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Abstracts tagged "Biomechanics"

  • Abstract Number: 2002 • 2018 ACR/ARHP Annual Meeting

    Dynamic Compression of Articular Cartilage Explants Increases Formation and Decreases Degradation of Type II Collagen

    Amalie Engstrøm1,2, Anne C. Bay-Jensen2, Morten A. Karsdal2 and Christian S. Thudium2, 1Department of Biomedical Science, University of Copenhagen, København, Denmark, 2Nordic Bioscience, Herlev, Denmark

    Background/Purpose: Mechanical loading is recognized as a major factor in initiation and progression of osteoarthritis (OA). Conversely loading is believed to play an essential role…
  • Abstract Number: 2765 • 2017 ACR/ARHP Annual Meeting

    Centre of Pressure Characteristics during Walking in Individuals with and without First Metatarsophalangeal Joint Osteoarthritis

    Hylton Menz1, Maria Auhl2, Jade Tan2 and Shannon Munteanu1, 1La Trobe University, Bundoora, Australia, 2School of Allied Health, La Trobe University, Bundoora, Australia

    Background/Purpose: Osteoarthritis of the first metatarsophalangeal joint (1st MTPJ OA) is a common and disabling condition characterised by symptoms of joint pain and stiffness, formation of…
  • Abstract Number: 652 • 2017 ACR/ARHP Annual Meeting

    Investigating the Role of Mechanical Stress in Spondyloarthritis Pathogenesis

    Breanna Nguyen1, Robert Colbert2 and Gerlinde Layh-Schmitt1, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 2NIAMS/NIH, Bethesda, MD

    Background/Purpose: Mechanotransduction is a cell’s ability to translate mechanical stimuli into biochemical signals and has been implicated in signaling pathways involving differentiation and proliferation. Mechanical…
  • Abstract Number: 2185 • 2017 ACR/ARHP Annual Meeting

    Relation of Foot Pronation to Medial Knee Load in Persons with Medial Knee Osteoarthritis

    K. Douglas Gross1, Richard Jones2, David T. Felson3, Salinda Chong4 and Howard J. Hillstrom5, 1Physical Therapy, MGH Institute of Health Professions, Boston, MA, 2School of Health Sciences, University of Salford, Manchester, United Kingdom, 3Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, 4MGH Institute of Health Professions, Boston, MA, 5Rehabilitation, Hospital Special Surgery (HSS), New York, NY

    Background/Purpose: The knee adduction moment (KAM) estimates medial knee load during gait, with high KAM fueling worsening OA. Understanding how foot mechanics contribute to KAM…
  • Abstract Number: 291 • 2016 ACR/ARHP Annual Meeting

    Relation of Foot Pronation during Walking to Risk of Worsening Lateral Patellofemoral and Medial Tibiofemoral Cartilage Damage

    K. Douglas Gross1,2, Howard J. Hillstrom3, Carrie Brown4, Richard Jones5, Joshua Stefanik6, Michael C. Nevitt7, Cora E. Lewis8, James Torner9 and David T. Felson2, 1Physical Therapy, MGH Institute of Health Professions, Boston, MA, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Rehabilitation, Hospital Special Surgery (HSS), New York, NY, 4Boston University School of Public Health, Boston, MA, 5School of Health Sciences, University of Salford, Manchester, United Kingdom, 6Physical Therapy, Northeastern University, Boston, MA, 7Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 8Preventive Medicine, University of Alabama at Birmingham, Birmingham City, AL, 9Epidemiology, University of Iowa, Iowa City, Iowa City, IA

    Background/Purpose: Foot pronation can lead to lateral patellofemoral (PF) maltracking with reduced tibiofemoral (TF) varum, inciting speculation that the highly pronated foot reported in knees…
  • Abstract Number: 359 • 2016 ACR/ARHP Annual Meeting

    The Association of Scheuermann’s Disease with Osteoporotic Vertebral Fracture Risk

