ACR Meeting Abstracts

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Abstracts tagged "Behcet’s syndrome"

  • Abstract Number: 3044 • 2015 ACR/ARHP Annual Meeting

    Microparticles (MPs) Derived from Cell Plasma Membranes Are Increased in Behcet’s Syndrome (BS) and a Low Ratio of Tissue Factor Pathway Inhibitor Positive Mps to Tissue Factor Positive Mps (TFPI/TF) Is Associated with Thrombosis

    Emon Khan1, Nicola Ambrose1, Miles Stanford2, Michael A. Laffan3 and Dorian O. Haskard4, 1Department of Vascular Sciences, National Heart and Lung Institute, Imperial College, London, United Kingdom, 2Ophthalmology, Guy's and St. Thomas' Hospital, London, United Kingdom, 3Department of Haemostasis and Thrombosis, Imperial College, London, United Kingdom, 4Rheumatology, Imperial College, London, United Kingdom

    Background/Purpose: Thrombosis occurs in around 20% of Behçet's Syndrome (BS) patients and causes substantial morbidity.  There is a clear need for better biomarkers of thrombotic…
  • Abstract Number: 3045 • 2015 ACR/ARHP Annual Meeting

    Anti-Alpha-Enolase Antibodies in Behçet’s Disease: A Marker of Articular Disease Activity?

    Leandro L. Prado, Celio R. Gonçalves, Vilma S. T. Viana, Eloisa Bonfá and Carla G.S. Saad, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Diagnosis of Behçet´s disease (BD) is challenging because is based solely on clinical features. Articular involvement in this disease may mimic other diagnosis such…
  • Abstract Number: 204 • 2015 ACR/ARHP Annual Meeting

    Histone Methylation Profiling in Peripheral White Blood Cells As a Candidate Biomarker for Behcet’s Disease

    Yoshimi Aizaki1,2, Yasuto Araki1,2, Kojiro Sato1, Yuji Akiyama1 and Toshihide Mimura1,2, 1Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, 2Project Research Division, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan

    Background/Purpose: Behcet’s disease (BD) is a chronic recurrent, multisystem inflammatory disorder. The phenotypic characteristics include oral aphtha, genital ulcers, uveitis and skin lesions. No specific…
  • Abstract Number: 3046 • 2015 ACR/ARHP Annual Meeting

    Venous Disease-Specific Quality-of-Life Is Impaired in Patients with Vascular Behcet’s Disease

    Fatma Alibaz-Oner1, Belgin Aldag2, Mustafa Aldag3, Ali Ugur Unal4, Tayfur Toptas5, Tülin Ergun6 and Haner Direskeneli4, 1Department Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 3Dr.Siyami Ersek Cardiovascular Surgery Hospital,, Istanbul, Turkey, 4Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 5Hematology, Marmara University, Istanbul, Turkey, 6Dermatology, Marmara University Faculty of Medicine, Dermatology, Istanbul, Turkey

    Background/Purpose: Vascular involvement is seen in up to 40% of the patients with Behcet's disease (BD), with lower extremity deep vein thrombosis (DVT) as the most…
  • Abstract Number: 1247 • 2015 ACR/ARHP Annual Meeting

    Methylation Analysis of HLA-B Locus in Familial Behçet Syndrome

    Eda Tahir Turanli1, Pelinsu Koprulu2, Serdal Ugurlu3, Hasan Yazici4 and Emire Seyahi3, 1Molecular Biology and Genetics Department, Istanbul Technical University, Istanbul, Turkey, 2Molecular Biology Genetics and Biotechnology Program, Istanbul Technical University, Istanbul, Turkey, 3Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, 4Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: Our focus has been on the potential role of the epigenetic processes, mainly of the methylation, on the development of Beh�et syndrome (BS) using…
  • Abstract Number: 3049 • 2015 ACR/ARHP Annual Meeting

    Cognitive Dysfunction in Chronic Progressive Neuro-Behçet’s Disease: Comparative Study of the Brainstem and Hippocampus Region Using Brain Magnetic Resonance Imaging

    Hirotoshi Kikuchi1, Kurumi Asako1, Maki Takayama1, Shoko Iga1, Yoshitaka Kimura1, Hajime Kono1 and Shunsei Hirohata2, 1Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 2Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan

    Background/Purpose: Central nervous system involvement is one of the most serious complications in Behçet's disease (BD). This condition is referred to as neuro-Behçet's disease (NB)…
  • Abstract Number: 1370 • 2015 ACR/ARHP Annual Meeting

    CD40/CD40L Pathway Is Associated with Increased Oxidative Burst and Neutrophil Extracellular Traps Release in Behcet´s Disease

    Sandro F. Perazzio1,2, Paulo Vitor Soeiro Pereira3, Alexandre W.S. Souza4, Antonio Condino-Neto3 and Luis Eduardo C. Andrade5, 1Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Fleury Medicine and Health, Sao Paulo, Brazil, 3Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, 5Immunology Division, Fleury Medicine and Health, São Paulo, Brazil

