Abstracts tagged "Behcet’s syndrome"

Abstract Number: 2945 • 2016 ACR/ARHP Annual Meeting
Systematic Review: “Efficacy and Safety of Biological Versus Immunosuppressive Therapy Compared to Placebo in the Treatment of Uveitis Associated with BehçEt’s Disease.”
Ana Urruticoechea-Arana¹, Tatiana Cobo-Ibáñez², Virginia Villaverde García³, Montserrat Santos-Gómez⁴, Kelly Vargas Osorio⁵, Federico Díaz-González⁶, Leslie Fariñas Padrón⁵, Vanesa Calvo-Río⁷ and Ricardo Blanco Alonso⁷, ¹Hospital Can Misses, Ibiza, Spain, ²Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, ³Rheumatology, Hospital Universitario de Móstoles, Móstoles, Spain, ⁴Rheumatology, Hospital Can Misses, Ibiza, Spain, ⁵Family and Community Medicine, Hospital Can Misses, Ibiza, Spain, ⁶Rheumatology, Hospital Universitario de Canarias, S/C Tenerife, Spain, ⁷Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain
Background/Purpose:
Abstract Number: 2947 • 2016 ACR/ARHP Annual Meeting
Adalimumab Versus Infliximab in Cystoid Macular Edema of Uveitis Associated to BehçEt Disease. Multicenter Study of 34 Patients
Lucia Cristina Domínguez-Casas¹, Vanesa Calvo-Río¹, Ricardo Blanco², Carlos Fernández-Díaz¹, Paz Rodríguez-Cundín³, Emma Beltran⁴, Marisa Hernández-Garfella⁵, Jose M Herreras⁶, Miguel Cordero-Coma⁷, Marina Mesquida⁸, Alfredo Adan⁹, M. Victoria Hernández¹⁰, David Diaz-Valle¹¹, Ignacio Torre-Salaberri¹², Manuel Díaz-Llopis¹³, Roberto Gallego¹⁴, Olga Maiz-Alonso¹⁵, Santos Insua¹⁶, Félix Francisco¹⁷, Raquel Almodóvar González¹⁸, Oscar Ruiz Moreno¹⁹, Fernando Jiménez-Zorzo²⁰, Javier Manero²¹, Myriam Gandía²², Joan Miquel Nolla²³, Nuria Vegas-Revenga²⁴, Natalia Palmou-Fontana¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Rheumatology Department. Hospital Universitario Marqués de Valdecilla, Santander, Spain, ³Preventive Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁴Rheumatology, Hospital General Universitario de Valencia, Valencia, Spain, ⁵Ophtamology, Hospital General Universitario de Valencia, Valencia, Spain, ⁶Ophthalmology, Hospital Universitario, IOBA, Valladolid, Spain, ⁷Ophthalmology, Hospital de León, León, Spain, ⁸Ophthalmology, Hospital Clinic. Barcelona. Spain, Barcelona, Spain, ⁹Ophthalmology, Hospital Clinic de Barcelona,, Barcelona, Spain, ¹⁰Rheumatology, Hospital Clinic. Barcelona. Spain, Barcelona, Spain, ¹¹Ophthalmology Department, Hospital Clínico San Carlos, Madrid, Spain, ¹²Rheumatology, Hospital de Basurto, Bilbao, Spain, ¹³Hospital Universitario La Fe, Valencia, Spain, ¹⁴Ophtalmology, Hospital Universitario La Fe, Valencia, Spain, ¹⁵Hospital Universitario Donostia, Donostia, Spain, ¹⁶Rheumatology, Hospital Universitario Santiago de Compostela, La Coruña, Spain, ¹⁷Rheumatology, Hospital Doctor Negrín, Las Palmas de Gran Canaria, Spain, ¹⁸Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, ¹⁹Ophthalmology and Rheumatology., Hospital Miguel Servet, Zaragoza, Spain, ²⁰Hospital Miguel Servet, Zaragoza, Spain, ²¹Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, ²²Rheumatology, Hospital Puerta del Mar, Cadiz, Spain, ²³Rheumatology, Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ²⁴Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain
Background/Purpose: Cystoid macular edema (CME) is the most serious complication of uveitis and the most common cause of blindness in uveitis. Our aim was…
Abstract Number: 2948 • 2016 ACR/ARHP Annual Meeting
Fecal Calprotectin Level Is Useful in Identifying Active Disease in Behçet’s Syndrome Patients with Gastrointestinal Involvement: A Controlled Study
Sinem Nihal Esatoglu¹, Ibrahim Hatemi², Yesim Ozguler³, Gulen Hatemi³, Hafize Uzun⁴, Aykut Ferhat Celik⁵ and Hasan Yazici³, ¹Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²Istanbul University, Cerrahpasa Medical School, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, ³Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ⁴Biochemistry, Istanbul University, Cerrahpasa Medical School, Department of Biochemistry, Istanbul, Turkey, ⁵Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey
Background/Purpose: The fecal calprotectin (FC) is widely used as a non-invasive method for identifying patients with active Crohn’s disease (CD) and ulcerative colitis. Gastrointestinal involvement…
Abstract Number: 2949 • 2016 ACR/ARHP Annual Meeting
Surgical Method for Aortic Root Involvement of Behcet Disease
Byeongzu Ghang¹, Suk Jung Choo², Oh Chan Kwon³, Seokchan Hong⁴, Yong-Gil Kim⁵, Chang-Keun Lee⁵ and Bin Yoo⁵, ¹Division of Rheumatology, Department of Internal Medicine, Univerisy of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, ²Division of Thoracic and Cardiovascular Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, The Republic of, ⁴Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Department of Rheumatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Background/Purpose: Aortic regurgitation (AR) in Behcet disease is a rare but very fatal condition. Many patients require a second or third operation after simple aortic…