    Marine Gaudé1, R Chapurlat2 and Pawel Szulc3, 1Rheumatology, INSERM UMR 1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, 2INSERM UMR 1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, 3Epidemiology of Osteoporosis, INSERM UMR 1033, Lyon, France

    Background/Purpose: Scheuermann’s disease is one of the most frequent illnesses of the spine in teenagers. Its evolution over time is poorly understood. Spinal deformities, by…
  • Abstract Number: 1307 • 2016 ACR/ARHP Annual Meeting

    Anatomical Patterns Suggest the Involvement of Biomechanical Stress in the Pathogenesis of Erosions in Rheumatoid Arthritis

    Matthew A. Jessome1, Michael A. Tomizza1, Karen A. Beattie2, William G. Bensen2, Raja S. Bobba2, Alfred Cividino2, Patrick D. Emond2, Chris Gordon2, Lawrence Hart2, Maggie Larche2, Arthur Lau3, Ruben Tavares2, Stephen Tytus2 and Jonathan D. Adachi2, 1Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, 2St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 350 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: There is limited data outlining the anatomic characteristics of bone erosions of the small joints in rheumatoid arthritis (RA). In particular, there is minimal…
  • Abstract Number: 1005 • 2015 ACR/ARHP Annual Meeting

    Association of Baseline Knee Sagittal Dynamic Joint Stiffness during Gait and 2-Year Cartilage Damage Progression in Knee Osteoarthritis (OA)

    Alison H. Chang1, Joan S. Chmiel2, Orit Almagor3, Kirsten C. Moisio3, Laura Belisle3, Yunhui Zhang3, Karen W. Hayes4 and Leena Sharma5, 1PT & Human Movement Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Department of Physical Therapy and Human Movement Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose:   While patellofemoral (PF) OA has been found to have substantial impact on pain and function, most studies continue to focus on tibiofemoral (TF)…
  • Abstract Number: 2389 • 2015 ACR/ARHP Annual Meeting

    Relation of Pronated Foot Posture to Risk of Worsening Knee Pain during Gait and Compartment-Specific Knee Cartilage Damage

    K. Douglas Gross1,2, Howard J. Hillstrom3, Emily K. Quinn4, Michael C. Nevitt5, Cora E. Lewis6, James Torner7 and David T. Felson2, 1Physical Therapy, MGH Institute of Health Professions, Boston, MA, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Rehabilitation, Hospital for Special Surgery, New York, NY, 4Clinical Epidemiology Unit, Boston University, Boston, MA, 5Epidemiology and Biostatistics, UCSF, San Francisco, CA, 6Preventive Medicine, University of Alabama, Birmingham, AL, 7Epidemiology, University of Iowa, Iowa City, IA

    Background/Purpose: Pronated foot posture is prevalent in older adults with knee cartilage damage and younger adults with knee pain. Yet, there is disagreement about the…
  • Abstract Number: 2390 • 2015 ACR/ARHP Annual Meeting

    Foot Kinematics and Foot Center of Pressure and Their Association with Medial Knee Load Reduction with Use of Flexible Shoes in Knee Osteoarthritis

    Chris Ferrigno1, Roy H. Lidtke2, Markus A. Wimmer3, Laura E. Thorp4, Joel A. Block5 and Najia Shakoor2, 1Anatomy, Rush University, Chicago, IL, 2Rheumatology, Rush University Medical Center, Chicago, IL, 3Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 4Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL, 5Rush University Medical Center, Chicago, IL

    Background/Purpose: Biomechanical treatments for medial knee osteoarthritis (OA) often target the knee adduction moment (KAM).  Foot-mediated biomechanical interventions for knee OA may operate through altering…
  • Abstract Number: 2945 • 2014 ACR/ARHP Annual Meeting

    Foot Structure and Function Show Associations with Lower Extremity Physical Function

