Abstracts tagged "diagnosis"

Abstract Number: 134 • 2020 Pediatric Rheumatology Symposium
Evaluation of Self-report Screening Measures in the Detection of Depressive and Anxiety Disorders Among Children and Adolescents with Systemic Lupus Erythematosus
Michelle Quilter¹, Katherine Cost ², Reva Schachter ³, Julie Couture ⁴, Ashley Danguecan ⁵, Lawrence Ng ⁶, Daniela Dominguez ⁶, Linda Hiraki ⁷, Deborah Levy ⁸, Earl D. Silverman ⁹, Kate Neufeld ¹⁰, Andrea Knight ¹¹ and Daphne Korczak ², ¹Dept. of Psychiatry, Hospital for Sick Children, Dept. of Psychiatry, University of Toronto, Toronto, Ontario, Canada, ²Dept. of Psychiatry, Hospital for Sick Children, Dept. of Psychiatry, University of Toronto, Toronto, Canada, ³Dept. of Psychiatry, Hospital for Sick Children,, Toronto, Canada, ⁴Division of Pediatric Rheumatology-Immunology, CHU Sainte-Justine, Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada, ⁵Hospital for Sick Children, Toronto, Canada, ⁶Division of Rheumatology, The Hospital for Sick Children, Toronto, Canada, ⁷Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Canada, ⁹Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Canada, ¹⁰University of Toronto, The Hospital for Sick Children, Toronto, Canada, ¹¹SickKids Research Institute, Toronto, Canada
Background/Purpose: Screening for co-morbid psychiatric disorder is of high clinical importance in childhood-onset systemic lupus erythematosus (cSLE). However, there are no validated screening measures for…
Abstract Number: 465 • 2019 ACR/ARP Annual Meeting
Prognostic Factors and Clinical Outcome Modifiers in Patients with Rheumatoid Arthritis: A Review
Leticia Ferri¹, Grace Crocket ², Xue Han ¹, Boris Breznen ³ and Mir Sohail Fazeli ³, ¹Bristol-Myers Squibb Company, Princeton, NJ, ²Bristol-Myers Squibb; Rutgers University, New York City, NY, ³Doctor Evidence, Santa Monica, CA
Background/Purpose: The current goal in treatment of RA is to deliver therapies tailored to individual patients’ characteristics. Establishing disease prognosis is a crucial first step…
Abstract Number: 488 • 2019 ACR/ARP Annual Meeting
Citrullinated Antigens with Multiple Citruline Similar Motif Could Be Used for RA Diagnosis
zhiwei ru ¹, Xuedong Chen ², Xiaoyan huang ¹, Jianrong Lou ¹, YongZheng peng ³ and Xiang Yang¹, ¹Leide bioscience Inc, guang zhou, Guangdong, China (People's Republic), ²Southern Medicine University, guang zhou, Guangdong, China (People's Republic), ³Southern Medicine University, guang dong, Guangdong, China (People's Republic)
Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint inflammation that ultimately leads to joint destruction. Diagnosis of RA is important…
Abstract Number: 2074 • 2019 ACR/ARP Annual Meeting
Automated Diagnosis Extraction from Electronic Medical Records with Machine Learning Classifiers
Tjardo Maarseveen¹, Thomas Huizinga ¹, Marcel J.T. Reinders ¹, Erik van den Akker ¹ and Rachel Knevel ¹, ¹Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The use of Electronic Medical Records (EMR) for research purposes has led to an increasing interest in Natural Language Processing (NLP) for text classification.…
Abstract Number: 2655 • 2019 ACR/ARP Annual Meeting
Large Vessel Vasculitis: Diagnosis Is Very Frequent with Ultrasound Examination and Shows Responsiveness to Treatment
Eugenio de Miguel¹, Irene Monjo ², Elisa Fernández ³, Diana Peiteado ⁴, Chamaida Plasencia ⁵ and Alejandro Balsa ⁵, ¹Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ²FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, Spain, ³Rheumatology Department, La Paz University Hospital, Madrid, Madrid, Spain, ⁴Hospital Universitario La Paz, Madrid, ⁵Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain
Background/Purpose: Giant cell arteritis (GCA) is the most common systemic vasculitis in the elderly. In the EULAR recommendations of 2018 for the use of imaging…
Abstract Number: 2763 • 2019 ACR/ARP Annual Meeting
What Disease Do You Have? – Assessment and Predictors of Accurate Illness Naming in Rheumatology
Jacob Meindertsma¹, Kara Harrison ¹, Nicholas Lucchesi ¹ and Adam Carlson ¹, ¹University of Virginia, Charlottesville, VA