Abstract Number: 2959 • 2016 ACR/ARHP Annual Meeting
Baseline Endothelial Dysfunction Might Predict Immunosuppressive Need in Young, Male Behcet’s Patients with Early Disease: A Prospective Follow-up
Fatma Alibaz-Oner¹, Emrah Karatay², Belgin Aldag¹, I.Nuri Akpınar², Tulin Ergun³ and Haner Direskeneli⁴, ¹Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ²Radiology, Marmara University, School of Medicine, Istanbul, Turkey, ³Marmara University, School of Medicine, Dermatology, Istanbul, Turkey, ⁴Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Major organ involvement, especially in young males, is one of the main causes of mortality and morbidity in Behcet’s Disease (BD). However, the prognosis…
Abstract Number: 2963 • 2016 ACR/ARHP Annual Meeting
BehçEt’s Disease in Children: Eastern Mediterranean Experience
Hafize Emine Sonmez¹, Ezgi Deniz Batu¹, Betul Sozeri², Yonatan Butbul Aviel³, Yelda Bilginer⁴ and Seza Ozen⁵, ¹Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, ²Pediatric Rheumatology, Erciyes University Faculty of Medicine, Kayseri, Turkey, ³Pediatric Rheumatology, Rambam Medical Center, Haifa, Israel, ⁴Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, ANKARA, Turkey, ⁵Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey
Background/Purpose: Behçet’s disease (BD) is a variable vessel vasculitis which is more common in adults. The most widely used diagnostic criteria for adult onset disease…
Abstract Number: 2966 • 2016 ACR/ARHP Annual Meeting
Assessment of Damage in Behcet’s Disease: Do We Need a Specific Damage Index?
Ali Ugur Unal¹, Hale Gulcin Yildirim², Ceylan Cikikci², Gulsen Ozen³, Nevsun Inanc³, Pamir Atagunduz³, Tulin Ergun⁴ and Haner Direskeneli⁵, ¹Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ²Marmara University Faculty of Medicine, Istanbul, Turkey, ³Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Marmara University, School of Medicine, Dermatology, Istanbul, Turkey, ⁵Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Behcet’s Disease (BD) is a systemic vasculitis characterized by involvement of vessels of any size and type. In the course systemic vasculitis, it is…
Abstract Number: 182 • 2016 ACR/ARHP Annual Meeting
Histone Methylation in γδ T Cells As a Biomarker of Behcet’s Disease Activity
Yoshimi Aizaki^1,2, Yasuto Araki^1,2, Kojiro Sato¹, Kazuhiro Yokota¹ and Toshihide Mimura^1,2, ¹Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, ²Project Research Division, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan
Background/Purpose: Behcet’s disease (BD) is a chronic recurrent, multisystem inflammatory disorder. The phenotypic characteristics include oral aphtha, genital ulcers, uveitis and skin lesions. No specific…
Abstract Number: 2967 • 2016 ACR/ARHP Annual Meeting
Identifying Core Domains for BehçEt’s Syndrome Trials: An International Physician and Patient Delphi Exercise
Alexa Meara¹, Yesim Ozguler², Alfred Mahr³, Haner Direskeneli⁴, Ahmet Gul⁵, Yusuf Yazici⁶, Hasan Yazici², Peter A. Merkel⁷ and Gulen Hatemi², ¹Internal Medicine/Rheumatology, The Ohio State University, Columbus, OH, ²Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ³Hospital Saint-Louis, Paris, France, ⁴Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ⁵Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁶Rheumatology, New York University Medical Center, La Jolla, CA, ⁷Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: An unmet need for reliable, validated, and widely accepted outcome measures for trials in BehetÕs syndrome (BS) was identified through: i) a systematic review;…
Abstract Number: 879 • 2016 ACR/ARHP Annual Meeting
Associated Inflammatory Diseases in Takayasu’s Arteritis: The Many Faces of a Disease
Sinem Nihal Esatoglu¹, Ayse Merve Celik², Didar Ucar³, Aykut Ferhat Celik⁴, Serdal Ugurlu⁵, Gulen Hatemi⁵, Melike Melikoglu⁵, Izzet Fresko⁵, Vedat Hamuryudan⁵, Huri Ozdogan⁶, Sebahattin Yurdakul⁵, Hasan Yazici⁵ and Emire Seyahi⁵, ¹Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey, ³Istanbul University, Cerrahpasa Medical Faculty, Department of Ophthalmology, Istanbul, Turkey, ⁴Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, ⁵Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ⁶Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
Background/Purpose: Case reports and series suggest that Takayasu’s arteritis (TA) can co-exist with various inflammatory disorders. Inflammatory bowel disease [(IBD; Crohn's disease (CD) or ulcerative…
Abstract Number: 2978 • 2016 ACR/ARHP Annual Meeting
Psychiatric Involvement and Behcet’S Syndrome: Does Bipolar Disorder Represent a Clinical Feature of the Disease?
