Abstracts tagged "cross-sectional studies"

Abstract Number: 1530 • 2019 ACR/ARP Annual Meeting
Real World Effectiveness of Secukinumab in Patients with Ankylosing Spondylitis: Findings from a Recent Cross Sectional Survey of Rheumatologists and Patients in Europe
Uta Kiltz ¹, Elizabeth Holdsworth², Haijun Tian ³, Nicola Booth ⁴, Papa Anthony ⁵, Lina Helsche ⁶, Dorothy Keininger ⁶ and Philip G Conaghan ⁷, ¹Rheumazentrum Ruhrgebiet/Ruhr University Bochum, Herne, Germany, Herne, Germany, ²Adelphi Real World, Manchester, England, United Kingdom, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁴Adelphi Real World, Bollington, United Kingdom, ⁵Adelphi Real World, Macclesfield, England, United Kingdom, ⁶Novartis Pharma AG, Basel, Basel-Landschaft, Switzerland, ⁷Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom
Background/Purpose: Ankylosing spondylitis (AS) can lead to reduced physical functioning and quality of life. Secukinumab has demonstrated clinical benefits in AS patients in clinical trials1-2.…
Abstract Number: 565 • 2018 ACR/ARHP Annual Meeting
Genetic Polymorphism in Dihydrofolate Reductase Impacts Methotrexate Polyglutamation in Adult Rheumatoid Arthritis
Thierry Dervieux¹, Marie Grosjean², Chuang Jiang^3,4, Kelley Brady¹, Kjeld Schmiegelow², Joel Kremer⁵ and Jun Yang⁴, ¹Exagen Diagnostics, Inc., Vista, CA, ²University Hospital Rigshospitalet, Copenhagen, Denmark, ³Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China, ⁴Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN, ⁵Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: Methotrexate (MTX) is anti-folate activated to MTX polyglutamates (MTXPGs). MTX metabolism includes multiple enzyme-mediated reactions and genetic polymorphisms in these genes are linked to…
Abstract Number: 638 • 2018 ACR/ARHP Annual Meeting
Diagnostic Delay and Associated Factors in Axial Spondyloarthritis across Europe. Results from the European Map of Axial Spondyloarthritis Survey
Laure Gossec¹, Marco Garrido-Cumbrera^2,3,4, Denis Poddubnyy^5,6, David Galvez-Ruiz^2,4, Christine Bundy⁷, Carlos Jesus Delgado Dominguez^2,4, Raj Mahapatra⁸, Pedro Plazuelo-Ramos³, Souzi Makri⁹ and Victoria Navarro-Compán¹⁰, ¹Sorbonne Universités, Paris, France, ²Health & Territory Research (HTR), Seville, Spain, ³Spanish Coordinator of Spondyloarthritis Associations (CEADE), Madrid, Spain, ⁴Universidad de Sevilla, Seville, Spain, ⁵German Rheumatism Research Centre, Berlin, Germany, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷Cardiff University, Cardiff, United Kingdom, ⁸Ankylosing Spondylitis International Federation (ASIF), London, United Kingdom, ⁹Cyprus League Against Rheumatism, Nicosia, Cyprus, ¹⁰Immuno-Rheumatology research group, IdiPaz. La Paz University Hospital, Madrid, Spain
Background/Purpose: Axial Spondyloarthritis (axSpA) is a chronic inflammatory disease associated with a long diagnostic delay (DD); however, recent data suggests improvements1. The purpose was to…
Abstract Number: 2155 • 2018 ACR/ARHP Annual Meeting
Diagnosis of Systemic Sclerosis in the United Kingdom: An Observational Study Using the Clinical Practice Research Datalink
Alicia Gayle¹, Nils Schoof², Margarida Alves², Deborah Clarke³, Chris Poole¹, Christina Raabe², Prithwiraj Das¹ and Toby Maher⁴, ¹Boehringer Ingelheim Ltd., Bracknell, United Kingdom, ²Boehringer Ingelheim International GmbH, Ingelheim, Germany, ³Department of Medical Affairs, Boehringer Ingelheim Ltd., Bracknell, United Kingdom, ⁴University College London and Royal Brompton Hospital, London, United Kingdom
Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune disease that is characterised by fibroblast dysfunction and excess extracellular matrix deposition that leads to skin thickening and…
Abstract Number: 584 • 2017 ACR/ARHP Annual Meeting
Factors Associated with the “Bamboo Spine” Phenotype – Data from the Comospa Study
Koei Oh¹, Anna Molto², Corinne Miceli-Richard³, Soksay Singvongsa⁴, Adrien Etcheto⁴ and Maxime Dougados⁴, ¹Departmen of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France, ²Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ³Department of Rheumatolgy, Paris Descartes University, Hôpital Cochin, Paris, France, ⁴Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France
