Abstracts tagged "Damage Index"

Abstract Number: 0271 • ACR Convergence 2020
External Validation of the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) as a Predictor of Mortality and Organ Damage Accrual in Systemic Lupus Erythematosus
Alicia Malone¹, Alexandra Legge¹ and John Hanly¹, ¹Dalhousie University, Halifax, NS, Canada
Background/Purpose: Using data from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort, a frailty index (FI) was recently developed as a measure of susceptibility…
Abstract Number: 0853 • ACR Convergence 2020
Gradual Glucocorticoid Withdrawal Is Safe in Clinically Quiescent Systemic Lupus Erythematosus
Konstantinos Tselios¹, Dafna Gladman², Jiandong Su³ and Murray Urowitz¹, ¹University Health Network, University of Toronto, Toronto, ON, Canada, ²Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ³University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, ON, Canada
Background/Purpose: Systemic lupus erythematosus (SLE) patients are usually treated with glucocorticoids even during periods of clinically quiescent disease. A recent study showed that abrupt glucocorticoid…
Abstract Number: 0864 • ACR Convergence 2020
Effect of Cumulative Hydroxychloroquine Dose on Prevention of Damage Progression in Patients with Systemic Lupus Erythematosus
Lisa Zhu¹, Manpreet Singh², Caroline Siegel³, Lori Sahakian², Jennifer Grossman⁴ and Maureen McMahon⁵, ¹University of California, Los Angeles, Van Nuys, CA, ²University of California, Los Angeles, Los Angeles, CA, ³Hospital for Special Surgery, New York, NY, ⁴University of California, Los Angeles, Sherman Oaks, CA, ⁵University of California Los Angeles, Los Angeles, CA
Background/Purpose: Hydroxychloroquine (HCQ) has demonstrated a wide array of beneficial effects in patients with systemic lupus erythematosus (SLE), with regard to disease activity, flare rates,…
Abstract Number: 1021 • ACR Convergence 2020
Organ Damage in Systemic Lupus Erythematosus Is Attributable More to Comorbidity (Hypertension) and Less to Socioeconomic Status
Romy Kallas¹, Jessica Li², Daniel Goldman³ and Michelle Petri³, ¹Johns Hopkins Medical Institution, Baltimore, MD, ²Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University School of Medicine, Timonium, MD
Background/Purpose: Multiple variables are known to contribute to development of organ damage in SLE patients, including prednisone use and ethnicity. The aim of this study…
Abstract Number: 1167 • ACR Convergence 2020
Capturing the Range of Disease Involvement in Localized Scleroderma: The Total Morbidity Score
Suzanne Li¹, Aashka Patel¹, Elena Pope², Thomas Mason³, Vidya Sivaraman⁴, Fatma Dedeoglu⁵, Kathryn Torok⁶, Katie Stewart⁷, Gloria Higgins⁸, C. Egla Rabinovich⁹, Robert Fuhlbrigge¹⁰, Maria Ibarra¹¹, Sandy Hong¹², Polly Ferguson¹³, Mara Becker¹⁴, Brian Feldman¹⁵, Ronald Laxer¹⁵ and CARRA Investigators¹⁶, ¹Hackensack University Medical Center, Hackensack, ²Hospital For Sick Kids, Toronto, ON, Canada, ³Mayo Clinic, Rochester, MN, ⁴Nationwide Children's Hospital, Bexley, OH, ⁵Boston Children's Hospital, Boston, MA, ⁶University of Pittsburgh, Pittsburgh, PA, ⁷UT Southwestern, Dallas, TX, ⁸Nationwide Childrens Hospital/ The Ohio State University, Columbus, OH, ⁹Duke University Hospital, Durham, NC, ¹⁰University of Colorado, Denver, CO, ¹¹Children's Mercy Kansas City, Kansas City, MO, ¹²University of Iowa Stead Family Children's Hospital, Iowa City, IA, ¹³University of Iowa Carver College of Medicine, Iowa City, IA, ¹⁴Duke University School of Medicine, Durham, NC, ¹⁵The Hospital for Sick Children, Toronto, ON, Canada, ¹⁶CARRA, Durham
Background/Purpose: Localized scleroderma (LS) is a chronic inflammatory and fibrosing disease that causes both cutaneous and extracutaneous (EC) damage. EC involvement (ECI) is common in juvenile…
Abstract Number: 1258 • ACR Convergence 2020
Trajectory of Damage Accrual in African-American vs. Caucasian Systemic Lupus Erythematosus
Romy Kallas¹, Jessica Li², Daniel Goldman³ and Michelle Petri³, ¹Johns Hopkins Medical Institution, Baltimore, MD, ²Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University School of Medicine, Timonium, MD
Background/Purpose: African-Americans have a higher incidence/prevalence of SLE, more lupus nephritis, higher rates of end stage renal disease and higher mortality than Caucasians. The aim…
Abstract Number: 1263 • ACR Convergence 2020
Association of the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) and Damage Accrual in Long Standing Systemic Lupus Erythematosus
Kaitlin Lima¹, Alexandra Legge², John Hanly², Jungwha Lee³, Jing Song³, Anh Chung³ and Rosalind Ramsey-Goldman⁴, ¹Northwestern University, Chicago, IL, ²Dalhousie University, Halifax, NS, Canada, ³Northwestern University, Chicago, ⁴Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: The Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) was recently shown to predict mortality and damage accrual in the SLICC inception cohort. The…

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