ACR Meeting Abstracts

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Abstracts tagged "Cohort Study"

  • Abstract Number: 0561 • ACR Convergence 2023

    Frequency of Anti-Ro Antibodies in Systemic Lupus Erythematosus Patients: Insights from Multicenter and National Registry

    Lucia Margarita Mendoza Martinez1, Joan Manuel Dapeña1, Juan Manuel Bande1, Maria Alejandra Medina1, Silvia Papasidero1, José caracciolo1, Rosana Quintana2, Lucila Garcia2, Carla Andrea Gobbi2, Sandy Sapag Durán2, Alberto Spindler2, Analia Patricia Alvarez2, Cecilia Pisoni2, Catalina Gomez2, Raúl Hector Paniego2, María Julia Santa cruz2, Luciana Gonzalez Lucero2, Rodrigo Aguila Maldonado2, Sergio Gordon2, Julia Romero2, Gretel Rausch2, Alberto Allievi2, Alberto Omar Orden2, johana zacariaz hereter3, Roberto Baéz2, Andrea Vanesa González2, Juan Manuel Vandale2, Mario Alberto Goñi2, Victor Caputo4, María Silvia Larroudé2, Graciela Gómez2, Josefina Marin2, Victoria Collado2, Gazzoni María Victoria2, Marcos David Zelaya2, Mónica Sacnún2, Romina Rojas Tessel2, Maira Alejandra Arias Saavedra2, Maximiliano Machado Escobar2, Pablo Astesana2, Ursula Vanesa Paris2, Bernando A. Pons-Estel2 and Mercedes García5, 1Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 2Study Group of the Argentine Society of Rheumatology for Systemic Lupus Erythematosus, Buenos Aires, Argentina, 3Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4Hospital Militar Central, Buenos Aires, Argentina, 5Hospital Interzonal General de Agudos José de San Martín, La Plata, Argentina

    Background/Purpose: Anti-Ro antibodies can be detected in 40% of patients with systemic lupus erythematosus (SLE) and have been associated with various clinical manifestations of the…
  • Abstract Number: 1075 • ACR Convergence 2023

    Impact of Immunosuppression on the Safety and Efficacy of Immune Checkpoint Inhibitors in Patients with Rheumatic Autoimmune Disease: Experience from the Canadian Research Group of Rheumatology in Immuno-Oncology (CanRIO)

    Lourdes Gonzalez Arreola1, Carrie Ye2, Marie Hudson3, Janet Roberts4, Janet Pope5, Thomas Appleton5, Sabrina Hoa6, Aurore Fifi-Mah7, Nancy Maltez8, Alexandra Saltman9, Megan Himmel9, Ines Colmegna10, Alexandra Ladouceur11, Anthony Obrzut1, Jeremiah Tan12, David Moon2, Tatiana Nevskaya5, Emma Schmidt13, Lindsay Cho4, Nader Toban14 and Shahin Jamal15, 1Arthritis Research Canada, Vancouver, BC, Canada, 2University of Alberta, Edmonton, AB, Canada, 3McGill University, Montréal, QC, Canada, 4Dalhousie University, Halifax, NS, Canada, 5University of Western Ontario, London, ON, Canada, 6University of Montreal, Brossard, QC, Canada, 7University of Calgary, Calgary, AB, Canada, 8The Ottawa Hospital, Ottawa, ON, Canada, 9University of Toronto, Toronto, ON, Canada, 10The Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 11Department of Rheumatology of McGill University and CHU-Bordeaux, Montréal, QC, Canada, 12Arthritis Research Canada, Vancouver, Canada, Vancouver, BC, Canada, 13University of British Columbia, Vancouver, BC, Canada, 14Centre Hospitalier de l'Université de Montréal, Dollard-des-Ormeaux, QC, Canada, 15Vancouver Coastal Health, Vancouver, BC, Canada

