ACR Meeting Abstracts

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Abstracts tagged "Cohort Study"

  • Abstract Number: 1267 • ACR Convergence 2020

    Perceived Stress During the COVID-19 Pandemic Independently Associates with Worse Patient-Reported Outcomes in Systemic Lupus Erythematosus (SLE)

    Sarah Patterson1, Laura Trupin2, Kimberly DeQuattro1, Cristina Lanata1, Maria Dall'Era3, Jinoos Yazdany2 and Patricia Katz2, 1UCSF, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3Division of Rheumatology, University of California, San Francisco, CA

    Background/Purpose: Causes and risk factors for variations in SLE disease activity and symptom severity are incompletely understood. Prior studies suggest a link between stressful life…
  • Abstract Number: 1737 • ACR Convergence 2020

    What Influences Fatigue Improvement in Rheumatoid Arthritis? A Prospective Cohort Study

    Samar Aboulenain1, Elie Donath1 and Ozlem Pala2, 1University of Miami Miller School, West Palm Beach, FL, 2University of Miami Miller School, Fort Lauderdale, FL

    Background/Purpose: Fatigue is a common and debilitating complication in patients with rheumatoid arthritis (RA). Its mechanism is not fully elucidated, and when persistent is often…
  • Abstract Number: 0391 • ACR Convergence 2020

    Defining the Optimal Disease Duration of Early Diffuse Systemic Sclerosis for Clinical Trial Design

    Robyn Domsic1, Shiyao Gao2, Maureen Laffoon2, Steven Wisniewski3, Yuqing Zhang4, Robert Lafyatis5, Virginia Steen6 and Thomas Medsger7, 1University of Pittsburgh School of Medicine, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 4Massachusetts General Hospital, Harvard Medical School, Boston, 5University of Pittsburgh, Arlington, MA, 6Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, 7University of Pittsburgh School of Medicine, Verona, PA

    Background/Purpose: Clinical trials in early diffuse cutaneous systemic sclerosis (SSc) have historically used the modified Rodnan skin score (mRSS) as the primary outcome measure.  These…
  • Abstract Number: 0869 • ACR Convergence 2020

    Retinal Toxicity in a Multinational Inception Cohort of Systemic Lupus Patients on Hydroxychloroquine

    Celline Almeida-Brasil1, John Hanly2, Murray Urowitz3, Ann Clarke4, Rosalind Ramsey-Goldman5, Caroline Gordon6, Michelle Petri7, Ellen M Ginzler8, Daniel J Wallace9, Sang-Cheol Bae10, Juanita Romero-Díaz11, Mary Ann Dooley12, Christine A. Peschken13, David Isenberg14, Anisur Rahman14, Susan Manzi15, Søren Jacobsen16, S. Sam Lim17, Ronald Van Vollenhoven18, Ola Nived19, Andreas Jönsen19, Diane Kamen20, Cynthia Aranow21, Guillermo Ruiz-Irastorza22, Jorge Sanchez-Guerrero23, Dafna Gladman24, Paul Fortin25, Graciela Alarcón26, Joan Merrill27, Kenneth Kalunian28, Manuel Ramos-Casals29, Kristjan Steinsson30, Asad Zoma31, Anca Askanase32, Munther Khamashta33, Ian Bruce34, Murat Inanc35 and Sasha Bernatsky36, 1McGill University, Montreal, Canada, 2QEII Health Sciences Centre, Halifax, Canada, 3University Health Network, University of Toronto, Toronto, ON, Canada, 4University of Calgary, Calgary, Canada, 5Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6University of Birmingham, Birmingham, England, United Kingdom, 7Johns Hopkins University School of Medicine, Baltimore, 8SUNY Downstate Health Sciences University, Brooklyn, 9Cedars-Sinai Medical Center, Beverly Hills, CA, 10Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 11Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, 12UNC Health, Chapel Hil, 13University of Manitoba, Winnipeg, Canada, 14University College London, London, United Kingdom, 15Temple University, Philadelphia, 16University of Copenhagen, Copenhagen, Denmark, 17Emory University, Atlanta, GA, 18University of Amsterdam, Amsterdam, Netherlands, 19Lund University, Lund, Sweden, 20Medical University of South Carolina, Charleston, SC, 21Feinstein Institutes for Medical Research, Manhasset, NY, 22Hospital Universitario Cruces, Barakaldo, Spain, 23University of Toronto, Toronto, Canada, 24Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 25CHU de Quebec - Universite Laval, Quebec, Canada, 26Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham; Department of Medicine, School of Medicine; Universidad Peruana Cayetano, Heredia, Alabama, 27New York University, New York, 28University of California San Diego, La Jolla, CA, 29University of Barcelona, Barcelona, Spain, 30Reykjavik University, Reykjavik, Iceland, 31University of Glasgow, Glasgow, United Kingdom, 32Columbia University College of Physicians & Surgeons, New York, NY, 33King's College London, London, United Kingdom, 34The University of Manchester, Manchester, United Kingdom, 35Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, 36The Research Institute of the McGill University Health Centre, Montreal, ON, Canada

