ACR Meeting Abstracts

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Abstracts tagged "calcinosis"

  • Abstract Number: 1641 • 2019 ACR/ARP Annual Meeting

    Change in Calcinosis over 1 Year Using the SCTC Radiologic Scoring System for Calcinosis of the Hands in Patients with Systemic Sclerosis

    Antonia Valenzuela1, Melody Chung 2, Tatiana S. Rodríguez-Reyna 3, Susanna Proudman 4, Murray Baron 5, Flavia Castelino 6, Vivien Hsu 7, Shufeng Li 8, David Fiorentino 9, Kathryn Stevens 10 and Lorinda Chung 2, 1Pontificia Universidad Catolica de Chile, Santiago de Chile, Chile, 2Stanford University, Palo Alto, CA, 3Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 4Royal Adelaide Hospital North Terrace, Adelaide, Australia, 5Jewish General Hospital, McGill University, Montreal, Canada, 6Harvard University, Boston, MA, 7Rutgers- RWJ Medical School, SOUTH PLAINFIELD, NJ, 8Division of Immunology and Rheumatology, Department of Medicine, Stanford, Palo Alto, CA, 9Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, 10Stanford University, Stanford

    Background/Purpose: Calcinosis cutis is a debilitating complication of systemic sclerosis (SSc) affecting one quarter of patients, most frequently involving the hands. We previously developed and…
  • Abstract Number: 2590 • 2019 ACR/ARP Annual Meeting

    Computer Vision Applied to Dual Energy Computed Tomography Images for Precise Calcinosis Cutis Quantification in Patients with Systemic Sclerosis

    Anita Chandrasekaran1, Imran Omar 2, Zhicheng Fu 3, Shangping Ren 3 and Monique Hinchcliff 1, 1Yale University, Section of Rheumatology, Allergy and Immunology, New Haven, CT, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3San Diego State University, Department of Computer Science, San Diego, CA

    Background/Purpose: Calcinosis cutis, found in both systemic sclerosis (SSc) and juvenile dermatomyositis patients, can be extensive and debilitating. Potential treatments have been identified, but a…
  • Abstract Number: 2607 • 2019 ACR/ARP Annual Meeting

    Ultrasound Detection of Calcinosis and Correlation with Ulnar Artery Occlusion in Patients with Systemic Sclerosis

    Robert Fairchild1, Melody Chung 1, Laurel Sharpless 1, Shufeng Li 2 and Lorinda Chung 1, 1Stanford University, Palo Alto, CA, 2Division of Immunology and Rheumatology, Department of Medicine, Stanford, Palo Alto, CA

    Background/Purpose: Systemic Sclerosis (SSc) is a progressive fibrotic and vascular disease affecting multiple organs. Calcinosis cutis in SSc is characterized by calcium deposition in the…
  • Abstract Number: 2612 • 2019 ACR/ARP Annual Meeting

    Minocycline for Refractory Calcinosis in Systemic Sclerosis: A Single-Centre Observational Cohort Study

    Carmen Fonseca1, Voon Ong 2 and Christopher Denton 3, 1UCL Medical School, Royal Free Campus, London, United Kingdom, 2UCL Medical School, Royal Free Campus, London, 3University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, UK, London, United Kingdom

    Background/Purpose: Calcinosis represents a major challenge for patients with systemic sclerosis (SSc) for which there is no standard therapy. Minocycline has been proposed for treatment…
  • Abstract Number: 479 • 2018 ACR/ARHP Annual Meeting

    Intravenous Immunoglobulin in Combination with Intravenous Methylprednisolone in the Treatment of Calcinosis Associated with Juvenile Dermatomyositis (JDM)

    Marc Phillpotts1, Eman Alshaikh1, Yaseen Aleatany1, Olcay Y. Jones2, Gulnara Mamyrova1, Lisa G. Rider3 and Rodolfo Curiel1, 1Department of Medicine, Division of Rheumatology, The George Washington University, Washington, DC, 2Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, 3Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD

    Background/Purpose: Calcinosis is a major complication of JDM and is associated with disability and poor quality of life. There are no known effective treatments for…
  • Abstract Number: 482 • 2018 ACR/ARHP Annual Meeting

