Abstracts tagged "coronary artery disease and rheumatoid arthritis (RA)"

Abstract Number: 499 • 2018 ACR/ARHP Annual Meeting
Low Inflammatory Burden and Statin Exposure Inhibit Progression and Induce Regression of Early Coronary Plaques in Rheumatoid Arthritis
George Karpouzas¹, Sarah Ormseth², Elizabeth Hernandez² and Matthew Budoff³, ¹Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ³Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Early atherosclerotic lesions appear as non-calcified plaques (NCP) on a non-invasive coronary artery evaluation by computed tomography angiography (CCTA). Advanced, more vulnerable lesions appear…
Abstract Number: 501 • 2018 ACR/ARHP Annual Meeting
Predictors of Change in Coronary Plaque Burden and Composition in Patients with Rheumatoid Arthritis
George Karpouzas¹, Sarah Ormseth², Elizabeth Hernandez² and Matthew Budoff³, ¹Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ³Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: We previously reported higher prevalence, burden and more vulnerable occult coronary plaque composition in patients with rheumatoid arthritis (RA) compared to age and gender-matched…
Abstract Number: 502 • 2018 ACR/ARHP Annual Meeting
Implications of Coronary Artery Calcium Score and Its Change over Time As Markers of Coronary Plaque Vulnerability and Patient Risk in Rheumatoid Arthritis
George Karpouzas¹, Sarah Ormseth², Elizabeth Hernandez² and Matthew Budoff³, ¹Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ³Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Atherosclerotic plaque calcification is considered a stabilizing physiologic process; calcified coronary plaques (CP) are less prone to rupture and yield lower risk of cardiovascular…
Abstract Number: 1473 • 2016 ACR/ARHP Annual Meeting
Expression of Vitamin D Receptor Associated Genes in the Aorta of Coronary Artery Disease Patients with and without Rheumatoid Arthritis
Ingvild Oma¹, Sverre Holm^2,3, Jacqueline Kirsti Andersen⁴, Ole K. Olstad⁵, Ida G. Fostad⁶, Torstein Lyberg⁵, Sven Martin Almdahl⁷, Øyvind Molberg⁸ and Ivana Hollan^9,10,11, ¹Innlandet Hospital Trust, Lillehammer, Norway, ²Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, ³Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁴Norwegian University of Science and Technology, Gjøvik, Norway, ⁵Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, ⁶Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway, ⁷Department of Cardiothoracic Surgery, University Hospital of North Norway, Tromsø, Norway, ⁸Oslo University Hospital, Oslo, Norway, ⁹Brigham and Women’s Hospital, Boston, MA, ¹⁰Harvard Medical School, Boston, MA, ¹¹Lillehammer Hospital for Rheumatic Diseases, Lillahammer, Norway
Background/Purpose: Vitamin D has an important role in the immune system, and has been linked to inflammation, rheumatoid arthritis (RA) and coronary artery disease (CAD)[1,…
Abstract Number: 1478 • 2016 ACR/ARHP Annual Meeting
Coronary Artery Calcification in Rheumatoid Arthritis Patients Is Not Characterized By an Increase in Genes Associated with Coronary Artery Disease in the General Population
Ivan Ferraz-Amaro¹, Robert Winchester², Peter K. Gregersen³, Richard J. Reynolds⁴, Annette M. Oeser⁵, Cecilia P. Chung⁶, C. Michael Stein⁶, Mary Chester M. Wasko⁷, Jon T. Giles⁸ and Joan Bathon², ¹Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ²Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Med Res, Manhasset, NY, ⁴Medicine, University of Alabama at Birmingham, Birmingham, AL, ⁵Vanderbilt University Medical Center, Nashville, TN, ⁶Medicine, Vanderbilt University Medical Center, Nashville, TN, ⁷Lupus Center, Pittsburgh, PA, ⁸Rheumatology, Columbia University Medical Center, NY, NY
Background/Purpose: In the general population individuals with coronary artery disease (CAD) have a significantly increased frequency of particular susceptibility single nucleotide polymorphisms (SNPs). Since CAD…
Abstract Number: 1483 • 2016 ACR/ARHP Annual Meeting
Elevated Anti-Cyclic Citrullinated Peptide Antibody Titer Is Associated with Increased Cardiovascular Risk