    Yvonne M. Golightly1, Marian T. Hannan2, Patricia P. Katz3, Howard J. Hillstrom4, Alyssa B. Dufour5 and Joanne M. Jordan6, 1Gillings School of Global Public Health, Dept of Epidemiology, Thurston Arthritis Research Center, Injury Prevention Research Center, University of North Carolina Dept of Epidemiology, Chapel Hill, NC, 2Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 3Medicine, University of California, San Francisco, San Francisco, CA, 4Rehabilitation, Hospital Special Surgery (HSS), New York, NY, 5Institute for Aging Research, Hebrew SeniorLife & Boston Univ, Boston, MA, 6University of North Carolina Dept of Epidemiology, Chapel Hill, NC

    Background/Purpose . Foot pain is associated with poorer physical function in older adults, but few studies have examined how foot structure (high / low arches) and…
  • Abstract Number: 2861 • 2014 ACR/ARHP Annual Meeting

    Changes in Knee Kinematics from a 6-Week Hip and Trunk Strengthening Program for Persons with Patellofemoral Osteoarthritis

    Lisa Hoglund1, Laura Pontiggia2, John Kelly IV3, Mark Arnott4, Olumide Babalola4, Andrew Gushen4 and James Carey3, 1Department of Physical Therapy, University of the Sciences, Philadelphia, PA, 2Mathematics, Physics, and Statistics, University of the Sciences, Philadelphia, PA, 3Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, 4Physical Therapy, University of the Sciences, Philadelphia, PA

    Background/Purpose: Patellofemoral (PF) osteoarthritis (OA) is prevalent in middle-aged adults. Aberrant lower extremity (LE) biomechanics is one etiology of knee OA. Reduced peak knee flexion…
  • Abstract Number: 2245 • 2014 ACR/ARHP Annual Meeting

    Characteristics of Conventional Footwear and Their Association with Reductions in Knee Loading with a Flexible Footwear Intervention

    Najia Shakoor1, Roy H. Lidtke2, Chris Ferrigno3, Anjali Nair2, Markus A. Wimmer4, Laura E. Thorp5, K. Douglas Gross6 and Joel A. Block2, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Section of Rheumatology, Rush University Medical Center, Chicago, IL, 3Anatomy, Rush University, Chicago, IL, 4Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 5Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL, 6Clinical Epidem Rsrch, Boston Univ School Medicine, Boston, MA

    Background/Purpose: The peak external knee adduction moment (KAM) as measured through gait analyses has been associated with severity, progression and pain in medial knee osteoarthritis (OA);…
  • Abstract Number: 973 • 2014 ACR/ARHP Annual Meeting

    Relation of Pelvic Drop during Walking to Risk of Incident Medial Knee Osteoarthritis: The Multicenter Osteoarthritis Study

    K. Douglas Gross1,2, Emily K. Quinn3, Michael C. Nevitt4, James C. Torner5, Cora E. Lewis6 and David T. Felson7, 1Physical Therapy, MGH Institute of Health Professions, Boston, MA, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Unit, Boston University, Boston, MA, 4Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 5Epidemiology, University of Iowa, Iowa City, Iowa City, IA, 6Preventive Medicine, The University of Alabama at Birmingham, Birmingham, AL, 7Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: During walking, the contralateral pelvis tends to drop as the weight bearing limb enters midstance. If excessive, pelvic drop (PD) can result in increased…
  • Abstract Number: 212 • 2014 ACR/ARHP Annual Meeting

    Relation of Shoe Stability to Risk of Knee Cartilage Damage: The Multicenter Osteoarthritis Study

    K. Douglas Gross1,2, Howard J. Hillstrom3, Jingbo Niu4, Michael C. Nevitt5, James C. Torner6, Cora E. Lewis7 and David T. Felson2, 1Physical Therapy, MGH Institute of Health Professions, Boston, MA, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Rehabilitation, Hospital Special Surgery (HSS), New York, NY, 4Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, 5Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 6Epidemiology, University of Iowa, Iowa City, Iowa City, IA, 7Preventive Medicine, The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Clinical guidelines recommend that “every patient with knee osteoarthritis should receive advice concerning appropriate footwear”, yet the recommended content of this advice is not…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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