ACR Meeting Abstracts

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Abstracts tagged "death"

  • Abstract Number: 1089 • 2019 ACR/ARP Annual Meeting

    Causes of Death in ANCA-Associated Vasculitis According to ANCA Type

    Zachary Wallace1, Xiaoqing Fu 1, Tyler Harkness 1, John Stone 2, Yuqing Zhang 3 and Hyon K. Choi 3, 1Massachusetts General Hospital, Boston, 2Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, 3Massachusetts General Hospital, Boston, MA

    Background/Purpose: Survival has improved in ANCA-associated vasculitis (AAV) with evolving management strategies, but patients remain at an increased risk of death compared to the general…
  • Abstract Number: 941 • 2018 ACR/ARHP Annual Meeting

    Causal Inference Methods for the Effect of Rheumatoid Arthritis on Mortality Independent of Lifestyle and Clinical Factors before and after RA Diagnosis

    Jeffrey A. Sparks1, Kazuki Yoshida1,2, Tzu-Chieh Lin3, Carlos Camargo4, Benjamin Raby5, Hyon K. Choi6, Medha Barbhaiya7, Sara K. Tedeschi1, Bing Lu8, Karen Costenbader1 and Elizabeth Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Harvard T.H. Chan School of Public Health, Boston, MA, 3Amgen, Thousand Oaks, CA, 4Emergency Medicine, Massachusetts General Hospital, Boston, MA, 5Pulmonary, Brigham and Women's Hospital, Boston, MA, 6Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 7Rheumatology, Hospital for Special Surgery, New York, NY, 8Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: RA is associated with increased total, cardiovascular, and respiratory mortality compared to the general population. This excess RA mortality may be mediated through lifestyle,…
  • Abstract Number: 1515 • 2018 ACR/ARHP Annual Meeting

    Malignancy in Japanese Patients with Rheumatoid Arthritis Treated with Tofacitinib: Interim Analysis of All-Case Post-Marketing Surveillance

    Naoto Tamura1, Masataka Kuwana2, Tatsuya Atsumi3, Syuji Takei4, Masayoshi Harigai5, Takao Fujii6, Hiroaki Matsuno7, Tsuneyo Mimori8, Shigeki Momohara9, Kazuhiko Yamamoto10, Yoshinari Takasaki11, Kazuto Nomura12, Yutaka Endo12, Tomohiro Hirose12, Yosuke Morishima12, Naonobu Sugiyama12, Noritoshi Yoshii12 and Michiaki Takagi13, 1Juntendo University, Tokyo, Japan, 2Nippon Medical School, Tokyo, Japan, 3Hokkaido University, Sapporo, Japan, 4Medical Center for Children, Kagoshima, Japan, 5Tokyo Women’s Medical University, Tokyo, Japan, 6Wakayama Medical University, Wakayama, Japan, 7Matsuno Clinic for Rheumatic Diseases, Toyama, Japan, 8Kyoto University, Kyoto, Japan, 9Hakkeikai Inc Medical Institution, Shizuoka, Japan, 10The University of Tokyo, Tokyo, Japan, 11Juntendo Koshigaya Hospital, Juntendo University Faculty of Medicine, Saitama, Japan, 12Pfizer Japan Inc, Tokyo, Japan, 13Yamagata University Faculty of Medicine, Yamagata, Japan

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. The efficacy and safety of tofacitinib have been demonstrated in patients (pts)…
  • Abstract Number: 1844 • 2018 ACR/ARHP Annual Meeting

    Racial Disparities and Accelerated SLE Mortality from a Population-Based Registry: The Georgia Lupus Registry

    S. Sam Lim1, Charles G. Helmick2, Gaobin Bao3, Caroline Gordon4, Jennifer M. Hootman2 and Cristina Drenkard5, 1Emory University School of Medicine, Atlanta, GA, 2Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, 3Department of Medicine, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA, 4Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 5Medicine/Rheumatology, Emory University, Atlanta, GA

    Background/Purpose: Population-based SLE mortality studies have depended on administrative data from vital statistics records to identify cases. However, a high proportion of SLE deaths have…
  • Abstract Number: 1888 • 2018 ACR/ARHP Annual Meeting

    SLE Among the Leading Causes of Years of Potential Life Lost in Young Women: Population-Based Study, 2000-2015

    Eric Yen and Ram R. Singh, UCLA, Los Angeles, CA

    Background/Purpose: Ten-year survival of SLE has improved from <50% in the 1950s to ~95% in the 2000s. However, the relative and true disease burden for…
  • Abstract Number: 2803 • 2018 ACR/ARHP Annual Meeting

    48-Year Trends in Systemic Sclerosis Mortality in the United States, 1968-2015: Steady Decrease for 15 Years after 33 Years of Continuous Increase

    Eric Yen, Devanshu Singh and Ram R. Singh, UCLA, Los Angeles, CA

    Background/Purpose: A comprehensive evaluation of long-term trends in systemic sclerosis (SSc) mortality is important to understand the influence of recent advances in SSc management and…
  • Abstract Number: 2982 • 2018 ACR/ARHP Annual Meeting

    Normal Mortality of the Cobra Early Rheumatoid Arthritis Trial Cohort after 23 Years Follow up

