Behcet's syndrome Archives - ACR Meeting Abstracts

Abstract Number: 016 • 2020 Pediatric Rheumatology Symposium
Genetic Susceptibility Loci for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome
Kalpana Manthiram¹, Silvia Preite ², Fatma Dedeoglu ³, Selcan Demir ⁴, Seza Ozen ⁵, Kathryn Edwards ⁶, Sivia Lapidus ⁷, Alexander Katz ², Henry Feder ⁸, Maranda Lawton ³, Greg Licameli ³, Peter Wright ⁹, Karyl Barron ², Amanda Ombrello ², Beverly Barham ², Tina Romeo ¹⁰, Anne Jones ¹¹, Hemalatha Srinivasalu ¹², Pamela Mudd ¹², Roberta DeBiasi ¹², Ahmet Gul ¹³, Gary Marshall ¹⁴, Olcay Jones ¹⁵, Yuriy Stepanovskiy ¹⁶, Polly Ferguson ¹⁷, Pamela Schwartzberg ², Elaine Remmers ² and Daniel Kastner ¹⁸, ¹National Institutes of Health, Bethesda, Maryland, ²National Institutes of Health, Bethesda, ³Boston Children's Hospital, Boston, ⁴Hacettepe University, Division of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Ankara, Turkey, ⁵Hacettepe University, Division of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, ⁶Vanderbilt University School of Medicine, Nashville, ⁷The Joseph M. Sanzari Children's Hospital, Hackensack Meridian Health, Maplewood, ⁸Connecticut Children's Medical Center, Hartford, ⁹Dartmouth-Hitchcock Medical Center, Lebanon, ¹⁰NIH, Bethesda, ¹¹Bethesda, ¹²Children's National Medical Center, Washington, ¹³Istanbul University, Istanbul, Turkey, ¹⁴University of Louisville School of Medicine, Louisville, ¹⁵Walter Reed National Military Medical Center, Bethesda, ¹⁶Shupyk National Medical Academy of Postgraduate Education, Kiev, ¹⁷University of Iowa Carver College of Medicine, Iowa City, ¹⁸National Human Genome Research Institute, Bethesda
Background/Purpose: Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome is the most common periodic fever syndrome of childhood. Although familial clustering of the disease…
Abstract Number: 1691 • 2019 ACR/ARP Annual Meeting
Efficacy of TNF α Inhibitors for Refractory Vascular Behcet’s Disease: A Multicenter Observational Study of 27 Patients
Aysun Aksoy ¹, Ayten Yazici ², Ahmet Omma ³, Ayşe Cefle ⁴, Fatos Onen ⁵, Unal Tasdemir ⁶, Tulin Ergun ⁷, Haner Direskeneli ⁸ and Fatma Alibaz-Oner⁹, ¹Marmara University Faculty of Medicine, Division of Internal Medicine, Department of Rheumatology, Istanbul, Turkey; University of Manchester, Division of Musculoskeletal and Dermatological Sciences, Manchester, United Kingdom, Istanbul, Istanbul, Turkey, ²Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Kocaeli, Turkey, ³Health Sciences University, Ankara Numune Training and Research Hospital, Department of Rheumatology, Ankara, Turkey, ⁴Division of Rheumatology, Kocaeli University School of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, ⁵Dokuz Eylul University School of Medicine, Division of Rheumatology, İzmir, Turkey, ⁶Dokuz Eylul University, School of Medicine Division of Internal Medicine Rheumatology Department, izmir, Turkey, ⁷Marmara University School of Medicine Dermatology Department, istanbul, Turkey, ⁸Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, ⁹Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey
Background/Purpose: Vascular involvement is one of the major causes of morbidity and mortality in Behcet’s Disease (BD) patients. Immunosuppressive (IS) agents are the mainstay of…
Abstract Number: 1694 • 2019 ACR/ARP Annual Meeting
Pharmacogenetics and Pharmacodynamics of Response to Apremilast in a Phase 3 Clinical Study in Subjects with Active Behçet’s Disease
Joseph Maranville¹, Irina Medvedeva ¹, Robert Yang ¹, Mindy Chen ², Lorraine (Ruoying) Fang ², Sandra Collazo ³, Shannon McCue ³, Marla Hochfeld ³ and Peter Schafer ³, ¹Celgene Corporation, Cambridge, MA, ²Celgene Corporation, Berkeley Heights, NJ, ³Celgene Corporation, Summit, NJ
Background/Purpose: This was an exploratory analysis of genetic polymorphisms, plasma biomarkers, and blood leukocytes with clinical response in the phase 3 clinical study CC-10004-BCT-002 (NCT02307513).Methods:…
Abstract Number: 1695 • 2019 ACR/ARP Annual Meeting
