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Abstracts tagged "death"

  • Abstract Number: 2827 • 2016 ACR/ARHP Annual Meeting

    Prognostic Significance of Repeat Biopsy in Lupus Nephritis: Histopathologic Worsening Is an Independent Risk Factor for End Stage Renal Disease and Death

    Cristina Arriens1, Sixia Chen2, David Karp3, Ramesh Saxena4, Kamalanathan Sambandam4, Eliza Chakravarty1, Judith A. James5 and Joan T. Merrill6, 1Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Internal Medicine/Division of Rheumatic Diseases, University of Texas Southwestern Medical Center, Dallas, TX, 4Internal Medicine/Division of Nephrology, University of Texas Southwestern Medical Center, Dallas, TX, 5Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 6Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose:  Approximately half of SLE patients develop lupus nephritis (LN), a major cause of morbidity and early mortality. It is known that prolonged renal inflammation…
  • Abstract Number: 2899 • 2015 ACR/ARHP Annual Meeting

    Mortality Related to Pediatric Systemic Lupus Erythematosus: A Multiple Cause-of-Death Analysis in France

    laurent chiche1, sarah malaekah2, alexandre belot3, Brigitte Bader-Meunier4, gregoire rey5, Noémie Jourde-Chiche Sr.6 and mireille eb5, 1internal medicine, Hopital Europeen, Marseille, France, 2pediatry, CHU Lyon, Lyon, France, 3Pediatric Rheumatology, CHU lyon, Hospices Civils de Lyon, HFME, lyon, France, 4Hopital Necker-Enfants Malades, Paris, France, 5cepidc, paris, France, 6Nephrology, Aix-Marseille Université - APHM, Marseille, France

    Background/Purpose: Although regarded as a disease of adulthood, SLE is also seen in children, and is associated with an increased risk for aggressive clinical course…
  • Abstract Number: 60 • 2015 ACR/ARHP Annual Meeting

    Mortality of Systemic Lupus Erythematosus in Puerto Rico Assessed By Multiple-Cause-of-Death Analysis

    Mariangelí Arroyo-Ávila1, José G. Conde2 and Luis M. Vilá1, 1Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, PR, 2School of Medicine and Research Centers in Minority Institutions Program, University of Puerto Rico Medical Sciences Campus, San Juan, PR

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that is associated with a high morbidity and mortality. The specific causes of death vary…
  • Abstract Number: 39 • 2015 ACR/ARHP Annual Meeting

    Baseline Obesity and Subsequent Weight Loss Are Independently Associated with Cardiovascular Mortality in Established Rheumatoid Arthritis

    Bryant R. England1, Joshua F. Baker2, Harlan Sayles3, Kaleb Michaud4,5, Liron Caplan6, Lisa A. Davis6, Grant W. Cannon7, Brian Sauer8, E. Blair Solow9, Andreas Reimold10, Gail S. Kerr11, Pascale Schwab12 and Ted R. Mikuls13, 1Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 2Rheumatology, University of Pennsylvania, Philadelphia, PA, 3University of Nebraska Medical Center, Omaha, NE, 4Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 5National Data Bank for Rheumatic Diseases, Wichita, KS, 6Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, 7Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 8Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 9Rheumatology, UT Southwestern Medical Center, Dallas, TX, 10Rheumatology, VAMC, University of Texas Southwestern Medical Center, Dallas, TX, 11VAMC, Georgetown University, Washington, DC, 12Div Arth & Rheum Dis, Oregon Health & Sci Univ OP09, Portland, OR, 13Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: In the general population, higher body mass index (BMI) is associated with cardiovascular (CV) disease. However, an obesity paradox has been observed in rheumatoid…
  • Abstract Number: 818 • 2014 ACR/ARHP Annual Meeting

    Incident Rheumatoid Arthritis and Risk of Mortality Among Women Followed Prospectively from 1976 to 2010 in the Nurses’ Health Study