    Pomme Poppelaars1, Lilian van Tuyl2 and Maarten Boers1,3, 1Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, 3Epidemiology & Biostatistics, Epidemiology & Biostatistics | VU University Medical Center, Netherlands, Amsterdam, Netherlands

    ACR abstractBackground/Purpose: Mortality in patients with rheumatoid arthritis (RA) is higher than in the general population. In most studies this becomes apparent only after more…
  • Abstract Number: 840 • 2017 ACR/ARHP Annual Meeting

    Mortality Post Hip Fracture in Rheumatoid Arthritis Compared to General Population Controls, a Population-Based Study

    C. Allyson Jones1, Pierre Guy2, Hui Xie3, Eric C. Sayre4 and Diane Lacaille5,6, 1Physical Therapy, University of Alberta, Edmonton, AB, Canada, 2Department of Orthopaedics, University of British Columbia / Centre for Hip Health and Mobility, Vancouver, BC, Canada, 3Biostatistics, Faculty of Health Sciences, Simon Fraser University / Arthritis Research Canada, Burnaby, BC, Canada, 4Arthritis Research Canada, Richmond, BC, Canada, 5University of British Columbia, Arthritis Research Canada, Richmond, BC, Canada, 6Arthritis Research Canada/ University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: In prior work, we found a higher incidence of hip fractures in RA than age and sex matched general population controls (4.1 vs. 2.9…
  • Abstract Number: 987 • 2017 ACR/ARHP Annual Meeting

    Death Certificates Do Not Accurately Identify SLE Patients

    Kelly Kaysen, Cristina Drenkard, Gaobin Bao and S. Sam Lim, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA

    Background/Purpose:  Mortality rates are higher in SLE patients compared to the general population, and research on SLE mortality is ongoing. The majority of mortality studies…
  • Abstract Number: 1429 • 2017 ACR/ARHP Annual Meeting

    Incidence Rates of Adverse Events with Death As an Outcome during Abatacept Treatment in RA: Results from an Integrated Data Analysis from 16 Clinical Trials

    D Fleming1, TA Simon1, A Torbeyns2, U Meier-Kriesche1 and A Johnsen1, 1Bristol-Myers Squibb, Princeton, NJ, 2Bristol-Myers Squibb, Braine l’Alleud, Belgium

    Background/Purpose: Patients with RA have a 1.5–2-fold increased risk of mortality compared with the general population. The association between mortality rates and different RA treatments…
  • Abstract Number: 1804 • 2017 ACR/ARHP Annual Meeting

    Patient-Reported Outcomes and Damage Predict Mortality in Lupus

    Desiree R Azizoddin1, Meenakshi Jolly2, Patricia P. Katz3 and Edward H. Yelin4, 1Department of Psychology, Loma Linda University, Loma Linda, CA, 2Rush, Chicago, IL, 3Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 4Medicine/Rheumatology, University of California San Francisco, San Francisco, CA

    Background/Purpose: Physician-assessed disease activity and damage predict mortality in systemic lupus erythematosus (SLE). Patient-reported outcomes (PROs) are known predictors of mortality in other chronic diseases,…
  • Abstract Number: 2846 • 2017 ACR/ARHP Annual Meeting

    Cause-Specific Mortality in Gout: Novel Findings of Elevated Risk of Renal-Related and Decreased Risk of Dementia-Related Death

    Ana Beatriz Vargas-Santos1, Tuhina Neogi2, Geraldo Castelar-Pinheiro1 and Aleksandra Turkiewicz3, 1Internal Medicine - Rheumatology, State University of Rio de Janeiro, Rio de Janeiro, Brazil, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden

    Background/Purpose: There is recognized higher mortality among gout patients, with cardiovascular (CV) mortality having been previously reported. The present study aimed to examine cause-specific mortality…
  • Abstract Number: 203 • 2016 ACR/ARHP Annual Meeting

    Allopurinol Dose Escalation and Mortality Among Patients with Gout: A National Propensity-Matched Cohort Study

    Brian W Coburn1,2, Kaleb Michaud3, Debra A Bergman2 and Ted R Mikuls4,5, 1Research Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, 2Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 3Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 4Veteran Affairs Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 5Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Allopurinol Dose Escalation and Mortality among Patients with Gout: A National Propensity-Matched Cohort Study  Background/Purpose: Numerous epidemiologic studies show that hyperuricemia and gout are associated…
  • Abstract Number: 993 • 2016 ACR/ARHP Annual Meeting

    Chronic Widespread Pain Associated with Premature Mortality in a UK National Prospective Study

    Gary J. Macfarlane1,2 and Gareth T. Jones3,4, 1Epidemiology Group, University of Aberdeen, Aberdeen, United Kingdom, 2Aberdeen Centre for Arthritris and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, 3Aberdeen Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, 4Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom

    Background/Purpose: A small number of studies have examined the long-term consequences of having chronic widespread pain (CWP). Most report premature mortality, but the magnitude and…
  • Abstract Number: 2794 • 2016 ACR/ARHP Annual Meeting

    Sustained Complete Remission in Lupus Nephritis

    Rattapol Pakchotanon1, Dafna D. Gladman2, Jiandong Su2 and Murray Urowitz3, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 3Medicine, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada

    Background/Purpose: The durability of renal remission might be a predictor of good long-term renal outcome and survival in patients with lupus nephritis (LN). We aimed…
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