Abstracts tagged "Bone density"

Abstract Number: 1354 • ACR Convergence 2020
The Effect of 8 Years of TNF-α Blocking Therapy on Bone Mineral Density in Patients with Ankylosing Spondylitis
Mark Siderius¹, Freke Wink¹, Anneke Spoorenberg¹ and Suzanne Arends¹, ¹University Medical Centre Groningen and Medical centre Leeuwarden, Groningen, Netherlands
Background/Purpose: Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly affects the axial skeleton. Bone loss reflected by low bone mineral density (BMD) is…
Abstract Number: 1588 • ACR Convergence 2020
A Quality Improvement Project to Improve Bone Densitometry Ordering in Adult Patients on Chronic Glucocorticoids
Katherine Kaufman¹, Philip Chu¹, Mithu Maheswaranathan¹, Andrew Johannemann¹, D Ryan Anderson¹, Isaac Smith¹, Akrithi Udupa¹, Mary Buckley¹, Laura Cannon¹, Rachel Randell¹ and David Leverenz¹, ¹Duke University, DURHAM, NC
Background/Purpose: The 2017 ACR guideline for glucocorticoid-induced osteoporosis (GIOP) recommends DXA testing in patients aged ≥40 years on chronic glucocorticoids. We performed a quality improvement…
Abstract Number: 0101 • ACR Convergence 2020
Romosozumab After Denosumab Improves Lumbar Spine and Maintains Total Hip Bone Mineral Density in Postmenopausal Women with Low Bone Mass
Michael R McClung¹, Michael A Bolognese², Jacques P Brown³, Jean-Yves Reginster⁴, Bente Langdahl⁵, Norma Ruiz-Santiago⁶, Yifei Shi⁶, Maria Rojeski⁶, Jen Timoshanko⁷, Cesar Libanati⁷, Helina Kassahun⁶ and Mary Oates⁶, ¹Oregon Osteoporosis Center, Portland, OR, ²Bethesda Health Research Center, Bethesda, MD, ³Laval University and CHU de Québec (CHUL) Research Centre, Québec City, Canada, ⁴University of Liège, Liège, Belgium, ⁵Aarhus University Hospital, Aarhus, Denmark, ⁶Amgen Inc., Thousand Oaks, CA, ⁷UCB Pharma, Brussels, Belgium
Background/Purpose: Romosozumab, an anti-sclerostin antibody that increases bone formation while decreasing bone resorption, reduces fracture risk within 12 months. Here we evaluate the effects of…
Abstract Number: 1591 • ACR Convergence 2020
A Quality Improvement Project to Increase Vitamin D Prescribing for Pediatric Patients on Glucocorticoids
Katherine Kaufman¹, Mary Buckley¹, Laura Cannon¹, Rachel Randell¹, Philip Chu¹, Mithu Maheswaranathan¹, Andrew Johannemann¹, D Ryan Anderson¹, Isaac Smith¹, Akrithi Udupa¹ and David Leverenz¹, ¹Duke University, DURHAM, NC
Background/Purpose: Chronic glucocorticoid treatment in children increases the risk of bone loss, fractures, and reduced adult skeletal mass. The 2017 ACR Glucocorticoid-Induced Osteoporosis (GIOP) guidelines…
Abstract Number: 0106 • ACR Convergence 2020
A Machine Learning-derived Radiomics Nomogram for Diagnosis of Osteoporosis and Osteopenia
Qianrong Xie¹, Yue Chen², Yimei Hu³, Fanwei Zeng⁴, Pingxi Wang⁴, Lin Xu⁵, Jianhong Wu⁶, Jie Li¹, Jing Zhu⁷, Ming Xiang⁸ and Fanxin Zeng⁹, ¹Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, China (People's Republic), ²Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), ³Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), ⁴Department of bone disease, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁵Department of medical imaging, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁶Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁷Department of Rheumatology and Immunology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, China (People's Republic), ⁸Department of Orthopedics, Sichuan Provincial Orthopedic Hospital, Chengdu, China (People's Republic), ⁹Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, Sichuan, China (People's Republic)
Background/Purpose: To discriminate osteoporosis and osteopenia using a quantitative computed tomography (QCT) radiomics signatures and clinical variables.Methods: This retrospective study enrolled 635 patients with QCT images and clinical characteristics from November…