    Background/Purpose: Immune checkpoint inhibitors (ICI) have changed the landscape of treatment for many cancers. However, most cancer clinical trials for ICI excluded patients with pre-existing…
  • Abstract Number: 1632 • ACR Convergence 2023

    Incident Malignancies in Patients with Rheumatoid Arthritis in Daily Rheumatological Care

    Martin Schaefer1, Yvette Meissner1, Bernhard Manger2, Sylvia Berger3, Karin Rockwitz4, Anne Regierer5 and Anja Strangfeld1, 1German Rheumatism Research Center, Berlin, Germany, 2Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, 3Rheumatologist, Naunhof, Germany, 4Rheumatologist, Goslar, Germany, 5Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany

    Background/Purpose: In 2021, the European and US-American regulatory agencies EMA and FDA issued warnings about malignancy risk associated with the Janus kinase inhibitor (JAKi) tofacitinib…
  • Abstract Number: 2308 • ACR Convergence 2023

    The Association Between Poverty and SLE Disease Burden: Experiences from a Saint Lucian Cohort

    Amanda King1, Catherine Brown2, Cleopatra Altenor1, Timothy Niewold3 and Ashira Blazer3, 1Bay Medical Centre, Castries, Saint Lucia, 2The University of the West Indies, Bridgetown, Barbados, 3Hospital for Special Surgery, New York, NY

    Background/Purpose: Poverty increases non-communicable disease risk, however its influence on systemic lupus erythematosus (SLE) burden is poorly understood. Non-White racial/ethnic groups, particularly of African origin,…
  • Abstract Number: 0209 • ACR Convergence 2023

    Safety of Bivalent SARS-CoV-2 Vaccines as a Second Booster Dose in Arthritis Patients on Immunosuppressive Therapies

    Hilde Ørbo1, Ingrid Jyssum1, Anne Therese Tveter1, Ingrid Christensen1, Joseph Sexton1, Kristin Hammersbøen Bjørlykke2, Grete B. Kro3, Tore Kvien1, Gunnveig Grødeland4, Ludvig A. Munthe5, Siri Mjaaland6, John Torgils Vaage5, Espen Haavardsholm1, Kristin Kaasen Jørgensen2, Sella Provan7, Silje Watterdal Syversen1 and Guro Goll1, 1Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 2Department of Gastroenterology, Akershus University Hospital, Oslo, Norway, 3Department of Microbiology, Oslo University Hospital, Oslo, Norway, 4Department of Immunology, Oslo University Hospital, Oslo, Norway, 5Department of Immunology, Oslo University Hospital, Oslo, Norway, 6Norwegian Institute of Public Health, Oslo, Norway, 7Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: Safety and efficacy of updated bivalent vaccines, containing both the original vaccine variant of SARS-CoV-2 Spike and either Omicron variants BA.1 or BA.4/5, are…
  • Abstract Number: 0576 • ACR Convergence 2023

    Enhancing Systemic Lupus Erythematosus Diagnosis: Comparative Performance Characteristics of TC4d and Anti-T-Cell Antibodies with Conventional Biomarkers

    Andrew Concoff1, Vasileios Kyttaris2, Vaneet Sandhu3, Tyler O'Malley4, Giorgio Casaburi4, Sudha Kumar4, Chau Ching Liu5, Susan Manzi6 and Joeseph Ahearn5, 1Exagen, Los Angeles, CA, 2BIDMC, Boston, MA, 3Loma Linda University, Loma Linda, CA, 4Exagen, Vista, CA, 5Allegheny Health Network, Pittsburgh, PA, 6Lupus Center of Excellence, Autoimmunity Institute, Allegheny Health Network, Pittsburgh, PA

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic, systemic autoimmune disease, affecting multiple organ systems with varying severity among patients. SLE presents a diagnostic challenge…
  • Abstract Number: 1109 • ACR Convergence 2023

    Genetic Risk Variants in Hyperuricemia and Gout: Common Disease, Multiple Common and Rare Variant Hypothesis

