Abstracts tagged "Cohort Study"

Abstract Number: 1932 • ACR Convergence 2025
Evaluating a Potential Cause of Excess Lung Cancer Mortality in RA: An Analysis of Chest CT Imaging Frequency in RA
Rebecca Brooks¹, Sara Achenbach², Vanessa Kronzer¹, Bryant England³, Emily Leasure¹, Elena myasoedova¹, John Davis¹ and Cynthia Crowson⁴, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Rochester, ³University of Nebraska Medical Center, Omaha, NE, ⁴Mayo Clinic, Stewartvillle, MN
Background/Purpose: Recent studies have demonstrated that patients with RA are at an increased risk for the development of lung cancer and lung cancer related death.…
Abstract Number: 1505 • ACR Convergence 2025
Discordance Between Physician and Patient Global Assessment of Disease Activity in a Large Multicenter Prospective SLE Cohort in the U.S. and Canada
Romy Kallas¹, Naiva Manuela Piatchou Donfack¹, Deanna Jannat-Khah¹, Cynthia Aranow², Cristina Arriens³, Jill Buyon⁴, Megan Clowse⁵, Maria Dall'Era⁶, Richard Furie⁷, Ellen Ginzler⁸, Jennifer Grossman⁹, Kenneth Kalunian¹⁰, Diane Kamen¹¹, Kichul Ko¹², William McCune¹³, Brad Rovin¹⁴, Francisco Sanchez-Guerrero¹⁵, Saira Sheikh¹⁶, Kyriakos Kirou¹ and Timothy Niewold¹⁷, ¹Hospital for Special Surgery, New York, NY, ²Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, NY, ³Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴NYU Grossman School of Medicine, New York, NY, ⁵Duke University, Chapel Hill, NC, ⁶Division of Rheumatology, University of California, San Francisco, CA, ⁷Division of Rheumatology, Northwell Health, Great Neck, NY, ⁸SUNY Downstate Health Sciences University, New York, NY, ⁹UCLA, Sherman Oaks, CA, ¹⁰UC San Diego, La Jolla, CA, ¹¹Medical University of South Carolina, Johns Island, SC, ¹²The University of Chicago, Chicago, IL, ¹³U Michigan, Ann Arbor, MI, ¹⁴The Ohio State University, Columbus, OH, ¹⁵University Health Network/Sinai Health system, Toronto, ON, Canada, ¹⁶University of North Carolina at Chapel Hill, Chapel Hill, NC, ¹⁷Hospital for Special Surgery, New York, New York
Background/Purpose: Understanding the discordance between patient- and physician-reported disease assessment scores is essential for incorporating patient-reported outcomes into disease activity measures and identifying gaps between…
Abstract Number: 1415 • ACR Convergence 2025
The Association of Handedness with Radiographic Damage in Patients with Psoriatic Arthritis
Fadi Kharouf¹, Shahad Al-Matar², Virginia Carrizo Abarza³, Pankti Mehta⁴, Shangyi Gao⁵, Daniel Pereira⁶, Richard Cook⁷, Vinod Chandran⁸, Denis Poddubnyy⁹ and Dafna D. Gladman¹⁰, ¹University Health Network and University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, ²University of alberta, Edmonton, AB, Canada, ³Toronto Western Hospital - University of Toronto, Toronto, ON, Canada, ⁴University of Toronto, Gladman Krembil Psoriatic Arthritis Research Program, Toronto, ON, Canada, ⁵Gladman-Krembil Psoriatic Arthritis Research Program, Centre for Prognosis Studies in the Rheumatic Diseases, Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada, Toronto, ON, Canada, ⁶University Health Network, Toronto, ON, Canada, ⁷University of Waterloo, Waterloo, Canada, ⁸University of Toronto, Toronto, ON, Canada, ⁹Division of Rheumatology, Department of Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada, and Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany; Department of Epidemiology, German Rheumatism Research Centre, Berlin, Germany, ¹⁰Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada
Background/Purpose: Mechanical stress is known to trigger and exacerbate psoriatic arthritis (PsA). Based on the hypothesis that biomechanical stress is greater in the dominant extremity,…
Abstract Number: 1118 • ACR Convergence 2025
Increased Risk of Azathioprine-Induced Leukopenia in Patients with Systemic Lupus Erythematosus: A 10-Year Retrospective Cohort Study at a Quaternary Care Hospital in Thailand
Settawut Buadee¹, Kittikorn Wilasrusmee¹, Tanakrit Kamonsumlitpon¹, Sirirat Charuvanij², Ekapun Karoopongse³ and Praveena Chiowchanwisawakit⁴, ¹Medical Student, Faculty of Medicine, Siriraj Hospital, Mahdol University, Bangkok, Thailand, ²Division of Rheumatology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand, ³Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand, ⁴Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand
Background/Purpose: To estimate the incidence and identify associated factors of azathioprine (AZA)-induced leukopenia.Methods: A retrospective cohort study was conducted on 1,062 adult patients with non-malignant…
Abstract Number: 0605 • ACR Convergence 2025
The Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) Predicts Worsening Self-Efficacy in the Patients from the Almenara Lupus Cohort
Anubhav Singh¹, Rocío Gamboa-Cárdenas², Victor Pimentel-Quiroz³, Zoila Rodriguez-Bellido⁴, Cesar Pastor-Asurza⁵, Risto Perich-Campos⁶, Manuel Ugarte-Gil⁷ and Graciela Alarcón⁸, ¹Baptist hospital of southeast Texas, Beaumont, TX, ²Universidad Científica del Sur, Lima, Peru, ³Universidad Científica del Sur, San Isidro, Peru, ⁴Universidad Nacional Mayor de San Marcos, Lima, Peru, ⁵Hospital Nacional Guillermo Almenara Irigoyen, Lima, Pakistan, ⁶Hospital Nacional Guillermo Almenara Irigoyen; Universidad Nacional Mayor de San Marcos, La Molina, Peru, ⁷Universidad Cientifica del Sur, Lima, Peru, ⁸The University of Alabama at Birmingham, Oakland, CA
Background/Purpose: The Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) was developed to ascertain frailty in systemic lupus erythematosus (SLE) patients. The aim of this…
Abstract Number: 0439 • ACR Convergence 2025
Osteoarthritis and Other Degenerative Musculoskeletal Disorders Are Common and Often Associated with Active Inflammation in Difficult-to-Treat Rheumatoid Arthritis: A Cross-Sectional Cohort
Blanche QUERE¹, Grégoire CORMIER², LE GOFF Benoit³ and Adrien LE PLUART⁴, ¹CHU de Nantes, Nantes, Pays de la Loire, France, ²Centre Hospitalier département de Vendée, La Roche Sur Yon, France, ³CHU Nantes, Nantes, France, ⁴CHU Nantes, Nantes, Pays de la Loire, France
Background/Purpose: Despite advances in therapeutic strategies, a subset of patients with rheumatoid arthritis (RA) continues to experience persistent symptoms. In 2022, the EULAR proposed a…
Abstract Number: 0180 • ACR Convergence 2025
Digital Transformation in IMID Care: Results from the Implementation of IMIDOC
