Abstracts tagged "Behcet’s syndrome"

Abstract Number: 946 • 2019 ACR/ARP Annual Meeting
Improvements in Disease Activity and Quality of Life for up to 64 Weeks in Patients with Behçet’s Syndrome: Results from a Phase III Study
Gulen Hatemi¹, Alfred Mahr ², Mitsuhiro Takeno ³, Doyoung Kim ⁴, Melike Melikoglu ⁵, Sue Cheng ⁶, Shannon McCue ⁷, Maria Paris ⁶, Mindy Chen ⁸ and Yusuf Yazici ⁹, ¹Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Behcet's Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ²Hospital Saint-Louis, University Paris Diderot, Paris, France, ³Nippon Medical School, Tokyo, Japan, ⁴Yonsei University College of Medicine and Severance Hospital, Seoul, Republic of Korea, ⁵Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁶Celgene Corporation, Summit, ⁷Celgene Corporation, Summit, NJ, ⁸Celgene Corporation, Berkeley Heights, NJ, ⁹New York University School of Medicine, New York
Background/Purpose: Behçet’s syndrome is a chronic, multi-system inflammatory disorder characterized by painful, recurrent oral ulcers (OU) that can impair quality of life (QoL). Apremilast (APR),…
Abstract Number: 949 • 2019 ACR/ARP Annual Meeting
Assessment of Femoral Vein Wall Thickness with Doppler Ultrasound Can Be a Diagnostic Tool for Behcet’s Disease
Fatma Alibaz-Oner¹, RABIA ERGELEN ², YASIN YILDIZ ³, Ayten Yazici ⁴, AYDAN MUTIS ⁵, ZEYNEP ERTURK ³, MUSTAFA ALDAG ⁶, Ayşe Cefle ⁷, Bahar Artim-Esen ⁸, GONCA MUMCU ⁹, TULIN ERGUN ¹⁰ and Haner Direskeneli ¹¹, ¹Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, ²MARMARA UNIVERSITY, SCHOOL OF MEDICINE, RADIOLOGY, ISTANBUL, Turkey, ³MARMARA UNIVERSITY, SCHOOL OF MEDICINE, RHEUMATOLOGY, ISTANBUL, Turkey, ⁴Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Kocaeli, Turkey, ⁵MARMARA UNIVERSITY, SCHOOL OF MEDICINE, RHEUMATOLOGY, ISTANBUL, Tuvalu, ⁶BAHCESEHIR UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF CARDIOVASCULAR SURGERY, ISTANBUL, Turkey, ⁷Division of Rheumatology, Kocaeli University School of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, ⁸Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ⁹Marmara, University, Department of Health Management, Marmara University School of Health Sciences, Istanbul, Turkey, ISTANBUL, Turkey, ¹⁰MARMARA UNIVERSITY, SCHOOL OF MEDICINE, DERMATOLOGY, Istanbul, Istanbul, Turkey, ¹¹Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey
Background/Purpose: Behcet's disease(BD) is a uniqe systemic vasculitis mainly involving venous vessels in contrast to other systemic vasculitides. Diagnosing BD is a challenge, especially in…
Abstract Number: 1690 • 2019 ACR/ARP Annual Meeting
The Long-term Outcome of Patients with Arthritis of Behçet’s Disease
Hirotoshi Kikuchi¹, Takafumi Tomizuka ¹, Kurumi Asako ¹, Hajime Kono ¹ and Shunsei Hirohata ², ¹Teikyo University School of Medicine, Tokyo, Japan, ²Nobuharra Hospital & Institute of Biomechanics, Tokyo, Japan
Background/Purpose: Behçet’s disease (BD) is characterized by recurrent aphthous stomatitis, eye lesions, skin lesions, and genital ulcer. In addition to these symptoms, Behçet’s disease is…
Abstract Number: 1789 • 2018 ACR/ARHP Annual Meeting
Mucocutaneous Activity Index As a Patient-Reported Outcome Measure in Behcet’s Disease: A Multi-Center Study from Turkey
Haner Direskeneli, Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Organ-specific patient-reported outcome (PRO) measures may help management decisions of Behcet’s disease (BD). The aim of this prospective study was to evaluate the factors…
Abstract Number: 1810 • 2018 ACR/ARHP Annual Meeting
Initial Visit Symptoms in Probable Behçet’s Predictive of ISG Criteria Behçet’s: Data from New York and Amsterdam Cohorts
Floor Kerstens¹, Christopher J. Swearingen², Franktien Turkstra¹ and Yusuf Yazici³, ¹Amsterdam Rheumatology & Immunology Centre - Reade, Amsterdam, Netherlands, ²Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Behçet’s syndrome (BS) is formally diagnosed using the International Study Group (ISG) criteria, where recurrent oral ulceration and any two other symptoms (recurrent genital…
