Abstracts tagged "Cardiovascular"

Abstract Number: 1795 • ACR Convergence 2020
Intracellular Homocysteine and Homocysteine Metabolites in Systemic Lupus Erythematosus (SLE)
George Stojan¹, Jessica Li¹, Amrita Raj², Maureen Kane³ and Michelle Petri⁴, ¹Johns Hopkins University, BALTIMORE, MD, ²Johns Hopkins University, Baltimore, ³University of Maryland School of Pharmacy, Baltimore, ⁴Johns Hopkins University School of Medicine, Baltimore
Background/Purpose: In SLE, homocysteine has been shown to be a potentially modifiable, independent risk factor for stroke and thrombotic events. All previous epidemiological studies used…
Abstract Number: 0650 • ACR Convergence 2020
Risk of Vertebral Fractures at Lateral Chest Radiographies in Patients with Gout
Marco Ferrández-Jiménez¹, Irene Calabuig², Maria Luisa Peral², Miguel Gómez-Garberí¹ and Mariano Andrés², ¹Universidad Miguel Hernández de Elche, Alicante, Spain, ²Hospital General Universitario de Alicante-ISABIAL and Universidad Miguel Hernández de Elche, Alicante, Spain
Background/Purpose: Osteoporosis causes significant morbidity and mortality through the development of fragility fractures, including vertebral fractures (VF). Patients with gout may show an increased risk…
Abstract Number: 1185 • ACR Convergence 2020
Performance of the MBDA-based CVD Risk Score in RA Patient Groups of Clinical Interest
Jeffrey R Curtis¹, Fenglong Xie², Cynthia Crowson³, Eric Sasso⁴, Elena Hitraya⁴, Cheryl Chin⁵, Richard Bamford⁵, Rotem Ben-Shachar⁵, Alexander Gutin⁵, Darl Flake⁵, Brent Mabey⁵ and Jerry Lanchbury⁵, ¹Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Mayo Clinic, Rochester, Minnesota, USA, Rochester, MN, ⁴Myriad Autoimmune, South San Francisco, CA, ⁵Myriad Genetics, Inc., Salt Lake City, UT
Background/Purpose: A novel risk prediction score combines serum biomarkers from the multi-biomarker disease activity (MBDA) test with clinical information to predict 3-year risk for a…
Abstract Number: 1393 • ACR Convergence 2020
Systemic Sclerosis: Subclinical Aterosclerosis and Morbimortality
Miriam Retuerto¹, Jose Luis Rosales², Maria Martin¹, Beatriz Joven¹ and Patricia E Carreira¹, ¹Hospital universitario 12 de octubre, Madrid, Spain, ²Hospiten Rambla, Santa Cruz de Tenerife, Spain
Background/Purpose: Rheumatic diseases are associated with accelerated atherosclerosis, and an increase in cardiovascular morbidity and mortality. This process is mediated by classic cardiovascular risk factors…
Abstract Number: 1821 • ACR Convergence 2020
Early Assessment of Left Ventricular Assessment Using Speckle Tracking Echocardiography and It´s Relationship with Insulin Resistance in Women with Systemic Lupus Erythematosus
Pamela Munguía-Realpozo¹, Claudia Mendoza-Pinto², Socorro Méndez-Martínez², Liliana Pérez-Aquino³, Ivet Etchegaray-Morales¹ and Mario Garcia-Carrasco², ¹Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, Puebla, Puebla, Mexico, ²Instituto Mexicano del Seguro Social, Puebla, Puebla, Mexico, ³Facultad de Medicina, Beneméria Universidad Autónoma de Puebla, Puebla, Puebla, Mexico
Background/Purpose: Systemic lupus erythematosus patients (SLE) have increased cardiovascular risk. Patients with SLE are associated with significant alterations in cardiac structure and function as demonstrated…
Abstract Number: 0654 • ACR Convergence 2020
The Effects of Dietary Macronutrients on Serum Urate: A Secondary Analysis of the OmniHeart Trial
Matthew Belanger¹, Christina Wee¹, Kenneth Mukamal¹, Edgar Miller², Frank Sacks³, Lawrence Appel², Robert Shmerling⁴, Hyon Choi⁵ and Stephen Juraschek¹, ¹Beth Israel Deaconess Medical Center/Harvard Medical School, Division of General Medicine, Boston, MA, ²Johns Hopkins University, School of Medicine, Department of Medicine, Division of General Internal Medicine, Baltimore, MD, ³Harvard T. H. Chan School of Public Health, Department of Nutrition, Boston, MA, ⁴Beth Israel Deaconess Medical Center/Harvard Medical School, Division of Rheumatology, Mashpee, MA, ⁵Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA
Background/Purpose: Diet is a significant determinant of hyperuricemia and risk for gout. Dietary recommendations to prevent gout emphasize reducing purine intake; however, low-purine diets are…
Abstract Number: 1187 • ACR Convergence 2020
Red Cell Distribution Width Is Associated with ASCVD Risk Score and CVD in RA After Initiation of Methotrexate
Ibtissam Gad¹, Sofi Damjanovska², Lenche Kostadinova³, Alyssa Lange⁴, Christopher Burant⁴, Brigid Wilson⁵, Taissa Bej⁵, Nora Singer⁶, Maya Mattar⁷, David Zidar⁸ and Donald Anthony⁹, ¹Case Western Reserve/ Cleveland VA Medical Center, Cleveland Heights, OH, ²Case Western Reserve University/Cleveland VA Medical Center, Cleveland Heights, OH, ³(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Highland Heights, OH, ⁴Case Western Reserve University, Cleveland, ⁵Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, ⁶The MetroHealth System, Case Western Reserve University School of Medicine, Cleveland, OH, ⁷Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, ⁸Case Western Reserve University/Cleveland VA Medical Center, Cleveland, ⁹Case Western Reserve University/Cleveland VA Medical Center/MetroHealth Medical Center, Cleveland, OH