    Background/Purpose: Despite the beneficial effects of hydroxychloroquine (HCQ) in systemic lupus erythematosus (SLE), retinal toxicity is a concern. Factors associated with retinal toxicity have been…
  • Abstract Number: 1280 • ACR Convergence 2020

    COVID-19 Infections May Increase the Risk of SLE Flares

    Leila Khalili1, Yevgeniya Gartshteyn2, Nancyanne Schmidt3, Teja Kapoor4, Laura Geraldino-Pardilla5 and Anca Askanase3, 1Columbia University Medical Center, New York, NY, 2Columbia University College of Physicians and Surgeons, Glen Rock, NJ, 3Columbia University College of Physicians and Surgeons, New York, NY, 4Columbia University College of Physicians and Surgeons, Leonia, NJ, 5Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York

    Background/Purpose: COVID-19 has overwhelmed the healthcare systems in New York City. Initial data from the Columbia Lupus Cohort suggests that 4% of patients with systemic…
  • Abstract Number: 1738 • ACR Convergence 2020

    Promote Treat-to-Target for RA via Empowering Patients: A Cohort Study from China by Smart System of Disease Management (SSDM)

    Jing Yang1, Rong Mu2, Chun Li3, Bin Wu4, Hongzhi Wang5, Wenqiang Fan6, Jinmei Zou7, Yu Zhang1, Fen Li8, Xiaofeng Rong9, Jianhong Wu10, Yong Wang11, Shengguang Li12, Yi Zhao13, Xiaoqiang Hou14, Hui Xiao15, Yuhua Jia16, Bing Wu16, Miaomiao Song16, Fei Xiao16 and Zhanguo Li17, 1Department of Rheumatology, Mianyang Central Hospital, Mianyang, China (People's Republic), 2People's Hospital, Beijing University Medical School, Beijing, Beijing, China (People's Republic), 3People's Hospital, Beijing University Medical School, beijing, China (People's Republic), 4Chongqing Hospital of Traditional Chinese Medicine, chongqing, China (People's Republic), 5The First Hospital of Jiaxing, Jiaxing, China (People's Republic), 6Central Hospital of XinXiang, Xinxiang, China (People's Republic), 7Department of Rheumatology, Mianyang Central Hospital, Mianyang, Sichuan, China (People's Republic), 8The Second Xiangya Hospital of Central South University, hunan, China (People's Republic), 9The First Affiliated Hospital of Chongqing Medical University, chongqing, China (People's Republic), 10Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 11The first Hospital Affiliated to AMU (Southernwest Hospital), chongqing, China (People's Republic), 12Peking University International Hospital, Beijing, China (People's Republic), 13Xuanwu Hospital, Capital Medical University, Beijing, China, Beijing, China (People's Republic), 14Yichang Central People's Hospital, Beijing, China (People's Republic), 15Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 16Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 17Peking University People’s Hospital, Xicheng, Beijing, China (People's Republic)

    Background/Purpose: Treat-to-Target (T2T) strategy are critical for the treatment of RA, but Chinese rheumatologists can hardly provide patients with a complete assessment in the clinic…
  • Abstract Number: 0416 • ACR Convergence 2020

    IgG4-related Retroperitoneal Fibrosis. Retrospective Cohort

    Ernestina Angarola1, Federico Jauk2, Verónica Peuchot3, Maria Orlova1, Melina Valeo2, Javier Pollan1 and Hernán Garcia Rivello2, 1Department of Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 2Department of Pathology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 3Internal Medicine Research Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina

    Background/Purpose: The spectrum of IgG4-related disease (IgG4-RD) includes many diseases that were thought to be confined to a single organ, as the retroperitoneal fibrosis. Many…
  • Abstract Number: 0937 • ACR Convergence 2020