Abstract Number: 1790 • 2018 ACR/ARHP Annual Meeting
An Unmet Need for Oral Ulcer Activity in Patients with Behcet’s Disease: A Multi-National Study
Gonca Mumcu¹, Adebowale Adesanya², Aysun Aksoy³, Joice Moraes Faria M Belem⁴, Natalia Borges Cardin⁴, Fatma Alibaz-Oner⁵, Tulin Ergun⁶, Nevsun Inanc⁷, Alexandre W.S. Souza⁸, Wafa Madanat⁹, Farida Fortune¹⁰ and Haner Direskeneli⁷, ¹Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, ²Barts and The London, School of Medicine and Dentistry, Institute of Dentistry, Clinical and Diagnostic Oral Sciences, London, UK, London, United Kingdom, ³Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, ⁴Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ⁵Şerifali mahallesi İbrahim Hakkı sokak. Lavella 4 sitesi. B blok, D:22 Umraniye, Şerifali mahallesi İbrahim Hakkı sokak. Lavella 4 sitesi. B blok, D:22 Umraniye, Istanbul, Turkey, ⁶Department of Dermatology, Faculty of Medicine, Marmara University, Istanbul, Turkey, ⁷Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ⁸Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, ⁹Jordan’s Friends of Behcet’s disease Patients Society, Medical department, Amman, Jordan, Amman, Jordan, ¹⁰Dental Institute, Barts and The London NHS Trust, London, United Kingdom
Background/Purpose: Efficacy of current management approaches for oral ulcer treatment in routine clinical practice is insufficiently explored in Behcet’s disease (BD) patients. The aim of…
Abstract Number: 1811 • 2018 ACR/ARHP Annual Meeting
Efficacy and Safety of Interferon α2a As an Add-on Treatment for Refractory Behcet’s Uveitis
Jing Shi¹, Chan Zhao², Jiaxin Zhou³, JinJing Liu¹, Fei Gao², Xiaofeng Zeng⁴, Meifen Zhang² and Wenjie Zheng¹, ¹Rheumatology, Peking Union Medical College Hospital, Beijing, China, ²Department of Ophthalmology, Peking Union Medical College Hospital, Beijing, China, ³Department of Rheumatology, Peking Union Medical College Hospital, Beijing, China, ⁴Rheumatology, Peking Union Medical College and Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China
Background/Purpose: Uveitis is one of the leading causes of morbidity in Behcet’s patients which may result in irreversible vision loss. Evidence is accumulating that interferon…
Abstract Number: 1791 • 2018 ACR/ARHP Annual Meeting
Efficacy of Apremilast for Oral Ulcers Associated with Active Behçet’s Syndrome in a Phase III Study: A Prespecified Analysis By Baseline Patient Demographics and Disease Characteristics
Gulen Hatemi¹, Alfred Mahr², Mitsuhiro Takeno³, Do-Young Kim⁴, Melike Melikoglu¹, Sue Cheng⁵, Shannon McCue⁵, Maria Paris⁵, Mindy Chen⁵ and Yusuf Yazici⁶, ¹Istanbul University Cerrahpasa Medical School, Istanbul, Turkey, ²Hospital Saint-Louis, University Paris Diderot, Paris, France, ³Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ⁴Yonsei University College of Medicine and Severance Hospital, Seoul, Korea, Republic of (South), ⁵Celgene Corporation, Summit, NJ, ⁶New York University School of Medicine, New York, NY
Background/Purpose: Behçet’s syndrome is a chronic, multi-system inflammatory disorder characterized by recurrent oral ulcers (OU) that can be disabling and negatively affect quality of life.…
Abstract Number: 1812 • 2018 ACR/ARHP Annual Meeting
Characterization and Prevalence of Morbus Behçet in Switzerland
Sabine Adler¹, Rahel Villiger², Lukas Buetikofer³ and Peter M. Villiger⁴, ¹Department of Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern, Bern, Switzerland, ²Rheumatology, Immunology and Allergology, University Hospital Bern, Switzerland, Bern, Switzerland, ³Clinical Trials Unit, University of Bern, Bern, Switzerland, ⁴Rheumatology and Clin Immunol, Bern, Switzerland
Background/Purpose: To evaluate the clinical presentation of patients with Morbus Behçet (MB) in a cohort from Switzerland and to calculate the prevalence of MB in…
Abstract Number: 1794 • 2018 ACR/ARHP Annual Meeting
Venous Vessel Wall Thickness in Lower Extremity Is Increased in Male Behcet’s Disease Patients