Apremilast in Combination vs Monotherapy for Refractory Oral And/or Genital Ulcers in Behçet’s Disease: National Multicenter Study of 51 Cases
Belén Atienza-Mateo¹, Mónica Calderón-Goercke ², DIANA PRIETO- PENA ³, Iñigo Gonzalez-Mazon ³, Lara Sanchez-Bilbao ¹, Jose Luis Martín-Varillas ¹, Javier Loricera ⁴, Vanesa Calvo Río ¹, Jenaro Graña ⁵, Gerard Espinosa ⁶, Clara Moriano ⁷, Trinidad Pérez-Sandoval ⁷, Manuel Martín-Martínez ⁷, Elvira Díez ⁷, María Dolores García-Armario ⁸, Esperanza Martínez ⁸, Ivan Castellvi ⁹, Patricia Moya Alvarado ¹⁰, Francisca Sivera ¹¹, Jaime Calvo-Alen ¹², Isabel de la Morena ¹³, Francisco Ortiz-Sanjuán ¹⁴, José Andrés Román-Ivorra ¹⁴, Ana Pérez-Gómez ¹⁵, Sergi Heredia ¹⁶, Alejandro Olivé-Marqués ¹⁶, Águeda Prior-Español ¹⁷, Carolina Díez ¹⁸, Juan José Alegre-Sancho ¹⁹, Amparo Ybáñez ¹⁹, Ángels Martínez-Ferrer ¹⁹, Javier Narváez ²⁰, Ignasi Figeras ²¹, Ana Turrión ²², Susana Romero-Yuste ²³, Pilar Trénor ²⁴, Soledad Ojeda ²⁵, Miguel Á. González-Gay ²⁶ and Ricardo Blanco ²⁶, ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ²Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ³Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ⁴Rheumatology Department. Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ⁵Centro Médico Quirón A Coruña, A Coruña, Galicia, Spain, ⁶Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Catalonia, Spain, ⁷Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, ⁸Hospital Lluís Alcanyís, Xàtiva, Comunidad Valenciana, Spain, ⁹Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ¹⁰Hospital de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain, ¹¹Hospital General Universitario de Elda, Elda, Spain, ¹²Hospital Universitario Araba, Vitoria-Gasteiz, Spain, ¹³Hospital General Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, ¹⁴Hospital Universitario y Politécnico La Fe, Valencia, Comunidad Valenciana, Spain, ¹⁵Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain, ¹⁶Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain, ¹⁷Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ¹⁸Hospital de El Bierzo, León, Castilla y Leon, Spain, ¹⁹Hospital Universitario Doctor Peset, Valencia, Comunidad Valenciana, Spain, ²⁰Rheumatology Department, Hospital Universitari de Bellvitge, Barcelona, Catalonia, Spain, ²¹Hospital Bellvitge, Barcelona, Catalonia, Spain, ²²Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²³Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain, ²⁴Hospital Clínico Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, ²⁵Hospital Doctor Negrín, Las Palmas de Gran Canaria, Canarias, Spain, ²⁶Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
Background/Purpose: Oral and/or genital aphthous ulcers are the most common symptoms of Behçet´s disease (BD), and are often refractory to conventional treatment. The inhibitor of…
Abstract Number: 1696 • 2019 ACR/ARP Annual Meeting
Is the Risk of Tuberculosis Increased in Behçet’s Disease Compared to Other Rheumatological Disorders After Anti-TNF-α Treatment?
Ummugulsum Gazel ¹, Derya Kocakaya ², Irem Topcu ³, Hakan Karatas ⁴, Murat Karabacak ⁵, Pamir Atagunduz ⁶, Nevsun Inanc ⁷, Fatma Alibaz-Oner ⁵ and Haner Direskeneli⁸, ¹Marmara University, Faculty of Medicine, Department of Rheumatology, Istanbul, Turkey, Istanbul, Turkey, ²Marmara University Faculty of Medicine Department of Chest Diseases, Istanbul, Turkey, Istanbul, Istanbul, Turkey, ³Marmara University, School of Medicine, Istanbul,Turkey, ıstanvul, Turkey, ⁴Marmara University ,School of Medicine, Istanbul,Turkey, Istanbul, Turkey, ⁵Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, ⁶Marmara University Faculty of Medicine,Department of Rheumatology, Istanbul, Turkey, Istanbul, Turkey, ⁷Marmara University, Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, ISTANBUL, Turkey, ⁸Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey
Background/Purpose: Tumor necrosis factor (TNF)-α inhibitors are extensively utilized in the treatment of inflammatory rheumatic diseases. These agents increase the risk of tuberculosis (TB), especially…