Abstract Number: 1896 • ACR Convergence 2020
No Relationship Between Lumbar Bone Mineral Density and Syndesmophyte Formation at the Same Level – A Multilevel Analysis in Patients with Radiographic Axial Spondyloarthritis
Mary Lucy Marques¹, Sofia Ramiro², Pedro M Machado³, Désirée van der Heijde⁴ and Floris van Gaalen⁵, ¹Leiden University Medical Center, Coimbra, Portugal, ²Leiden University Medical Center, Bunde, Netherlands, ³University College London, London, United Kingdom, ⁴Leiden University Medical Center, Leiden, Netherlands, ⁵Leiden University Medical Center (LUMC), Leiden, Netherlands
Background/Purpose: In radiographic axial spondyloarthritis (r-axSpA) it has been hypothesized that inflammation-driven bone loss triggers bone repair but at anatomically distinct sites of the same…
Abstract Number: 0108 • ACR Convergence 2020
The Relationship Between Body Fat Percentage and Bone Mineral Density in Rheumatoid Arthritis Patients
Anastasia- Vasiliki Madenidou¹ and Marwan Bukhari², ¹Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Barrow-in-Furness, United Kingdom, ²Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom
Background/Purpose: Currently, Dual-Energy X-ray Absorptiometry (DEXA) scans are used to determine fracture risk by calculating Bone Mineral Density (BMD). It is well established that body…
Abstract Number: 1973 • ACR Convergence 2020
Treatment Sequences with Romosozumab Before or After Antiresorptive Medication
Felicia Cosman¹, David Kendler², Bente Langdahl³, Benjamin Z Leder⁴, E Michael Lewiecki⁵, Akimitsu Miyauchi⁶, Maria Rojeski⁷, Michele McDermott⁷, Mary Oates⁷, Cassandra E Milmont⁸, Cesar Libanati⁹ and Serge Ferrari¹⁰, ¹Columbia University, New York, NY, ²University of British Columbia, Vancouver, BC, Canada, ³Aarhus University Hospital, Aarhus, Denmark, ⁴Mass General Hospital, Harvard Medical School, Boston, MA, Boston, MA, ⁵New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, ⁶Miyauchi Medical Center, Osaka, Japan, ⁷Amgen Inc., Thousand Oaks, CA, ⁸Amgen Inc., Thousand Oaks, ⁹UCB Pharma, Brussels, Belgium, ¹⁰Geneva University Hospital, Geneva, Switzerland
Background/Purpose: Prior studies of anabolic/antiresorptive treatment sequences indicate that using teriparatide first followed by an antiresorptive results in greater bone mineral density (BMD) gains, particularly…
Abstract Number: 0112 • ACR Convergence 2020
Description of Risk Factors at Baseline and Need of Bone Agent According to Hadji Recommendations in Patients Taking Aromatase Inhibitors as Breast Cancer Therapy
David Montero-Seisdedos¹, Oihane Ibarguengoitia-Barrena², Lucía Vega-Álvarez², Carmen Lucía García Gomez², Itziar Calvo-Zorrilla³, Juan M. Blanco-Madrigal², Maria Esther Ruiz-Lucea², María Luz García-Vivar², Eva Galindez-Agirregoikoa², Ana R. Inchaurbe-Pellejero², Olaia Fernandez-Berrizbeitia², Clara E. Perez-Velasquez², Eduardo Cuende-Quintana⁴, Amaia Bilbao-González³ and Iñaki Torre-Salaberri³, ¹Basurto University Hospital, Bilbao, Pais Vasco, Spain, ²Basurto University Hospital, Bilbao, Spain, ³University Hospital of Basurto, Bilbao, Pais Vasco, Spain, ⁴Basurto University Hospital, Madrid, Spain
Background/Purpose: A well-known adverse effect of aromatase inhibitors (AI) in the bone is the loss of mineral density with the consequent increased risk of fracture…
Abstract Number: 1975 • ACR Convergence 2020
Predicting Bone Mineral Density of Lumbar Vertebrae by Assessing Plain Film with Deep Learning
Chen-I Hsieh¹, Chang-Fu Kuo¹, Shun Miao², Kang Zheng² and Le Lu², ¹Chang Gung Memorial Hospital, Taoyuan, Taiwan (Republic of China), ²PAII labs, Bethesda, MD