Sarah A. Fantus¹, Melissa R. Bussey², Rochella A. Ostrowski³, Andrew Heisler¹ and Kyle Carey⁴, ¹Internal Medicine, Loyola University Medical Center, Maywood, IL, ²Division of Allergy, Immunology, and Rheumatology, Loyola University Medical Center, Maywood, IL, ³Rheumatology, Loyola University Medical Center, Maywood, IL, ⁴Clinical Research Office, Loyola University Chicago, Maywood, IL
Background/Purpose: Rheumatoid arthritits (RA) patients have an increased risk of mortality from cardiovascular (CV) disease. Proposed adaptation of CV risk score models in RA patients…
Abstract Number: 1594 • 2015 ACR/ARHP Annual Meeting
No Association of Anti-Citrullinated Peptide Antibodies with Coronary Artery Calcification in Two Rheumatoid Arthritis Cohorts without Clinical Cardiovascular Disease
Laura Geraldino-Pardilla¹, Jon T. Giles², Jeremy Sokolove³, Afshin Zartoshti⁴, WH Robinson⁵ and Joan M. Bathon⁶, ¹Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Medicine, VA Palo Alto HealthCare System and Stanford University, Palo Alto, CA, ⁴Rheumatology, Columbia University Medical Center, NY, NY, ⁵Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁶Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Background/Purpose: Citrullinated proteins have been found in atherosclerotic plaques. However, contradictory results currently exist regarding the association of anti-citrullinated peptide antibodies (ACPAs) with coronary artery…
Abstract Number: 2501 • 2015 ACR/ARHP Annual Meeting
Determining the Rate of Cardiovascular Risk Assessment in Patients with Rheumatoid Arthritis at Federally Qualified Outpatient Continuity Clinic – a Performance Improvement Project
Dewan Fahima¹ and Rafah Salloum², ¹Internal Medicine, Monmouth Medical Center, Long Branch, NJ, ²Rheumatology, Monmouth Medical Center, Long Branch, NJ
Background/Purpose: Studies have shown patients with rheumatoid arthritis (RA), a chronic inflammatory condition, have accelerated rate of coronary artery and cerebrovascular disease. Patients with RA,…
Abstract Number: 1376 • 2014 ACR/ARHP Annual Meeting
Angiographic Pattern Among Rheumatoid Arthritis Patients Who Are Hospitalized Due to Acute Coronary Syndrome
Marie Holmqvist¹, Ängla Mantel², Tomas Jernberg³, Stefan James⁴, Solveig Wållberg-Jonsson⁵ and Johan Askling⁶, ¹Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, ²Dept of Medicine, Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Solna, Sweden, ³Department of medicine, Section of Cardiology, Karolinska University Hospital, Stockholm, Sweden, ⁴3Department of Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden, ⁵Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, ⁶Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: We aimed at investigating and to compare the angiographic pattern of stenoses in patients with rheumatoid arthritis (RA) and general population comparators hospitalized due…
Abstract Number: 1664 • 2012 ACR/ARHP Annual Meeting
Autoantibodies Are Associated with Subclinical Atherosclerosis and Cardiovascular Endpoints in Caucasian and African American Women in a Prospective Study: the Multi-Ethnic Study of Atherosclerosis (MESA)
Darcy S. Majka¹, Rowland W. Chang², Richard M. Pope³, Marius C. Teodorescu⁴, Elizabeth W. Karlson⁵, Thanh Huyen T. Vu⁶, Joseph Kang⁶ and Kiang Liu⁷, ¹Division of Rheumatology, Northwestern University, Chicago, IL, ²Dept Preventive Med, Northwestern University, Chicago, IL, ³Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL, ⁴Microbiology, TheraTest Laboratories Inc, Lombard, IL, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁶Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, ⁷Preventive Medicine, Northwestern University, Chicago, IL
Background/Purpose: Although the association between rheumatoid arthritis (RA) and cardiovascular disease (CVD) is established, the exact mechanism is not known. Subjects who later develop RA…
Abstract Number: 1260 • 2012 ACR/ARHP Annual Meeting
Hydroxychloroquine Reduces the Risk of Coronary Artery Disease in Patients with Rheumatoid Arthritis