Background/Purpose: Shared decision making remains central to the effective treatment of many rheumatologic conditions and is most appropriate when the patient and physician agree on…
Abstract Number: 793 • 2018 ACR/ARHP Annual Meeting
Clinical Associations of Anti-U11/U12 (RNPC-3) Autoantibodies in Patients with Systemic Sclerosis
Lorenzo Beretta¹, Michael Mahler², Chelsea Bentow², Andrea Seaman², Fabrece Roup², Michelle Amio², Karl Norvell², Jay Milo², Susan Encabo², Janire Perurena³, Maite Sanz³, Alfredo Guillen⁴, Ana Marín³, Vicent Fonollosa³, Eduardo Callejas³ and Carmen Pilar Simeón⁴, ¹Scleroderma Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy, ²Research and Development, Inova Diagnostics, San Diego, CA, ³Scleroderma Unit, Internal Medicine Department, Vall d’Hebron Hospital, Barcelona, Spain, ⁴Scleroderma Unit, Internal Medicine Department, Vall d’Hebron Hospital, Barcelona, Spain
Background/Purpose: Anti-nuclear antibodies (ANA) are present in approximately 90% of sera from systemic sclerosis (SSc) patients and play an important role in the diagnosis and…
Abstract Number: 2804 • 2018 ACR/ARHP Annual Meeting
Identifying Lupus Patients in Electronic Health Records: Development and Validation of Machine Learning Algorithms and Application of Rule-Based Algorithms
April Jorge¹, Victor M. Castro², April Barnado³, Vivian Gainer², Chuan Hong⁴, Tianxi Cai², Robert Carroll⁵, Leslie Crofford³, Karen Costenbader⁶, Katherine P. Liao⁷, Elizabeth Karlson⁶ and Candace H. Feldman⁶, ¹Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Research Information Systems and Computing, Partners Healthcare, Boston, MA, ³Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN, ⁴Harvard T.H. Chan School of Public Health, Boston, MA, ⁵Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, ⁶Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁷Brigham and Women's Hospital, Boston, MA
Background/Purpose: To utilize electronic health records (EHR) to study SLE, phenotypic algorithms are needed to accurately identify these patients. We aimed to generate an EHR…
Abstract Number: 794 • 2018 ACR/ARHP Annual Meeting
Identification of an Immunodominant Epitope on Rnpc-3 As a Target of Autoantibodies in Patients with Systemic Sclerosis
Michael Mahler¹, Chelsea Bentow¹, Jay Milo¹, Marie Hudson^2,3, Murray Baron³, May Choi⁴ and Marvin J. Fritzler⁴, ¹Research and Development, Inova Diagnostics, San Diego, CA, ²Division of Rheumatology, Jewish General Hospital, Lady Davis Institute for Medical Research, Montreal, QC, Canada, ³Department of Medicine, McGill University, Montreal, QC, Canada, ⁴Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
Background/Purpose: Anti-nuclear antibodies (ANA) are present in approximately 90% of sera from systemic sclerosis (SSc) patients and play an important role in the diagnosis and…
Abstract Number: 2828 • 2018 ACR/ARHP Annual Meeting
Utility of Fecal Calprotectin Levels for the Diagnosis of Inflammatory Bowel Disease in Patients with Spondylorarthritis
Maria Espinosa¹, Consuelo Ramos Giraldez¹, Carolina Merino¹, Belen Ruiz Antoran², Jose Campos¹, Carmen Barbadillo³, Hilda Godoy³, Belen Agudo⁴, Yago Gonzalez⁴, Jose Luis Andreu⁵ and Jesus Sanz¹, ¹Rheumatology, H.U. Puerta de Hierro, Madrid, Spain, ²Pharmacology, H.U. Puerta de Hierro, Madrid, Spain, ³H.U. Puerta de Hierro, Madrid, Spain, ⁴Gastroenterology, H.U. Puerta de Hierro, Madrid, Spain, ⁵Hospital Universitario Puerta de Hierro, Madrid, Spain
Background/Purpose: It is estimated that between 5 and 10% of patients with spondyloarthritis (SpA) are associated with inflammatory bowel disease (IBD).The purpose of our study…
Abstract Number: 817 • 2018 ACR/ARHP Annual Meeting
Current Diagnostic Delays in Vasculitis and Factors Associated with Time to Diagnosis
Antoine G. Sreih¹, Dianne Shaw², Kalen Young³, Cristina Burroughs⁴, Joyce Kullman⁵, Kirthi Machireddy⁶, Carol A. McAlear¹, George Casey³ and Peter A. Merkel⁷, ¹Division of Rheumatology, University of Pennsylvania; Perelman School of Medicine, Philadelphia, PA, ²University of North Carolina, Chapel Hill, NC, ³Vasculitis Foundation, Kansas city, MO, ⁴University of South Florida, Tampa, FL, ⁵Vasculitis, Vasculitis Foundation, Kansas City, MO, ⁶University of Pennsylvania; Perelman School of Medicine, Philadelphia, PA, ⁷Division of Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Despite recent advancements in the evaluation and management of vasculitis, patients with vasculitis continue to encounter diagnostic delays. These delays are often associated…