    Blanka Stiburkova1, Katerina Pavelcova2, Jana Masinova1, Marketa Pavlikova3 and Karel Pavelka4, 1Institute of Rheumatology, Prague, Czech Republic, 2Institute of Rheumatology, Praha 2, Czech Republic, 3Department of Probability and Mathematical Statistics, Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic, 4Institut of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Praha, Czech Republic

    Background/Purpose: Hyperuricemia is a central feature in the pathogenesis of gout. Hyperuricemia results from an imbalance between endogenous production and excretion of urate; however, the…
  • Abstract Number: 1642 • ACR Convergence 2023

    Identifying Distinct Phenotypes in Psoriatic Arthritis: A Study from the Psoriatic Arthritis Research Consortium (PARC) Cohort

    Paras Karmacharya1, Daniel W. Byrne2, Alisa Stephens-Shields3, Leslie Crofford4, M. Elaine Husni5, Jose Scher6, Ethan Craig3, Robert Fitzsimmons3, Soumya Reddy7, Marina Nighat Magrey8, Jessica A Walsh9 and Alexis R Ogdie3, 1Vanderbilt University, Nashville, TN, 2Vanderbilt University Medical Center, Nashville, TN, 3University of Pennsylvania, Philadelphia, PA, 4Vanderbilt University Medical Center, Melbourne, AR, 5Cleveland Clinic / Department of Rheumatic and Immunologic Diseases, Cleveland, OH, 6New York University School of Medicine, New York, NY, 7NYU School of Medicine, New York, NY, 8Case Western Reserve University, University Hospitals, Cleveland, OH, 9Salt Lake City Veterans Affairs Health and University of Utah Health, Division of Rheumatology, Salt Lake City, UT

    Background/Purpose: Despite an increasing number of therapeutic options, less than one-third of patients with PsA achieve remission. A major cause of non-response is that PsA…
  • Abstract Number: 2351 • ACR Convergence 2023

    Health Outcomes Among Patients (Pts) with SLE Initiating Belimumab (BEL) with and Without the Use of Immunosuppressants in the Previous 2 Years

    Yan Chen1, Karen Worley2, Brendan Rabideau1, Bernard Rubin3, Benson Wu1, Rose Chang1 and Maral DerSarkissian1, 1Analysis Group, Boston, MA, 2GlaxoSmithKline, US Value Evidence and Outcomes, Cincinnati, OH, 3GlaxoSmithKline, US Medical Affairs and Immuno-inflammation, Durham, NC

    Background/Purpose: BEL efficacy in pts with SLE has been previously demonstrated in clinical and real-world studies.1 However, there are limited data on differences in outcomes…
  • Abstract Number: 0273 • ACR Convergence 2023

    Disease Characteristics and Pancreatic Damage in IgG4-Related Disease with Pancreatic Involvement

    Guy Katz1, Liam Harvey2, Yasmin Hernandez-Barco1, Ana Fernandes1, Grace McMahon1, Isha Jha1, Zachary Wallace3, Cory Perugino1 and John Stone4, 1Massachusetts General Hospital, Boston, MA, 2Frank H. Netter School of Medicine at Quinnipiac University, New Haven, CT, 3Massachusetts General Hospital, Newton, MA, 4Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Concord, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic immune-mediated fibroinflammatory disease that can affect nearly every organ system. Autoimmune pancreatitis (AIP) is among the most common…
  • Abstract Number: 0634 • ACR Convergence 2023

    Prevalence and Associations of Anaemia in Systemic Sclerosis Patients in a National Observational Cohort; Results from the Australian Scleroderma Cohort Study