Li Chun¹, Mu Rong¹, Su Yin¹, Li Xiaofeng², Wang Yongfu³, Wang Guochun⁴, Zhu Ping⁵, Liu Xiangyuan⁶, Chen Haiying⁷, Cui Liufu⁸, Zhang Zhuoli⁹, Li Zhenbin¹⁰, Li Junfang¹¹, Zhang Fengxiao¹², Han Shuling¹³, Lin Jinying¹⁴, Liu Xiaomin¹⁵, Hu Shaoxian¹⁶, Yang Xiuyan¹⁷, Huang Cibo Sr.¹⁸, Li Xingfu¹⁹, Wang Yi²⁰ and Li Zhanguo¹, ¹Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China, ²Department of Rheumatology and Immunology, Taiyuan, China, ³Department of Rheumatology and Immunology, Baotou, China, ⁴Department of Rheumatology and Immunology, Beijing, China, ⁵Department of Rheumatology and Immunology,Xijing Hospital, Xian, China, ⁶Department of Rheumatology and Immunology,Peking University Third Hospital, Beijing, China, ⁷Department of Rheumatology and Immunology,The Third Hospital of, Shijiazhuang, China, ⁸Department of Rheumatology and Immunology,Kailuan hospital of North China Coal Hospital, Tangshan, China, ⁹Department of Rheumatology and Immunology,Peking University First Hospital, Beijing, China, ¹⁰Department of Rheumatology and Immunology,Peace Hospital, Shijiazhuang, China, ¹¹Department of Rheumatology and Immunology, Hebei Handan Central Hospital, Handan, China, ¹²Department of Rheumatology and Immunology,Hebei People's Hospital, China, ¹³Department of Rheumatology and Immunology, Peking University Shougang Hospital, Beijing, China, ¹⁴Department of Rheumatology and Immunology,The people's hospital of guangxi zhuang autonomous region, Nanning, China, ¹⁵Department of Rheumatology and Immunology,Beijing shunyi hospital of China Medical University, Beijing, China, ¹⁶Department of Rheumatology and Immunology,Tongji Medical College Huazhong University of Science & Technology, Wuhan, China, ¹⁷Department of Rheumatology and Immunology,First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ¹⁸Rheumatology and Immunology Department, Beijing Hospital, Ministry of Health, Beijing, China, ¹⁹.Department of Rheumatology and Immunology,Qilu Hospital of Shandong University, Jinan, China, ²⁰Department of Rheumatology and Immunology,Second hospital of Lanzhou University, Lanzhou, China
Background/Purpose: Disease modifying anti-rheumatic drugs (DMARDs) can alter cardiovascular risk in RA by inflammation or by influencing cardiovascular risk factors indirectly. However, previous studies predominantly…
Abstract Number: 1250 • 2012 ACR/ARHP Annual Meeting
Heightened Aortic Wall Inflammation in Patients with Rheumatoid Arthritis Versus Patients with Established Coronary Artery Disease without Autoimmune Disease
Jeffrey D. Greenberg¹, Zahi Fayad², Victoria Furer³, Michael Farkouh², Michael J. Colin⁴, Pamela B. Rosenthal⁵, Jonathan Samuels⁵, Svetlana Krasnokutsky Samuels⁴, Soumya M. Reddy⁶, Peter M. Izmirly⁵, Cheongeun Oh⁷, Manish Jain⁵ and Venkatesh Mani², ¹New York Hospital for Joint Disease, New York, NY, ²Mount Sinai School of Medicine, New York, NY, ³Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, ⁴NYU School of Medicine, New York, NY, ⁵Rheumatology, NYU School of Medicine, New York, NY, ⁶Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁷Biostatistics, NYU School of Medicine, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) has been associated with premature atherosclerosis and increased prevalence of cardiovascular disease. 18-fluoro-deoxyglucose positron emission tomography (18-FDG-PET) is a promising imaging…
Abstract Number: 68 • 2012 ACR/ARHP Annual Meeting
Cardiovascular Comorbidities Antedating the Diagnosis of Rheumatoid Arthritis
Anne M. Kerola¹, Tuomas Kerola², Markku J. Kauppi², Hannu Kautiainen³, Lauri J. Virta⁴, Kari Puolakka⁵ and Tuomo Nieminen⁶, ¹Medical School, University of Helsinki, Helsinki, Finland, ²Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, ³Unit of Primary Health Care, Kuopio University Hospital, Kuopio, Finland, ⁴Research Department, the Social Insurance Institution, Turku, Finland, ⁵Department of Medicine, South Karelia Central Hospital, Lappeenranta, Finland, ⁶Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular morbidity. Evidence suggests that RA patients are at an increased risk of…

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