Abstract Number: 1274 • 2013 ACR/ARHP Annual Meeting
Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus
Background/Purpose: Women with anti-Ro antibodies face the risk of having a child with cardiac Neonatal Lupus (NL), characterized by congenital heart block and/or cardiomyopathy. Biomarkers…Abstract Number: 313 • 2013 ACR/ARHP Annual Meeting
The DC-STAMP+IL17A+ Cell Subset Is Elevated In Psoriatic Arthritis (PsA) Patients and Declines Following Anti-TNFi Therapy
Background/Purpose: Approximately 25% of psoriasis (Ps) patients develop psoriatic arthritis (PsA), a potentially destructive joint disease, within 10 years of Ps onset. Although early diagnosis…Abstract Number: 71 • 2013 ACR/ARHP Annual Meeting
Subchondral Bone Turnover and Osteophyte Formation Are Key Aspects In The Progression Of Osteoarthritis and May Be Assessed and Predicted By a-CTX
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritic disease. It is characterized by pathological changes in both bone and cartilage turnover as well…Abstract Number: 2263 • 2013 ACR/ARHP Annual Meeting
ADAMTS5 Is a Biomarker For The Efficacy Prediction Of Tocilizumab In Rheumatoid Arthritis
a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5) mRNA level. In this study presented here, we investigated whether the efficacy of tocilizumab (TCZ) for…Abstract Number: 1845 • 2013 ACR/ARHP Annual Meeting
Soluble Type I Interferon Receptor 2 Is Elevated By Interferon Treatment and In Certain Autoimmune Diseases
Background/Purpose: The Type I Interferon (IFN) receptor is a heterodimer of chain 1 (IFNAR1) which is required for signaling, and chain 2 (IFNAR2) which binds…Abstract Number: 1250 • 2013 ACR/ARHP Annual Meeting
Serological Markers Of Structural Integrity and Inflammation Is Associated With Pain In Osteoarthritis
Background/Purpose: Pain is associated with diagnosed osteoarthritis (OA), but little clinically association is found between joint integrity and the pain the individual patient experience. Peripheral…Abstract Number: 245 • 2013 ACR/ARHP Annual Meeting
C-Reactive Protein But Not Erythrocyte Sedimentation Rate Is Associated With Decrease In Muscle Strength In Patients With Knee Osteoarthritis: A 2 Year Follow Up Study
Background/Purpose: In patients with knee osteoarthritis activity limitations and disease progression have been associated with muscle weakness (OA). Muscle weakness might be determined by factors…Abstract Number: 2902 • 2013 ACR/ARHP Annual Meeting
Key Roles For Interferon and Macrophage Activation In Progressive Lung Fibrosis Associated With Systemic Sclerosis
Background/Purpose: Interstitial lung disease associate with Systemic Sclerosis(SSc-ILD) is one of the leading causes of mortality. We analyzed the gene expression of lung tissue in…Abstract Number: 2262 • 2013 ACR/ARHP Annual Meeting
Antibody To Malondialdehyde-Acetaldehyde Adducts (MAA) Is a Biomarker Of Inflammation and Is Correlated With The Disease Activity In Rheumatoid Arthritis
Background/Purpose: Cardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with rheumatoid arthritis (RA). While there are many markers used…Abstract Number: 1809 • 2013 ACR/ARHP Annual Meeting
Topline Results Of The Biomarkers Of Lupus Disease (BOLD) Study: Clinical and Mechanistic Perplexities Of Lupus Treatment Trials Can Be Mitigated By Eliminating Background Immune Suppressants
Background/Purpose: The BOLD study was designed to test the discriminatory capacity and safety of a trial design eliminating background immune suppressants (IS) in SLE patients…Abstract Number: 1253 • 2013 ACR/ARHP Annual Meeting
Studies On The Relationship Between Intraplantar Carrageenan-Induced Bradykin B1 Receptor Messenger Ribonucleic Acid Expression and Oedema and Hyperalgesia In Rats: Effects Of Dexamethasone and a B1 Receptor Antagonist, BI-113823
Background/Purpose: Kinins are a group of peptides formed in plasma and tissues in response to infection, tissue trauma or inflammation (inflamm) whose actions are mediated…Abstract Number: 248 • 2013 ACR/ARHP Annual Meeting
Hand Osteoarthritis Is Associated With Increased Type II Collagen Degradation In Women: The Ofely Study
Background/Purpose: Hand osteoarthritis (OA) is one of the most common sites of OA and predominantly affects women. Patients with knee, hip or spine OA exhibit…Abstract Number: 2914 • 2013 ACR/ARHP Annual Meeting
Serum Proteins and Whole Blood Transcripts Suppressed By An Anti-Type I Interferon Receptor Monoclonal Antibody In Subjects With Systemic Sclerosis
Background/Purpose: To identify serum markers that are modulated by an investigational human IgG1κ monoclonal antibody directed against subunit 1 of the type I interferon receptor…Abstract Number: 2205 • 2013 ACR/ARHP Annual Meeting
Galectin-3 and Transforming Growth Factor-β Signaling In The Pathogenesis Of Coronary Artery Aneurysms In Kawasaki Disease
Background/Purpose: Kawasaki disease (KD) is a self-limited acute vasculitis of young children, and coronary artery aneurysms (CAA) are the most significant complication. Despite appropriate treatment…Abstract Number: 1777 • 2013 ACR/ARHP Annual Meeting
Antibodies Against TIF1-Gamma In Cancer Associated Myositis May Precede Cancer Symptoms and Persist After Cancer Removal
Background/Purpose: Antibodies against TIF1-gamma have been detected in patients with cancer associated myositis (CAM) but it is not known whether the antibodies precede the diagnosis…
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