    Background/Purpose: Previous studies suggested that unknown plasma factors increase oxidative burst in Behçet’s disease (BD), but little is known about neutrophil extracellular traps (NET) formation.…
  • Abstract Number: 3052 • 2015 ACR/ARHP Annual Meeting

    Budd-Chiari Syndrome in Behçet’s Disease:a Retrospective Multicenter Study

    Lutfi Akyol1, Bahtiyar Toz2, Ozun Bayndır3, Orhan Zengin4, Dondu Uskudar Cansu5, Murat Yigit6, Gozde Yildirim Cetin7, Ahmet Omma8, Abdulsamet Erden9, Orhan Kucuksahin10, Senol Kobak11, Osman Cure1, Ali Ugur Unal12, Ayten Yazici13, Metin Ozgen1, Ali Sahin14, Emel Gonullu15, Suleyman Serdar Koca16, Burak Erer2, Ahmet Gul17, Kenan Aksu3, Gokhan Keser18, Ahmet Mesut Onat4, Bunyamin Kisacik4, Timucin Kasifoglu5, Ayse Cefle19, Umut Kalyoncu9 and Mehmet Sayarlioglu1, 1Department of Internal Medicine Division of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey, 2Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 3İnternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 4İnternal Medicine Division of Rheumatology, Gaziantep University, Faculty of Medicine, Gaziantep, Turkey, 5İnternal Medicine Division of Rheumatology, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey, 6İnternal Medicine Division of Rheumatology, Pamukkale University, Faculty of Medicine, Denizli, Turkey, 7Rheumatology, Kahramanmaras University School of Medicine, Kahramanmaras, Turkey, 8Department of Internal Medicine, Rheumatology Division, Ankara Numune Hospital, Ankara, Turkey, 9Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 10Rheumatology, Yildirim Beyazit University School of Medicine, Ankara, Turkey, 11Rheumatology, Sifa University, Izmir, Turkey, 12Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 13Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey, 14Department of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey, 15Rheumatology, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey, 16İnternal Medicine Division of Rheumatology, Firat University, Faculty of Medicine, Elazig, Turkey, 17Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 18Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 19İnternal Medicine Division of Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey

    Background/Purpose: Budd-Chiari syndrome (BCS), or hepatic venous outflow obstruction, is a rare and serious complication of Behçet's disease (BD). The aim of this study was…
  • Abstract Number: 2744 • 2014 ACR/ARHP Annual Meeting

    Mi-RNA Profile of Active Vascular BEHÇET’S Patients

    Ahmet Mesut Onat1, Ozan Gerenli2, Bunyamin Kisacik1, Mustafa Ulasli3, Gezmis Kimyon4, Yavuz Pehlivan5 and Serdar Oztuzcu6, 1Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 2Rheumatology, Gaziantep UniversitySchool of Medicine, Gaziantep, Turkey, 3Genetics, Gaziantep UniversitySchool of Medicine, Gaziantep, Turkey, 4Department of Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 5Rheumatology, Uludag University, School of Medicine, Bursa, Turkey, 6Genetcs, Gaziantep UniversitySchool of Medicine, Gaziantep, Turkey

    Background/Purpose Behçet’s Disease (BD) is a systemic vasculitis that predominantly presented with oral aphtous ulcers and additionally at least two of the following findings like…
  • Abstract Number: 2745 • 2014 ACR/ARHP Annual Meeting

    Plasma of Patients with Active Behçet´s Disease (BD) Increases Neutrophil Extracellular Trap Formation, Oxidative Metabolism and NADPH-Oxidase Expression in Normal and BD Neutrophils, and Carries Several Neutrophil Stimulating Factors

    Sandro F. Perazzio1,2, Paulo Vitor Soeiro Pereira3, Alexandre W. S. de Souza1, Antonio Condino-Neto3 and Luis Eduardo C. Andrade2,4, 1Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Fleury Medicine and Health, Sao Paulo, Brazil, 3Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 4Fleury Laboratories, Sao Paulo, Brazil

    Background/Purpose Plasma factors seem to play a role in Behçet’s disease (BD) pathogenesis, especially by increasing phagocyte oxidative profile. No data exists regarding neutrophil extracellular…
  • Abstract Number: 2747 • 2014 ACR/ARHP Annual Meeting

    Identification of Potential Serum Biomarkers for Behcet Disease By High Resolution Quantitative Proteomic Analysis

    Yongjing CHENG Jr.1, Xiaolin Sun2, Yuling Chen Jr.3, Cibo Huang4, Haiteng Deng3 and Zhan-Guo Li5, 1Rheumatology and Immunology Department, Beijing Hospital, Ministry of Health, Beijing, China, 2People's hospital,Peking University, Beijing, China, 3Tsing hua University, Beijing, China, 4Beijing hospital, Beijing, China, 5Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China