JOSE INIESTA-CHAMORRO¹, Marta Novella-Navarro², Diego Benavent³, HELENA BORREL-PAÑOS⁴, Xabier Michelena Vegas⁵, Javier Bachiller⁶, Verónica García García⁷, ESTHER ESPARTAL⁴, LETICIA LOJO-OLIVEIRA⁸, Enrique Calvo-Aranda⁹, José Rodríguez gago¹⁰, Gema Bonilla¹¹, Irene Monjo Henry², Victoria Navarro-Compan¹², Jaime Arroyo¹⁰, Eugenio de Miguel², Mariana Díaz-Almirón¹³, cARMEN ALEGRE¹⁰, ENRIQUE J GÓMEZ¹⁴ and Chamaida Plasencia-Rodríguez², ¹¹Biomedical Engineering and Telemedicine Centre, ETSIT, Center for Biomedical Technology, Universidad Politéctica de Madrid, TELEMEDICINE, MADRID, ²Hospital Universitario La Paz, Madrid, Spain, ³Hospital Universitari de Bellvitge, Madrid, Spain, ⁴⁴HOSPITAL UNIVERSITARIO VALL D´HEBRON, RHEUMATOLOGY, BARCELONA, Spain,, BARCELONA, ⁵Hospital Universitari Vall Hebron, Barcelona, Spain, ⁶Hospital Ramon y Cajal, Madrid, Madrid, Spain, ⁷Ramón y Cajal University Hospital, MADRID, Spain, ⁸Hospital Universitario Infanta Leonor, Madrid, Spain, ⁹Department of Rheumatology, Hospital Universitario Infanta Leonor / Universidad Complutense de Madrid, Madrid, Spain, madrid, ¹⁰Hospital Universitario La Paz, MADRID, ¹¹Hospital Universitario La Paz, Rheumatology, Madrid, Madrid, Spain, ¹²Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ¹³LIMA, Advanced Medical Informatics Lab, La Paz Research Institute, IdiPAZ, Madrid, Spain, ¹⁴¹Biomedical Engineering and Telemedicine Centre, ETSIT, Center for Biomedical Technology, Universidad Politéctica de Madrid, TELEMEDICINE, MADRID, Spain,, MADRID
Background/Purpose: Rheumatoid arthritis (RA) and spondyloarthritis (SpA) are immune-mediated inflammatory diseases (IMIDs) characterized by joint and spinal inflammation, leading to functional impairment. Their management requires…
Abstract Number: 2687 • ACR Convergence 2025
Glucagon-like peptide-1 receptor agonists therapy is associated in improvement in psoriatic arthritis-related and metabolic outcomes: A retrospective analysis of two cohorts
Lihi Eder¹, Uma Scher², Kyra Chen³, Alexandra L. Rice³, Sydney Thib⁴ and Rebecca Haberman⁵, ¹University of Toronto, Toronto, ON, Canada, ²NYU School of Medicine, Scarsdale, NY, ³NYU Grossman School of Medicine and NYU Langone Health Psoriatic Arthritis Center, New York, ⁴Women's College Research Institute, Women's College Hospital, Toronto, Canada, ⁵NYU Langone Health, New York, NY
Background/Purpose: Obesity is highly prevalent in psoriatic arthritis (PsA) and is associated with reduced therapeutic response, worse disease outcomes, and increased cardiometabolic risk. Glucagon-like peptide-1…
Abstract Number: 2405 • ACR Convergence 2025
Machine Learning in SLE Diagnosis: Performance of the SLE Risk Probability Index Questionnaire in a Multicenter Cohort of Patients with Systemic Lupus Erythematosus
Joan Manuel Dapeña¹, Eliana Serrano¹, Juan Manuel Bande², María Alejandra Medina², Diana klajn², José Caracciolo², Cecilia Castro³, Julieta Morbiducci⁴, Aixa Lucia Merce⁵, Rossella Tralice⁶, Gabriela Vanesa Espasa⁷, Yessika Jackeline Soria⁷, Maria Lilia Leguizamón⁸, Mariana Pera⁷, Inés Verónica Bellomio⁹, María Silvia Yacuzzi¹⁰, Maximiliano Machado Escobar¹¹, Máximo Cosentino¹², Lucila Garcia¹³, Mercedes Garcia¹², Carolina Aeschlimann¹⁴, Graciela Noemi Gomez¹⁵, Nicolas Perez¹⁶ and Silvia Beatriz Papasidero², ¹Sanatorio Dr Julio Méndez, CABA, Ciudad Autonoma de Buenos Aires, Argentina, ²Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, ³Hospital Z.G.A Dr. Isidoro Iriarte de Quilmes, Quilmes, Buenos Aires, Argentina, ⁴Hospital General de Agudos Bernardino Rivadavia, Capital Federal, Ciudad Autonoma de Buenos Aires, Argentina, ⁵Hospital General de Agudos Bernardino Rivadavia, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁶Hospital General de Agudos Bernardino Rivadavia, Buenos Aires, Argentina, ⁷Hospital Padilla