Abstract Number: 1697 • 2019 ACR/ARP Annual Meeting
Efficacy of Apremilast for Oral Ulcers Associated with Active Behçet’s Syndrome over 64 Weeks: Long-term Results from the Japanese Subgroup in a Phase III Study
Mitsuhiro Takeno¹, Yoshiya Tanaka ², Hajime Kono ³, Shoji Sugii ⁴, Mitsumasa Kishimoto ⁵, Sue Cheng ⁶, Shannon McCue ⁷, Mindy Chen ⁸, Maria Paris ⁶ and Hiroaki Dobashi ⁹, ¹Nippon Medical School, Tokyo, Japan, ²University of Occupational and Environmental Health Japan, Kitakyushu, Japan, ³Teikyo University School of Medicine, Tokyo, Japan, ⁴Department of Rheumatic Diseases, Tokyo Metropoitan Tama Medica Center, Fuchu, Japan, ⁵Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan, ⁶Celgene Corporation, Summit, ⁷Celgene Corporation, Summit, NJ, ⁸Celgene Corporation, Berkeley Heights, NJ, ⁹Kagawa University, Kagawa, Japan
Background/Purpose: Behçet’s syndrome is a chronic, multi-system, variable vessel vasculitis characterized by painful, recurrent oral ulcers (OU) that can be disabling and may impair quality…
Abstract Number: 1698 • 2019 ACR/ARP Annual Meeting
Development of Machine Learning Models (Artificial Neural Networks) for Prediction of Vision Threatening Behçet’s Disease
Nevin Hammam¹, Eiman Abd El-Latif ², Iman I El-Gazzar ³, Nermeen Samy ⁴, Rasha A Abdel Noor ⁵, Emad El-Shebeiny ⁶, Amany R El-Najjar ⁷, Nahla N Eesa ⁸, Mohamed N Salem ⁹, Soha E Ibrahim ¹⁰, Dina F El-Essawi ¹¹, Ahmed M Elsaman ¹², Hanan M Fathi ¹³, Rehab A Sallam ¹⁴, Rawhya R El-Shereef ¹⁵, Mervat I Abd-Elazeem ¹⁶, Emtethal A Said ¹⁷, Noha M Khalil ¹⁸, Dina Shahin ¹⁹, Hanan M El-Saadany ²⁰, Marwa S ElKhalifa ²¹, Samah I Nasef ²², Ahmed M Abdalla ²³, Nermeen Noshy ⁴, Rasha M Fawzy ²⁴, Ehab Saad ²⁵, Abdel-Hafeez Moshrif ²⁶, Amira T El-Shanawany ²⁷, Yousra H Abdel-Fattah ²⁸, Hossam M Khalil ²⁹ and Tamer A Gheita ³⁰, ¹University of Alberta, Edmonton, AB, Canada, ²Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt, Alexandria, Egypt, ³Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁴Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Ain-Shams University, Cairo, Egypt, Cairo, Egypt, ⁵Internal Medicine Department, Rheumatology Unit, Tanta University, Gharbia, Egypt, Gharbia, Egypt, ⁶Internal Medicine Department, Rheumatology Unit, Menoufia University, Menoufia, Egypt, Menoufia, Egypt, ⁷Rheumatology Department, Faculty of Medicine, Zagazig University, Sharkia, Egypt, Sharkia, Egypt, ⁸Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Cairo, Egypt, ⁹Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt, Beni-Suef, Egypt, ¹⁰Rheumatology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Cairo, Egypt, ¹¹Internal Medicine Department, Rheumatology Unit (NCRRT), Atomic Energy Authority (AEA), Cairo, Egypt, Cairo, Egypt, ¹²Rheumatology Department, Faculty of Medicine, Sohag University, Sohag, Egypt., Sohag, Egypt, ¹³Rheumatology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt, Fayoum, Egypt, ¹⁴Rheumatology Department, Faculty of Medicine, Mansoura University, Dakahlia, Egypt, Dakahlia, Egypt, ¹⁵Rheumatology Department, Faculty of Medicine, Minia University, Minia, Egypt., Minia, Egypt, ¹⁶Rheumatology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt, Beni-Suef, Egypt, ¹⁷Rheumatology Department, Faculty of Medicine, Benha University, Kalubia, Egypt, Benha, Egypt, ¹⁸Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ¹⁹Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Mansoura University, Dakahlia, Egypt, Dakahlia, Egypt, ²⁰Rheumatology Department, Faculty of Medicine, Tanta University, Tanta, Egypt, Tanta, Egypt, ²¹Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Alexandria University, Alexandria, Egypt, Alexandria, Egypt, ²²Rheumatology Department, Faculty of Medicine, Suez-Canal University, Ismailia, Egypt, Ismailia, Egypt, ²³Rheumatology Department, Faculty of Medicine, Aswan University, Aswan, Egypt, Aswan, Egypt, ²⁴Rheumatology Department, Faculty of Medicine, Benha University, Kalubia, Egypt, Kalubia, Egypt, ²⁵Rheumatology Department, Faculty of Medicine, South Valley University, Qena, Egypt, Qena, Egypt, ²⁶Rheumatology Department, Faculty of Medicine, Al-Azhar University, Assuit, Egypt, Assiut, Egypt, ²⁷Rheumatology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt, Menoufia, Egypt, ²⁸Rheumatology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt, Alexandria, Egypt, ²⁹Ophthalmology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt., Beni-Suef, Egypt, ³⁰Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt., Cairo, Egypt
