Abstract Number: 2206 • 2019 ACR/ARP Annual Meeting
MRI-based Textural Analysis of Trabecular Bone: A Novel Method for the Opportunistic Screening of Bone Quality
Background/Purpose: A major obstacle to the treatment of osteoporosis and prevention of fractures is that many at-risk patients are never screened. Dual energy x-ray absorptiometry…Abstract Number: 339 • 2018 ACR/ARHP Annual Meeting
Documenting Bone Health for Veterans with Rheumatoid Arthritis in an Outpatient Academic Clinic
Background/Purpose: Rheumatoid arthritis (RA) increases the risk of bone density abnormalities such as osteoporosis, predisposing patients to fragility fractures and subsequent morbidity. Osteoporotic fractures incur…Abstract Number: 2812 • 2018 ACR/ARHP Annual Meeting
Evaluation of Cortical Microarchitecture, Bone Stiffness and Bone Remodeling in Patients with Atypical Femoral Fracture
Background/Purpose: Atypical femoral fractures (AFF) are low energy femoral fractures and subtrochanteric/diaphyseal localization that have been related to long-term bisphosphonate therapy. Patients with AFF exhibit…Abstract Number: 2854 • 2018 ACR/ARHP Annual Meeting
Majeed Syndrome Causing LPIN2 mutations May Prevent Bone “Healing” By Rendering M2 Macrophage Proinflammatory
Background/Purpose: To study the mechanism that leads to bone inflammation in a 4-year old patient of mixed Puerto Rican and African-American background who presented with…Abstract Number: 400 • 2017 ACR/ARHP Annual Meeting
Combination of the Collagen-Induced Arthritis and Organic Dust-Induced Airway Inflammation Models As a Model of Interstitial Lung Disease in Rheumatoid Arthritis
Background/Purpose: Rheumatoid Arthritis (RA) is characterized by extra-articular involvement including interstitial/inflammatory lung disease (ILD). Whereas the coexistence of RA and ILD is known, mechanisms…Abstract Number: 1891 • 2017 ACR/ARHP Annual Meeting
Low Alkaline Phosphatase Levels: Could It be Hypophosphatasia?
Background/Purpose: Hypophosphatasia (HPP) is a rare inherited disorder caused by mutations in ALPL (alkaline phosphatase liver type ALPL gene). Clinical presentation is variable and adult…Abstract Number: 1932 • 2017 ACR/ARHP Annual Meeting
A2A Adenosine Receptor (A2AR) Stimulation Modulates NR4A2 Orphan Receptor Expression during Osteoclast Differentiation
Background/Purpose: Orphan receptors comprise a large number of evolutionarily conserved molecules that have unknown ligands but may have potent biologic effects. Among these receptors are…Abstract Number: 1948 • 2017 ACR/ARHP Annual Meeting
TNF-α Overrides the Ability of RANK Ligand to Induce Osteoclast Differentiation of Classical Circulating Precursors
Background/Purpose: TNF-α is well known to be involved in inflammatory-induced bone destruction. This is widely supported by clinical studies showing reduced bone pathology after anti-TNF-α…Abstract Number: 21 • 2017 Pediatric Rheumatology Symposium
Enhancing Quality of Care in Childhood-Onset Systemic Lupus Erythematosus by Improving Performance on Quality Indicator Measures in Cardiovascular and Bone Health
Background/Purpose: Childhood-onset SLE (cSLE) leads to poor health outcomes, including cardiovascular and bone health, due to high rates of potentially devastating disease complications and medication…Abstract Number: 356 • 2016 ACR/ARHP Annual Meeting
Osteoporotic Fracture As the Main Risk Factor in the Detection of Osteoporosis in Men Under 70 Years
Background/Purpose: Osteoporosis (OP) in males under 70 years is less common than postmenopausal and senile, but generates significant social and health costs associated with morbidity…Abstract Number: 1100 • 2016 ACR/ARHP Annual Meeting
Tenofovir, a Nucleoside Analog Reverse Transcriptase Inhibitor for Treatment of HIV, Promotes Osteoclast Differentiation and Decreases Osteoblast Formation By a Mechanism Depending on ATP Release and Adenosine
Background/Purpose: Human Immunodeficiency Virus (HIV) infection devastates the immune system but also affects tissues and organs such as kidney, liver, central nervous system, heart and…Abstract Number: 1987 • 2016 ACR/ARHP Annual Meeting
Recessive Coding and Regulatory Mutations in FBLIM1 Underlie the Pathogenesis of Sterile Osteomyelitis
Background/Purpose: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare, pediatric, autoinflammatory disease characterized by bone pain due to sterile osteomyelitis, and is often accompanied by…Abstract Number: 377 • 2015 ACR/ARHP Annual Meeting
Hand Bone Impairment By High-Resolution Peripheral Quantitative Computed Tomography in Patients with Diffuse Systemic Sclerosis: Correlation with Clinical Parameters, Quality of Life and Capillaroscopic Findings
Background/Purpose: Skin thickening and hand joint involvement induce bone loss and contribute to functional disability in patients with dcSSc. The high-resolution peripheral quantitative CT (HR-pQCT)…Abstract Number: 2089 • 2015 ACR/ARHP Annual Meeting
Netrin-1 and Its Receptors Unc5b and DCC May be Useful Targets for Preventing Multiple Myeloma Bone Lesions
Background/Purpose: Multiple Myeloma is characterized by the uncontrolled proliferation of plasma cells. This type of malignancy is particularly trophic to bone where it induces osteoclastic…Abstract Number: 2706 • 2015 ACR/ARHP Annual Meeting
3D Location of Erosions in an Early Rheumatoid Arthritis Population: An MRI Study Using Statistical Shape Models with Implications for Pathogenesis
Background/Purpose: Concepts of erosion pathogenesis in rheumatoid arthritis (RA) have been based on radiographs, although MR images are much better able to visualise erosions. Statistical…