Fatma Alibaz-Oner¹, Rabia Ergelen², Aydan Mutiş³, Zeynep Erturk¹, Ruslan Asadov⁴, Tulin Ergun⁵ and Haner Direskeneli⁶, ¹Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, ²Marmara University School of Medicine, Radiology, ISTANBUL, Turkey, ³Marmara University, School of Medicine, Rheumatology, ISTANBUL, Turkey, ⁴Marmara University School of Medicine, Radiology, Istanbul, Turkey, ⁵Marmara University, School of Medicine, Dermatology, Istanbul, Turkey, ⁶Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Vascular involvement is seen in up to 40% of the patients with Behcet's Disease (BD), especially in young males and is one of the…
Abstract Number: 1813 • 2018 ACR/ARHP Annual Meeting
Non-Aphthous Beginning As an Independent Risk Factor for the Course of Behçet’s Disease
Muhammed Aydin¹, Bahar Artim-Esen¹, Murat Inanc², Lale Ocal¹ and Ahmet Gül¹, ¹Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, İstanbul, Turkey
Background/Purpose: Behçet disease (BD) is a multisystem inflammatory disorder characterized by recurrent manifestations in mucocutaneous tissues, eyes, joints, blood vessels, intestines and brain. Since there…
Abstract Number: 1795 • 2018 ACR/ARHP Annual Meeting
New Major Organ Involvement Is Lower in Young Male Behçet’s Patients Compared to Retrospective Series: Five-Year Results of a Prospective Cohort
Fatma Alibaz-Oner¹, Belgin Aldag², Emrah Karatay³, Gonca Mumcu⁴, Tulin Ergun⁵ and Haner Direskeneli⁶, ¹Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, ²Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ³Radiology, Marmara University, School of Medicine, Istanbul, Turkey, ⁴Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, ⁵Marmara University, School of Medicine, Dermatology, Istanbul, Turkey, ⁶Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Major organ involvement such as vascular or ocular disease, especially in young males, is one of the main causes of mortality and morbidity in…
Abstract Number: 1814 • 2018 ACR/ARHP Annual Meeting
Interferon-Alpha for the Management of Lower Extremity Deep Vein Thrombosis in Behcet’s Syndrome: A Case Series
Yesim Ozguler¹, Gulen Hatemi², Firat Cetinkaya³, Koray Tascilar⁴, Serdal Ugurlu¹, Emire Seyahi¹, Hasan Yazici¹ and Melike Melikoglu¹, ¹Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²Istanbul University Cerrahpasa Medical School, Istanbul, Turkey, ³Istanbul University, Cerrahpasa Medical Faculty, Department of Radiology, Istanbul, Turkey, ⁴Numune Research and Teaching Hospital, Ankara, Turkey
Background/Purpose: Lower extremity deep vein thrombosis (LEDVT) is a disabling complication of Behcet’s syndrome (BS). Relapses are frequent and cause permanent disability due to post-thrombotic…
Abstract Number: 1796 • 2018 ACR/ARHP Annual Meeting
Retrospective Analysis of Initial Presentation Findings of Behcet’s Syndrome throughout 4 Decades
Elif Dincses¹, Yesim Ozguler², Didar Ucar³, Yilmaz Ozyazgan⁴, Serdal Ugurlu², Gulen Hatemi², Melike Melikoglu², Sebahattin Yurdakul², Hasan Yazici⁵ and Emire Seyahi², ¹Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, İstanbul, Turkey, ²Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ³Ophthalmology, Istanbul University, Cerrahpasa Medical Faculty, Department of Ophthalmology, Istanbul, Turkey, ⁴Istanbul University, Cerrahpasa Medical Faculty, Department of Ophthalmology, Istanbul, Turkey, ⁵Istanbul Academic Hospital, Istanbul, Turkey
Background/Purpose: There is some evidence that incident Behcet’s syndrome (BS) might be becoming less severe (1, 2). We compared clinical findings at presentation of BS…
Abstract Number: 1815 • 2018 ACR/ARHP Annual Meeting
Aneurysmal Lesions in Behcet’s Disease: A Report of 69 Cases from a Single Center
Jiaxin Zhou¹, Jing Shi², Xiuhua Wu², JinJing Liu² and Wenjie Zheng², ¹Department of Rheumatology, Peking Union Medical College Hospital, Beijing, China, ²Rheumatology, Peking Union Medical College Hospital, Beijing, China
Background/Purpose: To analyze the clinical features of patients with Behcet’s disease(BD) complicated with aneurysmal lesions. Methods: We retrospectively reviewed the clinical data of patients with…