Abstract Number: 966 • 2018 ACR/ARHP Annual Meeting
Central Triage Clinic for Psoriatic Arthritis – Performance of Triage Methods
Lihi Eder¹, Keith Colaco², Jensen Yeung³, Chandra Farrer⁴ and Dana Jerome³, ¹Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada, ²Institute of Medical Science, University of Toronto, Toronto, ON, Canada, ³University of Toronto, Women's College Hospital, Toronto, ON, Canada, ⁴Rheumatology, Women's College Hospital, Toronto, ON, Canada
Background/Purpose: Accurate triage methods for patients with psoriasis who have musculoskeletal symptoms could lead to earlier access to rheumatology care for patients with psoriatic arthritis…
Abstract Number: 1049 • 2018 ACR/ARHP Annual Meeting
Optical Biomarkers for the Early Diagnosis of Osteoarthritis
Paula Casal Beiroa^1,2, Elena F. Burguera^2,3,4, Tamara Hermida-Gómez^2,3,4, Noa Goyanes⁵, Natividad Oreiro^4,6, Pío González⁷, Francisco J Blanco⁸ and Joana Magalhaes^2,4,9, ¹Unidad de Medicina Regenerativa. Grupo de Investigación en Reumatología (GIR), Instituto de Investigación Biomédica de A Coruña (INIBIC). CHUAC. SERGAS., A Coruña, Spain, ²Centro de Investigaciones Científicas Avanzadas (CICA), Universidad de A Coruña (UDC)., a coruña, Spain, ³Unidad de Medicina Regenerativa, Grupo de Investigación en Reumatología, Agrupación Estratégica CICA-INIBIC, Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade de A Coruña (UDC), A Coruña, Spain, ⁴Centro de Investigación Biomédica en Red (CIBER), madrid, Spain, ⁵Centro de Investigaciones Científicas Avanzadas (CICA), Universidad de A Coruña (UDC)., A Coruña, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruna, Spain, ⁷Grupo de Nuevos Materiales. Departamento de Física Aplicada. Universidad de Vigo., Vigo, Spain, ⁸Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC). Sergas. Universidade de A Coruña (UDC), A Coruña, Spain, ⁹Unidad de Medicina Regenerativa. Grupo de Investigación en Reumatología (GIR), Instituto de Investigación Biomédica de A Coruña (INIBIC). CHUAC. SERGAS., a coruña, Spain
Background/Purpose: Osteoarthritis (OA) is a rheumatic disease characterized by articular cartilage degradation. On its early stages, OA is asymptomatic and its current gold-standard diagnosis (X-Rays),…
Abstract Number: 1236 • 2018 ACR/ARHP Annual Meeting
Peripheral-Blood B-Cell Subset Disturbances in Whipple’s Disease
Maelle Le Goff¹, Divi Cornec², Dewi Guellec¹, Thierry Marhadour¹, Valérie Devauchelle-Pensec¹, Sandrine Jousse-Joulin¹, Marion Herbette¹, Jean-Michel Cauvin³, Clara Le Guillou³, Yves Renaudineau⁴, Jacques-Olivier Pers⁵ and Alain Saraux¹, ¹Rheumatology, CHU Brest, Brest, France, ²Rheumatology and UMR1227, Lymphocytes B et Autoimmunité, CHU Brest, Brest, France, ³CDC, CHU Brest, Brest, France, ⁴U1227, Université de Brest, inserm, Labex IGO, CHU de brest, Brest, France, ⁵U1227, Université de Brest, Inserm, Labex IGO, CHU de Brest, Brest, France
Background/Purpose: Whipple’s disease (WD) is a rare, systemic, disease caused by the intracellular Gram-positive bacterium Tropheryma whipplei (TW). This ubiquitous commensal organism is transmitted among…
Abstract Number: 1442 • 2018 ACR/ARHP Annual Meeting
Differential Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry and a Universal Metabolome Standard Reveals a Metabolome Profile with Consistent Accuracy for Rheumatoid Arthritis
Walter P. Maksymowych¹, Xiaohang Wang², Joel Paschke¹, Rana Dadashova¹, Edna Hutchings¹ and Liang Li², ¹CaRE Arthritis, Edmonton, AB, Canada, ²Chemistry, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Early diagnosis of rheumatoid arthritis (RA) is hampered by suboptimal accuracy of currently available serological biomarkers. Recent advancements in metabolomic profiling include dansylation liquid…

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