    The Association of Short-Term Ultraviolet Radiation Exposure and Calcinosis in Juvenile Dermatomyositis in the Childhood Arthritis & Rheumatology Research Alliance Registry

    Jessica Neely1, Craig S. Long2, Hugh Sturrock3 and Susan Kim4, 1Pediatric Rheumatology, University of California, San Francisco, San Francisco, CA, 2National Oceanic and Atmospheric Administration (NOAA)/Climate Prediction Center, College Park, MD, 3Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 4Pediatric Rheumatology, University of California, San francisco School of Medicine, San Francisco, CA

    Background/Purpose: JDM is an autoimmune systemic vasculopathy characterized by myositis and skin rash.  Some myositis specific antibodies (MSAs) are associated with clinical manifestations in JDM,…
  • Abstract Number: 1724 • 2018 ACR/ARHP Annual Meeting

    Effectiveness and Safety of Rituximab for the Treatment of Refractory Systemic Sclerosis Associated Calcinosis: A Case Series

    Francisco Javier Narváez1, Juan Pablo Pirola2, Judit Lluch3, Pablo Juárez3, Isabel Morales3 and Joan Miquel Nolla3, 1Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, 2Rheumatology, Hospital Privado Centro Médico de Córdoba, Cordoba, Argentina, 3Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: To analyze the effectiveness and safety of rituximab (RTX) for the treatment of refractory systemic sclerosis (SSc)–associated calcinosis. Methods: We undertook an observational study…
  • Abstract Number: 2026 • 2018 ACR/ARHP Annual Meeting

    Calcium Crystal-Mediated Netosis in Juvenile Dermatomyositis and Anti-RNP+ Overlap Syndrome with Skin Involvement

    Christian Lood1, Gabrielle A. Morgan2, Marisa Klein-Gitelman3, Megan L. Curran4 and Lauren M. Pachman5, 1Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, 2Cure JM Program of Excellence in Myositis Research, Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, 3Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 4Section of Rheumatology, Children's Hospital of Colorado, Denver, CO, 5Cure JM Program of Excellence in Juvenile Myositis Research, Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL

    Background/Purpose: Neutrophils are key immune cells participating in host defense through several mechanisms, including the formation of neutrophil extracellular traps (NETs). Although beneficial from a…
  • Abstract Number: 2981 • 2018 ACR/ARHP Annual Meeting

    Mitochondrial Extrusion and Autoimmunity in Juvenile Dermatomyositis

    Christian Lood1, Bhargavi Duvvuri2, Richard Moore2, Gabrielle A. Morgan3, Marisa Klein-Gitelman4, Megan L. Curran5 and Lauren M. Pachman6, 1Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA, 2Division of Rheumatology, University of Washington, Seattle, WA, 3Cure JM Program of Excellence in Myositis Research, Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, 4Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 5Section of Rheumatology, Children's Hospital of Colorado, Denver, CO, 6Cure JM Program of Excellence in Juvenile Myositis Research, Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL

    Background/Purpose: We recently made the fundamental observation that mitochondrial extrusion is instrumental in mediating inflammation, autoimmunity and organ damage in lupus. Mitochondrial stress and mitochondrial…
  • Abstract Number: 2053 • 2017 ACR/ARHP Annual Meeting

    Computed Tomography Dependent Diagnosis of Crowned Dens Syndrome; A Cervical Manifestation of Patients with Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

    Ammar Haikal1, Brian Everist2, Pim Jetanalin3 and Mehrdad Maz3, 1Department Internal Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, 2Department of Radiology (MSK), Department of Radiology (MSK), University of Kansas Medical Center, Kansas City, KS, 3Allergy, Clinical Immunology, and Rheumatology, Division of Allergy, Clinical Immunology and Rheumatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS

    Background/Purpose:   Crowned Dens Syndrome (CDS), a variation of Calcium Pyrophosphate Deposition Disease (CPPD), is a radiologic-clinical entity defined by the association of radiological calcifications around…
  • Abstract Number: 2137 • 2017 ACR/ARHP Annual Meeting

    Clinical Factors Associated with Long-Term Damage and Calcinosis in an Adult-Age Referral Population of Juvenile Myositis Patients