    Late Cardiovascular Outcomes in Children with Kawasaki Disease: A Population-based Cohort Study

    Cal Robinson1, Rahul Chanchlani1, Anastasia Gayowsky2, Sandeep Brar3, Elizabeth Darling4, Catherine Demers4, Tapas Mondal1, Rulan Parekh5, Hsien Seow4 and Michelle Batthish1, 1McMaster Children's Hospital, Hamilton, ON, Canada, 2ICES McMaster, Hamilton, ON, Canada, 3University of California, San Fransisco, 4McMaster University, Hamilton, ON, Canada, 5University of Toronto, Toronto, Canada

    Background/Purpose: Kawasaki disease (KD) is a common childhood vasculitis associated with coronary artery aneurysms (CAA). Based on our recent work, the incidence of KD has…
  • Abstract Number: 1304 • ACR Convergence 2020

    Uveitis Occurrence in Early Inflammatory Back Pain: Five Years Data from a Prospective French Nationwide Cohort

    Daniel Wendling1, Clement Prati2, Thierry Lequerre3, Corinne Miceli-Richard4, Maxime Dougados5, Anna Molto6 and Xavier Guillot7, 1CHU Besançon, department of rheumatology, Besancon, France, 2Rheumatology, University Teaching Hospital, Besançon, France, 3Rheumatology, University Teaching Hospital, Rouen, France, 4Paris Descartes University, Department of Rheumatology - Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, 5Department of Rheumatology, Hopital Cochin, Université de Paris, Paris, France, 6Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France, 7CHU Reunion, Saint Denis, Reunion

    Background/Purpose: Uveitis is the most frequent extra rheumatological manifestation in axial Spondyloarthritis (SpA). DESIR is a prospective multicenter cohort of patients with early inflammatory back…
  • Abstract Number: 1837 • ACR Convergence 2020

    Clinical Outcomes in Lupus Nephritis by Renal Response Status: A Retrospective Analysis of the Hopkins Lupus Cohort

    Michelle Petri1, Qinggong Fu2, Yulia Green3, Anuradha Madan4, Daniel Goldman5 and Selin Cooper-Blenkinsopp6, 1Johns Hopkins University School of Medicine, Baltimore, 2GlaxoSmithKline, Upper Providence, 3GlaxoSmithKline, Uxbridge, 4GlaxoSmithKline, Collegeville, 5Johns Hopkins University School of Medicine, Timonium, MD, 6GlaxoSmithKline, Stevenage, United Kingdom

    Background/Purpose: A retrospective analysis of the Hopkins Lupus Cohort (a prospective, longitudinal study of patients [pts] with systemic lupus erythematosus) reported that renal response (complete/partial/none)…
  • Abstract Number: 0475 • ACR Convergence 2020

    To Attend or Note to Attend; The Medical Student’s Dilemma

    Benjamin Widener1, Amy Cannella1 and Sarah McBrien1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: We present a comparison of student’s outcomes with remote video-based learning versus lecture attendance in pre-clinical medical students during a musculoskeletal curriculum, thus allowing…
  • Abstract Number: 1001 • ACR Convergence 2020

    Risk of Malignant Melanoma and Nonmelanoma Skin Cancer in Rheumatoid Arthritis Patients Initiating Methotrexate versus Hydroxychloroquine

    Hemin Lee1, Sarah Chen2, Nileesa Gautam2, Seanna Vine1, Mengdong He2, Rishi Desai2, Michael Weinblatt1, Robert Glynn2 and Seoyoung Kim2, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston

    Background/Purpose: Previous randomized clinical trials and observational studies have signaled an increased risk of skin cancer in rheumatoid arthritis (RA) patients treated with immunosuppressants such…
  • Abstract Number: 1325 • ACR Convergence 2020

    Monoclonal Gammopathy in Psoriatic Arthritis

    Vanessa Ocampo1 and Dafna Gladman2, 1University of Toronto, University Health Network, Psoriatic Arthritis Research Program, Toronto, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant clonal plasma disorder, defined by the presence of a serum monoclonal protein (M-protein) at…
  • Abstract Number: 1841 • ACR Convergence 2020

    Outcomes After Hydroxychloroquine Reduction or Discontinuation in a Multinational Inception Cohort of Systemic Lupus