    Raychel Barallon1, Gene-Siew Ngian1, Diane Apostolopoulos1, Dylan Hansen2, Kathleen Morrisroe3, Wendy Stevens4, Susanna Proudman5, Mandana Nikpour6 and Joanne Sahhar1, 1Monash Health and Monash University, Clayton, Australia, 2Department of Rheumatology, St Vincent’s Hospital Melbourne, Fitzroy, Australia, 3The University of Melbourne at St Vincent’s Hospital Melbourne, Fitzroy, Australia, 4Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, Australia, 5Royal Adelaide Hospital and University of Adelaide, Adelaide, Australia, 6The University of Melbourne at St. Vincent’s Hospital Melbourne, Departments of Medicine and Rheumatology, Melbourne, Australia

    Background/Purpose: Anaemia in systemic sclerosis (SSc) is under-studied and under-characterised. Its prevalence amongst SSc patients is not well described, nor are its effects on outcomes…
  • Abstract Number: 1119 • ACR Convergence 2023

    Preliminary Descriptive Analysis of the RADIAL Cohort Study About the Prevalence and the Clinical Characteristics of Patients with CPPD in Daily Clinical Practice

    Silvia Sirotti1, Joao Madruga-Dias2, Antonella Adinolfi3, Garifallia Sakellariou4, Davide Rozza5, Greta Carrara5, Gianpiero Landolfi5, Carlo Alberto Scire5, Annamaria Iagnocco6 and Georgios Filippou1, 1IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, 2Centro Hospitalar do Médio Tejo, NOVA Medical School, Lisbon, Portugal, 3Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milano, Italy, 4Department of Internal Medicine and Therapeutics, Università di Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy, 5Società Italiana di Reumatologia, Epidemiology Research Unit, Milan, Italy, 6University of Turin, Roma, Italy

    Background/Purpose: The RADIAL study is aimed to evaluate the performance of a composite approach, based on clinical, laboratory and ultrasound (US) data in the differential…
  • Abstract Number: 1675 • ACR Convergence 2023

    Survival in Patients with Rheumatoid Arthritis and Early Breast Cancer Treated with Tumor Necrosis Factor Inhibitors

    Maria Suarez-Almazor1, Juan Ruiz2, Xiudong Lei2, Chi-Fang Wu2, Hui Zhao2, Suja Rajan3, Heather Lin2 and Sharon Giordano2, 1MD Anderson Cancer Center, Houston, TX, 2The University of Texas, MD Anderson Cancer Center, Houston, TX, 3University of Texas School of Public Health, Houston, TX

    Background/Purpose: There have been concerns about the use of tumor necrosis factor inhibitors (TNFi) in patients with rheumatoid arthritis (RA) and concomitant cancer. Few studies…
  • Abstract Number: 2377 • ACR Convergence 2023

    The Impact of Chronologic versus Biologic Age on the Risk of Severe Infection, End-Stage Renal Disease, and Death in Older Adults with ANCA-Associated Vasculitis

    Sebastian Sattui1, Xiaoqing Fu2, Claire Cook2, Shruthi Srivatsan2, Yuqing Zhang2 and Zachary Wallace3, 1University of Pittsburgh, Pittsburgh, PA, 2Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital, Newton, MA

    Background/Purpose: Older adults with ANCA-associated vasculitis (AAV) have distinct clinical presentations and outcomes when compared to younger adults. Despite a high incidence of AAV in…
  • Abstract Number: 0330 • ACR Convergence 2023

    Patient-Reported Experiences and Comorbidities in Patients with IgG4-Related Disease with and Without Pancreatic Involvement

    Liam Harvey1, Guy Katz2, Yasmin Hernandez-Barco2, Ana Fernandes2, Aubree McMahon2, Grace McMahon2, Isha Jha2, Zachary Wallace3, Cory Perugino2 and John Stone4, 1Frank H. Netter School of Medicine at Quinnipiac University, New Haven, CT, 2Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital, Newton, MA, 4Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Concord, MA

    Background/Purpose: IgG4-Related Disease (IgG4-RD) is a systemic immune-mediated disease that commonly involves the pancreas in the form of autoimmune pancreatitis (AIP). Despite being one of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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