Background/Purpose: The factors associated with “Bamboo spine” occurrence, i.e. the most severe axial phenotype of SpA patients, have been poorly assessed to date. The aim…
Abstract Number: 2194 • 2017 ACR/ARHP Annual Meeting
The Relationship between the Number of Prescription Medications and Physical Activity Amongst Patients with or at High Risk for Knee Osteoarthritis
Nivaas Thanoo¹, Abigail Gilbert², Jing Song³, Dorothy D. Dunlop⁴ and Rowland W. Chang⁵, ¹Feinberg School of Medicine, Chicago, IL, ²Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Inst Hlthcare Studies, Northwestern Univ/ Feinberg, Chicago, IL, ⁵Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Physical activity amongst individuals with knee osteoarthritis (KOA) has been linked to improved pain, functional status, and less disability. It is important to understand…
Abstract Number: 2297 • 2016 ACR/ARHP Annual Meeting
Serum Urate and Its Association with Race in Young Adults: Baseline Analysis from a Randomized Clinical Trial
Michael B. Saddekni¹, Angelo L. Gaffo¹, Phillip J. Foster¹, Elizabeth J. Rahn¹, Stephanie R. Biggers¹, Peng Li² and Kenneth G. Saag¹, ¹Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Increased levels of serum urate (sUA) have been reported in association with hypertension, chronic kidney disease, and obesity. All these conditions are over-represented in…
Abstract Number: 2729 • 2016 ACR/ARHP Annual Meeting
Treatment Patterns, Unmet Need, and Impact of Psoriatic Arthritis on Patient-Reported Outcomes in the United States
Alice Gottlieb¹, Jorge Gratacos-Masmitja², April Armstrong³, Jo Lambert⁴, Astrid van Tubergen⁵, Ara Dikranian⁶, Birol Emir⁷, Eustratios Bananis⁸, Tim Smith⁷, Laraine Aikman⁹ and Linda Chen⁷, ¹Tufts University School of Medicine, Boston, MA, ²Servicio de Reumatología, Corporació Sanitoria Parc Taulíde Sabadell, Barcelona, Spain, ³Department of Dermatology, University of Southern California, Los Angeles, CA, ⁴Department of Dermatology, Ghent University Hospital, Ghent, Belgium, ⁵Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁶San Diego Arthritis Clinic, San Diego, CA, ⁷Pfizer Inc, New York, NY, ⁸Pfizer Inc, Collegeville, PA, ⁹Pfizer Ltd, Walton Oaks, United Kingdom
Background/Purpose: This non-interventional, cross-sectional descriptive exploratory analysis aimed to characterize patients (pts) with PsA in the 2015 National Health and Wellness Survey (NHWS) and determine…
Abstract Number: 48 • 2016 ACR/ARHP Annual Meeting
Fibromyalgia Impact Is a Potential Mediator for the Associations of Self-Efficacy and Pain Catastrophizing with Physical Functioning in Persons with Fibromyalgia
Sun Yu¹, Lori Lyn Price², Jeffrey B. Driban¹, William F. Harvey¹ and Chenchen Wang¹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA
Background/Purpose: Fibromyalgia (FM) is a chronic multidimensional disorder that causes physical and psychological impairment, incurring significant healthcare costs. Self-efficacy and pain catastrophizing have been shown…
Abstract Number: 119 • 2016 ACR/ARHP Annual Meeting
Impact of Socioeconomic Status on Disease Outcomes in Japanese Patients with Rheumatoid Arthritis Under the Japanese National Insurance System
Akira Onishi¹, Goichi Kageyama², Yo Ueda², Ikuko Naka², Kosaku Tsuda², Takaichi Okano², Soshi Takahashi², Kengo Akashi², Sho Sendo², Yoshinori Kogata², Jun Saegusa² and Akio Morinobu², ¹Department for Rheumatology, Kobe University Hospital, Kobe, Japan, ²Department of Rheumatology, Kobe University Hospital, Kobe, Japan
Background/Purpose: Several studies showed lower socioeconomic status (SES) was associated with higher disease activity and lower quality of life (QOL) in patients with rheumatoid arthritis…
Abstract Number: 453 • 2016 ACR/ARHP Annual Meeting
Adaptation and Validation the Systemic Sclerosis Quality of Life Questionnaire into Spanish Using Rasch Analysis
Mwidimi Ndosi¹, Silvia Garcia-Diaz², Begonya Alcacer-Pitarch³, Francesco Del Galdo⁴, Vicenç Torrente-Segarra² and Anthony C. Redmond⁴, ¹Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ²Rheumatology, Hospital Sant Joan Despí Moisès Broggi-CSI-, Barcelona, Spain, ³Leeds Institute of Rheumatic and Musculoskeletal medicine, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom
Background/Purpose: Systemic Sclerosis (SSc) represents a group of heterogeneous autoimmune disorders of connective tissue characterized by progressive fibrosis of the skin and internal organs [1].…
