ACR Meeting Abstracts

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Abstracts tagged "Crohn’s Disease"

  • Abstract Number: 1823 • 2019 ACR/ARP Annual Meeting

    Magnetic Resonance Enterography as a Screening Tool to Detect Sacroiliitis in Crohn’s Disease: Association with Clinical and Endoscopic Markers of Crohn’s Disease Activity

    Fardina Malik1, Irvine Levine 2, Gabrielle Castillo 1, Brian Jaros 2, Erin Alaia 1, Justin Ream 2, Jordan E. Axelrad 1, David P. Hudesman 1 and Jose Scher 3, 1New York University School of Medicine, New York, NY, 2New York University School of Medicine, New York, 3Division of Rheumatology, New York University School of Medicine and NYU Langone Orthopedic Hospital, New York, NY

    Background/Purpose: Prevalence of sacroiliitis (SI) in Crohn’s disease (CD) varies widely (range 4% -39%), depending on criteria utilized to define the disease (e.g. inflammatory back…
  • Abstract Number: 2883 • 2018 ACR/ARHP Annual Meeting

    Testing for Anti-Microbial Antibodies with Cross-Reactivity to Human Tissue in Autoimmune Diseases

    Peilin Zhang, Lawrence Minardi, J. Todd Kuenstner and Stephen Zekan, PZM Diagnostics, LLC, Charleston, WV

    Background/Purpose: Autoantibodies are defining features of autoimmune diseases. How and why the autoantibodies are produced and how these autoantibodies relate to pathogenesis is poorly understood.…
  • Abstract Number: 367 • 2018 ACR/ARHP Annual Meeting

    Incidence of Inflammatory Bowel Disease (IBD) Among Patients (Pts) with Other Chronic Inflammatory Diseases (CID) Treated with Interleukin-17a (IL-17a) or Phosphodiesterase 4 (PDE4) Inhibitors

    Bruno Emond1, Lorie A. Ellis2, Soumya D Chakravarty3, Martin Ladouceur1 and Patrick Lefebvre1, 1Analysis Group, Inc., Montréal, QC, Canada, 2Janssen Scientific Affairs, LLC, Horsham, PA, 3Janssen Scientific Affairs, LLC/Drexel University School of Medicine, Horsham/Phila, PA

    Background/Purpose:  IBD is often associated with other CID, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and psoriasis (PsO). Newer biologic agents…
  • Abstract Number: 1866 • 2018 ACR/ARHP Annual Meeting

    Incidence of Inflammatory Bowel Disease Among Patients Treated with Ixekizumab: An Update on Adjudicated Data from an Integrated Database of Patients with Psoriasis and Psoriatic Arthritis

    Mark C. Genovese1, Jean-Frederic Colombel2, Amanda M. Gellett3, Wen Xu3 and Dana Hardin3, 1Department of Medicine, Stanford University, Palo Alto, CA, 2Department of Gastroenterology, The Mount Sinai Hospital, New York, NY, 3Eli Lilly and Company, Indianapolis, IN

    Background/Purpose: Increased incidence of IBD, such as Crohn’s disease (CD) and ulcerative colitis (UC), has been observed in patients (pts) with PsA or plaque psoriasis…
  • Abstract Number: 2514 • 2018 ACR/ARHP Annual Meeting

    Development of a Subcutaneous Formulation of CT-P13 (Infliximab): Maintenance Subcutaneous Administration May Elicit Lower Immunogenicity Compared to Intravenous Treatment

    Dae-Hyun Yoo1, René Westhovens2, S. Ben-Horin3, W. Reinisch4, S. Schreiber5, B.D. Ye6, Sang-Joon Lee7, J.H. Suh7 and M.R. Kim7, 1Department of Rheumatology, Hospital for Rheumatic Diseases Hanyang University, Seoul, Korea, Republic of (South), 2Rheumatology, University Hospital KU Leuven, Leuven, Belgium, 3University of Tel Aviv Sheba Medical Center, Tel-Hashomer, Israel, 4Medical University of Vienna, Vienna, Austria, 5University Hospital Schleswig-Holstein, Kiel, Germany, 6Department of Gastroenterology and Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 7CELLTRION, Inc., Incheon, Korea, Republic of (South)

    Background/Purpose: Intravenous (IV) use of CT-P13, an infliximab (INX) biosimilar, has resulted in comparable efficacy, safety and immunogenicity as innovator INX in various indications including…
  • Abstract Number: 372 • 2017 ACR/ARHP Annual Meeting