de Tucumán, Tucumán, Argentina, ⁸Hospital Padilla de Tucumán, San Miguel de Tucuman, Argentina, ⁹Hospital Padilla, Tucumán, Argentina, San Miguel de Tucumán, Argentina, ¹⁰Hospital Eva Perón de Tucumán, Tucuman, Argentina, ¹¹Hospital Eva Perón de Tucumán, Tucumán, Argentina, ¹²Hospital Interzonal General de Agudos “General San Martín” de la plata, La Plata, Argentina, ¹³Hospital San Martin de La Plata, La Plata, Argentina, La Plata, Argentina, ¹⁴Hospital Provincial de Rosario, Rosario, Argentina, ¹⁵Instituto de Investigaciones Médicas Dr. Alfredo Lanari, Don Torcuato, Argentina, ¹⁶Instituto de Investigaciones Médicas Dr. Alfredo Lanari, Buenos Aires, Argentina
Background/Purpose: The SLE Risk Probability Index (SLERPI), a clinical prediction model for systemic lupus erythematosus (SLE), was developed using machine‑learning variable‑selection techniques (Random Forest, LASSO).…
Abstract Number: 2092 • ACR Convergence 2025
Associations Among Biomarkers, Cytokines, and Ultrasound Features of Knee Osteoarthritis: A Cross-Sectional Analysis in the Johnston County Health Study
Jasmine Kimber¹, Carolina Alvarez², Virginia Kraus³, Janet Huebner³, Liubov Arbeeva⁴, Todd Schwartz⁵, Yvonne Golightly⁶, Richard Loeser⁷ and Amanda Nelson¹, ¹University of North Carolina at Chapel HIll, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Miami, FL, ³Duke University, Durham, NC, ⁴University of North Carolina, Chapel Hill, Carrboro, NC, ⁵University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁶University of Nebraska Medical Center, Omaha, NE, ⁷University of North Carolina, Chapel Hill, NC
Background/Purpose: Osteoarthritis (OA) is a leading cause of disability worldwide, characterized by progressive joint degeneration, chronic pain and functional impairment (PMID: 24024017). While imaging modalities…
Abstract Number: 1924 • ACR Convergence 2025
Real-World Treatment Patterns of Patients with Systemic Autoimmune Rheumatic Disease-associated Interstitial Lung Disease After Progression in The United States
Joseph Yang¹, Katy Sadowski¹, Akshay Kharat¹, Ann Chauffe¹ and Tejaswini Kulkarni², ¹Boehringer Ingelheim, Ridgefield, CT, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Systemic autoimmune rheumatic diseases (SARDs) are a group of autoimmune diseases that affect multiple organ systems, including the lungs. The development of interstitial lung…
Abstract Number: 1556 • ACR Convergence 2025
Latent Profiles of Parenchymal Abnormalities and Vascular Features Measured by Quantitative CT Identifies a Subgroup of Systemic Sclerosis Patients With a Greater Lung Function Decline Over Time
Alicia Hinze¹, Nishanth Katurkuri², Robert Vassallo², Ami Shah³, Ryan Lennon², Brian Bartholmai² and Cynthia Crowson⁴, ¹Mayo Clinic - Rochester, MN, Rochester, MN, ²Mayo Clinic, Rochester, MN, ³Johns Hopkins Rheumatology, Baltimore, MD, ⁴Mayo Clinic, Stewartvillle, MN
Background/Purpose: The clinical course of interstitial lung disease (ILD) in systemic sclerosis (SSc) is highly variable--some patients experience progressive loss of lung function while others…
Abstract Number: 1416 • ACR Convergence 2025
Structural Damage Progression in the Spine in Patients with Psoriatic Arthritis: Findings from a Longitudinal Cohort Study