Abstract Number: 1508 • 2016 ACR/ARHP Annual Meeting
Prevalence and Clinical Characteristics of Rheumatoid Arthritis in Sickle Cell Patients: A Cross-Sectional Analysis
David J. Ozeri¹, Joshy Pathiparampil², Randolph Sanchez² and Isabel M. McFarlane³, ¹Rheumatology, SUNY Downstate Medical Center, brooklyn, NY, ²Internal Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ³Rheumatology, SUNY Downstate Medical Center, Brooklyn, NY
Title: Prevalence and Clinical Characteristics of Rheumatoid Arthritis in Sickle Cell Patients Background/Purpose: Rheumatoid arthritis (RA) has been rarely reported in association with sickle cell…
Abstract Number: 44 • 2015 ACR/ARHP Annual Meeting
The Prevalence of Depression and Anxiety in a Cross-Section of Rheumatological Conditions
Faith Matcham¹, Nicola J. Gullick², Matthew Hotopf³, Sam Norton⁴, Sophia Steer⁵ and James Galloway⁶, ¹Psychological Medicine Clinical Academic Group, King's College London, London, United Kingdom, ²Rheumatology, Department of Rheumatology, King`s College Hospital NHS Foundation Trust, London, United Kingdom, ³Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom, ⁴Institute of Psychiatry, King's College London, London, United Kingdom, ⁵Rheumatology Dept, Kings College Hospital, London, United Kingdom, ⁶Academic Department of Rheumatology, King´s College London, London, United Kingdom
Background/Purpose: Depression and anxiety have detrimental effects on quality-of-life, treatment response and disease outcomes. Whilst psychological morbidity has been described in individual rheumatic diseases, less…
Abstract Number: 2265 • 2015 ACR/ARHP Annual Meeting
Prevalence and Physical and Mental Health Patterns of Rheumatic and Musculoskeletal Diseases in Portugal: Results from a National Health Survey
Jaime C Branco¹, Ana M. Rodrigues², Nelia Gouveia³, Leonor P Costa⁴, Monica Eusebio⁵, Sofia Ramiro^2,4,6, Pedro Machado^4,7,8, Filipa Mourão^4,9,10, Inês Silva^9,11, Pedro Laires⁴, Alexandre Sepriano^4,12, Filipe Araújo^4,13, Sónia Gonçalves⁴, Pedro S Coelho^4,14, Viviana Tavares⁴, Jorge Cerol^4,15, Jorge M Mendes^4,14, Loreto Carmona¹⁶ and Helena Canhao¹⁷, ¹NOVA Medical School/faculdade de ciências médicas, Universidade Nova de Lisboa, Lisboa, Portugal, ²CEDOC - Chronic Diseases FCM NOVA, NOVA Medical School - Faculdade de Ciências Médicas da UNL, Lisbon, Portugal, ³CEDOC - Chronic Diseases FCM NOVA, NOVA Medical School - Faculdade Ciências Médicas da UNL, Lisbon, Portugal, ⁴EpiReumaPt Study Group, Lisbon, Portugal, ⁵Portuguese Society of Rheumatology, Lisbon, Portugal, ⁶Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁷Clínica Universitária de Reumatologia, Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal, ⁸University College London - MRC Centre for Neuromuscular Diseases,, London, United Kingdom, ⁹Centro Hospitalar Lisboa Ocidental (CHLO- E.P.E.), Lisbon, Portugal, ¹⁰NOVA Medical School - Faculdade Ciências Médicas da Universidade Nova de Lisboa, Lisbon, Portugal, ¹¹EpiReumaPt Study Group, lisbon, Portugal, ¹²Rheumatology, Hospital de Egas Moniz - CHLO, Lisbon, Portugal, Lisbon, Portugal, ¹³Rheumatology, Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, ¹⁴NOVA Information Management School, Lisbon, Portugal, ¹⁵Portuguese Catholic University, Lisbon, Portugal, ¹⁶Instituto de Salud Musculoesquelética, Madrid, Spain, ¹⁷Hospital Santa Maria - Serviço de Reumatologia, Lisboa, Portugal
Background/Purpose: Rheumatic and musculoskeletal diseases (MSKD) are a prevalent leading cause of disability and consume a large amount of healthcare and social resources. MSKD have been…
Abstract Number: 2481 • 2015 ACR/ARHP Annual Meeting
Work Disability in a Cohort of Patients with Psoriatic Arthritis
Cecilia Zaffarana¹, Osvaldo Luis Cerda¹, Josefina Gallino Yanzi¹, Margarita Landi¹, Emilce Schneeberger¹, Ignacio Carrillo¹, María del Carmen Gonzalez Guzmán¹, Jose A Maldonado Cocco¹, Susana Gagliardi¹ and Gustavo Citera², ¹Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Rheumatology, Consultorios Reumatológicos Pampa, Buenos Aires, Argentina
Background/Purpose: Several studies showed that unemployment and work disability are high in patients with Psoriatic Arthritis (PsA). Te purpose of this study is to evaluate work…

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