Rosaria Talarico¹, Elena Elefante², Laura Palagini³, Anna d'Ascanio⁴, Chiara Stagnaro⁴, Chiara Tani⁴, Chiara Baldini⁴, Rossella Neri¹ and Marta Mosca⁴, ¹Rheumatology Unit, University of Pisa, PISA, Italy, ²RHEUMATOLOGY UNIT, University of Pisa, Pisa, Italy, ³Psychiatric Unit, University, PISA, Italy, ⁴Rheumatology Unit, University of Pisa, Pisa, Italy
Background/Purpose: Frequency of psychiatric disorders in Behçet’s syndrome (BS) is a debated issue: while some experts attribute their presence to the chronicity of the illness,…
Abstract Number: 1202 • 2016 ACR/ARHP Annual Meeting
Characteristic Compositional and Functional Alteration of Gut Microbiota in Patients with Behcet’s Disease
Noboru Suzuki¹, Jun Shimizu² and Takao Kubota³, ¹Department of Immunology and medicine, St. Marianna University School of Medicine, Kawasaki-shi, 216-8511, Japan, ²Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ³The Japan Self Defense Forces Central Hospital, Tokyo, Japan
Background/Purpose: We have presented evidence that the frequency of helper T (Th)17 cells increased and the cells had already been activated in vivo in patients…
Abstract Number: 2979 • 2016 ACR/ARHP Annual Meeting
a Systematic Literature Review on the Treatment of Skin, Mucosa and Joint Involvement of BehçEt’s Syndrome Informing the Eular Recommendations for the Management of BehçEt’s Syndrome
Pietro Leccese¹, Yesim Ozguler², Robin Christensen³, Sinem Nihal Esatoglu⁴, Dongsik Bang⁵, Bahram Bodaghi⁶, Aykut Ferhat Celik⁷, Farida Fortune⁸, Julien Gaudric⁹, Ahmet Gul¹⁰, Ina Kotter¹¹, Alfred Mahr¹², Robert J Moots¹³, Ignazio Olivieri¹⁴, Jutta Richter¹⁵, David Saadoun¹⁶, Carlo Salvarani¹⁷, Frances Scuderi¹⁸, PETROS P SFIKAKIS¹⁹, Aksel Siva²⁰, Miles Stanford²¹, Ilknur Tugal-tutkun²², Richard West²³, Sebahattin Yurdakul², Hasan Yazici² and Gulen Hatemi², ¹Rheumatology, Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Matera, Italy, Matera, Italy, ²Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ³The Parker instutute, RC, Copenhagen, Denmark, ⁴Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ⁵Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea, Seoul, Korea, The Democratic People's Republic of, ⁶Ophthalmology, Pierre and Marie Curie University - Paris 6 Paris, France, Paris, France, ⁷Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, ⁸Dental Institute, Barts and The London NHS Trust, London, United Kingdom, ⁹Department of Vascular surgery GHPS, Paris, France, ¹⁰Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ¹¹Internal Medicine, Robert-Bosch-Hospital, Stuttgart, Germany, ¹²Hospital Saint-Louis, Paris, France, ¹³Academic Rheumatology Unit, University of Liverpool, Liverpool, United Kingdom, ¹⁴U.O. Reumatologia, A.O. Ospedale San Carlo, Potenza, Italy, ¹⁵Tubingen University, Tubingen, Germany, ¹⁶Department of Internal Medicine and Clinical Immunology, AP-HP Pitié-Salpêtrière Hospital, Paris, France, ¹⁷Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ¹⁸Patient partner, Catania, Italy, ¹⁹First Department of Propedeutic Internal Medicine, Laikon Hospital, Athens University Medical School, Athens, Greece, ²⁰Department of Neurology, Istanbul University, Cerrahpasa Medical Faculty, Department of Neurology, Istanbul, Turkey, ²¹Ophthalmology, Guy's and St. Thomas' Hospital, London, United Kingdom, ²²Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, ²³Patient partner, London, United Kingdom
A Systematic Literature Review on the Treatment of Skin, Mucosa and Joint Involvement of Behçet’s Syndrome Informing the Eular Recommendations for the Management of Behçet’s…
Abstract Number: 1285 • 2016 ACR/ARHP Annual Meeting
