabad, Telangana, India, 3Esic Medical College And Hospital, Sanathnagar, Hyderabad, Telangana, India

    Background/Purpose: Iguratimod (IGU), an oral synthetic disease-modifying antirheumatic drug (DMARD), has shown significant efficacy and safety in rheumatoid arthritis (RA) when combined with methotrexate (MTX)…
  • Abstract Number: 0409 • ACR Convergence 2025

    Discordance Between Disease Activity and Patient-Reported Outcomes in Patients with Juvenile Idiopathic Arthritis

    Julia Harris1, Leslie Favier2, Emily Fox3, Jordan Jones2, Michael Holland3, Cara Hoffart2, Maria Ibarra3 and Ashley Cooper2, 1Children's Mercy Kansas City, Overland Park, KS, 2Children's Mercy Kansas City, Kansas City, MO, 3Children's Mercy Hospital, Kansas City, MO

    Background/Purpose: Outcome assessment is essential to optimize care for patients with juvenile idiopathic arthritis (JIA). Although disease activity and patient-reported outcomes (PROs) are different measures,…
  • Abstract Number: 1509 • ACR Convergence 2025

    Outcome of Newly Diagnosed SLE with Serositis and Its Clinical Features in Daily Clinical Practice: A Single Center Study

    Shuzo Sato, Kaito Moriuchi, So Yamamoto, Hiroki Nibu, Takahito Sakamoto, Shotaro Ogawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Haruki Matsumoto, Jumpei Temmoku and Tomoyuki Asano, Fukushima Medical University, Fukushima, Fukushima, Japan

    Background/Purpose: Past reports have shown that serositis is a risk factor for organ damage in patients with SLE. However, the distinct clinical features of newly…
  • Abstract Number: 2703 • ACR Convergence 2025

    Longitudinal Changes on Cranial Magnetic Resonance Imaging in Relapsing Giant Cell Arteritis

    Ruoheng Zeng1, Ryan Rebello2, Konstanze Guggenberger3, Joshua Baker4, Shubhasree Banerjee4, Robert Kurtz4, Naomi Amudala4, Peter Merkel4 and Rennie Rhee4, 1University of Pennsylvania School of Medicine, Philadelphia, PA, 2St. Joseph’s Hospital at McMaster University, Hamilton, ON, Canada, 3University Hospital of Wuerzburg, Wuerzburg, Germany, 4University of Pennsylvania, Philadelphia, PA

    Background/Purpose: There is a need for better tools to monitor disease activity in giant cell arteritis (GCA). Prior studies demonstrated that vascular enhancement on cranial…
  • Abstract Number: 2404 • ACR Convergence 2025

    Clinical features of Elderly-onset Systemic Lupus Erythematosus

    Jessica Dai1, Erin Carter2, Mala Masson3, Amit Saxena4, H Michael Belmont5, Peter Izmirly6 and Jill Buyon4, 1New York University Grossman School of Medicine, Tenafly, NJ, 2New York University Grossman School of Medicine, New York, NY, 3NYU Langone Medical Center- Division of Rheumatology, New York, NY, 4NYU Grossman School of Medicine, New York, NY, 5NYU School of Medicine, New York, NY, 6New York University Grossman School of Medicine, New York, NY

    Background/Purpose: Systemic lupus erythematosus (SLE) is a multisystemic chronic disease characterized by a wide range of clinical and serological manifestations. It most commonly affects young…
  • Abstract Number: 2246 • ACR Convergence 2025

    Different Populations, Different SDAI Cut-Off? A Proposal for a New Remission Threshold in Brazilian RA Patients from a National Multicenter Study

    Lucas Pires1, Alisson Pugliesi1, Cleandro Pires2, Ana Carolina Hidaka3, Vitor Cruz4, Manoel Barros Bertolo1, Ana Paula Reis5, Rina Dalva Neubarth Giorgi6, Leticia Pereira7, Sebastião Cezar Radominski8, Ivanio Alves Pereira9, Maria Fernanda Brandão de Resende Guimarães10, Paulo Louzada Junior11, Maria de Fátima Lobato da Cunha Sauma12, Karina Bonfiglioli13, Claiton Viegas Brenol14, Licia Maria Henrique da Mota2 and Geraldo da Rocha Castelar Pinheiro7, 1Unicamp, Campinas, Brazil, 2UNB, Brasilia, Distrito Federal, Brazil, 3UNB, Brasilia, Brazil, 4UFG, Goias, Brazil, 5UniCEUB, Brasilia, Brazil, 6IAMSPE, São Paulo, Brazil, 7UERJ, Rio de Janeiro, Brazil, 8UFPR, Curitiba, Brazil, 9UFSC, Florianopolis, Brazil, 10UFMG, Belo Horizonte, Brazil, 11USP-RP, Ribeirão Preto, Brazil, 12UFPA, Belem, Brazil, 13USP-SP, São Paulo, Brazil, 14UFRGS, Porto Alegre, Brazil