    Vladislav Tsaltskan1, Annette Aldous2, Sam Serafi1, Heidi Sami1, Gulnara Mamyrova1, Frederick W Miller3, Sam Simmens2, Rodolfo Curiel1, Olcay Y. Jones4 and Lisa G Rider3, 1Department of Rheumatology, George Washington University, Washington, DC, 2Department of Epidemiology and Biostatistics, George Washington University Milken Institute School of Public Health, Washington, DC, 3Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, 4Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD

    Background/Purpose:  Juvenile idiopathic inflammatory myopathies (JIIM) are rare, autoimmune chronic muscle diseases of childhood with significant potential long-term morbidity. In this study we investigate associations…
  • Abstract Number: 1898 • 2016 ACR/ARHP Annual Meeting

    The Lack of Association of Osteoporosis with Proton Pump Inhibitor in Scleroderma: A UK Single Centre Cohort Experience

    Ana Afonso1, Svetlana Nihtyanova2, Christopher Denton3 and Voon H. Ong4, 1Internal Medicine, Hospital Pedro Hispano, EPE, Porto, Portugal, 2Centre for Rheumatology and Connective Tissue Diseases, University College London Medical School, Royal Free Hospital, London, United Kingdom, 3Division of Medicine, Centre for Rheumatology and Connective Tissue Disease, University College London, London, United Kingdom, 4Rheumatology, UCL Division of Medicine, London, United Kingdom

    Background/Purpose: Recent studies suggest that proton pump inhibitor (PPI) use is variably associated with risk of osteoporosis. The aim of this study was to investigate…
  • Abstract Number: 836 • 2016 ACR/ARHP Annual Meeting

    Comprehensive Characterization of Calcinosis in a Multicenter International Cohort of Patients with Systemic Sclerosis

    Antonia Valenzuela1,2, Jessica K. Gordon3, Tatiana Sofia Rodriguez-Reyna4, Susanna Proudman5,6, Murray Baron7, Monique Hinchcliff8, Dinesh Khanna9, Amber Young10, Flavia V. Castelino11, Sara R. Schoenfeld12, Virginia D. Steen13, David Fiorentino14 and Lorinda Chung15, 1Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, 2Stanford University School of Medicine, Stanford, CA, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 5Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia, 6Discipline of Medicine, University of Adelaide, Adelaide, Australia, 7Rheumatology, McGill University, Jewish General Hospital, Montreal, QC, Canada, 8Northwestern University, Feinberg School of Medicine Scleroderma Program, Chicago, IL, 9University of Michigan, Ann Arbor, MI, 10Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, 11Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 12Rheumatology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 13Rheumatology, Georgetown University Medical Center, Washington, DC, 14Department of Dermatology, Stanford University School of Medicine, Palo Alto, CA, 15Rheumatology, Stanford University Medical Center, Palo Alto, CA

    Background/Purpose: Calcinosis cutis is a debilitating complication of systemic sclerosis (SSc) affecting one quarter of patients. Repetitive trauma may be involved in the pathogenesis of…
  • Abstract Number: 841 • 2016 ACR/ARHP Annual Meeting

    Low Nucleoside Triphosphate Pyrophosphohydrolase Activity Contributes to Pathologic Mineralization in Systemic Sclerosis

    Yue Ding1, Supraja Yeturi1, Claudia Gohr1, Mary Ellen Csuka1 and Ann K. Rosenthal2,3, 1Medicine, Medical College of Wisconsin, Milwaukee, WI, 2Division of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, 3Medicine, Clement J. Zablocki VA Medical Center, Milwaukee, WI

    Background/Purpose: Calcinosis is a major source of morbidity in patients with systemic sclerosis (SS). In addition, increased coronary calcification has been reported in patients with…
  • Abstract Number: 2960 • 2015 ACR/ARHP Annual Meeting

    Sodium Thiosulfate in Calcinosis

    Eliza Pelrine1, Jessica K. Gordon2, Murray Baron3 and Robert F. Spiera2, 1Hospital for Special Surgery, New York, NY, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Rheumatology, McGill University, Jewish General Hospital, Montreal, QC, Canada

    Background/Purpose: Calcinosis occurs in ~25% of patients with Systemic Sclerosis (SSc) and causes pain, morbidity, and decreased quality of life. The treatment of calcinosis is…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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