    Background/Purpose: Behcet’s disease (BD) is a chronic, multisystemic vasculitis, pathogenesis of BD remains enigmatic. Diagnosis of BD is sometimes difficult, and until now, no specific…
  • Abstract Number: 2748 • 2014 ACR/ARHP Annual Meeting

    Microparticles May Play a Role in Causing Thrombosis in Behçet’s Syndrome and Act As a Biomarker for Risk Management

    Emon Khan1, Nicola Ambrose1, Michael A. Laffan2 and Dorian O. Haskard3, 1Department of Vascular Sciences, National Heart and Lung Institute, Imperial College, London, United Kingdom, 2Department of Haemostasis and Thrombosis, Imperial College, London, United Kingdom, 3Rheumatology, Imperial College, London, United Kingdom

    Background/Purpose Thrombosis occurs in 20% of patients with Behçet’s Syndrome (BS) and leads to significant morbidity. There is no robust association between thrombosis in BS…
  • Abstract Number: 2749 • 2014 ACR/ARHP Annual Meeting

    The Clinical Course of Acute Deep Vein Thrombosis of the Legs in Behçet’s Syndrome

    Melike Melikoglu1, Yesim Ozguler2, Serdal Ugurlu3, Firat Cetinkaya4, Koray Tascilar2, Emire Seyahi3, Vedat Hamuryudan3 and Hasan Yazici1, 1Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 2University of Istanbul, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 3Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 4Radiology, Colormed Radiology Center, Istanbul, Turkey

    Background/Purpose To determine the prospective clinical course of lower extremity deep vein thrombosis (LEDVT) in patients with Behçet’s syndrome (BS).  Methods Consecutive BS patients with…
  • Abstract Number: 2750 • 2014 ACR/ARHP Annual Meeting

    Effects of Anticoagulant Treatment on the Incidence of New Vascular Events in Patients with Behcet’s Disease with Vascular Involvement

    Fatma Alibaz-Oner1, Aslı Karadeniz2, Sema Yilmaz3, Ayse Balkarli4, Gezmis Kimyon5, Ayten Yazici6, Muhammed Cinar7, Sedat Yilmaz7, Fatih Yildiz8, Sule Yasar Bilge9, Emre Bilgin10, Belkıs Nihan Şeniz11, Ahmet Omma12, Gozde Yildirim Cetin13, Yonca Cagatay14, Mehmet Sayarlioglu15, Yavuz Pehlivan16, Umut Kalyoncu17, Omer Karadag10, Timucin Kasifoglu9, Eren Erken8, Salih Pay7, Ayse Cefle6, Bunyamin Kisacik18, Ahmet Mesut Onat19, Veli Cobankara20 and Haner Direskeneli1, 1Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Internal Medicine, Marmara University, School of Medicine, Istanbul, Turkey, 3Department of Rheumatology, Selcuk University School of Medicine, Konya, Turkey, 4Department of Rheumatology, Pamukkale University School of Medicine, Denizli, Turkey, 5Department of Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 6Department of Rheumatology, Kocaeli University, Kocaeli, Turkey, 7Rheumatology, Gulhane Military Medical Academy, Ankara, Turkey, 8Rheumatology, Cukurova University, School of Medicine, Adana, Turkey, 9Rheumatology, Eskisehir Osmangazi University School of Medicine, Eskisehir, Turkey, 10Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 11Rheumatology, Uludağ University, School of Medicine, Bursa, Turkey, 12Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 13Rheumatology, Kahramanmaras University School of Medicine, Kahramanmaras, Turkey, 14Department of Rheumatology, Bilim University Faculty of Medicine, Istanbul, Turkey, 15Rheumatology, Ondokuz Mayis University School of Medicine, Samsun, Turkey, 16Rheumatology, Uludag University, School of Medicine, Bursa, Turkey, 17PsAID taskforce, EULAR, Zurich, Switzerland, 18Rheumatology, Gaziantep University, School of Medicine, Gaziantep, Turkey, 19Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 20Rheumatology, Pamukkale University, School of Medicine, Denizli, Turkey

    Background/Purpose: Vascular involvement (VI) is one of the major causes of mortality and morbidity in Behcet's Disease (BD). There are no controlled studies for the…
  • Abstract Number: 2751 • 2014 ACR/ARHP Annual Meeting

    18F-FDG PET/CT in Vascular Disease Due to Behçet’s Syndrome

    Emire Seyahi1, Metin Hallac2, Betul Vatankulu3, Serdal Ugurlu1, Melike Melikoglu4, Sebahattin Yurdakul1 and Hasan Yazici4, 1Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 2Department of Nuclear Medicine, Cerrahpasa Medical Faculty, University Of Istanbul, Istanbul, Turkey, 3Department of Nuclear Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 4Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey

    Background/Purpose 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT is considered as a useful tool in assessing active vascular inflammation in large vessel vasculitis. Lower extremity vein…
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