Background/Purpose: Ocular involvement in Behçet’s Disease (BD) is associated with chronic damage and high morbidity; however, limited evidence is available on risk factors to recognize…
Abstract Number: 1699 • 2019 ACR/ARP Annual Meeting
Disease Course of Behçet’s Syndrome Patients Not Fulfilling International Study Group Criteria at Presentation
Sinem Nihal Esatoglu¹, Seyda Bilgin ², Cem Sulu ², Vedat Hamuryudan ³, Zekayi Kutlubay ⁴, Melike Melikoglu ³, Izzet Fresko ⁵, Hasan Yazici ⁶ and Gulen Hatemi ⁷, ¹Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey, ³Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁴Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Dermatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁵Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, ⁶Academic Hospital, Istanbul, Turkey, Istanbul, Turkey, ⁷Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Behcet's Disease Research Center, Istanbul, Turkey, Istanbul, Turkey
Background/Purpose: Behçet’s syndrome (BS) shows a heterogeneous phenotype involving many organ systems and is diagnosed by recognizing the coexisting manifestations. Patients may have major organ…
Abstract Number: 1700 • 2019 ACR/ARP Annual Meeting
Clinical Characteristics and the Level Disease Activity of Behcet´s Disease in China: A Study Based on Smart System of Disease Management (SSDM)
Lingli Dong¹, Shouxin Li ¹, Fen Wang ², Zhenbiao Wu ³, Shengtao Zhang ¹, Qin Li ⁴, Henglian Wu ⁵, Zhengang Wang ⁶, Huifang Guo ⁷, Yikai Yu ¹, LingXun Shen ⁸, Yasong Li ⁹, Yang Liu ¹⁰, Tian Wang ¹¹, Peng Ji ¹², Zongwen Shuai ², Hongbin Li ¹³, Li Luo ¹², Hui Xiao ¹⁴, Yuhua Jia ¹⁵, Bing Wu ¹⁶, Shengsong Jia ¹⁵, Fei Xiao ¹⁷ and Lijun Wu ¹⁸, ¹Tongji Hospital，Tongji Medical Colllege，Huazhong University of Science and Technology, Wuhan, Hubei, China (People's Republic), ²First Affiliated Hospital of Medical University Of Anhui, Hefei, Anhui, China (People's Republic), ³The First Affiliated Hospital of The Fourth Military Medical University, Xian, Shanxi, China (People's Republic), ⁴The First People's Hospital of Yunnan Province, Kunming, Yunnan, China (People's Republic), ⁵Dongguan donghua hospital, Dongguan, Guangdong, China (People's Republic), ⁶TongRen hospital,Capital University, Bei Jing, China (People's Republic), ⁷The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China (People's Republic), ⁸Union Hospital Affiliated Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China (People's Republic), ⁹Zhejiang provincial people's hospital, Hangzhou, Zhejiang, China (People's Republic), ¹⁰Affiliated Hospital of Inner Mongolia Medical University, Huhehaote, Nei Mongol, China (People's Republic), ¹¹Beijing Anzhen Hospital, Capital Medical University, Beijing, Beijing, China (People's Republic), ¹²The first affiliated hospital of xinjiang medical university, Urumchi, China (People's Republic), ¹³The Affiliated Hospital of Inner Mongolia Medical University, Huhhot, Nei Mongol, China (People's Republic), ¹⁴Shanghai Gothic Internet Technology Co., Ltd, shanghai, Shanghai, China (People's Republic), ¹⁵Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), ¹⁶Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), ¹⁷Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic), ¹⁸People's Hospital of Xinjiang Uygur Autonomous region, Wulumuqi, Xinjiang, China (People's Republic)
Background/Purpose: Behcet´s disease (BD) is a systemic autoimmune disease that affects multiple organ systems with recurrent oral ulcers, genital ulcers and skin lesions, which might…
Abstract Number: 1701 • 2019 ACR/ARP Annual Meeting