    Background/Purpose: Remission criteria in Rheumatoid Arthritis (RA) have continuously evolved to balance the risks of both overtreatment and undertreatment. The most recent update includes the…
  • Abstract Number: 1661 • ACR Convergence 2025

    Artificial Intelligence applied to Patient Reported Outcomes and Passive Physiologic Sensor Data can Accurately Classify Low Disease Activity in Rheumatoid Arthritis Patients

    Jeffrey Curtis1, Yujie Su2, sam Barskiy3, Emily Holladay3, Shilpa Venkatachalam4, David Curtis5, Tapan Mehta3 and Fenglong Xie6, 1Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, 2Foundation for Advancing Science, Technology, Education and Research (FASTER), Hoover, AL, 3University of Alabama at Birmingham, Birmingham, AL, 4Global Healthy Living Foundation, New York, NY, 5Global Healthy Living Foundation, Meriden, 6The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Remote therapeutic monitoring (RTM) and remote physiologic monitoring (RPM) programs have the potential to capture data between clinical visits and provide information back to…
  • Abstract Number: 1430 • ACR Convergence 2025

    Redefining BASDAI cut-offs: implications for patients’ eligibility for initiating biologic disease-modifying antirheumatic treatment in axial spondyloarthritis

    Stylianos Georgiadis1, Lykke Ørnbjerg1, Brigitte Michelsen2, Tore K. Kvien2, Mehrdad Shoae Kazemi1, Bente Glintborg1, Anne Gitte Loft3, Rita Fonseca4, Helena Santos5, Andreas Reich6, Anne C. Regierer6, Jarno Rutanen7, Laura Kuusalo8, Gary Macfarlane9, Gareth T. Jones9, Adrian Ciurea10, Michael J. Nissen11, Bjorn Gudbjornsson12, Olafur Palsson13, Ziga Rotar14, Katja Perdan Pirkmajer15, Daniela Di Giuseppe16, Merete Hetland17 and Mikkel Ostergaard18, 1Rigshospitalet, Glostrup, Denmark, 2Diakonhjemmet Hospital, Oslo, Norway, 3Aarhus University Hospital, Aarhus, Denmark, 4Unidade Local de Saúde de Entre Douro e Vouga, Santa Maria da Feira, Portugal, 5Instituto Português de Reumatologia, Lisbon, Portugal, 6German Rheumatology Research Center, Berlin, Germany, 7Tampere University Hospital, Tampere, Finland, 8Turku University Hospital, Turku, Finland, 9University of Aberdeen, Aberdeen, United Kingdom, 10University Hospital Zurich, Zurich, Switzerland, 11Geneva University Hospital, Geneva, Switzerland, 12Landspitali University Hospital; Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 13University of Iceland, Reykjavik, Iceland, 14University Medical Centre Ljubljana, Ziri, Slovenia, 15University Medical Centre Ljubljana, Ljubljana, Slovenia, 16Karolinska Institutet, Department of Medicine Solna, Clinical Epidemiology Division, Stockholm, Stockholms Lan, Sweden, 17Copenhagen Center for Arthritis Research (COPECARE) and DANBIO, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup; Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, 18Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, and Copenhagen Center for Arthritis Research, Center for Rheumatology, Rigshospitalet, Glostrup, Denmark

    Background/Purpose: In patients with axial spondyloarthritis (axSpA), high disease activity is a key indication for biological disease-modifying antirheumatic drug (bDMARD) initiation. The Axial Spondyloarthritis Disease…
  • Abstract Number: 1310 • ACR Convergence 2025

    Naturalized Language Processing Based Extraction of Rheumatoid Arthritis Disease Activity Measures from the Electronic Health Record