    Jeffrey A. Sparks1, Shun-Chiao Chang1,2, Katherine P. Liao1, Bing Lu1, Daniel H. Solomon1, Karen H. Costenbader1 and Elizabeth W. Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose RA has been associated with increased mortality compared to general population estimates. Previous studies were limited due to the inability to directly compare RA…
  • Abstract Number: 817 • 2014 ACR/ARHP Annual Meeting

    Mortality in a Large Cohort of Patients with Early Rheumatoid Arthritis That Were Treated-to-Target for 10 Years

    I.M. Markusse1, L. Dirven2, J.H. van Groenendael3, K.H. Han4, H.K Ronday5, P.J.S.M. Kerstens6, W.F. Lems7,8, T.W.J. Huizinga2 and C.F. Allaart2, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Fransiscus Hospital, Roosendaal, Netherlands, 4Rheumatology, MCRZ hospital, Rotterdam, Netherlands, 5Rheumatology, Haga Hospital, The Hague, Netherlands, 6Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 7Rheumatology, VU Medical Center, Amsterdam, Netherlands, 8Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands

    Background/Purpose: Recent studies showed diverging results about mortality trends in patients with rheumatoid arthritis (RA). Our aim was to determine survival after 10 years of…
  • Abstract Number: 732 • 2014 ACR/ARHP Annual Meeting

    Predictors of Inpatient Mortality in Patients with Systemic Sclerosis: A Case Control Study

    Shiv Tej Sehra1, Chris T. Derk1, Andrew Kelly2 and Joshua Baker3, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Medicine, Pennsylvania Hospital, Philadelphia, PA, 3Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA

    Background/Purpose There are few published studies on predictors of inpatient mortality in patients with systemic sclerosis (SSc). Knowledge of these predictors is important for early…
  • Abstract Number: 476 • 2014 ACR/ARHP Annual Meeting

    Medium-Term Safety  of TNF-Alpha Inhibitors in Rheumatoid Arthritis: A Meta-Analysis of Randomized Controlled Trials

    Lucile Poiroux1, Yannick Allanore2, Andre Kahan3 and Jerome Avouac4, 1Rhumatologie A, Cochin Hospital, Paris, France, 2Rheumatology, Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France, Paris, France, 3Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, 4Cochin Hospital, Paris, France

    Background/Purpose: TNF-a inhibitors have changed the prognosis of rheumatoid arthritis (RA). The number of molecules and the time of exposure have increased. However, few studies…
  • Abstract Number: 2728 • 2014 ACR/ARHP Annual Meeting

    Reduction of MAIT Cell Frequency Associated with Reduced Cell Proliferation and Enhanced Cell Death in Systemic Lupus Erythematosus

    Asako Chiba1, Naoto Tamura2, Eri Hayashi2, Ran Matsudaira3, Yoshinari Takasaki4 and Sachiko Miyake1, 1Immunology, Juntendo University School of Medicine, Tokyo, Japan, 2Rheumatology, Juntendo University School of Medicine, Tokyo, Japan, 3Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo, Japan, 4Department of Rheumatology, Juntendo University School of Medicine, Tokyo, Japan

    Background/Purpose: Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes which are restricted by the MHC-related molecule-1 (MR1) and express a semi-invariant TCRα chain: Vα7.2-Jα33 in…
  • Abstract Number: 2620 • 2014 ACR/ARHP Annual Meeting

    Mortality and Survival in Systemic Lupus Erythematosus Patients: Trends in a Spanish Cohort from 1985 to 2013

    Sergi Heredia1, Javier Narváez2, Andrea Zacarias1, Milagros Ricse1, Gloria Albert1, Eulalia Armengol1, Helena Borrell1, Olga Capdevila3, Francesca Mitjavila3, Toni Rozadilla1, Xavier Juanola4 and Joan Miquel Nolla1, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, 3Internal Medicine, Hospital Universitario de Bellvitge, Barcelona, Spain, 4Rheumatology, University Hospital Bellvitge, Barcelona, Spain