Amyloidosis in Behcet’s Disease: Experience of a Vasculitis Centre at Silk Road
Ertugrul Cagri Bolek ¹, Enes Erul ¹, Gozde Kubra Yardımcı ¹, Levent Kilic ², Ali Akdoğan ¹ and Omer Karadag³, ¹Hacettepe University Vasculitis Centre, Ankara, Turkey, ankara, Turkey, ²Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ³Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey
Background/Purpose: Bechet’s disease (BD) is a vasculitis characterized by oral aphtae, genital ulcers, skin lesions, uveitis and with less frequent involvement of the neurological, vascular…
Abstract Number: 1705 • 2019 ACR/ARP Annual Meeting
Cyclophosphamide Therapy for the Neurologic Involvement of Behçet’s Disease – Is It Superior to Azathioprine in Preventing Relapses?
Priscila Dias Cardoso Ribeiro ¹, Eduarda Bonelli Zarur ¹, Flávia Maria Matos Melo Campos Peixoto ¹, Pedro Matos ¹, Pedro Paulo de Alcantara Pedro ¹, Rywka Tenenbaum Medeiros Golebiovsk ¹, Livia Dutra ² and Alexandre Wagner de Souza³, ¹UNIFESP-EPM, Sao Paulo, Sao Paulo, Brazil, ²Escola Paulista de Medicina (EPM), Brazil, São Paulo, Brazil, ³UNIFESP-EPM, São Paulo, Sao Paulo, Brazil
Background/Purpose: Neurologic involvement is one of the most serious cause of long-term morbidity and mortality in Behçet’s disease (BD). To date, no controlled trials have…
Abstract Number: 1706 • 2019 ACR/ARP Annual Meeting
HLA-B*51 and Its Subtypes in Brazilian Patients with Behçet’s Disease
Joice Belem ¹, Ana Maria Fraga ², Luís Eduardo Coelho Andrade ¹ and Alexandre Wagner de Souza¹, ¹UNIFESP-EPM, São Paulo, Sao Paulo, Brazil, ²Fleury Group, São Paulo, Sao Paulo, Brazil
Background/Purpose: HLA-B*51 is considered the genetic marker mostly associated with Behçet's disease (BD), mainly in countries of the silk route, where its prevalence ranges from…
Abstract Number: 1720 • 2019 ACR/ARP Annual Meeting
Pentoxifylline Gel for Oral Ulcers in Patients with Behçet’s Syndrome
Gulen Hatemi¹, Berna Yurttas ², Zekayi Kutlubay ³, Tim Cote ⁴, Semsi Burak Derkunt ⁴, Yusuf Yazici ⁵ and Hasan Yazici ⁶, ¹Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Behcet's Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ²Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University- Cerrahpasa, Behçet's Disease Research Center, Istanbul, Turkey, Istanbul, ³Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Dermatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁴Silk Road Therapeutics, Washington, DC, USA, Washington, WA, ⁵New York University School of Medicine, New York, NY, USA, New York, NY, ⁶Academic Hospital, Istanbul, Turkey, Istanbul, Turkey
Background/Purpose: Oral ulcers, the hallmark lesion of Behçet’s syndrome (BS) can be disabling and impair eating, drinking and speaking. Despite recent advances in systemic medications…
Abstract Number: 440 • 2019 ACR/ARP Annual Meeting
Disease Activity and Quality of Life in Behçet’s Syndrome: The Role of Patient Reported Outcome
Antonio Figliomeni¹, Alice Parma ¹, Viola Signorini ², Emanuele Calabresi ¹, Rosaria Talarico ¹ and Marta Mosca ³, ¹Università di Pisa, PISA, Italy, ²Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, pisa, Toscana, Italy, ³Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, Pisa, Italy
Background/Purpose: Behçet’s syndrome (BS) is a systemic vasculitis, characterised by recurrent oro-genital ulcers, ocular inflammation and skin manifestations; articular, vascular, gastro-enteric and neurological involvement may…
Abstract Number: 1932 • 2019 ACR/ARP Annual Meeting
Genetic Evidence for Recent Positive Selection of the HLA-B*51:01 Allele in the Turkish Population, a Population with a High Prevalence of HLA-B*51-Associated Behçet’s Disease
Elaine Remmers¹, Ahmet Gül ² and Daniel Kastner ¹, ¹National Human Genome Research Institute, Bethesda, MD, ²Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey
Background/Purpose: The Turkish population has one of the highest world-wide prevalence’s of the genetically complex inflammatory Behçet’s disease (BD), estimated as 4 affected per 1000…