    Phenotype of Chronic Recurrent Multifocal Osteomyelitis in a Tertiary Referral Centre: The Great Ormond Street Hospital Experience

    Kulsoom Riaz1 and Sandrine Lacassagne2, 1Paediatric Rheumatology/Gastroenterology, Great Ormond Street Hospital, London, United Kingdom, 2Paediatric Rheumatology, Great Ormond Street Hospital, London, United Kingdom

    Background/Purpose: Recurrent Multifocal Osteomyelitis (CRMO) is an aseptic inflammatory bone disease that typically affects the metaphases of the long bones. It affects children, adolescents and…
  • Abstract Number: 594 • 2017 ACR/ARHP Annual Meeting

    Imaging Biomarkers in Crohn’s Associated Axial Spondyloarthritis

    Fardina Malik1, John A. Carrino2, Madeline Epsten3, Ellen Scherl4, Stephanie Wichuk5, Ulrich Weber6, Susanne J Pedersen7, Joel Paschke8, Jackie Szymonifka3, Georg Kroeber9, Randy Longman4, Walter P. Maksymowych5 and Lisa A. Mandl3, 1Rheumatology, Hospital For Special Surgery, New York, NY, 2Radiology, Hospital for Special Surgery, New York, NY, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Gastroenterology, Weill Cornell Medical College, New York, NY, 5Medicine, University of Alberta, Edmonton, AB, Canada, 6Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, 7Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark, 8CARE Arthritis, Edmonton, AB, Canada, 9University of Southern Denmark, Odense, Denmark

    Background/Purpose: Axial SpA has been reported in 4-16% of patients with Crohn's disease (CD). However, some plain radiograph or magnetic resonance imaging (MRI) studies in…
  • Abstract Number: 1047 • 2017 ACR/ARHP Annual Meeting

    Cost-Effectiveness of Drug-Level Guided Adalimumab Dosing

    Zara Izadi1, Gabriela Schmajuk2, Milena Gianfrancesco3, Laura Trupin4, Kashif Jafri5, Jinoos Yazdany4 and Dhruv Kazi6, 1Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 2San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA, 3Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 4Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, 5University of California, San Francisco, San Francisco, CA, 6Department of Medicine, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA

    Background/Purpose: Adalimumab (ADA) induces and maintains clinical remission in patients with rheumatoid arthritis (RA) and Crohn’s disease (CD) but is an expensive drug. Drug-level and…
  • Abstract Number: 2748 • 2017 ACR/ARHP Annual Meeting

    Immunogenicity of Infliximab Among Patients with Behcet’s Syndrome: A Controlled Study

    Sinem Nihal Esatoglu1, Fatma Nihan Akkoc1, Yesim Ozguler1, Fatma Ozbakir2, Okan Kadir Nohut2, Dilsen Cevirgen3, Vedat Hamuryudan1, Ibrahim Hatemi4, Aykut Ferhat Celik5, Hasan Yazici1 and Gulen Hatemi1, 1Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Istanbul University, Cerrahpasa Medical Faculty, Central Research Laboratory, Istanbul, Turkey, 3Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of and Rheumatology, Istanbul, Turkey, 4Istanbul University, Cerrahpasa Medical School, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, 5Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey

    Background/Purpose: Immunogenicity of anti-TNFs has been recognized as an important problem that may cause loss of response and adverse events such as infusion reactions. We…
  • Abstract Number: 962 • 2016 ACR/ARHP Annual Meeting

    No Increased Risk of Inflammatory Bowel Disease Among Secukinumab-Treated Patients with Moderate to Severe Psoriasis, Psoriatic Arthritis, or Ankylosing Spondylitis: Data from 14 Phase 2 and Phase 3 Clinical Studies

    Atul A. Deodhar1, Stefan Schreiber2, Kunal Gandhi3, Todd Fox4, Corine Gaillez4 and Chetan Karyekar3, 1Oregon Health & Science University, Portland, OR, 2Christian-Albrechts-Universität Kiel, Kiel, Germany, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Novartis Pharma AG, Basel, Switzerland

    Background/Purpose:  Secukinumab, a fully human anti–interleukin-17A monoclonal antibody, has been evaluated and approved for the treatment of moderate to severe psoriasis, active psoriatic arthritis (PsA)…
  • Abstract Number: 1726 • 2016 ACR/ARHP Annual Meeting

    An Integrated Safety Data Analysis Across All Phase II and Phase III Clinical Programs for Ustekinumab in Psoriatic Arthritis, Crohn’s Disease, and Psoriasis