    Elizabeth Park1, Iram Kamdar2, Reid Weisberg1, Andy Nguyen1, Joan Bathon3, Jon Giles4, Chunhua Weng5 and Elana Bernstein1, 1Columbia University Irving Medical Center, New York, NY, 2Columbia University Data Science Institute, New York, NY, 3Columbia University, NEW YORK, NY, 4Cedars-Sinai Medical Center, New York, NY, 5Columbia University Department of Biomedical Informatics, New York, NY

    Background/Purpose: A treat-to-target approach in rheumatoid arthritis (RA) requires intense monitoring of RA disease activity with measures such as the clinical disease activity index (CDAI).…
  • Abstract Number: 0620 • ACR Convergence 2025

    The usefulness of neutrophil-to-lymphocyte ratio as a biomarker to predict lupus flares in patients under remission

    Luis Daniel Fajardo Hermosillo and María Karina Lizbeth López Ramírez, Unidad Médica de Alta Especialidad, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, GUADALAJARA, Jalisco, Mexico

    Background/Purpose: Remission in Systemic Lupus Erythematosus (SLE) is described by the Definition of Remission in SLE (DORIS), but it is hardly achieved in clinical practice,…
  • Abstract Number: 0493 • ACR Convergence 2025

    Phase I Trial in Participants with Rheumatoid Arthritis and Healthy Volunteers with CIT-013, a First in Class NETosis Inhibitor

    Maarten Kraan1, Salah Hadi2, Leonie Middelink3, Renato Chirivi3, Eric meldrum3, Naomi Klarenbeek4 and Patrick Round3, 1Citryll BV, Den Dolder, Netherlands, 2ICON Netherlands BV, Groningen, Netherlands, 3Citryll BV, Oss, Netherlands, 4CHDR, Leiden, Netherlands

    Background/Purpose: Aberrant Neutrophil Extracellular Trap (NET) production contributes to the pathophysiology of multiple inflammatory and autoimmune diseases including rheumatoid arthritis (RA). We report data of…
  • Abstract Number: 0391 • ACR Convergence 2025

    Which score fits best? Correlation of clinical indices of Disease Activity and Ultrasound findings in Juvenile Idiopathic Arthritis during Transitional Care

    Andrea Pilato1, Giusyda Tarantino2, Maria Isabella Petrone2, Angela Aquilani2, Emiliano Marasco2, Rebecca Nicolai2, Fabrizio De Benedetti3, Roberto Giacomelli4, Luca Navarini1 and Silvia Magni-Manzoni2, 1University of Rome Campus Bio-Medico, Rome, Italy, 2Bambino Gesù IRCCS Children's Hospital, Rome, Italy, 3Bambino Gesu Children's Hospital, Rome, Rome, Italy, 4i) Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico; ii) Rheumatology and Clinical Immunology, Department of Medicine, School of Medicine, University of Rome "Campus Bio-Medico", Rome, Italy

    Background/Purpose: Monitoring disease activity is a crucial aspect of the treat to target paradigm in the management of rheumatic diseases. There are no standardized protocols…
  • Abstract Number: 2686 • ACR Convergence 2025

    Impact of autoimmunity, disease activity and treatment on the time course of bone density, microstructure and biomechanics in inflammatory arthritis.

    Koray Tascilar1, Alp Temiz1, Filippo Fagni2, Arnd Kleyer3, Louis Schuster1, Stephan Kemenes1, Sara Bayat1, David Simon4 and Georg Schett5, 1Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany, 2Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Bayern, Germany, 3Charite Universitätsmedizin Berlin, Erlangen, Bayern, Germany, 4Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Germany, 5Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany

    Background/Purpose: RA and PsA follow different pathomechanisms and incur disease-specific erosive and osteoproliferative bone changes. We used data from a large cohort of RA and…
  • Abstract Number: 2366 • ACR Convergence 2025

    Association Between Skin and Joint Symptom Control and Patient-Reported Pain and Health Status Among Patients with Psoriatic Arthritis in the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry Initiating Biologic or Targeted Synthetic Disease-Modifying Antirheumatic Drugs

    Philip J. Mease1, Nicole Middaugh2, Yolanda Muñoz Maldonado2, Chao Song3, Skyler Peterson4, Robert Low3 and Alexis Ogdie5, 1Department of Rheumatology, Providence-Swedish Medical Center and University of Washington, Seattle, WA, 2CorEvitas, LLC, Waltham, MA, 3UCB, Smyrna, GA, 4CorEvitas, LLC, Waltham, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic inflammatory condition primarily affecting the joints and skin.1 More severe symptoms are associated with lower health-related quality of…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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