PET/CT Imaging in Patients with Vascular Behcet Disease
Bahtiyar Toz¹, Burak Erer¹, Sevil Kamali¹, Murat Inanc², Lale Ocal³ and Ahmet Gul¹, ¹Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, İstanbul, Turkey, ³Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey
Background/Purpose: BehetÕs disease (BD) is a multisystemic disease characterized by recurrent inflammatory manifestations. BD is classified as variable vessel vasculitis. While inflammatory thrombotic venous findings…
Abstract Number: 3043 • 2016 ACR/ARHP Annual Meeting
Dense Genotyping of Immune Related Loci in a Multi-Ethnic Behçet’s Disease Cohort Identifies Genetic Associations in a Long Noncoding RNA Near QSOX2, RASIP1/FUT2, and IL12A-AS1
Paul Renauer¹, Patrick Coit¹, Travis Hughes², Mikhail Ognenovski¹, Adam Adler³, Lourdes Ortiz-Fernández⁴, Vuslat Yilmaz⁵, Kenan Aksu⁶, Nursen Duzgun⁷, Gokhan Keser⁸, Ayse Cefle⁹, Ayten Yazici¹⁰, Andac Ergen¹¹, Erkan Alpsoy¹², Carlo Salvarani¹³, Bruno Casali¹⁴, Ina Koetter¹⁵, Alexandra Zhernakova¹⁶, Cisca Wijmenga¹⁷, Fujio Takeuchi¹⁸, Shinji Harihara¹⁹, Toshikatsu Kaburaki²⁰, Yeong Wook Song²¹, Francisco David Carmona²², Marta E. Alarcon Riquelme²³, Javier Martín²², Güher Saruhan-Direskeneli²⁴, María Francisca Gonzalez Escribano²⁵, Haner Direskeneli²⁶ and Amr H Sawalha¹, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²Division of Health Sciences and Technology, Harvard Medical School, Boston, MA, ³Oklahoma Medical Research Foundation, OK, OK, ⁴Immunology department, Hospital Universitario Virgen del Rocío, Sevilla, Spain, ⁵Istanbul University, Istanbul Faculty of Medicine, Department of Physiology, Istanbul, Turkey, ⁶İnternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, ⁷Internal Medicines, Rheumatology Department, Ankara University School of Medicine, Ankara, Turkey, ⁸Rheumatology, Ege University Medical Faculty, Izmir, Turkey, ⁹Rheumatology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey, ¹⁰Rheumatology, Kocaeli University School of Medicine, Kocaeli, Turkey, ¹¹Okmeydaný Research and Education Hospital, Istanbul, Turkey, ¹²Department of Dermatology, Akdeniz University School of Medicine, Antalya, Turkey, ¹³Rheumatology, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy, ¹⁴Molecular Biology Laboratory, Azienda Ospedaliera Arcispedale Santa Maria Nuova, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy, ¹⁵Internal Medicine IV Rheumatology, Asklepios Klinik Altona, Hamburg, Germany, ¹⁶Rheumatology and Clinical Immunology, University of Groningen, University Medical Center, Groningen, Netherlands, ¹⁷Genetics, University Medical Hospital Groningen, University of Groningen, Groningen, Netherlands, ¹⁸#504 Lab/ Dep of Internal Medicine (Allergy & Rheumatology), Faculty of Medicine, University of Toyko, Tokyo, Japan, ¹⁹Division of Anthropology, Department of Biological Science, The University of Tokyo Graduate School of Science, Tokyo, Japan, ²⁰Ophthalmology, The University of Tokyo School of Medicine, Bunkyo-ku, Japan, ²¹Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea, ²²Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, PTS-Granada, Granada, Spain, ²³Centro de Genomica e Investigación Oncológica, Pfizer-University of Granada-Junta de Andalucía, Granada, Spain, ²⁴Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, ²⁵Hospital Universitario Virgen del Rocío (IBiS,CSIC,US), Sevilla, Spain, ²⁶Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Behçet’s disease is a chronic relapsing inflammatory disease characterized by recurrent mucocutaneous involvement. We performed dense genotyping in immune related loci in a large…

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