Abstracts tagged "Behcet’s syndrome"

Genetic Susceptibility Loci for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome

Efficacy of TNF α Inhibitors for Refractory Vascular Behcet’s Disease: A Multicenter Observational Study of 27 Patients

Pharmacogenetics and Pharmacodynamics of Response to Apremilast in a Phase 3 Clinical Study in Subjects with Active Behçet’s Disease

Apremilast in Combination vs Monotherapy for Refractory Oral And/or Genital Ulcers in Behçet’s Disease: National Multicenter Study of 51 Cases

Is the Risk of Tuberculosis Increased in Behçet’s Disease Compared to Other Rheumatological Disorders After Anti-TNF-α Treatment?

Efficacy of Apremilast for Oral Ulcers Associated with Active Behçet’s Syndrome over 64 Weeks: Long-term Results from the Japanese Subgroup in a Phase III Study

Development of Machine Learning Models (Artificial Neural Networks) for Prediction of Vision Threatening Behçet’s Disease

Disease Course of Behçet’s Syndrome Patients Not Fulfilling International Study Group Criteria at Presentation

Clinical Characteristics and the Level Disease Activity of Behcet´s Disease in China: A Study Based on Smart System of Disease Management (SSDM)

Amyloidosis in Behcet’s Disease: Experience of a Vasculitis Centre at Silk Road

Cyclophosphamide Therapy for the Neurologic Involvement of Behçet’s Disease – Is It Superior to Azathioprine in Preventing Relapses?

HLA-B*51 and Its Subtypes in Brazilian Patients with Behçet’s Disease

Pentoxifylline Gel for Oral Ulcers in Patients with Behçet’s Syndrome

Disease Activity and Quality of Life in Behçet’s Syndrome: The Role of Patient Reported Outcome

Genetic Evidence for Recent Positive Selection of the HLA-B51:01 Allele in the Turkish Population, a Population with a High Prevalence of HLA-B51-Associated Behçet’s Disease