    Background/Purpose: To study the mortality, survival and causes of death in a Spanish cohort of patients with systemic lupus erythematosus (SLE) over a 28-year period…
  • Abstract Number: 2053 • 2014 ACR/ARHP Annual Meeting

    Mortality Decreases in Patients with Rheumatoid Arthritis: a 15-Year Prospective Cohort Study

    Joëlle van den Hoek1,2, Hendriek C. Boshuizen3, Leo D. Roorda4, Gerard J. Tijhuis5, Mike T. Nurmohamed5, Trudi van den Bos2 and Joost Dekker6,7, 1Rehabilitation Research Center, Reade, Rehabilitation | Rheumatology, Amsterdam, Netherlands, 2Social Medicine, Academic Medical Center, Amsterdam, Netherlands, 3National Institute of Public Health and the Environment, Bilthoven, Netherlands, 4Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, 5Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 6Rehabilitation Medicine, Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 7Reade, centre for Rehabilitation and Rheumatology, Amsterdam, Netherlands

    Background/Purpose Patients with rheumatoid arthritis (RA) have a higher mortality risk than the general population, with similar patterns over the last decades. However, more recent…
  • Abstract Number: 1781 • 2014 ACR/ARHP Annual Meeting

    Long-Term Outcomes Among Patients with Renal Disease Secondary to ANCA-Associated Vasculitis: Temporal Trends over 25 Years

    Rennie L. Rhee1, Susan L Hogan2, Caroline J. Poulton2, Julie Anne G. McGregor2, J. Richard Landis3, Ronald Falk4 and Peter A. Merkel5, 1Rheumatology, University of Pennsylvania, Philadelphia, PA, 2UNC Kidney Center, Chapel Hill, NC, 3Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, 4Dept of Nephrology and Hypertension, UNC Kidney Center, Chapel Hill, NC, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose Significant advances have been made in the diagnosis and treatment of patients with ANCA-associated vasculitis (AAV).  However, little is known about how these advances…
  • Abstract Number: 1071 • 2014 ACR/ARHP Annual Meeting

    What Is the Impact of Chronic Systemic Inflammation Such As Rheumatoid Arthritis on Mortality Following Cancer?

    Julia Simard1,2, Sara Ekberg3, Anna Johansson4 and Johan Askling2,5, 1Division of Epidemiology, Health Research and Policy Department, and Division of Immunology & Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, 2Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, 3Dept of Medical Epidemiology of Biostatistic, Karolinska Institutet, Stockholm, Sweden, 4Dept of Medical Epidemiology and Biostatistics, Karolinska Institutet, stockholm, Sweden, 5Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose:   Emerging evidence links inflammation and immune-competence to cancer progression and outcome. The few studies addressing cancer survival in the context of systemic inflammation,…
  • Abstract Number: 1066 • 2014 ACR/ARHP Annual Meeting

    Factors Associated with Recording of Rheumatoid Arthritis on Death Certificate

    Emily Molina1, Jose Felix Restrepo2, Inmaculada del Rincon1, Daniel Battafarano3 and Agustin Escalante4, 1Rheumatology, University of Texas Health Science Center, San Antonio, TX, 2Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 3Rheumatology, San Antonio Military Medical Center, JBSA - Ft Sam Houston, TX, 4Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX

    Factors Associated with Recording of Rheumatoid Arthritis on Death Certificates Background/Purpose: Death certificates can be used to study mortality due to a particular disease. However, rheumatoid…
  • Abstract Number: 2059 • 2013 ACR/ARHP Annual Meeting

    Mortality In Polymyositis and Dermatomyositis: A Single Centre Study

    Erin Vermaak1, Gavin Shaddick2 and Neil J McHugh1,3, 1Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2Department of Mathematics, University of Bath, Bath, United Kingdom, 3Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

    Background/Purpose:  PM and DM are rare chronic inflammatory disorders of muscle, and data on long-term prognosis and outcomes are lacking.  Previous studies have reported 5-year…
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