Background/Purpose: Osteoporosis is a silent disease characterized by a decrease in bone mineral density (BMD), causing bone fragility and increased risk of fracture. The most…
Abstract Number: 0114 • ACR Convergence 2020
Incidence of Follow-Up Dual-Energy X-Ray Absorptiometry Scanner Error: A Contributor to Precision Error
Kevin Lee¹, Karam Al Jumaily¹, Mu Lin², Kerry Siminoski³ and Carrie Ye⁴, ¹Internal Medicine, University of Alberta, Edmonton, AB, Canada, ²Alberta Health Services, Edmonton, AB, Canada, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Rheumatology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Osteoporosis is characterized by decreased bone tissue microarchitecture. This leads to reduced bone density and quality and is a significant contributor to morbidity, mortality,…
Abstract Number: 0115 • ACR Convergence 2020
Improving Osteoporosis Screening in Men at a Resident-run Primary Care Clinic: A Quality Improvement Project
Khiem Vu¹, Chima Ohadugha¹, Kevin Dao¹, Rabih Nayfe² and Andrew Mangano¹, ¹Grand Strand Medical Center, Myrtle Beach, SC, ²Carolina Health Specialists - Rheumatology, Myrtle Beach, SC
Background/Purpose: There are known indications for osteoporosis screening in women. However, osteoporosis also occurs in men and fragility fractures are linked to increased morbidity and…
Abstract Number: 0125 • ACR Convergence 2020
A Resident-Led Interdisciplinary Quality Improvement Initiative to Increase Osteoporosis Screening in an Urban Clinic
Catherine Teskin¹ and Hiba Sayed², ¹Christiana Care, Wilmington, ²Christiana Care, wilmington, DE
Background/Purpose: Osteoporosis is a major cause of morbidity and mortality in the United States. The USPSTF recommends screening all women age 65 and older or…
Abstract Number: 0128 • ACR Convergence 2020
Short-Term Monitoring of Denosumab Effect in Breast Cancer Patients Receiving Aromatase Inhibitors Using Radiofrequency Echographic Multi-Spectrometry (REMS) Technology on Femoral Neck
Rosachiara Forcignanò¹, Fiorella Anna Lombardi², Mariangela Ciccarese³, Eugenio Quarta⁴, Antonella Grimaldi⁵, Laura Quarta⁵, Delia Ciardo², Ernesto Casciaro², Paola Pisani², Francesco Conversano², Maurizio Muratore⁵ and Sergio Casciaro², ¹O.U. of Oncology, “Sacro Cuore di Gesù” Hospital, Gallipoli, Lecce, Italy, Gallipoli, Italy, ²National Research Council, Institute of Clinical Physiology, Lecce, Italy, Lecce, Italy, ³O.U. of Oncology, “Vito Fazzi” Hospital, ASL-LE, Lecce, Italy, Lecce, Italy, ⁴O.U. of Rheumatology, "Galateo" Hospital, ASL-LE, San Cesario di Lecce, Lecce, Italy, San Cesario di Lecce, Italy, ⁵O.U. of Rheumatology, “Galateo” Hospital, San Cesario di Lecce ASL-LE, Lecce, Italy, San Cesario di Lecce, Italy
Background/Purpose: The aim of the study was to carry out a short-term monitoring of the effect of aromatase inhibitors (AI) and Denosumab on bone health…
Abstract Number: 0129 • ACR Convergence 2020
Glucocorticoid-Induced Osteoporosis in Patients with Chronic Inflammatory Rheumatic Diseases: A Multivariate Linear Regression Analysis Identifying Factors Affecting Bone Mineral Density
Edgar Wiebe¹, Desiree Freier¹, Dörte Huscher², Sandra Hermann¹, Robert Biesen³ and Frank Buttgereit⁴, ¹Charité University Medicine Berlin, Dep. of Rheumatology and Clinical Immunology, Berlin, Germany, ²Charité University Medicine Berlin, Dep. of Biometry and Clinical Epidemiology, Berlin, Germany, ³Charité University Medicine, Dep. of Rheumatology and Clinical Immunology, Berlin, ⁴Charité University Medicine, Berlin, Germany
Background/Purpose: Rheumatic diseases are associated with increased systemic bone loss and fracture risk related to chronic inflammation, disease-specific, general and demographic risk factors as well…

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