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Abstracts tagged "complement"

  • Abstract Number: 542 • 2013 ACR/ARHP Annual Meeting

    Evidence For Involvement Of C5a Receptor in Human and Murine Lupus Nephritis

    Constanze Hess1, Ditte Tornehave2, Peter Helding Kvist2, Yvonne Sundström3, Louise Berg3, Iva Gunnarsson4, Søren Jacobsen5, Claus Haase1 and Lars Hornum1, 1Department of Immunopharmacology, Novo Nordisk A/S, Måløv, Denmark, 2Department of Histology, Novo Nordisk A/S, Måløv, Denmark, 3Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 4Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 5Department of Rheumatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

    Background/Purpose: The complement system plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Apart from the activation of the early components of…
  • Abstract Number: 20 • 2013 ACR/ARHP Annual Meeting

    Complement Deposition On Platelets Is Associated To Venous Thrombosis In Systemic Lupus Erythematosus

    Christian Lood1, Helena Tydén1, Birgitta Gullstrand2, Gunnar Sturfelt3, Andreas Jönsen1, Lennart Truedsson2 and Anders A. Bengtsson1, 1Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, 2Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden, 3Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden

    Background/Purpose: Anti-phospholipid (aPL) antibodies are associated with development of venous thrombosis and stroke in the autoimmune disease systemic lupus erythematosus (SLE). The underlying mechanism for…
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ACR Pediatric Rheumatology Symposium 2020

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