    Lianne S. Gensler1, Elizabeth C. Hsia2, Christopher Gasink2, Bruce Randazzo2, Dennis Parenti3, Steve Fakharzadeh3, Kehzen L. Tang2 and Soumya Chakravarty3, 1Medicine/Rheumatology, UCSF, San Francisco, CA, 2Janssen Research & Development, LLC, Spring House, PA, 3Janssen Scientific Affairs, LLC, Horsham, PA

    Background/Objective:Therapeutic decisions are based on efficacy, but clinicians need to consider medication safety in this process. Here, we report ustekinumab (UST) integrated safety data in…
  • Abstract Number: 906 • 2015 ACR/ARHP Annual Meeting

    Distinct Expression of IL-36α, β, γ and Their Antagonists IL-36Ra and IL-38 in Psoriasis, Rheumatoid Arthritis and Crohn’s Disease

    Marie-Astrid Boutet1, Géraldine Bart2, Jérôme Amiaud1, Bénédicte Brulin3, Céline Charrier3, Franck Morel4, Jean-Claude Lecron4, Malvyne Rolli-Derkinderen5, Arnaud Boureille6, Cem Gabay7, Gaby Palmer8, Benoit Le Goff2 and Frédéric Blanchard9, 1Laboratoire de physiologie de la résorption osseuse, Inserm UMR 957, Nantes, France, 2Rheumatology, Nantes University Hospital, Nantes, France, 3Inserm UMR 957, Nantes, France, 4EA 4331, Poitiers, France, 5Inserm UMR 913, Nantes, France, 6Hepato-Gastroenterology Unit, Nantes University Hospital, Nantes, France, 7Rheumatology, Geneva University Hospital, Geneva, Switzerland, 8Geneva University Hospital, Geneva, Switzerland, 9Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Inserm UMR 957, Nantes, France

    Background/Purpose: The IL-36 family of cytokines comprises three agonists, IL-36α, IL-36β and IL-36g, an antagonist IL-36Ra, as well as IL-38, another potential IL-36 inhibitor. IL-36…
  • Abstract Number: 2061 • 2015 ACR/ARHP Annual Meeting

    Uncovering Crohn’s Disease in Patients with Spondyloarthropathies Using Videocapsule Endoscopy

    Uri Kopylov1, Craig Watts2, Michael Starr3,4, Serge Dionne5, Jamie Koenekoop5 and Ernest Seidman5, 1Gastroenterolog, Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 2Department of Rheumatology, McGill University and Montreal General Hospital, Sainte-Anne-de-Bellevue, QC, Canada, 3Rheumatology, McGill University, Montreal, QC, Canada, 4Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 5Gastroenterology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Inflammatory bowel disease (IBD) is clinically associated with spondylarthropathies (SpA) in 5-15% of cases. Protocol colonoscopic assessment demonstrated asymptomatic inflammation characteristic of Crohn’s disease…
  • Abstract Number: 2284 • 2014 ACR/ARHP Annual Meeting

    Joint Involvement in Pediatric Crohn’s Disease Is Related to Higher Disease Activity and Worse Quality of Life

    Beata Derfalvi1,2, Gabor Bozsaki3, Doloresz Szabo3, Aron Cseh3, Katalin Eszter Muller3, Andras Arato3 and Gabor Veres3, 1Pediatrics, Dalhousie University, Halifax, NS, Canada, 22nd. Dept. of Pediatrics, Semmelweis University, Budapest, Hungary, 31st. Dept. of Pediatrics, Semmelweis University, Budapest, Hungary

    Background/Purpose: The incidence of arthritis and arthralgia in pediatric patients with Crohn's disease (CD) is reported to be 2–15% and 22%, respectively. The aim of our…
  • Abstract Number: 2209 • 2014 ACR/ARHP Annual Meeting

    Novel Biomarkers of Extracellular Matrix Remodeling in Inflammatory Bowel Disease: Different Patterns of Gut Injury in UC and CD

    Joachim Høg Mortensen1, Line Elberg Godskesen2, Michael Dam Jensen2, Lone Gabriels Klinge2, Jens Kjeldsen2, Aleksander Krag2, Morten Karsdal3 and Anne C. Bay-Jensen4, 1Cartilage Biomarkers and Research, Nordic Bioscience, Købehavn, Denmark, 2Odense University Hospital, Odense, Denmark, 3Research & Development, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, 4Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark

     Background/Purpose: About 10 % of patients with IBD have symptoms that match both Crohn's disease (CD) and ulcerative colitis (UC), termed inflammatory bowel disease unclassified…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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