Background/Purpose: Rheumatoid arthritis (RA) has been shown to be associated with increased risk of cardiovascular disease (CVD) and mortality. Red cell distribution width (RDW) represents…
Abstract Number: 1425 • ACR Convergence 2020
Reduced Risk of Cardiovascular Diseases Events with Renal Transplantation in Granulomatosis with Polyangiitis in the United States: Data from the US Renal Data System
Zachary Wallace¹, April Jorge², Xiaoqing Fu³, Yuqing Zhang⁴ and Hyon Choi⁵, ¹Massachusetts General Hospital, Newton, MA, ²Massachusetts General Hospital, Boston, MA, ³Massachusetts General Hospital, Boston, ⁴Massachusetts General Hospital, Quincy, MA, ⁵Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA
Background/Purpose: Granulomatosis with polyangiitis (GPA) is a common cause of glomerulonephritis and leads to end-stage renal disease (ESRD) in approximately 25% of patients. Both GPA…
Abstract Number: 1856 • ACR Convergence 2020
Abnormal DNA Methylation in CD4+T Cells Is Associated with Cardiovascular Risk in Psoriatic Arthritis
Iván Arias de la Rosa¹, Maria Dolores Lopez-Montilla², Carlos Pérez-Sánchez¹, Javier Rodriguez-Ubreva³, Esteban Ballestar³, Carmen Torres-Granados¹, María-Carmen Abalos-Aguilera¹, Ignacio Gómez-García¹, Alejandra Maria Patiño-Trives¹, Maria Luque-Tevar¹, Eduardo Collantes-Estévez⁴, Chary Lopez-Pedrera⁵, Alejandro Escudero-Contreras⁴, Clementina Lopez-Medina⁶ and Nuria Barbarroja¹, ¹Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, ²IMIBIC/University of Cordoba/Reina Sofia Hospital, Cordoba, Spain, ³Josep Carreras Institute (IJC), Badalona, Spain, ⁴Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, ⁵IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ⁶Rheumatology Department, Cochin Hospital, Paris, Paris, France
Background/Purpose: Cardiovascular risk factors are increased in Psoriatic Arthritis (PsA). Latest studies suggested that inflammatory and metabolic disorders may be under epigenetic control, including DNA…
Abstract Number: 0671 • ACR Convergence 2020
Structured Cardiovascular Assessment in Gout Incorporating Carotid Ultrasound: Analysis of Subsequent Events in the Follow-Up
Mar Monzó¹, Neus Quilis², Laura Ranieri², Alejandro San-Martín³ and Mariano Andrés⁴, ¹Universidad Miguel Hernández, Alicante, Spain, ²Hospital Universitario del Vinalopó, Alicante, Spain, ³Clínica HLA Vistahermosa, Alicante, Spain, ⁴Hospital General Universitario de Alicante-ISABIAL and Universidad Miguel Hernández de Elche, Alicante, Spain
Background/Purpose: Gout is an independent cardiovascular (CV) risk factor. This excess of morbidity and mortality requires optimal management, especially in high-risk individuals. Therefore, the inclusion…
Abstract Number: 1188 • ACR Convergence 2020
Serum Anti-malondialdehyde-acetaldehyde IgA Antibody Concentration Improves Prediction of Coronary Atherosclerosis Beyond Traditional Risk Factors in Patients with Rheumatoid Arthritis
Hannah Lomzenski¹, Geoffrey Thiele², Michael Duryee², Sheau-Chiann Chen¹, Fei Ye¹, Ted Mikuls², C. Michael Stein¹ and Michelle Ormseth¹, ¹Vanderbilt University Medical Center, Nashville, TN, ²University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Patients with rheumatoid arthritis (RA) have increased cardiovascular disease (CVD) independent of traditional risk factors. Oxidative stress is increased in patients with RA and…
Abstract Number: 1447 • ACR Convergence 2020
Vitamin D Deficiency Enhances Antiphospholipid Antibody-Mediated Thrombosis in a Passive Immunization Mouse Model
Rohan Willis¹, Karen Roye-Green², Zurina Romay-Penabad¹, Elizabeth Papalardo¹, Alvaro Schleh³, Vijaya Murthy⁴, Monica Smikle² and Emilio Gonzalez¹, ¹University of Texas Medical Branch, Galveston, TX, ²University of the West Indies, Kingston, Jamaica, ³Antiphospholipid Standardization Laboratory, GALVESTON, TX, ⁴University of Texas Medical Branch, League City, TX
Background/Purpose: Abnormal vitamin D levels occur frequently in antiphospholipid (APS) patients and are correlated with thrombosis. It remains unclear however if vitamin D deficiency observed…
Abstract Number: 1883 • ACR Convergence 2020
Exercise Partially Explains the Impact of Body Mass Index on Disease Activity in Ankylosing Spondylitis
Jean Liew¹, Milena Gianfrancesco², Susan Heckbert¹ and Lianne Gensler³, ¹University of Washington, Seattle, WA, ²University of California, San Francisco, San Francisco, CA, ³University of California San Francisco, San Francisco, CA
Background/Purpose: Ankylosing spondylitis (AS) patients have elevated cardiovascular (CV) morbidity and mortality compared to general population comparators of the same age and sex. Although obesity…

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