    Celline Almeida-Brasil1, John Hanly2, Murray Urowitz3, Ann Clarke4, Rosalind Ramsey-Goldman5, Caroline Gordon6, Michelle Petri7, Ellen M Ginzler8, Daniel J Wallace9, Sang-Cheol Bae10, Juanita Romero-Diaz11, Mary Ann Dooley12, Christine A. Peschken13, David Isenberg14, Anisur Rahman14, Susan Manzi15, Søren Jacobsen16, S. Sam Lim17, Ronald Van Vollenhoven18, Ola Nived19, Andreas Jönsen19, Diane Kamen20, Cynthia Aranow21, Guillermo Ruiz-Irastorza22, Jorge Sanchez-Guerrero23, Dafna Gladman24, Paul Fortin25, Graciela Alarcón26, Joan Merrill27, Kenneth Kalunian28, Manuel Ramos-Casals29, Kristjan Steinsson30, Asad Zoma31, Anca Askanase32, Munther Khamashta33, Ian Bruce34, Murat Inanc35 and Sasha Bernatsky36, 1McGill University, Montreal, Canada, 2QEII Health Sciences Centre, Halifax, Canada, 3University Health Network, University of Toronto, Toronto, ON, Canada, 4University of Calgary, Calgary, Canada, 5Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6University of Birmingham, Birmingham, England, United Kingdom, 7Johns Hopkins University School of Medicine, Baltimore, 8SUNY Downstate Health Sciences University, Brooklyn, 9Cedars-Sinai Medical Center, Beverly Hills, CA, 10Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 11Salvador Zubirán National Institute of Health Sciences and Nutrition, Mexico City, Mexico, 12UNC Health, Chapel Hil, 13University of Manitoba, Winnipeg, Canada, 14University College London, London, United Kingdom, 15Temple University, Philadelphia, 16University of Copenhagen, Copenhagen, Denmark, 17Emory University, Atlanta, GA, 18University of Amsterdam, Amsterdam, Netherlands, 19Lund University, Lund, Sweden, 20Medical University of South Carolina, Charleston, SC, 21Feinstein Institutes for Medical Research, Manhasset, NY, 22Hospital Universitario Cruces, Bizkaia, Spain, 23University of Toronto, Toronto, Canada, 24Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 25CHU de Quebec - Universite Laval, Quebec, Canada, 26Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham; Department of Medicine, School of Medicine; Universidad Peruana Cayetano, Heredia, Alabama, 27New York University, New York, 28University of California San Diego, La Jolla, CA, 29University of Barcelona, Barcelona, Spain, 30Reykjavik University, Reykjavik, Iceland, 31University of Glasgow, Glasgow, United Kingdom, 32Columbia University College of Physicians & Surgeons, New York, NY, 33King's College London, London, United Kingdom, 34The University of Manchester, Manchester, United Kingdom, 35Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, 36The Research Institute of the McGill University Health Centre, Montreal, ON, Canada

    Background/Purpose: Hydroxychloroquine (HCQ) is a cornerstone treatment for several autoimmune diseases including Systemic Lupus Erythematosus (SLE). Recently, concerns arose regarding HCQ shortages for SLE patients,…
  • Abstract Number: 0503 • ACR Convergence 2020

    Targeted Metabolomic Profiling and Prediction of Cardiovascular Events: A Prospective Study of Patients with Psoriatic Arthritis and Psoriasis

    Keith Colaco1, Ker-Ai Lee2, Shadi Akhtari3, Raz Winer4, Paul Welsh5, Naveed Sattar5, Iain McInnes6, Vinod Chandran7, Paula Harvey8, Richard Cook2, Dafna Gladman7, Vincent Piguet8 and Lihi Eder9, 1Institute of Medical Science, University of Toronto; Women's College Research Institute, Women's College Hospital; and Toronto Western Hospital, University Health Network, Toronto, ON, Canada, 2University of Waterloo, Waterloo, ON, Canada, 3Women's College Hospital, University of Toronto, North York, ON, Canada, 4Rambam Health Care Campus, Haifa, Israel, 5University of Glasgow, Glasgow, Scotland, United Kingdom, 6Institute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, United Kingdom, 7Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 8Women's College Hospital, University of Toronto, Toronto, ON, Canada, 9Women’s College Research Institute, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Psoriatic arthritis and psoriasis, collectively termed psoriatic disease (PsD), are associated with increased cardiovascular (CV) risk. Metabolites comprise biomarkers that may add predictive value…
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