Fadi Kharouf¹, Pankti Mehta², Virginia Carrizo Abarza³, Shangyi Gao⁴, Daniel Pereira⁵, Dafna D. Gladman⁶, Vinod Chandran⁷ and Denis Poddubnyy⁸, ¹University Health Network and University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, ²University of Toronto, Gladman Krembil Psoriatic Arthritis Research Program, Toronto, ON, Canada, ³Toronto Western Hospital - University of Toronto, Toronto, ON, Canada, ⁴Gladman-Krembil Psoriatic Arthritis Research Program, Centre for Prognosis Studies in the Rheumatic Diseases, Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada, Toronto, ON, Canada, ⁵University Health Network, Toronto, ON, Canada, ⁶Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, ⁷University of Toronto, Toronto, ON, Canada, ⁸Division of Rheumatology, Department of Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada, and Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany; Department of Epidemiology, German Rheumatism Research Centre, Berlin, Germany
Background/Purpose: Axial involvement is one of the key features of psoriatic arthritis (PsA) and is associated with increased disease burden. However, rates and predictors of…
Abstract Number: 1107 • ACR Convergence 2025
Baseline Data on Rheumatic Immune-related Adverse Events from the Largest Prospective Multicenter US Consortium
Laura Cappelli¹, Namrata Singh², Noha Abdel-Wahab³, Anne R. Bass⁴, Tawnie Braaten⁵, Cassandra Calabrese⁶, Nilasha Ghosh⁷, Tamiko Katsumoto⁸, Sang Kim⁹, Minna Kohler¹⁰, Alexa Meara¹¹, Pankti Reid¹², Jeffrey Sparks¹³, Maria Suarez-Almazor¹⁴, Clifton Bingham¹⁵ and Ami Shah¹⁶, ¹Johns Hopkins School of Medicine, Baltimore, MD, ²University of Washington, Bellevue, WA, ³University of Texas MD Anderson Cancer Center, houston, TX, ⁴Hospital for Special Surgery, New York, NY, ⁵UNIVERSITY OF UTAH, Salt Lake City, UT, ⁶Cleveland Clinic Foundation, Cleveland Heights, OH, ⁷Hospital for Special Surgery, New York, NY, ⁸Division of Immunology and Rheumatology, Stanford University, Millbrae, CA, ⁹Yale University, Branford, CT, ¹⁰Massachusetts General Hospital, Harvard Medical School, Boston, MA, ¹¹The Ohio State University Wexner Medical Center, COLUMBUS, OH, ¹²University of Chicago Medical Center, Chicago, IL, ¹³Brigham and Women's Hospital, Boston, MA, ¹⁴MD Anderson Cancer Center, Houston, TX, ¹⁵Johns Hopkins University, Baltimore, MD, ¹⁶Johns Hopkins Rheumatology, Baltimore, MD
Background/Purpose: Large, multi-center efforts are needed to optimally study rheumatic immune-related adverse events (rh-irAEs) from immune checkpoint inhibitor (ICI) use. We aimed to characterize the…
Abstract Number: 0565 • ACR Convergence 2025
Combination of Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs in Psoriatic Arthritis: A Case-Series
Andre Lucas Ribeiro¹, Virginia Carrizo Abarza², Jensen Yeung³, Khalad Maliyar³, Siddhartha Sood³, Ahmet Bagit³, Muskaan Sachdeva³, Sahil Koppikar⁴, Dafna D. Gladman⁵, Vinod Chandran⁶ and Lihi Eder⁶, ¹Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, ²Toronto Western Hospital - University of Toronto, Toronto, ON, Canada, ³Women's College Hospital & University of Toronto, Toronto, ON, Canada, ⁴Women's College Hospital & University of Toronto, Markham, ON, Canada, ⁵Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, ⁶University of Toronto, Toronto, ON, Canada
Background/Purpose: Despite advances in psoriatic arthritis (PsA) treatment, remission remains elusive for many patients. This has prompted growing interest in combining biologic and targeted synthetic…

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